| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Diane C Fingar | |
| Kezhen Huang | |||
| P2860 | cites work | TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1 | Q24293153 |
| A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1 | Q24294219 | ||
| Activation of mTORC2 by association with the ribosome | Q24294876 | ||
| Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 | ||
| Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1 | Q24298767 | ||
| Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton | Q24299873 | ||
| PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase | Q24300915 | ||
| mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E | Q24301780 | ||
| mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery | Q24302549 | ||
| Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action | Q24302566 | ||
| Identification of Protor as a novel Rictor-binding component of mTOR complex-2 | Q24303936 | ||
| mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide | Q24305343 | ||
| Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive | Q24306328 | ||
| Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids | Q24306330 | ||
| Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway | Q24307790 | ||
| SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth | Q24309283 | ||
| Mechanism of activation of protein kinase B by insulin and IGF-1 | Q24309528 | ||
| DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival | Q24311448 | ||
| The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1 | Q24315566 | ||
| SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling | Q24320106 | ||
| Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling | Q24323370 | ||
| mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1) | Q24324148 | ||
| AMPK phosphorylation of raptor mediates a metabolic checkpoint | Q24329244 | ||
| Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation | Q24337405 | ||
| Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling | Q24536092 | ||
| Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis. | Q24537185 | ||
| Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex | Q24559347 | ||
| Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development | Q24563399 | ||
| Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase | Q24564747 | ||
| The AMPK signalling pathway coordinates cell growth, autophagy and metabolism | Q24616273 | ||
| The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation | Q24616946 | ||
| Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy | Q24628724 | ||
| Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology | Q24634012 | ||
| mTOR signaling in growth control and disease | Q24634174 | ||
| Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1 | Q24645183 | ||
| The TSC1-TSC2 complex: a molecular switchboard controlling cell growth | Q24645204 | ||
| Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation | Q24648213 | ||
| AKT/PKB signaling: navigating downstream | Q24657857 | ||
| Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling | Q24677061 | ||
| A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling | Q24678327 | ||
| Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity | Q24680264 | ||
| RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1 | Q24682697 | ||
| mTOR kinase structure, mechanism and regulation | Q27677954 | ||
| TSC2 mediates cellular energy response to control cell growth and survival | Q27860970 | ||
| Synthesis of the translational apparatus is regulated at the translational level | Q34058830 | ||
| Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase. | Q34063643 | ||
| Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα). | Q34139142 | ||
| Rac1 regulates the activity of mTORC1 and mTORC2 and controls cellular size | Q34176565 | ||
| Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1. | Q34182185 | ||
| Signals from the lysosome: a control centre for cellular clearance and energy metabolism | Q34340780 | ||
| mTORC1: turning off is just as important as turning on. | Q34404341 | ||
| Phospholipase D1 is an effector of Rheb in the mTOR pathway. | Q34786317 | ||
| Regulation of cellular growth by the Drosophila target of rapamycin dTOR | Q35206467 | ||
| Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin | Q35206496 | ||
| Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family | Q35234179 | ||
| Phosphatidic acid activates mammalian target of rapamycin complex 1 (mTORC1) kinase by displacing FK506 binding protein 38 (FKBP38) and exerting an allosteric effect | Q35313512 | ||
| Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling | Q35370616 | ||
| Class III PI-3-kinase activates phospholipase D in an amino acid-sensing mTORC1 pathway | Q35503921 | ||
| RalA functions as an indispensable signal mediator for the nutrient-sensing system | Q35676903 | ||
| mTOR complex 2 signaling and functions | Q35878519 | ||
| A unifying model for mTORC1-mediated regulation of mRNA translation. | Q35945036 | ||
| The updated biology of hypoxia-inducible factor | Q36001994 | ||
| Rab5 proteins regulate activation and localization of target of rapamycin complex 1. | Q36033140 | ||
| Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1. | Q36127992 | ||
| Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes | Q36618911 | ||
| Stress and mTORture signaling | Q36623669 | ||
| The multifaceted role of mTORC1 in the control of lipid metabolism | Q36659049 | ||
| Regulation of mTOR by phosphatidic acid? | Q36702428 | ||
| The TSC1-TSC2 complex is required for proper activation of mTOR complex 2 | Q36710799 | ||
| Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation | Q36971030 | ||
| ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression | Q37130845 | ||
| mTORC1 phosphorylation sites encode their sensitivity to starvation and rapamycin | Q37166913 | ||
| Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases | Q37208207 | ||
| A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS. | Q37213565 | ||
| Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR) | Q37257487 | ||
| Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth. | Q37275196 | ||
| mTOR signaling: PLD takes center stage | Q37300979 | ||
| An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1 | Q29614563 | ||
| Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism | Q29614737 | ||
| Activation of a metabolic gene regulatory network downstream of mTOR complex 1 | Q29615179 | ||
| AMPK: a nutrient and energy sensor that maintains energy homeostasis | Q29615410 | ||
| Molecular mechanisms of mTOR-mediated translational control | Q29615529 | ||
| mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase | Q29616153 | ||
| Insulin signalling to mTOR mediated by the Akt/PKB substrate PRAS40 | Q29617097 | ||
| Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression | Q29617473 | ||
| Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E | Q29618009 | ||
| mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway | Q30425628 | ||
| Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR. | Q30436040 | ||
| Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation | Q30439476 | ||
| A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB | Q30508509 | ||
| The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis | Q30524831 | ||
| Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner. | Q33668452 | ||
| The late endosome is essential for mTORC1 signaling | Q33689824 | ||
| mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action | Q33706924 | ||
| The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. | Q33928657 | ||
| Phospholipase D and the maintenance of phosphatidic acid levels for regulation of mammalian target of rapamycin (mTOR) | Q34044538 | ||
| TOR controls translation initiation and early G1 progression in yeast | Q27931425 | ||
| Leucyl-tRNA synthetase controls TORC1 via the EGO complex | Q27939627 | ||
| GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR | Q28115142 | ||
| p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling | Q28117922 | ||
| Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro | Q28138191 | ||
| TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function | Q28204144 | ||
| Phosphatidic acid-mediated mitogenic activation of mTOR signaling | Q28208274 | ||
| The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses | Q28240102 | ||
| A mammalian protein targeted by G1-arresting rapamycin-receptor complex | Q28243712 | ||
| Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis | Q28246808 | ||
| Rheb binds and regulates the mTOR kinase | Q28247033 | ||
| Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks | Q28255399 | ||
| mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s | Q28258807 | ||
| SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity | Q28262782 | ||
| Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1 | Q28276788 | ||
| Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast | Q28277565 | ||
| Immunopharmacology of rapamycin | Q28285198 | ||
| RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs | Q28286431 | ||
| Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation | Q28291584 | ||
| PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding | Q28302887 | ||
| Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells | Q28305483 | ||
| Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB | Q28306356 | ||
| Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome | Q28307704 | ||
| Hierarchical phosphorylation of the translation inhibitor 4E-BP1 | Q28363125 | ||
| Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue | Q28367688 | ||
| AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 | Q28506431 | ||
| The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins | Q28507365 | ||
| The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4 | Q28508613 | ||
| The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C | Q28587901 | ||
| Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis | Q28595034 | ||
| The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR | Q28610067 | ||
| Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway | Q28646919 | ||
| Bidirectional transport of amino acids regulates mTOR and autophagy | Q29614476 | ||
| Regulation of TORC1 by Rag GTPases in nutrient response | Q29614478 | ||
| Not all substrates are treated equally: implications for mTOR, rapamycin-resistance and cancer therapy | Q37386580 | ||
| The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1. | Q37402791 | ||
| Roles for PI(3,5)P2 in nutrient sensing through TORC1. | Q37669247 | ||
| K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells | Q37677233 | ||
| Rapamycin: one drug, many effects | Q37679469 | ||
| The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila | Q37694347 | ||
| mTOR in aging, metabolism, and cancer | Q38073906 | ||
| Targeting the unfolded protein response in disease. | Q38132652 | ||
| Making new contacts: the mTOR network in metabolism and signalling crosstalk | Q38189969 | ||
| p62 is a key regulator of nutrient sensing in the mTORC1 pathway. | Q38666713 | ||
| Toward a comprehensive characterization of a human cancer cell phosphoproteome. | Q39237219 | ||
| Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase | Q39599480 | ||
| ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1). | Q39632887 | ||
| mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs | Q39699300 | ||
| Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2. | Q39700543 | ||
| PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR. | Q39728074 | ||
| mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling | Q39765614 | ||
| Rictor is a novel target of p70 S6 kinase-1. | Q39771171 | ||
| Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis | Q40002274 | ||
| Regulation of the small GTPase Rheb by amino acids. | Q40371799 | ||
| hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase | Q40392574 | ||
| Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling | Q40711462 | ||
| Identification of a conserved motif required for mTOR signaling | Q40736711 | ||
| Insulin signal transduction and the IRS proteins | Q41048272 | ||
| mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. | Q41792378 | ||
| Activating transcription factor 4 and CCAAT/enhancer-binding protein-beta negatively regulate the mammalian target of rapamycin via Redd1 expression in response to oxidative and endoplasmic reticulum stress | Q42172164 | ||
| mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8. | Q42500373 | ||
| mTOR, AMBRA1, and autophagy: an intricate relationship | Q42790841 | ||
| mTOR kinase domain phosphorylation promotes mTORC1 signaling, cell growth, and cell cycle progression | Q42793655 | ||
| Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2. | Q43170208 | ||
| TSC on the peroxisome controls mTORC1. | Q44131710 | ||
| Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies | Q45067792 | ||
| Rapamycin resistance: mTORC1 substrates hold some of the answers | Q45249494 | ||
| Rapamycin inhibits mTORC1, but not completely. | Q46035927 | ||
| The pharmacology of mTOR inhibition | Q46041824 | ||
| MAP4K3 regulates body size and metabolism in Drosophila | Q47070049 | ||
| Glutaminolysis activates Rag-mTORC1 signaling. | Q52301079 | ||
| Ribosomal protein S6 kinase activity controls the ribosome biogenesis transcriptional program. | Q54457299 | ||
| P304 | page(s) | 79-90 | |
| P577 | publication date | 2014-09-19 | |
| P1433 | published in | Seminars in Cell & Developmental Biology | Q14330411 |
| P1476 | title | Growing knowledge of the mTOR signaling network | |
| P478 | volume | 36 |
| Q54977058 | "Immune TOR-opathies," a Novel Disease Entity in Clinical Immunology. |
| Q47135530 | A high sucrose and high fat diet induced the development of insulin resistance in the skeletal muscle of Bama miniature pigs through the Akt/GLUT4 pathway |
| Q92666563 | AMPK directly activates mTORC2 to promote cell survival during acute energetic stress |
| Q37699205 | Aberrant overexpression of ADAR1 promotes gastric cancer progression by activating mTOR/p70S6K signaling |
| Q38635465 | Akt Inhibitor Perifosine Prevents Epileptogenesis in a Rat Model of Temporal Lobe Epilepsy |
| Q51165149 | Amino Acid Catabolism in Multiple Sclerosis Affects Immune Homeostasis. |
| Q35860920 | Autophagy modulates articular cartilage vesicle formation in primary articular chondrocytes |
| Q38732613 | Autophagy suppression sensitizes glioma cells to IMP dehydrogenase inhibition-induced apoptotic death. |
| Q47407747 | BCA3 contributes to the malignant progression of hepatocellular carcinoma through AKT activation and NF-κB translocation |
| Q38267155 | Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling. |
| Q26777407 | Biochemical Genetic Pathways that Modulate Aging in Multiple Species |
| Q38618035 | Cap-independent translation ensures mTOR expression and function upon protein synthesis inhibition. |
| Q38717418 | Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses |
| Q35213241 | Characterization of the transcriptome of fast and slow muscle myotomal fibres in the pacu (Piaractus mesopotamicus) |
| Q37656557 | Clinical and Molecular Assessment in a Female with Fragile X Syndrome and Tuberous Sclerosis |
| Q89357329 | Co-targeting PLK1 and mTOR induces synergistic inhibitory effects against esophageal squamous cell carcinoma |
| Q36214162 | Co-targeting of Akt and Myc inhibits viability of lymphoma cells from Lck-Dlx5 mice |
| Q54171582 | Colorectal carcinomas with submucosal invasion (pT1): analysis of histopathological and molecular factors predicting lymph node metastasis. |
| Q52730266 | Combined Inhibition of mTOR and CDK4/6 Is Required for Optimal Blockade of E2F Function and Long-term Growth Inhibition in Estrogen Receptor-positive Breast Cancer. |
| Q51765180 | Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins. |
| Q42018263 | Construction of competitive endogenous RNA network reveals regulatory role of long non-coding RNAs in type 2 diabetes mellitus |
| Q33893456 | Control of Germline Stem Cell Lineages by Diet and Physiology |
| Q36075067 | Dietary restriction, mitochondrial function and aging: from yeast to humans |
| Q42335725 | Differentiation capacities of skeletal muscle satellite cells in Lantang and Landrace piglets. |
| Q92493364 | Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition |
| Q37257953 | Effects of a brief high-fat diet and acute exercise on the mTORC1 and IKK/NF-κB pathways in rat skeletal muscle |
| Q96128419 | Emerging role of mTOR in tumor immune contexture: Impact on chemokine-related immune cells migration |
| Q47356910 | Evaluation of the Effect of Everolimus on Retinal Pigment Epithelial Cells and Experimental Proliferative Vitreoretinopathy |
| Q47588788 | GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation. |
| Q37536133 | Genetics of tuberous sclerosis complex: implications for clinical practice |
| Q38682364 | Gold nanoparticles enhance the differentiation of embryonic stem cells into dopaminergic neurons via mTOR/p70S6K pathway. |
| Q48304962 | IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes |
| Q91987838 | IKBKE inhibits TSC1 to activate the mTOR/S6K pathway for oncogenic transformation |
| Q26800159 | IL-15-PI3K-AKT-mTOR: A Critical Pathway in the Life Journey of Natural Killer Cells |
| Q54938477 | Importance of Serum Amino Acid Profile for Induction of Hepatic Steatosis under Protein Malnutrition. |
| Q35599430 | Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene |
| Q26748964 | Influence of Acute and Chronic Exercise on Glucose Uptake |
| Q50875345 | Insulin signaling and skeletal muscle atrophy and autophagy in transition dairy cows either overfed energy or fed a controlled energy diet prepartum. |
| Q36518337 | Interferon γ (IFNγ) Signaling via Mechanistic Target of Rapamycin Complex 2 (mTORC2) and Regulatory Effects in the Generation of Type II Interferon Biological Responses |
| Q37673649 | Intestinal Epithelial-Specific mTORC1 Activation Enhances Intestinal Adaptation After Small Bowel Resection |
| Q37587229 | Intestinal Microbiota-Derived GABA Mediates Interleukin-17 Expression during Enterotoxigenic Escherichia coli Infection |
| Q57470226 | Intestinal epithelial cell-specific Raptor is essential for high fat diet-induced weight gain in mice |
| Q57479644 | Knockout of Raptor destabilizes ornithine decarboxylase mRNA and decreases binding of HuR to the ODC transcript in cells exposed to ultraviolet-B irradiation |
| Q38766223 | Mammalian target of rapamycin complex (mTOR) pathway modulates blood-testis barrier (BTB) function through F-actin organization and gap junction |
| Q47656486 | Mechanistic target of rapamycin complex 1 and 2 in human temporal lobe epilepsy. |
| Q49515435 | Meta-analysis of the prognostic value of p-4EBP1 in human malignancies |
| Q38442728 | Metabolic control of signalling pathways and metabolic auto-regulation |
| Q93156707 | MiR-152 influences osteoporosis through regulation of osteoblast differentiation by targeting RICTOR |
| Q52316968 | Modulation of the secretory pathway by amino-acid starvation. |
| Q37687122 | Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer |
| Q38587970 | Muscle wasting as main evidence of energy impairment in cancer cachexia: future therapeutic approaches |
| Q94545735 | Nucleobindin-2 enhances the epithelial-mesenchymal transition in renal cell carcinoma |
| Q55333391 | Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice. |
| Q38291857 | Oocyte-dependent activation of MTOR in cumulus cells controls the development and survival of cumulus-oocyte complexes |
| Q93351370 | PI3K/Akt/mTOR signaling pathway participates in Streptococcus uberis-induced inflammation in mammary epithelial cells in concert with the classical TLRs/NF-ĸB pathway |
| Q92670754 | Pathogenesis and treatment of autoimmune rheumatic diseases |
| Q36902375 | Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension |
| Q39128991 | Phosphatidic acid: biosynthesis, pharmacokinetics, mechanisms of action and effect on strength and body composition in resistance-trained individuals. |
| Q91530322 | Phosphorylated Rho-GDP directly activates mTORC2 kinase towards AKT through dimerization with Ras-GTP to regulate cell migration |
| Q91896679 | Protective Role of mTOR in Liver Ischemia/Reperfusion Injury: Involvement of Inflammation and Autophagy |
| Q52359210 | Proteomic analysis of corneal endothelial cell-descemet membrane tissues reveals influence of insulin dependence and disease severity in type 2 diabetes mellitus. |
| Q92316553 | RAPTOR promotes colorectal cancer proliferation by inducing mTORC1 and upregulating ribosome assembly factor URB1 |
| Q35728231 | RNAseq analysis of fast skeletal muscle in restriction-fed transgenic coho salmon (Oncorhynchus kisutch): an experimental model uncoupling the growth hormone and nutritional signals regulating growth |
| Q36739499 | Recent Advances in Adipose mTOR Signaling and Function: Therapeutic Prospects |
| Q36053193 | Redox regulation of autophagy in healthy brain and neurodegeneration |
| Q26764871 | Regulation of mTORC1 by growth factors, energy status, amino acids and mechanical stimuli at a glance |
| Q38964715 | Reversal of phenotypes of cellular senescence by pan-mTOR inhibition. |
| Q50133371 | Rictor/TORC2 mediates gut-to-brain signaling in the regulation of phenotypic plasticity in C. elegans. |
| Q41583239 | SH3BP4, a novel pigmentation gene, is inversely regulated by miR-125b and MITF. |
| Q38690087 | Signaling pathways regulating blood-tissue barriers - Lesson from the testis |
| Q26749011 | Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular Effects |
| Q55365628 | Starvation tactics using natural compounds for advanced cancers: pharmacodynamics, clinical efficacy, and predictive biomarkers. |
| Q40977960 | Stress and inflammatory gene networks in bovine liver are altered by plane of dietary energy during late pregnancy. |
| Q38563516 | Studying polyglutamine diseases in Drosophila. |
| Q89878907 | TLR2 Signaling Pathway Combats Streptococcus uberis Infection by Inducing Mitochondrial Reactive Oxygen Species Production |
| Q98164379 | Targeted therapies in gynecological cancers: a comprehensive review of clinical evidence |
| Q92874380 | Targeting Metabolic Reprogramming in Acute Myeloid Leukemia |
| Q37057414 | The Emergence of Physiology and Form: Natural Selection Revisited |
| Q47576629 | The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists |
| Q51197594 | The Novel mTOR Complex 1/2 Inhibitor P529 Inhibits Human Lung Myofibroblast Differentiation. |
| Q26851852 | The PI3K/Akt/mTOR pathway in ovarian cancer: therapeutic opportunities and challenges |
| Q39991963 | The Role of Embryonic Stem Cell-expressed RAS (ERAS) in the Maintenance of Quiescent Hepatic Stellate Cells |
| Q37571664 | The Role of Mitochondria and Oxidative/Antioxidative Imbalance in Pathobiology of Chronic Obstructive Pulmonary Disease |
| Q38714678 | The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth |
| Q37336151 | The Werner syndrome RECQ helicase targets G4 DNA in human cells to modulate transcription. |
| Q43727717 | The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1-restricted autophagy in Caenorhabditis elegans |
| Q26751155 | The mTOR pathway in obesity driven gastrointestinal cancers: Potential targets and clinical trials |
| Q38661458 | The mTOR/p70S6K1 signaling pathway in renal fibrosis of children with immunoglobulin A nephropathy |
| Q41423362 | The mTORC1-4E-BP-eIF4E axis controls de novo Bcl6 protein synthesis in T cells and systemic autoimmunity. |
| Q38559901 | The opposing actions of target of rapamycin and AMP-activated protein kinase in cell growth control |
| Q35685257 | The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development |
| Q36782275 | The pentacyclic triterpenoid, plectranthoic acid, a novel activator of AMPK induces apoptotic death in prostate cancer cells |
| Q52562797 | The plant hormone abscisic acid regulates the growth and metabolism of endophytic fungus Aspergillus nidulans. |
| Q39203339 | The role of metabolic states in development and disease. |
| Q26764947 | Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve |
| Q52311378 | Unitary Physiology. |
| Q39011882 | Unraveling the regulation of mTORC2 using logical modeling. |
| Q54978861 | mTOR Signaling and Neural Stem Cells: The Tuberous Sclerosis Complex Model. |
| Q49486147 | mTOR as Regulator of Lifespan, Aging, and Cellular Senescence: A Mini-Review |
| Q37743486 | mTOR function and therapeutic targeting in breast cancer |
| Q34924612 | mTOR inhibition rescues osteopenia in mice with systemic sclerosis |
| Q58795101 | mTORC Inhibitors as Broad-Spectrum Therapeutics for Age-Related Diseases |
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