Development of a reverse genetics system for respiratory syncytial virus long strain and an immunogenicity study of the recombinant virus

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Development of a reverse genetics system for respiratory syncytial virus long strain and an immunogenicity study of the recombinant virus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/1743-422X-11-142
P8608Fatcat IDrelease_yi4bxeirkjfh5b36mvhug7wkjy
P932PMC publication ID4254404
P698PubMed publication ID25107552

P2093author name stringGuoming Li
Bing Hu
Yuanding Chen
Xuhua Guan
Yongzhong Jiang
Jianbo Zhan
Zhizheng Fang
Jiawei Jiang
P2860cites workRecombinant respiratory syncytial viruses with deletions in the NS1, NS2, SH, and M2-2 genes are attenuated in vitro and in vivoQ40868890
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CD8 T cells inhibit respiratory syncytial virus (RSV) vaccine-enhanced disease.Q45399869
Induction of balanced immunity in BALB/c mice by vaccination with a recombinant fusion protein containing a respiratory syncytial virus G protein fragment and a CTL epitopeQ45423911
Co-immunization of BALB/c mice with recombinant immunogens containing G protein fragment and chimeric CTL epitope of respiratory syncytial virus induces enhanced cellular immunity and high level of antibody responseQ45453606
Enhanced pulmonary immunopathology following neonatal priming with formalin-inactivated respiratory syncytial virus but not with the BBG2NA vaccine candidateQ45723621
Immune responses to the nonglycosylated ectodomain of respiratory syncytial virus attachment glycoprotein mediate pulmonary eosinophilia in inbred strains of mice with different MHC haplotypesQ45725679
Virus clearance and immunopathology by CD8(+) T cells during infection with respiratory syncytial virus are mediated by IFN-gammaQ45731094
Safety and immunogenicity of a purified F protein respiratory syncytial virus (PFP-2) vaccine in seropositive children with bronchopulmonary dysplasiaQ45757916
[RSV infection course in infants and young children during hospitalization]Q84079746
The attachment (G) glycoprotein of respiratory syncytial virus contains a single immunodominant epitope that elicits both Th1 and Th2 CD4+ T cell responses.Q30306426
The number of respiratory syncytial virus (RSV)-specific memory CD8 T cells in the lung is critical for their ability to inhibit RSV vaccine-enhanced pulmonary eosinophilia.Q30437797
Virus-specific CD8+ T lymphocytes downregulate T helper cell type 2 cytokine secretion and pulmonary eosinophilia during experimental murine respiratory syncytial virus infectionQ30442832
Recombinant respiratory syncytial virus bearing a deletion of either the NS2 or SH gene is attenuated in chimpanzees.Q33645414
Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in gene expression and provides a capability for vaQ33707803
Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutantQ33738521
Genetic variability of respiratory syncytial viruses (RSV) prevalent in Southwestern China from 2006 to 2009: emergence of subgroup B and A RSV as dominant strainsQ33769665
Priming with secreted glycoprotein G of respiratory syncytial virus (RSV) augments interleukin-5 production and tissue eosinophilia after RSV challengeQ33783066
The cysteine-rich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxinQ33863111
Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsivenessQ33883942
Respiratory syncytial virus (RSV) G glycoprotein is not necessary for vaccine-enhanced disease induced by immunization with formalin-inactivated RSV.Q34151000
Respiratory syncytial virus infection in elderly and high-risk adultsQ34414401
Human Respiratory Syncytial Virus in Children with Acute Respiratory Tract Infections in ChinaQ34489610
The cysteine-rich region and secreted form of the attachment G glycoprotein of respiratory syncytial virus enhance the cytotoxic T-lymphocyte response despite lacking major histocompatibility complex class I-restricted epitopesQ34651258
Contribution of respiratory syncytial virus G antigenicity to vaccine-enhanced illness and the implications for severe disease during primary respiratory syncytial virus infectionQ35632362
The future of respiratory syncytial virus vaccine developmentQ35632372
Generation of atypical pulmonary inflammatory responses in BALB/c mice after immunization with the native attachment (G) glycoprotein of respiratory syncytial virusQ35872191
New generation live vaccines against human respiratory syncytial virus designed by reverse geneticsQ36237057
Increased genetic and phenotypic stability of a promising live-attenuated respiratory syncytial virus vaccine candidate by reverse geneticsQ36276526
Characterization of recombinant respiratory syncytial viruses with the region responsible for type 2 T-cell responses and pulmonary eosinophilia deleted from the attachment (G) protein.Q36684360
Understanding respiratory syncytial virus (RSV) vaccine-enhanced disease.Q36961083
The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenuated, respiratory syncytial virus vaccinesQ37384009
Strategic priorities for respiratory syncytial virus (RSV) vaccine developmentQ37572640
Current progress on development of respiratory syncytial virus vaccine.Q37869553
Whole genome characterization of non-tissue culture adapted HRSV strains in severely infected childrenQ38305707
A stabilized respiratory syncytial virus reverse genetics system amenable to recombination-mediated mutagenesisQ39260328
Respiratory syncytial virus that lacks open reading frame 2 of the M2 gene (M2-2) has altered growth characteristics and is attenuated in rodentsQ39588511
Functional analysis of recombinant respiratory syncytial virus deletion mutants lacking the small hydrophobic and/or attachment glycoprotein geneQ39603697
A highly attenuated recombinant human respiratory syncytial virus lacking the G protein induces long-lasting protection in cotton ratsQ39696619
Safety and immunogenicity of respiratory syncytial virus purified fusion protein-2 vaccine in pregnant womenQ40555244
Rescue of bovine respiratory syncytial virus from cloned cDNA: entire genome sequence of BRSV strain A51908.Q40766426
P304page(s)142
P577publication date2014-08-08
P1433published inVirology JournalQ7934868
P1476titleDevelopment of a reverse genetics system for respiratory syncytial virus long strain and an immunogenicity study of the recombinant virus
P478volume11

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cites work (P2860)
Q92219117A Contemporary View of Respiratory Syncytial Virus (RSV) Biology and Strain-Specific Differences
Q64938927A Reverse Genetics System for Cypovirus Based on a Bacmid Expressing T7 RNA Polymerase.
Q89860924Engineering of Live Chimeric Vaccines against Human Metapneumovirus
Q26795706Rift Valley fever virus: A review of diagnosis and vaccination, and implications for emergence in Europe
Q64252092The One Health Approach is Necessary for the Control of Rift Valley Fever Infections in Egypt: A Comprehensive Review

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