The cysteine-rich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxin

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The cysteine-rich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxin is …
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scholarly articleQ13442814

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P819ADS bibcode2005PNAS..102.8996P
P356DOI10.1073/PNAS.0409478102
P932PMC publication ID1157014
P698PubMed publication ID15956195
P5875ResearchGate publication ID7787036

P50authorJosé A. MeleroQ41481214
Ruth A KarronQ92344448
P2093author name stringR Michael Hendry
Pablo M Irusta
Peter L Collins
Fernando P Polack
Steven R Kleeberger
Guillermina A Melendi
Bhagvanji Thumar
Scott J Hoffman
Federico R Laham
M Florencia Delgado
M Paula Schiatti
P2860cites workSIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signalingQ24316441
Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxinQ28306447
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infectionQ28509078
Modulation of Th1 activation and inflammation by the NF-kappaB repressor Foxj1Q28586535
Environmental exposure to endotoxin and its relation to asthma in school-age childrenQ29614294
Toll-like receptors and innate immunityQ29615458
Visualization and characterization of respiratory syncytial virus F-specific CD8(+) T cells during experimental virus infectionQ30308018
Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivationQ33708904
Respiratory syncytial virus G and/or SH glycoproteins modify CC and CXC chemokine mRNA expression in the BALB/c mouseQ33807265
Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virusQ33848810
Respiratory syncytial virus (RSV) G glycoprotein is not necessary for vaccine-enhanced disease induced by immunization with formalin-inactivated RSV.Q34151000
The G glycoprotein of human respiratory syncytial viruses of subgroups A and B: extensive sequence divergence between antigenically related proteinsQ34337480
The central conserved cystine noose of the attachment G protein of human respiratory syncytial virus is not required for efficient viral infection in vitro or in vivoQ34340452
Association of respiratory syncytial virus bronchiolitis with the interleukin 8 gene region in UK familiesQ35533594
A role for immune complexes in enhanced respiratory syncytial virus diseaseQ36371267
Cytolytic T-lymphocyte responses to respiratory syncytial virus: effector cell phenotype and target proteins.Q36782773
Immunity and immunopathology to respiratory syncytial virus. The mouse modelQ40408360
Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseasesQ40528753
IL-13 is sufficient for respiratory syncytial virus G glycoprotein-induced eosinophilia after respiratory syncytial virus challengeQ40671941
Contribution of the respiratory syncytial virus G glycoprotein and its secreted and membrane-bound forms to virus replication in vitro and in vivoQ40771213
Different patterns of cytokine induction in cultures of respiratory syncytial (RS) virus-specific human TH cell lines following stimulation with RS virus and RS virus proteinsQ41187648
Loss of conserved cysteine residues in the attachment (G) glycoprotein of two human respiratory syncytial virus escape mutants that contain multiple A-G substitutions (hypermutations).Q42673660
CX3C chemokine mimicry by respiratory syncytial virus G glycoproteinQ43690717
Respiratory syncytial virus deficient in soluble G protein induced an increased proinflammatory response in human lung epithelial cellsQ44237000
Prolonged production of TNF-alpha exacerbates illness during respiratory syncytial virus infectionQ45598082
Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus diseaseQ45640302
Respiratory syncytial virus-induced activation of nuclear factor-kappaB in the lung involves alveolar macrophages and toll-like receptor 4-dependent pathwaysQ45730326
Adaptive immune responses of patients with asthma to the attachment (G) glycoprotein of respiratory synctial virusQ45734212
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virusQ45739890
Structural homology of the central conserved region of the attachment protein G of respiratory syncytial virus with the fourth subdomain of 55-kDa tumor necrosis factor receptor.Q45756429
Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gram-negative infectionsQ78439420
P433issue25
P407language of work or nameEnglishQ1860
P921main subjectendotoxinsQ319997
respiratory syncytial virusQ1052913
modulation by virus of host processQ14818042
RSV major surface glycoprotein GQ24784703
P304page(s)8996-9001
P577publication date2005-06-14
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleThe cysteine-rich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxin
P478volume102

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