Viral and host factors in human respiratory syncytial virus pathogenesis

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Viral and host factors in human respiratory syncytial virus pathogenesis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1128/JVI.01625-07
P932PMC publication ID2258918
P698PubMed publication ID17928346

P50authorBarney S. GrahamQ89108863
P2093author name stringPeter L Collins
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Role of the M2-1 transcription antitermination protein of respiratory syncytial virus in sequential transcription.Q33815697
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Respiratory syncytial virus (RSV) G glycoprotein is not necessary for vaccine-enhanced disease induced by immunization with formalin-inactivated RSV.Q34151000
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The central conserved cystine noose of the attachment G protein of human respiratory syncytial virus is not required for efficient viral infection in vitro or in vivoQ34340452
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Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathologyQ34364942
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Respiratory syncytial virus G protein and G protein CX3C motif adversely affect CX3CR1+ T cell responsesQ34486238
The pathogenesis of respiratory syncytial virus disease in childhoodQ34628933
Alpha and lambda interferon together mediate suppression of CD4 T cells induced by respiratory syncytial virusQ34647754
The cysteine-rich region and secreted form of the attachment G glycoprotein of respiratory syncytial virus enhance the cytotoxic T-lymphocyte response despite lacking major histocompatibility complex class I-restricted epitopesQ34651258
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Differential immune responses and pulmonary pathophysiology are induced by two different strains of respiratory syncytial virusQ35222083
Bronchoalveolar lavage cellularity in infants with severe respiratory syncytial virus bronchiolitis.Q35274231
Effectiveness of drug therapies to treat or prevent respiratory syncytial virus infection-related morbidityQ35548189
Review of epidemiology and clinical risk factors for severe respiratory syncytial virus (RSV) infectionQ35582849
The M2-2 protein of human respiratory syncytial virus is a regulatory factor involved in the balance between RNA replication and transcriptionQ35645905
Respiratory syncytial virus induces interleukin-10 by human alveolar macrophages. Suppression of early cytokine production and implications for incomplete immunityQ35766589
Inhibition of airway Na+ transport by respiratory syncytial virusQ35785372
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Identification of a novel virulence factor in recombinant pneumonia virus of miceQ35948067
Effects of viral respiratory infections on lung development and childhood asthmaQ36086948
Heterogeneity of the association between lower respiratory illness in infancy and subsequent asthmaQ36237054
New generation live vaccines against human respiratory syncytial virus designed by reverse geneticsQ36237057
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Age at first viral infection determines the pattern of T cell-mediated disease during reinfection in adulthoodQ36371040
A role for immune complexes in enhanced respiratory syncytial virus diseaseQ36371267
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Casein kinase 2-mediated phosphorylation of respiratory syncytial virus phosphoprotein P is essential for the transcription elongation activity of the viral polymerase; phosphorylation by casein kinase 1 occurs mainly at Ser(215) and is without effeQ39595915
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The membrane-associated and secreted forms of the respiratory syncytial virus attachment glycoprotein G are synthesized from alternative initiation codonsQ40038247
Cellular response to respiratory viruses with particular reference to children with disorders of cell-mediated immunityQ40119503
Coupled translation of the second open reading frame of M2 mRNA is sequence dependent and differs significantly within the subfamily Pneumovirinae.Q40128662
Interferon production in children with respiratory syncytial, influenza, and parainfluenza virus infectionsQ40146611
Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligaseQ40179439
Nonstructural proteins of respiratory syncytial virus suppress premature apoptosis by an NF-kappaB-dependent, interferon-independent mechanism and facilitate virus growthQ40199774
Retinoic acid-inducible gene I mediates early antiviral response and Toll-like receptor 3 expression in respiratory syncytial virus-infected airway epithelial cellsQ40208138
The transmission dynamics of groups A and B human respiratory syncytial virus (hRSV) in England & Wales and Finland: seasonality and cross-protection.Q40432320
Respiratory syncytial virus infections in previously healthy working adultsQ40597674
Respiratory syncytial virus up-regulates TLR4 and sensitizes airway epithelial cells to endotoxin.Q40625076
Natural reinfection with respiratory syncytial virus does not boost virus-specific T-cell immunityQ40708973
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Passively acquired antibodies suppress humoral but not cell-mediated immunity in mice immunized with live attenuated respiratory syncytial virus vaccinesQ40779398
Respiratory syncytial virus infection in adults: clinical, virologic, and serial pulmonary function studiesQ40877469
Respiratory syncytical virus-induced chemokine expression in the lower airways: eosinophil recruitment and degranulationQ40951359
Evaluation of two live, cold-passaged, temperature-sensitive respiratory syncytial virus vaccines in chimpanzees and in human adults, infants, and childrenQ41077230
Experimental respiratory syncytial virus infection of four species of primatesQ41378865
Membrane orientation and oligomerization of the small hydrophobic protein of human respiratory syncytial virusQ41544670
Antigenic structure, evolution and immunobiology of human respiratory syncytial virus attachment (G) proteinQ41625980
Differential response of dendritic cells to human metapneumovirus and respiratory syncytial virusQ42106072
Inhibition of toll-like receptor 7- and 9-mediated alpha/beta interferon production in human plasmacytoid dendritic cells by respiratory syncytial virus and measles virusQ42723106
Modeling the structure of the respiratory syncytial virus small hydrophobic protein by silent-mutation analysis of global searching molecular dynamicsQ43205497
A comparison of cytokine responses in respiratory syncytial virus and influenza A infections in infantsQ43479188
Cell-mediated Immunity to Respiratory Syncytial Virus Induced by Inactivated Vaccine or by InfectionQ43672387
CX3C chemokine mimicry by respiratory syncytial virus G glycoproteinQ43690717
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectpathogenesisQ372016
respiratory syncytial virusQ1052913
modulation by virus of host processQ14818042
modulation by host of viral processQ22244941
P304page(s)2040-2055
P577publication date2007-10-10
P1433published inJournal of VirologyQ1251128
P1476titleViral and host factors in human respiratory syncytial virus pathogenesis
P478volume82

Reverse relations

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Q36878963Investigating the Influence of Ribavirin on Human Respiratory Syncytial Virus RNA Synthesis by Using a High-Resolution Transcriptome Sequencing Approach
Q35862041Kinetics of Respiratory Syncytial Virus (RSV) Memphis Strain 37 (M37) Infection in the Respiratory Tract of Newborn Lambs as an RSV Infection Model for Human Infants
Q93105055Lack of Activation Marker Induction and Chemokine Receptor Switch in Human Neonatal Myeloid Dendritic Cells in Response to Human Respiratory Syncytial Virus
Q26830726Lamb model of respiratory syncytial virus-associated lung disease: insights to pathogenesis and novel treatments
Q33812212Live attenuated B. pertussis BPZE1 rescues the immune functions of Respiratory Syncytial virus infected human dendritic cells by promoting Th1/Th17 responses
Q39794677Local evolutionary patterns of human respiratory syncytial virus derived from whole-genome sequencing
Q33951970Low CCR7-mediated migration of human monocyte derived dendritic cells in response to human respiratory syncytial virus and human metapneumovirus
Q47238680Memory CD8 T cells mediate severe immunopathology following respiratory syncytial virus infection.
Q34059404Modification of the respiratory syncytial virus f protein in virus-like particles impacts generation of B cell memory
Q40061831Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity
Q27022693Modulation of host adaptive immunity by hRSV proteins
Q34755309Molecular epidemiology and phylodynamics of the human respiratory syncytial virus fusion protein in northern Taiwan
Q35831296Multiple CD4+ T cell subsets produce immunomodulatory IL-10 during respiratory syncytial virus infection
Q35826605Natural killer cells are involved in acute lung immune injury caused by respiratory syncytial virus infection
Q92266520Neutrophil recruitment and activation are differentially dependent on MyD88/TRIF and MAVS signaling during RSV infection
Q28115807New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein
Q33558475Newcastle disease virus-like particles containing respiratory syncytial virus G protein induced protection in BALB/c mice, with no evidence of immunopathology
Q36845814Nonstructural proteins 1 and 2 of respiratory syncytial virus suppress maturation of human dendritic cells
Q30385012Novel insights into human respiratory syncytial virus-host factor interactions through integrated proteomics and transcriptomics analysis
Q52574400Osteopontin plays a pivotal role in increasing severity of respiratory syncytial virus infection.
Q41923937Oxysophocarpine inhibits lung injury induced by respiratory syncytial virus
Q92578314PD-1 of Sigmodon hispidus: Gene identification, characterization and preliminary evaluation of expression in inactivated RSV vaccine-induced enhanced respiratory disease
Q35535626Palivizumab epitope-displaying virus-like particles protect rodents from RSV challenge
Q37002647Phosphatidylglycerol provides short-term prophylaxis against respiratory syncytial virus infection
Q92527882Plasmacytoid Dendritic Cells Contribute to the Production of IFN-β via TLR7-MyD88-Dependent Pathway and CTL Priming during Respiratory Syncytial Virus Infection
Q34502529Postnatal Infections and Immunology Affecting Chronic Lung Disease of Prematurity
Q58110816Postviral atopic airway disease: pathogenesis and potential avenues for intervention
Q98735527Prefusion RSV F Immunization Elicits Th2-Mediated Lung Pathology in Mice When Formulated With a Th2 (but Not a Th1/Th2-Balanced) Adjuvant Despite Complete Viral Protection
Q37841269Prevention of serious respiratory syncytial virus-related illness. I: Disease pathogenesis and early attempts at prevention
Q33813095Primary human mDC1, mDC2, and pDC dendritic cells are differentially infected and activated by respiratory syncytial virus
Q35566601Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years
Q38671927Prolonged viral replication and longitudinal viral dynamic differences among respiratory syncytial virus (RSV) infected infants.
Q37721415Prospects for defined epitope vaccines for respiratory syncytial virus
Q36739674Protection against respiratory syncytial virus by inactivated influenza virus carrying a fusion protein neutralizing epitope in a chimeric hemagglutinin
Q34542687Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein
Q34320755Quantitative proteomic analysis of A549 cells infected with human respiratory syncytial virus
Q39626990Quantitative proteomic analysis of A549 cells infected with human respiratory syncytial virus subgroup B using SILAC coupled to LC-MS/MS.
Q42215606Rapid replacement of human respiratory syncytial virus A with the ON1 genotype having 72 nucleotide duplication in G gene
Q34261898Rational design of human metapneumovirus live attenuated vaccine candidates by inhibiting viral mRNA cap methyltransferase
Q37412509Recent advances in diagnosis, prevention, and treatment of human respiratory syncytial virus.
Q38617302Recent advances in the development of subunit-based RSV vaccines.
Q33840252Reduced Dicer expression in the cord blood of infants admitted with severe respiratory syncytial virus disease
Q39629562Reduced innate immune response, apoptosis, and virus release in cells cured of respiratory syncytial virus persistent infection.
Q37053256Regulation of STAT signaling in mouse bone marrow derived dendritic cells by respiratory syncytial virus.
Q35765491Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection.
Q37252618Regulatory T cells prevent Th2 immune responses and pulmonary eosinophilia during respiratory syncytial virus infection in mice
Q37127882Regulatory T cells promote early influx of CD8+ T cells in the lungs of respiratory syncytial virus-infected mice and diminish immunodominance disparities
Q58780345Removal of the N-Glycosylation Sequon at Position N116 Located in p27 of the Respiratory Syncytial Virus Fusion Protein Elicits Enhanced Antibody Responses after DNA Immunization
Q40760956Respiratory Syncytial Virus (RSV) Pulmonary Infection in Humanized Mice Induces Human Anti-RSV Immune Responses and Pathology
Q59358484Respiratory Syncytial Virus Hospitalizations among U.S. Preterm Infants Compared with Term Infants Before and After the 2014 American Academy of Pediatrics Guidance on Immunoprophylaxis: 2012-2016
Q103825959Respiratory Syncytial Virus Infection Reduces Kynurenic Acid Production and Reverses Th17/Treg Balance by Modulating Indoleamine 2,3-Dioxygenase (IDO) Molecules in Plasmacytoid Dendritic Cells
Q41232947Respiratory Syncytial Virus Infection Upregulates NLRC5 and Major Histocompatibility Complex Class I Expression through RIG-I Induction in Airway Epithelial Cells
Q90280265Respiratory Syncytial Virus Prophylaxis in Infants With Congenital Diaphragmatic Hernia in the Canadian Respiratory Syncytial Virus Evaluation Study of Palivizumab, 2005-2017
Q26748983Respiratory Syncytial Virus and Cellular Stress Responses: Impact on Replication and Physiopathology
Q36151400Respiratory Syncytial Virus-Infected Mesenchymal Stem Cells Regulate Immunity via Interferon Beta and Indoleamine-2,3-Dioxygenase
Q38694691Respiratory syncytial virus (RSV) entry is inhibited by serine protease inhibitor AEBSF when present during an early stage of infection.
Q28540852Respiratory syncytial virus can infect basal cells and alter human airway epithelial differentiation
Q91361642Respiratory syncytial virus entry and how to block it
Q42978263Respiratory syncytial virus genotypes NA1, ON1, and BA9 are prevalent in Thailand, 2012-2015.
Q30425776Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2.
Q39525784Respiratory syncytial virus hospitalization outcomes and costs of full-term and preterm infants
Q37239031Respiratory syncytial virus infection activates IL-13-producing group 2 innate lymphoid cells through thymic stromal lymphopoietin
Q40054901Respiratory syncytial virus infection of newborn CX3CR1-deficient mice induces a pathogenic pulmonary innate immune response
Q39897567Respiratory syncytial virus inhibits lung epithelial Na+ channels by up-regulating inducible nitric-oxide synthase.
Q33886159Respiratory syncytial virus interferon antagonist NS1 protein suppresses and skews the human T lymphocyte response
Q38076133Respiratory syncytial virus persistence in macrophages alters the profile of cellular gene expression
Q36946801Respiratory syncytial virus persistence in the lungs correlates with airway hyperreactivity in the mouse model
Q56893551Respiratory syncytial virus vaccine development
Q84854616Respiratory syncytial virus vaccine development
Q38098094Respiratory syncytial virus--a comprehensive review
Q57798434Respiratory syncytial virus-associated seizures in Korean children, 2011-2016.
Q38656562Respiratory syncytial virus: a systematic scientometric analysis of the global publication output and the gender distribution of publishing authors
Q38079432Respiratory syncytial virus: current progress in vaccine development
Q33591243Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology
Q36672339Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand
Q36650501Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome
Q40749296Robust Cytokine and Chemokine Response in Nasopharyngeal Secretions: Association With Decreased Severity in Children With Physician Diagnosed Bronchiolitis
Q34175747Robust IgA and IgG-producing antibody forming cells in the diffuse-NALT and lungs of Sendai virus-vaccinated cotton rats associate with rapid protection against human parainfluenza virus-type 1
Q34271670Roles of the respiratory syncytial virus trailer region: effects of mutations on genome production and stress granule formation
Q42173061Scop3D: three-dimensional visualization of sequence conservation
Q35667184Sendai virus-based RSV vaccine protects African green monkeys from RSV infection
Q33724997Sendai virus-based RSV vaccine protects against RSV challenge in an in vivo maternal antibody model
Q59794692Sequence Analysis of the Fusion Protein Gene of Human Respiratory Syncytial Virus Circulating in China from 2003 to 2014
Q30834597Single- and multiple viral respiratory infections in children: disease and management cannot be related to a specific pathogen
Q58566365State of the Art in Respiratory Syncytial Virus Drug Discovery and Development
Q116166980Structural basis for IFN antagonism by human respiratory syncytial virus nonstructural protein 2
Q37174419Suppression of IRG-1 Reduces Inflammatory Cell Infiltration and Lung Injury in Respiratory Syncytial Virus Infection by Reducing Production of Reactive Oxygen Species
Q89842506Suspension microarray-based comparison of oropharyngeal swab and bronchoalveolar lavage fluid for pathogen identification in young children hospitalized with respiratory tract infection
Q40309226Systematic Analysis of Cell-Type Differences in the Epithelial Secretome Reveals Insights into the Pathogenesis of Respiratory Syncytial Virus-Induced Lower Respiratory Tract Infections
Q28395374T cell-mediated host immune defenses in the lung
Q59358485T-Cell Responses in Adults During Natural Respiratory Syncytial Virus Infection
Q35101883The Role of RSV Infection in Asthma Initiation and Progression: Findings in a Mouse Model
Q33887779The Thr205 phosphorylation site within respiratory syncytial virus matrix (M) protein modulates M oligomerization and virus production
Q33535780The chemokine MIP1alpha/CCL3 determines pathology in primary RSV infection by regulating the balance of T cell populations in the murine lung.
Q36163501The human respiratory syncytial virus nonstructural protein 1 regulates type I and type II interferon pathways
Q40522232The innate immune response to RSV: Advances in our understanding of critical viral and host factors.
Q28728377The interactome of the human respiratory syncytial virus NS1 protein highlights multiple effects on host cell biology
Q40933366The preventive effect of vaccine prophylaxis on severe respiratory syncytial virus infection: A meta-analysis.
Q37585325The regulation of type I interferon production by paramyxoviruses.
Q58611829The resistance against Trichinella spiralis infection induced by primary infection with respiratory syncytial virus
Q41511965The respiratory syncytial virus fusion protein formulated with a novel combination adjuvant induces balanced immune responses in lambs with maternal antibodies
Q59358526The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates
Q64286426The viral protein corona directs viral pathogenesis and amyloid aggregation
Q36947774Tiotropium Attenuates Virus-Induced Pulmonary Inflammation in Cigarette Smoke-Exposed Mice
Q57174671Topology and cellular localization of the small hydrophobic protein of avian metapneumovirus
Q40104785Transient Depletion of CD169+ Cells Contributes to Impaired Early Protection and Effector CD8+ T Cell Recruitment against Mucosal Respiratory Syncytial Virus Infection
Q38140040Translational sciences approach to RSV vaccine development
Q59356158Type I Interferon Potentiates IgA Immunity to Respiratory Syncytial Virus Infection During Infancy
Q64229661Utility of the Neonatal Calf Model for Testing Vaccines and Intervention Strategies for Use against Human RSV Infection
Q28071857Viral Infection in the Development and Progression of Pediatric Acute Respiratory Distress Syndrome
Q90617438Viral N6-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus
Q37788451Viral pneumonias in immunocompromised adult hosts
Q36723340Viral shedding and immune responses to respiratory syncytial virus infection in older adults
Q37996242Virus entry: old viruses, new receptors
Q34791209Virus-like nanoparticle and DNA vaccination confers protection against respiratory syncytial virus by modulating innate and adaptive immune cells
Q40409972Virus-like particle vaccine by intranasal vaccination elicits protective immunity against respiratory syncytial viral infection in mice
Q49187990Viruslike Particles Encapsidating Respiratory Syncytial Virus M and M2 Proteins Induce Robust T Cell Responses.
Q36559764p38 and OGT sequestration into viral inclusion bodies in cells infected with human respiratory syncytial virus suppresses MK2 activities and stress granule assembly
Q64129570siRNA-Mediated Simultaneous Regulation of the Cellular Innate Immune Response and Human Respiratory Syncytial Virus Replication.

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