Intranasal immunization with a single dose of the fusion protein formulated with a combination adjuvant induces long-term protective immunity against respiratory syncytial virus

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Intranasal immunization with a single dose of the fusion protein formulated with a combination adjuvant induces long-term protective immunity against respiratory syncytial virus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/21645515.2017.1349584
P8608Fatcat IDrelease_nqz5fiwsrffajfehoajumbxfiy
P932PMC publication ID5718833
P698PubMed publication ID28825870

P50authorRavendra GargQ83904749
P2093author name stringS van Drunen Littel-van den Hurk
A Potter
L Latimer
V Gerdts
P2860cites workIntranasal immunization of mice with a formalin-inactivated bovine respiratory syncytial virus vaccine co-formulated with CpG oligodeoxynucleotides and polyphosphazenes results in enhanced protectionQ45398592
Human infant respiratory syncytial virus (RSV)-specific type 1 and 2 cytokine responses ex vivo during primary RSV infectionQ45404243
Shifting immunodominance pattern of two cytotoxic T-lymphocyte epitopes in the F glycoprotein of the Long strain of respiratory syncytial virusQ45564955
Determinants of susceptibility to challenge and the antibody response of adult volunteers given experimental respiratory syncytial virus vaccinesQ45849052
Comparison of the ability of formalin-inactivated respiratory syncytial virus, immunopurified F, G and N proteins and cell lysate to enhance pulmonary changes in Balb/c miceQ45868048
The novel adjuvant combination of CpG ODN, indolicidin and polyphosphazene induces potent antibody- and cell-mediated immune responses in mice.Q46018304
Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants. The IMpact-RSV Study GroupQ77300551
A novel respiratory syncytial virus (RSV) F subunit vaccine adjuvanted with GLA-SE elicits robust protective TH1-type humoral and cellular immunity in rodent modelsQ27312129
Antimicrobial and host-defense peptides as new anti-infective therapeutic strategiesQ29617810
Antigen persistence and the control of local T cell memory by migrant respiratory dendritic cells after acute virus infectionQ30433900
Polyphosphazene polyelectrolytes: a link between the formation of noncovalent complexes with antigenic proteins and immunostimulating activity.Q31170493
Activation of interferon response through toll-like receptor 3 impacts viral pathogenesis and pulmonary toll-like receptor expression during respiratory syncytial virus and influenza infections in the cotton rat Sigmodon hispidus modelQ33901537
Respiratory syncytial virus and parainfluenza virusQ33952428
Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccineQ34206177
Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus diseaseQ34330690
Respiratory syncytial virus infection in elderly and high-risk adultsQ34414401
Biological challenges and technological opportunities for respiratory syncytial virus vaccine developmentQ34504791
Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.Q34624625
Immunological mechanisms of vaccinationQ35659533
CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cellsQ35971414
Long-term and memory immune responses in mice against Newcastle disease virus-like particles containing respiratory syncytial virus glycoprotein ectodomainsQ36363325
Viral and host factors in human respiratory syncytial virus pathogenesisQ36483836
Respiratory syncytial virus (RSV) vaccines--two steps back for one leap forward.Q37110057
Long-term activation of TLR3 by poly(I:C) induces inflammation and impairs lung function in miceQ37222041
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvantQ37273249
Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization.Q37404708
A recombinant anchorless respiratory syncytial virus (RSV) fusion (F) protein/monophosphoryl lipid A (MPL) vaccine protects against RSV-induced replication and lung pathology.Q37627348
Multifunctional cationic host defence peptides and their clinical applicationsQ37875767
Enhanced immune responses and protection by vaccination with respiratory syncytial virus fusion protein formulated with CpG oligodeoxynucleotide and innate defense regulator peptide in polyphosphazene microparticles.Q39328333
Immunomodulatory activities of small host defense peptidesQ40430371
A single intranasal immunization with a subunit vaccine formulation induces higher mucosal IgA production than live respiratory syncytial virusQ40512544
The respiratory syncytial virus fusion protein formulated with a novel combination adjuvant induces balanced immune responses in lambs with maternal antibodiesQ41511965
Vaccination with the RSV fusion protein formulated with a combination adjuvant induces long-lasting protective immunity.Q42235080
Induction of mucosal immunity and protection by intranasal immunization with a respiratory syncytial virus subunit vaccine formulation.Q42261596
Intranasal IFN-gamma gene transfer protects BALB/c mice against respiratory syncytial virus infectionQ44390775
Double-stranded RNA induces similar pulmonary dysfunction to respiratory syncytial virus in BALB/c miceQ45367510
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 4.0 InternationalQ24082749
P6216copyright statuscopyrightedQ50423863
P433issue12
P304page(s)2894-2901
P577publication date2017-08-21
P1433published inHuman Vaccines & ImmunotherapeuticsQ21072749
P1476titleIntranasal immunization with a single dose of the fusion protein formulated with a combination adjuvant induces long-term protective immunity against respiratory syncytial virus
P478volume13

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cites work (P2860)
Q91440678A lipidic delivery system of a triple vaccine adjuvant enhances mucosal immunity following nasal administration in mice
Q47137438Design and evaluation of the immunogenicity and efficacy of a biomimetic particulate formulation of viral antigens
Q55534670Respiratory Syncytial Virus Vaccine Approaches: a Current Overview.

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