1,25-Dihydroxyvitamin D3 suppresses TLR8 expression and TLR8-mediated inflammatory responses in monocytes in vitro and experimental autoimmune encephalomyelitis in vivo

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1,25-Dihydroxyvitamin D3 suppresses TLR8 expression and TLR8-mediated inflammatory responses in monocytes in vitro and experimental autoimmune encephalomyelitis in vivo is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...858808L
P356DOI10.1371/JOURNAL.PONE.0058808
P932PMC publication ID3597563
P698PubMed publication ID23516559
P5875ResearchGate publication ID235959671

P2093author name stringBo Li
K-H William Lau
Michael H Walter
David J Baylink
Weirong Xing
Xuezhong Qin
Chandra Deb
Claudia Zannetti
Fatima Rajaallah
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1,25-Dihydroxyvitamin D3 inhibits the differentiation and migration of T(H)17 cells to protect against experimental autoimmune encephalomyelitisQ28475567
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Altered M1/M2 activation patterns of monocytes in severe relapsing experimental rat model of multiple sclerosis. Amelioration of clinical status by M2 activated monocyte administration.Q50695778
1,25-Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyelitis.Q52607615
Influence of 1,25-dihydroxy vitamin D3 on TLR4-induced activation of antigen presenting cells is dependent on the order of receptor engagementQ84000892
Initiation and progression of axonopathy in experimental autoimmune encephalomyelitisQ34344447
Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potentialQ34510368
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1,25-dihydroxyvitamin D(3) ameliorates Th17 autoimmunity via transcriptional modulation of interleukin-17A.Q35192119
Toll-like receptors in cerebral ischemic inflammatory injuryQ35416110
A pilot study of oral calcitriol (1,25-dihydroxyvitamin D3) for relapsing-remitting multiple sclerosisQ35489860
Toll-like receptor (TLR) and inflammasome actions in the central nervous systemQ36058919
Toll-like receptors, endogenous ligands, and systemic autoimmune disease.Q36079856
Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosisQ36119099
Enhancement of 1,25-dihydroxyvitamin D3-mediated suppression of experimental autoimmune encephalomyelitis by calcitoninQ37146841
Toll-like receptor signaling in endogenous neuroprotection and strokeQ37171364
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Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of immunomodulatory treatment strategiesQ37771933
Toll-like receptors expression and signaling in glia cells in neuro-amyloidogenic diseases: towards future therapeutic applicationQ37779740
Animal Models of MS Reveal Multiple Roles of Microglia in Disease PathogenesisQ37971896
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Cutting edge: activation of murine TLR8 by a combination of imidazoquinoline immune response modifiers and polyT oligodeoxynucleotidesQ40212635
Vitamin D3 down-regulates intracellular Toll-like receptor 9 expression and Toll-like receptor 9-induced IL-6 production in human monocytesQ43077082
Gene expression analysis suggests that 1,25-dihydroxyvitamin D3 reverses experimental autoimmune encephalomyelitis by stimulating inflammatory cell apoptosisQ44892486
Effects of vitamin D on expression of Toll-like receptors of monocytes from patients with Behcet's diseaseQ46645654
Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns.Q46886748
Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitisQ48249155
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
experimental autoimmune encephalomyelitisQ494066
P304page(s)e58808
P577publication date2013-03-14
P1433published inPLOS OneQ564954
P1476title1,25-Dihydroxyvitamin D3 suppresses TLR8 expression and TLR8-mediated inflammatory responses in monocytes in vitro and experimental autoimmune encephalomyelitis in vivo
P478volume8

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