Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis

scientific journal article

Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/EJI.200737187
P3181OpenCitations bibliographic resource ID1090956
P698PubMed publication ID18203139
P5875ResearchGate publication ID5648692

P50authorOlle KämpeQ42670114
Monica MartaQ48590117
P2093author name stringAsa Andersson
Magnus Isaksson
Anna Lobell
P2860cites workA receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23RQ24297906
TLR signaling pathwaysQ24570127
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Transforming growth factor-beta induces development of the T(H)17 lineageQ28237370
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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cellsQ28296956
IRF-7 is the master regulator of type-I interferon-dependent immune responsesQ28511410
MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarctionQ28581447
TLR4 contributes to disease-inducing mechanisms resulting in central nervous system autoimmune diseaseQ81040935
Activation of the type I interferon system in primary Sjögren's syndrome: a possible etiopathogenic mechanismQ81629331
IL-23 drives a pathogenic T cell population that induces autoimmune inflammationQ29547525
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17Q29547855
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineagesQ29547871
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brainQ29614225
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptorsQ29615065
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated functionQ29617462
Oral tolerance in myelin basic protein T-cell receptor transgenic mice: suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cellsQ33624770
Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosisQ34312767
T- and B-cell responses to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis and multiple sclerosisQ34398673
CpG motifs in bacterial DNA and their immune effectsQ34542287
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.Q34566135
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The role of CD8(+) T cells in multiple sclerosis and its animal modelsQ36107655
Pathogen recognition with Toll-like receptorsQ36159961
TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis.Q36403076
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupusQ36403146
RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.Q36403678
Activation of antigen-presenting cells by microbial products breaks self tolerance and induces autoimmune diseaseQ37221573
MHC haplotype-dependent regulation of MOG-induced EAE in rats.Q37387696
The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsetsQ38356908
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon inductionQ40437839
Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.Q40453661
A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.Q42767100
Suppressive DNA vaccination in myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis involves a T1-biased immune responseQ46451971
Multiple toll-like receptor agonists act as potent adjuvants in the induction of autoimmunityQ46856023
Protective DNA vaccination against experimental autoimmune encephalomyelitis is associated with induction of IFNbetaQ47953576
Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.Q49014751
MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells.Q54705034
Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper functionQ56880717
B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptideQ73170385
TLR2 and TLR4 serve distinct roles in the host immune response against Mycobacterium bovis BCGQ73719168
CpG oligonucleotides are potent adjuvants for the activation of autoreactive encephalitogenic T cells in vivoQ73812186
Nasal administration of multiple antigens suppresses experimental autoimmune myasthenia gravis, encephalomyelitis and neuritisQ74485802
Toll-like receptors control activation of adaptive immune responsesQ74486847
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cellsQ78806915
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectexperimental autoimmune encephalomyelitisQ494066
Myeloid differentiation primary response gene 88Q14905922
Toll-like receptor 4Q14914104
Toll-like receptor 9Q15332574
P304page(s)565–575
P577publication date2008-02-01
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleUnexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis
P478volume38

Reverse relations

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