| scholarly article | Q13442814 |
| P50 | author | Gabriel Nussbaum | Q88438546 |
| P2093 | author name string | Shira Dishon | |
| Dimitrios Karussis | |||
| Amnon Hoffman | |||
| Chaim Gilon | |||
| Ibrahim Kassis | |||
| Joseph Fanous | |||
| Alaa Talhami | |||
| Adi Schumacher | |||
| P2860 | cites work | Structural basis for signal transduction by the Toll/interleukin-1 receptor domains | Q24290524 |
| What the Myddosome structure tells us about the initiation of innate immunity | Q24338472 | ||
| Pyogenic bacterial infections in humans with MyD88 deficiency | Q24653859 | ||
| The TLR and IL-1 signalling network at a glance | Q27013358 | ||
| Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling | Q27655822 | ||
| Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection | Q27672321 | ||
| Structural Insights into TIR Domain Specificity of the Bridging Adaptor Mal in TLR4 Signaling | Q27678387 | ||
| Pathogen recognition and innate immunity | Q27861084 | ||
| Pattern recognition receptors and inflammation | Q27861115 | ||
| The nature of multiple sclerosis | Q28264847 | ||
| Oncogenically active MYD88 mutations in human lymphoma | Q28301648 | ||
| MyD88-, but not Nod1- and/or Nod2-deficient mice, show increased susceptibility to polymicrobial sepsis due to impaired local inflammatory response | Q28512466 | ||
| Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis | Q28591514 | ||
| Recognition of microorganisms and activation of the immune response | Q29617903 | ||
| SUMO fusions and SUMO-specific protease for efficient expression and purification of proteins. | Q30342324 | ||
| Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis | Q30477818 | ||
| The smallest known non-avian theropod dinosaur | Q30621543 | ||
| A dimer of the Toll-like receptor 4 cytoplasmic domain provides a specific scaffold for the recruitment of signalling adaptor proteins | Q33295379 | ||
| MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases | Q33569870 | ||
| The use of small molecule high-throughput screening to identify inhibitors of the proteinase 3-NB1 interaction | Q33574031 | ||
| Inhibition of Myeloid Differentiation Factor 88 Reduces Human and Mouse T-Cell Interleukin-17 and IFNγ Production and Ameliorates Experimental Autoimmune Encephalomyelitis Induced in Mice | Q33734635 | ||
| Backbone cyclic peptide inhibitors of protein kinase B (PKB/Akt). | Q33925861 | ||
| Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosis | Q34312767 | ||
| Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL. | Q34318269 | ||
| MyD88 deficiency results in tissue-specific changes in cytokine induction and inflammation in interleukin-18-independent mice infected with Borrelia burgdorferi | Q34491817 | ||
| Role for MyD88, TLR2 and TLR9 but not TLR1, TLR4 or TLR6 in experimental autoimmune encephalomyelitis. | Q51448540 | ||
| Differential involvement of BB loops of toll-IL-1 resistance (TIR) domain-containing adapter proteins in TLR4- versus TLR2-mediated signal transduction. | Q52564845 | ||
| Cutting Edge: Differential inhibition of TLR signaling pathways by cell-permeable peptides representing BB loops of TLRs. | Q52677025 | ||
| Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II – The Digestion of Trilaurin Protects Desmopressin from Proteolytic Degradation | Q58199031 | ||
| Beta VI turns in peptides and proteins: a model peptide mimicry | Q70618648 | ||
| Simultaneous occlusion of Na+ and phosphate by the intestinal brush border membrane Na+/phosphate cotransporter | Q71219249 | ||
| Interaction of substrates with the intestinal brush border membrane Na/phosphate cotransporter | Q73066806 | ||
| Toll-like receptors control activation of adaptive immune responses | Q74486847 | ||
| Exploring privileged structures: the combinatorial synthesis of cyclic peptides | Q78844334 | ||
| Chemistry of amino acids and peptides | Q79222692 | ||
| Toll-like receptor 2 pathway drives streptococcal cell wall-induced joint inflammation: critical role of myeloid differentiation factor 88 | Q79317498 | ||
| Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound | Q80428452 | ||
| MyD88, IRAK1 and TRAF6 knockdown in human chondrocytes inhibits interleukin-1-induced matrix metalloproteinase-13 gene expression and promoter activity by impairing MAP kinase activation | Q81374082 | ||
| Peptide-mediated interference of TIR domain dimerization in MyD88 inhibits interleukin-1-dependent activation of NF-{kappa}B | Q81497841 | ||
| Converting a peptide into a drug: strategies to improve stability and bioavailability | Q34609303 | ||
| Backbone cyclic helix mimetic of chemokine (C-C motif) receptor 2: a rational approach for inhibiting dimerization of G protein-coupled receptors | Q34739921 | ||
| Cyclic peptides as therapeutic agents and biochemical tools | Q35015231 | ||
| A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses | Q35147460 | ||
| Toll-like receptor signaling | Q35189960 | ||
| Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen | Q36098995 | ||
| Suppression of TLR signaling by targeting TIR domain-containing proteins | Q36676056 | ||
| Pharmacological inhibition of MyD88 homodimerization counteracts renal ischemia reperfusion-induced progressive renal injury in vivo and in vitro | Q36953689 | ||
| Interacting neuroendocrine and innate and acquired immune pathways regulate neutrophil mobilization from bone marrow following hemorrhagic shock | Q37029422 | ||
| A cell biological view of Toll-like receptor function: regulation through compartmentalization. | Q37531879 | ||
| MyD88 is pivotal for the early inflammatory response and subsequent bacterial clearance and survival in a mouse model of Chlamydia pneumoniae pneumonia | Q37864592 | ||
| N-methylation of peptides and proteins: an important element for modulating biological functions | Q38060675 | ||
| Cyclic peptide therapeutics: past, present and future | Q38751909 | ||
| Mutational analysis identifies residues crucial for homodimerization of myeloid differentiation factor 88 (MyD88) and for its function in immune cells. | Q39098027 | ||
| The effect of backbone cyclization on PK/PD properties of bioactive peptide-peptoid hybrids: the melanocortin agonist paradigm. | Q39754683 | ||
| IL-10 mediates resistance to adoptive transfer experimental autoimmune encephalomyelitis in MyD88(-/-) mice | Q39769143 | ||
| Reconstructing the TIR Side of the Myddosome: a Paradigm for TIR-TIR Interactions | Q39997769 | ||
| Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling | Q40113290 | ||
| Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer | Q40163535 | ||
| Peptidases, peptides, and the mammalian blood-brain barrier | Q40878393 | ||
| Structure-Based Design and Synthesis of a Small Molecule that Exhibits Anti-inflammatory Activity by Inhibition of MyD88-mediated Signaling to Bacterial Toxin Exposure | Q41664651 | ||
| MyD88-dependent immune activation mediated by human immunodeficiency virus type 1-encoded Toll-like receptor ligands | Q41877481 | ||
| The type III secretion effector NleE inhibits NF-kappaB activation | Q41893338 | ||
| The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis | Q42853439 | ||
| Can N-methylated amino acids serve as substitutes for prolines in conformational design of cyclic pentapeptides? | Q46263586 | ||
| Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization | Q47864546 | ||
| Small Molecule Analogues of the parasitic worm product ES-62 interact with the TIR domain of MyD88 to inhibit pro-inflammatory signalling | Q48120789 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 9476 | |
| P577 | publication date | 2018-06-21 | |
| P1433 | published in | Scientific Reports | Q2261792 |
| P1476 | title | Development of a Novel Backbone Cyclic Peptide Inhibitor of the Innate Immune TLR/IL1R Signaling Protein MyD88. | |
| P478 | volume | 8 |
Search more.