Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs)

scientific article

Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs) is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2011PNAS..10811542Y
P356DOI10.1073/PNAS.1108535108
P932PMC publication ID3136288
P698PubMed publication ID21709231
P5875ResearchGate publication ID51253702

P50authorKenya HondaQ91045628
Hideki OhdanQ90330341
P2093author name stringTakashi Onoe
Tadatsugu Taniguchi
Hideyuki Yanai
Yukana Nakaima
Tatsuma Ban
Shiho Chiba
P2860cites workA Toll-like receptor recognizes bacterial DNAQ24290668
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune responseQ24317784
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptorsQ27860900
Pathogen recognition and innate immunityQ27861084
Pattern recognition receptors and inflammationQ27861115
Release of chromatin protein HMGB1 by necrotic cells triggers inflammationQ28131815
HMG-1 as a late mediator of endotoxin lethality in miceQ28139166
HMGB1 loves companyQ28243671
HMGB1 and RAGE in inflammation and cancerQ28274621
IRF-7 is the master regulator of type-I interferon-dependent immune responsesQ28511410
HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responsesQ28512353
Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitisQ28591514
Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunityQ29615913
Recognition of microorganisms and activation of the immune responseQ29617903
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGEQ29620722
High-mobility group box 1 and cancerQ33638306
CpG motifs in bacterial DNA trigger direct B-cell activationQ34307394
Innate immunity mediated by TLR9 modulates pathogenicity in an animal model of multiple sclerosisQ34312767
Effects of oligonucleotide length and atomic composition on stimulation of the ATPase activity of translation initiation factor elF4A.Q34362106
Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 bindingQ34647633
Regulation of adaptive immunity by the innate immune systemQ34659642
Plasmacytoid dendritic cells in immunityQ35953140
HMGB1 is a therapeutic target for sterile inflammation and infectionQ35953553
A novel role for HMGB1 in TLR9-mediated inflammatory responses to CpG-DNA.Q35990737
Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease.Q36766872
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapyQ36990578
The role of innate immunity in the induction of autoimmunityQ37245531
A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.Q37394432
Classification, mechanisms of action, and therapeutic applications of inhibitory oligonucleotides for Toll-like receptors (TLR) 7 and 9.Q37758263
Structure of a complex of tandem HMG boxes and DNA.Q38311868
Endotoxin, reticuloendothelial function, and liver injuryQ40320109
TLR9 signals after translocating from the ER to CpG DNA in the lysosomeQ40600429
Human peripheral blood cells differentially recognize and respond to two distinct CPG motifsQ40830636
The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activationQ42525772
Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.Q47368420
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.Q51751254
A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.Q54631516
In vitro inhibition of murine IFN gamma production by phosphorothioate deoxyguanosine oligomersQ72282577
CpG oligonucleotides are potent adjuvants for the activation of autoreactive encephalitogenic T cells in vivoQ73812186
The stabilized structural array of two HMG1/2-boxes endowed by a linker sequence between them is requisite for the effective binding of HMG1 with DNAQ78172405
P433issue28
P407language of work or nameEnglishQ1860
P304page(s)11542-11547
P577publication date2011-06-27
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleSuppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs)
P478volume108

Reverse relations

cites work (P2860)
Q28544993A unique HMG-box domain of mouse Maelstrom binds structured RNA but not double stranded DNA
Q38180799Cytokine networking of innate immunity cells: a potential target of therapy.
Q60959920DNA-Mediated Interferon Signature Induction by SLE Serum Occurs in Monocytes Through Two Pathways: A Mechanism to Inhibit Both Pathways
Q38973776Dynamic localization and the associated translocation mechanism of HMGBs in response to GCRV challenge in CIK cells.
Q37665246Effects of cartilage impact with and without fracture on chondrocyte viability and the release of inflammatory markers.
Q34622835HMGB1 in health and disease
Q37980335HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease
Q24604370High mobility group box protein 1 (HMGB1)-partner molecule complexes enhance cytokine production by signaling through the partner molecule receptor
Q50324081Immunothrombotic Activity of Damage-Associated Molecular Patterns and Extracellular Vesicles in Secondary Organ Failure Induced by Trauma and Sterile Insults
Q28087310Insights into the antiviral immunity against grass carp (Ctenopharyngodon idella) reovirus (GCRV) in grass carp
Q38331503New vistas on TLR9 activation
Q38231610Nucleic acid sensing and beyond: virtues and vices of high-mobility group box 1.
Q53268885Oligodeoxynucleotide inhibition of Toll-like receptors 3, 7, 8, and 9 suppresses cytokine production in a human rheumatoid arthritis model.
Q34169579Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses
Q36189322Regulatory role of suppressive motifs from commensal DNA.
Q38453261Sepsis: a roadmap for future research
Q34050559Sequestering HMGB1 via DNA-conjugated beads ameliorates murine colitis
Q38318293Structure Activity Relationships of α-L-LNA Modified Phosphorothioate Gapmer Antisense Oligonucleotides in Animals
Q27004381Structure-dependent immunostimulatory effect of CpG oligodeoxynucleotides and their delivery system
Q27010345Targeting toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseases
Q38262840The functions of HMGB1 depend on molecular localization and post-translational modifications
Q33732343The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis
Q28067211Toll-like receptors in the pathogenesis of autoimmune diseases: recent and emerging translational developments

Search more.