The Regulation of Th1 Responses by the p38 MAPK

scientific article published on October 11, 2010

The Regulation of Th1 Responses by the p38 MAPK is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4049/JIMMUNOL.1000243
P953full work available at URLhttp://www.jimmunol.org/content/185/10/6205.full.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20937847/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20937847/pdf/?tool=EBI
http://www.jimmunol.org/cgi/content/abstract/185/10/6205
https://europepmc.org/articles/PMC3050061
https://europepmc.org/articles/PMC3050061?pdf=render
https://doi.org/10.4049/jimmunol.1000243
https://journals.aai.org/jimmunol/article-pdf/185/10/6205/1321759/1000243.pdf
P932PMC publication ID3050061
P698PubMed publication ID20937847
P5875ResearchGate publication ID47395645

P2093author name stringXia Zhang
Ziyan Yang
David M. Mosser
Patricia A. Darrah
P2860cites workA Toll-like receptor recognizes bacterial DNAQ24290668
Tristetraprolin (TTP)-14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2a and stabilizes tumor necrosis factor-alpha mRNAQ24336740
Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stabilityQ28508664
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient miceQ28509000
Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decayQ28588318
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesisQ28593865
Interleukin-12 and the regulation of innate resistance and adaptive immunityQ29614602
An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrowQ29615498
Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunityQ29619700
Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathwayQ33888844
Activation of p38 mitogen-activated protein kinase attenuates Leishmania donovani infection in macrophagesQ34130259
Biochemical and functional characterization of three activated macrophage populations.Q34556828
Is MK2 (mitogen-activated protein kinase-activated protein kinase 2) the key for understanding post-transcriptional regulation of gene expression?Q35003449
JNK and p38 MAP kinases in CD4+ and CD8+ T cellsQ35096697
The Ras-MAPK signal transduction pathway, cancer and chromatin remodelingQ36061535
New IL-12-family members: IL-23 and IL-27, cytokines with divergent functionsQ36184396
Recombinant interleukin 12 cures mice infected with Leishmania majorQ36361742
Vaccination with heat-killed leishmania antigen or recombinant leishmanial protein and CpG oligodeoxynucleotides induces long-term memory CD4+ and CD8+ T cell responses and protection against leishmania major infectionQ36369774
MAPKAP kinases - MKs - two's company, three's a crowdQ36371939
Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunityQ36404267
Enhancement of infectious disease vaccines through TLR9-dependent recognition of CpG DNA.Q36627124
IL-12p40: an inherently agonistic cytokineQ36663486
Protein kinases as small molecule inhibitor targets in inflammation.Q36952165
The kinase p38 alpha serves cell type-specific inflammatory functions in skin injury and coordinates pro- and anti-inflammatory gene expressionQ36983159
Activation of the MAPK, ERK, following Leishmania amazonensis infection of macrophagesQ37097916
Dynamic and transient remodeling of the macrophage IL-10 promoter during transcriptionQ37097929
MAPK-activated protein kinase 2 differentially regulates plasmodium falciparum glycosylphosphatidylinositol-induced production of tumor necrosis factor-{alpha} and interleukin-12 in macrophagesQ37257347
Combating tropical infectious diseases: report of the Disease Control Priorities in Developing Countries ProjectQ39078466
Regulation and phenotype of an innate Th1 cell: role of cytokines and the p38 kinase pathwayQ40614085
p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitmentQ43822750
The autoimmune suppressor Gadd45alpha inhibits the T cell alternative p38 activation pathway.Q45286053
Macrophage deletion of p38alpha partially impairs lipopolysaccharide-induced cellular activation.Q46409060
Selective requirement of p38alpha MAPK in cytokine-dependent, but not antigen receptor-dependent, Th1 responses.Q50941847
Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response.Q52520769
Gadd45alpha regulates p38-dependent dendritic cell cytokine production and Th1 differentiation.Q53564713
Murine dendritic cells internalize Leishmania major promastigotes, produce IL-12 p40 and stimulate primary T cell proliferation in vitro.Q54090775
PI3K-mediated negative feedback regulation of IL-12 production in DCsQ74558971
Ability of macrophage subsets to transfer resistance to murine leishmaniasis is dependent on IL-12 productionQ74578829
The p38 mitogen-activated protein kinases can have opposing roles in the antigen-dependent or endotoxin-stimulated production of IL-12 and IFN-gammaQ77357405
Testosterone attenuates p38 MAPK pathway during Leishmania donovani infection of macrophagesQ82881121
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)6205-6213
P577publication date2010-10-11
P1433published inJournal of ImmunologyQ3521441
P1476titleThe regulation of Th1 responses by the p38 MAPK
The Regulation of Th1 Responses by the p38 MAPK
P478volume185

Reverse relations

cites work (P2860)
Q36021357Adjuvants for Leishmania vaccines: from models to clinical application
Q47846903Anti-inflammatory roles of p38α MAPK in macrophages are context dependent and require IL-10.
Q64054989CD28 CD4 T-cell expansions in autoimmune disease suggest a link with cytomegalovirus infection
Q26783488Choice and Design of Adjuvants for Parenteral and Mucosal Vaccines
Q38772655Early Secreted Antigenic Target of 6 kDa of Mycobacterium tuberculosis Stimulates Macrophage Chemoattractant Protein-1 Production by Macrophages and Its Regulation by p38 Mitogen-Activated Protein Kinases and Interleukin-4.
Q39232187Enhanced IL-12p40 production in LPS-stimulated macrophages by inhibiting JNK activation by artemisinin
Q51137509Human Th17 Migration in Three-Dimensional Collagen Involves p38 MAPK.
Q44403427Immunosuppressive effect of silymarin on mitogen-activated protein kinase signalling pathway: the impact on T cell proliferation and cytokine production.
Q33602947Interleukin 17A promotes pneumococcal clearance by recruiting neutrophils and inducing apoptosis through a p38 mitogen-activated protein kinase-dependent mechanism in acute otitis media
Q37727290Leishmania major inhibits IL-12 in macrophages by signalling through CR3 (CD11b/CD18) and down-regulation of ETS-mediated transcription
Q84899471Leukotriene C(4) prevents the complete maturation of murine dendritic cells and modifies interleukin-12/interleukin-23 balance
Q53215488Mincle suppresses Toll-like receptor 4 activation.
Q40396268Mycobacterium indicus pranii (Mw)-mediated protection against visceral leishmaniasis by reciprocal regulation of host dual-specificity phosphatases
Q28830507Neospora caninum Activates p38 MAPK as an Evasion Mechanism against Innate Immunity
Q40962111Peripheral injection of SB203580 inhibits the inflammatory-dependent synthesis of proinflammatory cytokines in the hypothalamus.
Q35213593Platelet activation attracts a subpopulation of effector monocytes to sites of Leishmania major infection
Q59360019Porcine Circovirus Type 2 Suppresses IL-12p40 Induction via Capsid/gC1qR-Mediated MicroRNAs and Signalings
Q39356843Porcine reproductive and respiratory syndrome virus (PRRSV) induces IL-12p40 production through JNK-AP-1 and NF-κB signaling pathways
Q54512826Post-transcriptional regulation of VEGF-A mRNA levels by mitogen-activated protein kinases (MAPKs) during metabolic stress associated with ischaemia/reperfusion.
Q34979258Sm16, a major component of Schistosoma mansoni cercarial excretory/secretory products, prevents macrophage classical activation and delays antigen processing.
Q46107681Sorafenib perpetuates cellular anticancer effector functions by modulating the crosstalk between macrophages and natural killer cells.
Q37219806TEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma
Q42321642Tumor-mediated inhibition of human dendritic cell differentiation and function is consistently counteracted by combined p38 MAPK and STAT3 inhibition
Q37635491Tumour immunogenicity, antigen presentation and immunological barriers in cancer immunotherapy
Q30422500p38 MAPK-inhibited dendritic cells induce superior antitumour immune responses and overcome regulatory T-cell-mediated immunosuppression
Q36586138p38α senses environmental stress to control innate immune responses via mechanistic target of rapamycin
Q42932270β(2) integrins inhibit TLR responses by regulating NF-κB pathway and p38 MAPK activation

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