Remote ischemic preconditioning of cardiomyocytes inhibits the mitochondrial permeability transition pore independently of reduced calcium-loading or sarcKATP channel activation

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Remote ischemic preconditioning of cardiomyocytes inhibits the mitochondrial permeability transition pore independently of reduced calcium-loading or sarcKATP channel activation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.14814/PHY2.12231
P932PMC publication ID4255825
P698PubMed publication ID25428953
P5875ResearchGate publication ID268877964

P2093author name stringHelen E Turrell
Glenn Rodrigo
Chokanan Thaitirarot
Hayley Crumbie
P2860cites workKnockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energeticsQ44323106
Interaction of δ and κ opioid receptors with adenosine A1 receptors mediates cardioprotection by remote ischemic preconditioningQ44339072
Ischaemic preconditioning inhibits opening of mitochondrial permeability transition pores in the reperfused rat heartQ44401253
Stimulation of the plasma membrane Na+/H+ exchanger NHE1 by sustained intracellular acidosis. Evidence for a novel mechanism mediated by the ERK pathway.Q44468928
Resting membrane potential regulates Na(+)-Ca2+ exchange-mediated Ca2+ overload during hypoxia-reoxygenation in rat ventricular myocytes.Q44478881
Preconditioning delays Ca2+-induced mitochondrial permeability transitionQ44734187
Diazoxide causes early activation of cardiac sarcolemmal KATP channels during metabolic inhibition by an indirect mechanismQ44763887
Preconditioning with diazoxide prevents reoxygenation-induced rigor-type hypercontracture.Q46030331
Insulin inhibits Na+/H+ exchange in vascular smooth muscle and endothelial cells in situ: involvement of H2O2 and tyrosine phosphatase SHP-2.Q46226402
Role of mitochondrial re-energization and Ca2+ influx in reperfusion injury of metabolically inhibited cardiac myocytesQ46483566
Reduced effectiveness of HMR 1098 in blocking cardiac sarcolemmal K(ATP) channels during metabolic stress.Q46649600
Cardiac-specific ablation of the Na+-Ca2+ exchanger confers protection against ischemia/reperfusion injuryQ46716871
Hypoxia increases persistent sodium current in rat ventricular myocytes.Q51556510
Fluorescence measurements of cytoplasmic and mitochondrial sodium concentration in rat ventricular myocytesQ60182109
Endogenous cannabinoids contribute to remote ischemic preconditioning via cannabinoid CB2 receptors in the rat heartQ61453621
Ischaemic preconditioning reduces myocardial calcium overload in coronary-occluded pig hearts shown by continuous in vivo assessment using microdialysisQ62881648
Contraction band necrosis and irreversible myocardial injury.Q64913283
Role of intracellular Na+ in Ca2+ overload and depressed recovery of ventricular function of reperfused ischemic rat hearts. Possible involvement of H+-Na+ and Na+-Ca2+ exchangeQ69356843
Plasma membrane Na+/H+ exchanger isoforms (NHE-1, -2, and -3) are differentially responsive to second messenger agonists of the protein kinase A and C pathwaysQ71573471
Role of Na(+)/H(+) exchanger during ischemia and preconditioning in the isolated rat heartQ73082829
Rabbit heart can be "preconditioned" via transfer of coronary effluentQ73278993
Inhibition of the Na(+)/H(+) exchanger confers greater cardioprotection against 90 minutes of myocardial ischemia than ischemic preconditioning in dogsQ73289281
Intracellular free calcium and mitochondrial membrane potential in ischemia/reperfusion and preconditioningQ73910285
Na+/H+ exchanger activity does not contribute to protection by ischemic preconditioning in the isolated rat heartQ73936974
Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytesQ74771773
Remote ischemic preconditioning elaborates a transferable blood-borne effector that protects mitochondrial structure and function and preserves myocardial performance after neonatal cardioplegic arrestQ81765029
Remote cardioprotection by direct peripheral nerve stimulation and topical capsaicin is mediated by circulating humoral factorsQ83200594
The neural and humoral pathways in remote limb ischemic preconditioningQ84179559
Phenylephrine preconditioning involves modulation of cardiac sarcolemmal K(ATP) current by PKC delta, AMPK and p38 MAPKQ84527251
Transcutaneous electrical nerve stimulation as a novel method of remote preconditioning: in vitro validation in an animal model and first human observationsQ87412431
Calcium-mediated cell death during myocardial reperfusionQ26824881
Ischemic preconditioning of the whole heart confers protection on subsequently isolated ventricular myocytesQ28255150
ATP-regulated K+ channels in cardiac muscleQ28265565
Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardiumQ28304462
The KATP channel opener diazoxide protects cardiac myocytes during metabolic inhibition without causing mitochondrial depolarization or flavoprotein oxidationQ28361047
Creatine kinase is physically associated with the cardiac ATP-sensitive K+ channel in vivoQ28365561
Preconditioning protects by inhibiting the mitochondrial permeability transitionQ33201290
The role of the myocardial sodium-hydrogen exchanger in mediating ischemic and reperfusion injury. From amiloride to cariporideQ33692467
Preconditioning the Myocardium: From Cellular Physiology to Clinical CardiologyQ33972677
Remote preconditioning protects the heart by activating myocardial PKCepsilon-isoformQ34142598
Regional ischemic 'preconditioning' protects remote virgin myocardium from subsequent sustained coronary occlusionQ34305822
Do NHE inhibition and ischemic preconditioning convey cardioprotection through a common mechanism?Q34343962
The Driving Force of the Na/Ca-Exchanger during Metabolic Inhibition.Q34760285
Transient limb ischaemia remotely preconditions through a humoral mechanism acting directly on the myocardium: evidence suggesting cross-species protectionQ34931517
Role of the cardiac Na+/H+ exchanger during ischemia and reperfusionQ35090058
KATP channels and myocardial preconditioning: an updateQ35198367
Mitochondrial potassium transport: the role of the mitochondrial ATP-sensitive K(+) channel in cardiac function and cardioprotection.Q35542465
The first minutes of reperfusion: a window of opportunity for cardioprotectionQ35666872
ATP-sensitive potassium channelsQ36172853
Mitochondria and ischemia/reperfusion injuryQ36225172
Studying ischemic preconditioning in isolated cardiomyocyte modelsQ36368600
Calcium, mitochondria and reperfusion injury: a pore way to die.Q36424289
Epsilon protein kinase C as a potential therapeutic target for the ischemic heartQ36458796
The end-effectors of preconditioning protection against myocardial cell death secondary to ischemia-reperfusion.Q36458799
Remote ischaemic preconditioning: underlying mechanisms and clinical application.Q37154560
Healing the diabetic heart: does myocardial preconditioning work?Q37938329
The mechanism of early contractile failure of isolated rat ventricular myocytes subjected to complete metabolic inhibitionQ41284103
Characterization of the steady-state and dynamic fluorescence properties of the potential-sensitive dye bis-(1,3-dibutylbarbituric acid)trimethine oxonol (Dibac4(3)) in model systems and cellsQ41490432
Cardioprotection evoked by remote ischaemic preconditioning is critically dependent on the activity of vagal pre-ganglionic neuronesQ41780101
Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusionQ41977320
The rise of [Na(+)] (i) during ischemia and reperfusion in the rat heart-underlying mechanismsQ42172121
Pretreatment with the nitric oxide donor SNAP or nerve transection blocks humoral preconditioning by remote limb ischemia or intra-arterial adenosineQ42923089
Pharmacological activation of plasma-membrane KATP channels reduces reoxygenation-induced Ca(2+) overload in cardiac myocytes via modulation of the diastolic membrane potentialQ43263045
Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?Q44088292
Effect of inhibition of Na(+)/Ca(2+) exchanger at the time of myocardial reperfusion on hypercontracture and cell deathQ44100828
Ischemic preconditioning alters real-time measure of O2 radicals in intact hearts with ischemia and reperfusionQ44203658
P433issue11
P577publication date2014-11-26
P1433published inPhysiological ReportsQ15716763
P1476titleRemote ischemic preconditioning of cardiomyocytes inhibits the mitochondrial permeability transition pore independently of reduced calcium-loading or sarcKATP channel activation
P478volume2

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cites work (P2860)
Q41859105Involvement of neuronal pathways in the protective effects of hindlimb perconditioning during renal ischemia.
Q28072918Ischaemic conditioning and targeting reperfusion injury: a 30 year voyage of discovery
Q59514129Kardioprotektion über den Arm?
Q48012446No influence of ischemic preconditioning on running economy
Q38833919Remote ischaemic conditioning and remodelling following myocardial infarction: current evidence and future perspectives
Q52680476Remote ischemic conditioning improves myocardial parameters and clinical outcomes during primary percutaneous coronary intervention: a meta-analysis of randomized controlled trials.
Q38660549The application of remote ischemic conditioning in cardiac surgery

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