Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain

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Werner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M701042200
P698PubMed publication ID17550899

P2093author name stringMichael P Myers
Rebecca A Bish
P2860cites workNoncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repairQ22009084
Dysfunction of human Rad18 results in defective postreplication repair and hypersensitivity to multiple mutagensQ22254567
Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase deltaQ24292690
Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitinQ24293055
Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stressQ24300945
BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repairQ24310221
Yeast cycloheximide-resistant crl mutants are proteasome mutants defective in protein degradationQ38615074
Saccharomyces cerevisiae MGS1 is essential in strains deficient in the RAD6-dependent DNA damage tolerance pathwayQ39647056
A ubiquitin mutant with specific defects in DNA repair and multiubiquitinationQ40015739
Localisation of human Y-family DNA polymerase kappa: relationship to PCNA foci.Q40480425
The Saccharomyces cerevisiae RAD18 gene encodes a protein that contains potential zinc finger domains for nucleic acid binding and a putative nucleotide binding sequenceQ40554098
Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virusQ41079949
Recognition of specific ubiquitin conjugates is important for the proteolytic functions of the ubiquitin-associated domain proteins Dsk2 and Rad23.Q43862937
The CCT chaperonin promotes activation of the anaphase-promoting complex through the generation of functional Cdc20.Q44530413
Postreplication repair of DNA in ultraviolet-irradiated mammalian cellsQ44587841
RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysisQ44681202
Molecular mechanisms of coupled monoubiquitinationQ57964128
The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitinQ24312959
Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseasesQ24317166
Stimulation of DNA synthesis activity of human DNA polymerase kappa by PCNA.Q24537135
Physical and functional interactions of human DNA polymerase eta with PCNAQ24548300
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysisQ27860815
A yeast gene, MGS1, encoding a DNA-dependent AAA(+) ATPase is required to maintain genome stability.Q27931070
Functions of the DNA damage response pathway target Ho endonuclease of yeast for degradation via the ubiquitin-26S proteasome systemQ27934435
Cluster analysis of mass spectrometry data reveals a novel component of SAGAQ27937089
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.Q27937465
Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activitiesQ27938794
Functional and physical interaction of yeast Mgs1 with PCNA: impact on RAD6-dependent DNA damage toleranceQ27938957
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chainQ28142613
Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligaseQ28187365
A novel protein interacts with the Werner's syndrome gene product physically and functionallyQ28212274
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutationQ28246858
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2Q28277364
Differential regulation of Rad18 through Rad6-dependent mono- and polyubiquitinationQ28290146
A multiubiquitin chain is confined to specific lysine in a targeted short-lived proteinQ29547884
TANDEM: matching proteins with tandem mass spectraQ29615238
Ubiquitin signalling in the NF-kappaB pathwayQ29616322
Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosisQ29617390
Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expressionQ29619380
Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesisQ29619757
Replication-dependent and -independent responses of RAD18 to DNA damage in human cellsQ33257837
The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactionsQ33693921
Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC.Q33886538
The xeroderma pigmentosum group E gene product DDB2 is a specific target of cullin 4A in mammalian cellsQ34012408
Direct identification of a G protein ubiquitination site by mass spectrometryQ34123833
PDSM, a motif for phosphorylation-dependent SUMO modificationQ34248164
UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex.Q34417183
Ubiquitin depletion as a key mediator of toxicity by translational inhibitorsQ34986792
Large-scale phosphorylation analysis of mouse liverQ35616333
Human RAD18 is involved in S phase-specific single-strand break repair without PCNA monoubiquitinationQ35646843
Regulation of DNA repair by ubiquitylationQ36457732
The t-complex polypeptide 1 complex is a chaperonin for tubulin and actin in vivo.Q36591894
P433issue32
P407language of work or nameEnglishQ1860
P304page(s)23184-23193
P577publication date2007-06-05
P1433published inJournal of Biological ChemistryQ867727
P1476titleWerner helicase-interacting protein 1 binds polyubiquitin via its zinc finger domain
P478volume282

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cites work (P2860)
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Q97518575WRNIP1 Is Recruited to DNA Interstrand Crosslinks and Promotes Repair
Q24293429ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase