BRG1 is a prognostic marker and potential therapeutic target in human breast cancer

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BRG1 is a prognostic marker and potential therapeutic target in human breast cancer is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...859772B
P356DOI10.1371/JOURNAL.PONE.0059772
P932PMC publication ID3606107
P698PubMed publication ID23533649
P5875ResearchGate publication ID236085182

P2093author name stringHui Liu
Feifei Chen
Chen Li
Cuipeng Zhang
Jin Bai
Junnian Zheng
Pengjin Mei
Zhenqiang Pan
P2860cites workCyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrestQ22008677
BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancerQ24273430
Diversity and specialization of mammalian SWI/SNF complexesQ24322918
BRG1, a component of the SWI-SNF complex, is mutated in multiple human tumor cell linesQ28138156
Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-upQ28306437
A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexesQ28589309
Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanomaQ33578231
The BRG1 chromatin remodeler protects against ovarian cysts, uterine tumors, and mammary tumors in a lineage-specific mannerQ34170839
When the SWI/SNF complex remodels...the cell cycleQ34290272
Chromatin remodelling during developmentQ34698385
[Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue]Q68175965
Increased expression but not genetic alteration of BRG1, a component of the SWI/SNF complex, is associated with the advanced stage of human gastric carcinomasQ77222548
Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genesQ79266982
Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness.Q34992490
Identification of a core member of the SWI/SNF complex, BAF155/SMARCC1, as a human tumor suppressor geneQ35667390
Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expressionQ36354441
Matrix metalloproteinases and tumor metastasisQ36471104
Requirement for chromatin-remodeling complex in novel tumor suppressor HIC1-mediated transcriptional repression and growth controlQ37085986
BRG1 and LKB1: tales of two tumor suppressor genes on chromosome 19p and lung cancer.Q37379574
The SWI/SNF complex and cancerQ37398568
Breast cancer statistics, 2011Q37942073
Diverse functions of ATP-dependent chromatin remodeling complexes in development and cancerQ37970954
MLK3 Regulates Paxillin Phosphorylation in Chemokine-Mediated Breast Cancer Cell Migration and Invasion to Drive MetastasisQ39330842
BRG1 expression is increased in human glioma and controls glioma cell proliferation, migration and invasion in vitroQ39391018
Loss of expression of the SWI/SNF chromatin remodeling subunit BRG1/SMARCA4 is frequently observed in intraductal papillary mucinous neoplasms of the pancreasQ39469747
RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migrationQ39472960
BRG1 expression is increased in human cutaneous melanomaQ39701593
The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.Q39850197
Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancersQ40213912
Role for BRG1 in cell cycle control and tumor suppressionQ40376914
Chromatin structure and DNA damage repairQ41189289
Regulation of PTEN expression by the SWI/SNF chromatin-remodelling protein BRG1 in human colorectal carcinoma cells.Q42276895
BRM and BRG1 subunits of the SWI/SNF chromatin remodelling complex are downregulated upon progression of benign skin lesions into invasive tumours.Q42488147
Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.Q47233081
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectbreast cancerQ128581
P304page(s)e59772
P577publication date2013-03-22
P1433published inPLOS OneQ564954
P1476titleBRG1 is a prognostic marker and potential therapeutic target in human breast cancer
P478volume8

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cites work (P2860)
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