| scholarly article | Q13442814 |
| P2093 | author name string | Jian Chen | |
| Kathleen A. Gallo | |||
| P2860 | cites work | Involvement of chemokine receptors in breast cancer metastasis | Q24290909 |
| MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation | Q24299564 | ||
| Regulation of mixed lineage kinase 3 is required for Neurofibromatosis-2-mediated growth suppression in human cancer | Q24301750 | ||
| EphB1-mediated cell migration requires the phosphorylation of paxillin at Tyr-31/Tyr-118. | Q40563260 | ||
| An apoptotic signaling pathway in the interferon antiviral response mediated by RNase L and c-Jun NH2-terminal kinase | Q40624332 | ||
| Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis. | Q42823593 | ||
| MLK3 is critical for breast cancer cell migration and promotes a malignant phenotype in mammary epithelial cells | Q43049711 | ||
| Tissue microarray analysis of hepatocyte growth factor/Met pathway components reveals a role for Met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer | Q44342338 | ||
| C-Met overexpression in node-positive breast cancer identifies patients with poor clinical outcome independent of Her2/neu | Q45083973 | ||
| A paxillin tyrosine phosphorylation switch regulates the assembly and form of cell-matrix adhesions | Q51926838 | ||
| A gene expression signature associated with metastatic cells in effusions of breast carcinoma patients | Q53558013 | ||
| Decreased expression of phosphorylated JNK in breast infiltrating ductal carcinoma is associated with a better overall survival | Q82100297 | ||
| A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis | Q24649156 | ||
| Expression pattern of CXC chemokine receptor-4 is correlated with lymph node metastasis in human invasive ductal carcinoma | Q24803472 | ||
| An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation | Q27325523 | ||
| Nudel and FAK as antagonizing strength modulators of nascent adhesions through paxillin | Q27330292 | ||
| Rho GTPases and the Actin Cytoskeleton | Q27860579 | ||
| Cell migration: integrating signals from front to back | Q27860670 | ||
| Met, metastasis, motility and more | Q28235183 | ||
| Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase | Q28293659 | ||
| JNK phosphorylates paxillin and regulates cell migration | Q28575982 | ||
| Rho GTPases control polarity, protrusion, and adhesion during cell movement | Q29614244 | ||
| FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly | Q29616029 | ||
| Cdc42 induces activation loop phosphorylation and membrane targeting of mixed lineage kinase 3. | Q30160092 | ||
| Autoinhibition of mixed lineage kinase 3 through its Src homology 3 domain | Q30167889 | ||
| Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells | Q30175229 | ||
| Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration | Q30441909 | ||
| Focal adhesion kinase: targeting adhesion signaling pathways for therapeutic intervention | Q30445536 | ||
| pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk | Q30452729 | ||
| Mixed lineage kinase-3/JNK1 axis promotes migration of human gastric cancer cells following gastrin stimulation | Q33641941 | ||
| The Met oncogene and basal-like breast cancer: another culprit to watch out for? | Q34173500 | ||
| Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion | Q34243424 | ||
| Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase | Q34419052 | ||
| Mixed-lineage kinase control of JNK and p38 MAPK pathways | Q34810173 | ||
| Paxillin: adapting to change | Q35895201 | ||
| Metabolic stress signaling mediated by mixed-lineage kinases | Q36002831 | ||
| Functions of CXCL12 and CXCR4 in breast cancer | Q36208303 | ||
| The role of focal-adhesion kinase in cancer - a new therapeutic opportunity | Q36216076 | ||
| MLK3 limits activated Galphaq signaling to Rho by binding to p63RhoGEF. | Q37016882 | ||
| Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration | Q37323621 | ||
| Breast cancer statistics, 2011 | Q37942073 | ||
| Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis | Q39433444 | ||
| Identification of genes that regulate epithelial cell migration using an siRNA screening approach | Q39892281 | ||
| JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin | Q39949189 | ||
| Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines | Q40168416 | ||
| Epidermal growth factor induces insulin receptor substrate-2 in breast cancer cells via c-Jun NH(2)-terminal kinase/activator protein-1 signaling to regulate cell migration | Q40278687 | ||
| Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells. | Q40291702 | ||
| Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcoma | Q40426949 | ||
| Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells | Q40525953 | ||
| P433 | issue | 16 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | breast cancer | Q128581 |
| cell migration | Q189092 | ||
| phosphorylation | Q242736 | ||
| P304 | page(s) | 4130-4140 | |
| P577 | publication date | 2012-06-13 | |
| P1433 | published in | Cancer Research | Q326097 |
| P1476 | title | MLK3 regulates paxillin phosphorylation in chemokine-mediated breast cancer cell migration and invasion to drive metastasis | |
| MLK3 Regulates Paxillin Phosphorylation in Chemokine-Mediated Breast Cancer Cell Migration and Invasion to Drive Metastasis | |||
| P478 | volume | 72 |
| Q35357838 | A novel aminothiazole KY-05009 with potential to inhibit Traf2- and Nck-interacting kinase (TNIK) attenuates TGF-β1-mediated epithelial-to-mesenchymal transition in human lung adenocarcinoma A549 cells |
| Q34528291 | Antitumor action of a novel histone deacetylase inhibitor, YF479, in breast cancer |
| Q34637961 | BRG1 is a prognostic marker and potential therapeutic target in human breast cancer |
| Q34984681 | CK2 inhibitor CX-4945 blocks TGF-β1-induced epithelial-to-mesenchymal transition in A549 human lung adenocarcinoma cells |
| Q35993392 | Computational Identification of Key Regulators in Two Different Colorectal Cancer Cell Lines. |
| Q36918767 | Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin |
| Q36516725 | Decrement of miR-199a-5p contributes to the tumorigenesis of bladder urothelial carcinoma by regulating MLK3/NF-κB pathway |
| Q35120706 | Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation |
| Q39227726 | Functional effects of SDF-1α on a CD44+ CXCR4+ squamous cell carcinoma cell line as a model for interactions in the cancer stem cell niche |
| Q37607600 | IL-1β-induced activation of p38 promotes metastasis in gastric adenocarcinoma via upregulation of AP-1/c-fos, MMP2 and MMP9 |
| Q38102775 | Involvement of mixed lineage kinase 3 in cancer |
| Q35934889 | KSHV gB associated RGD interactions promote attachment of cells by inhibiting the potential migratory signals induced by the disintegrin-like domain |
| Q39134034 | Knockdown of FAK inhibits the invasion and metastasis of Tca-8113 cells in vitro |
| Q38794213 | Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling |
| Q36561985 | Lysine 63-linked Ubiquitination Modulates Mixed Lineage Kinase-3 Interaction with JIP1 Scaffold Protein in Cytokine-induced Pancreatic β Cell Death |
| Q30366227 | MEKK2 regulates paxillin ubiquitylation and localization in MDA-MB 231 breast cancer cells. |
| Q26746892 | MLK3 Signaling in Cancer Invasion |
| Q90666238 | MLK3 is a newly identified microRNA-520b target that regulates liver cancer cell migration |
| Q46272315 | MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells |
| Q39014798 | MLK3 promotes melanoma proliferation and invasion and is a target of microRNA-125b |
| Q41072269 | MLK3 regulates FRA-1 and MMPs to drive invasion and transendothelial migration in triple-negative breast cancer cells |
| Q30009504 | MLK3 regulates fMLP-stimulated neutrophil motility |
| Q38699266 | Metastasis of breast cancer cells to the bone, lung, and lymph nodes promotes resistance to ionizing radiation. |
| Q38952716 | MiR-137: an important player in neural development and neoplastic transformation. |
| Q36632432 | Minireview: Mouse Models of Rho GTPase Function in Mammary Gland Development, Tumorigenesis, and Metastasis |
| Q37392541 | Mixed Lineage Kinase-c-Jun N-Terminal Kinase Axis: A Potential Therapeutic Target in Cancer |
| Q33855025 | Mixed-lineage kinase 3 deficiency promotes neointima formation through increased activation of the RhoA pathway in vascular smooth muscle cells |
| Q52362244 | Molecular Mechanisms and Emerging Therapeutic Targets of Triple-Negative Breast Cancer Metastasis. |
| Q42099107 | Molecular pathways: targeting the kinase effectors of RHO-family GTPases |
| Q97568292 | Nicotine inhibits MAPK signaling and spheroid invasion in ovarian cancer cells |
| Q48011345 | Osmotic and heat stress-dependent regulation of MLK4β and MLK3 by the CHIP E3 ligase in ovarian cancer cells |
| Q35047000 | Overexpression of C-terminal fragment of glutamate receptor 6 prevents neuronal injury in kainate-induced seizure via disassembly of GluR6-PSD-95-MLK3 signaling module |
| Q36962403 | Overexpression of miR-199a-5p decreases esophageal cancer cell proliferation through repression of mitogen-activated protein kinase kinase kinase-11 (MAP3K11). |
| Q37413818 | Paxillin and steroid signaling: from frog to human. |
| Q42095789 | Paxillin expression is closely linked to the pathogenesis, progression and prognosis of gastric carcinomas |
| Q37650990 | Paxillin: a crossroad in pathological cell migration |
| Q34268838 | Pharmacologic inhibition of MLK3 kinase activity blocks the in vitro migratory capacity of breast cancer cells but has no effect on breast cancer brain metastasis in a mouse xenograft model |
| Q35497283 | PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway. |
| Q58549630 | Regulation of RhoA activation and cell motility by c-Jun N-terminal kinases and Net1 |
| Q37289439 | SREBP-1 is an independent prognostic marker and promotes invasion and migration in breast cancer |
| Q37207651 | Targeting mixed lineage kinases in ER-positive breast cancer cells leads to G2/M cell cycle arrest and apoptosis |
| Q36852491 | Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling. |
| Q44283570 | Tenascin-C induces migration and invasion through JNK/c-Jun signalling in pancreatic cancer |
| Q34056529 | The E3 ligase CHIP mediates ubiquitination and degradation of mixed-lineage kinase 3 |
| Q90132454 | miR-125a-5p inhibits tumorigenesis in hepatocellular carcinoma |
| Q39062167 | miR-137 impairs the proliferative and migratory capacity of human non-small cell lung cancer cells by targeting paxillin |
Search more.