Surfactant protein-A modulates LPS-induced TLR4 localization and signaling via β-arrestin 2

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Surfactant protein-A modulates LPS-induced TLR4 localization and signaling via β-arrestin 2 is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...859896S
P356DOI10.1371/JOURNAL.PONE.0059896
P8608Fatcat IDrelease_oa435a46nvg27dhyn3xdi5mlmm
P932PMC publication ID3607558
P698PubMed publication ID23536892
P5875ResearchGate publication ID236088352

P2093author name stringCordula Stamme
Vicky Sender
Linda Lang
P2860cites workAssociation of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signalingQ24299892
Rab7b controls trafficking from endosomes to the TGNQ24306089
Functional specialization of beta-arrestin interactions revealed by proteomic analysisQ24318455
Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathwaysQ24338654
Role of clathrin-mediated endocytosis of surfactant protein A by alveolar macrophages in intracellular signaling.Q53424800
Surfactant protein A activation of atypical protein kinase C zeta in IkappaB-alpha-dependent anti-inflammatory immune regulation.Q53526894
Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivoQ56655892
Surfactant apoprotein Mr = 26,000-36,000 enhances uptake of liposomes by type II cellsQ69752908
Distinct effects of surfactant protein A or D deficiency during bacterial infection on the lungQ73084779
Surfactant protein A differentially regulates IFN-gamma- and LPS-induced nitrite production by rat alveolar macrophagesQ73265425
Surfactant protein a inhibits lipopolysaccharide-induced immune cell activation by preventing the interaction of lipopolysaccharide with lipopolysaccharide-binding proteinQ74694427
Recycling endosomes and TLR signaling--the Rab11 GTPase leads the wayQ82208752
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptorsQ27860900
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transductionQ28203920
Enhanced morphine analgesia in mice lacking beta-arrestin 2Q28504554
Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4Q28589222
By Binding SIRPα or Calreticulin/CD91, Lung Collectins Act as Dual Function Surveillance Molecules to Suppress or Enhance InflammationQ28609700
Innate immune responses to bacterial ligands in the peripheral human lung--role of alveolar epithelial TLR expression and signallingQ28742573
Surfactant Proteins A and D Bind CD14 by Different MechanismsQ29392656
Rab7: a key to lysosome biogenesisQ29620369
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunityQ30476891
Differential expression of Toll-like receptors on human alveolar macrophages and autologous peripheral monocytes.Q33634527
Teaching old receptors new tricks: biasing seven-transmembrane receptorsQ33985759
Regulation of lipopolysaccharide-induced inflammatory response and endotoxemia by beta-arrestinsQ34091848
Pulmonary collectins and innate host defense of the lungQ34184446
Endocytic pathway for surfactant protein A in human macrophages: binding, clathrin-mediated uptake, and trafficking through the endolysosomal pathwayQ34451893
beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha.Q34513767
Beta-arrestin-2 regulates the development of allergic asthmaQ35242857
Immunoregulatory functions of surfactant proteinsQ35998804
Toll-like receptor 4 resides in the Golgi apparatus and colocalizes with internalized lipopolysaccharide in intestinal epithelial cellsQ36370326
Transport of bacterial lipopolysaccharide to the golgi apparatusQ36375236
Surfactant-associated protein A provides critical immunoprotection in neonatal mice.Q36422110
A cell biological view of Toll-like receptor function: regulation through compartmentalization.Q37531879
Pulmonary surfactant: an immunological perspectiveQ37669627
Localisation and trafficking of Toll-like receptors: an important mode of regulation.Q37671100
Beta-arrestins as regulators of signal termination and transduction: How do they determine what to scaffold?Q37800215
Pulmonary surfactant protein A enhances endolysosomal trafficking in alveolar macrophages through regulation of Rab7.Q39605567
Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survivalQ39794781
Surfactant protein A enhances production of secretory leukoprotease inhibitor and protects it from cleavage by matrix metalloproteinasesQ39893097
Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4.Q40065770
Surfactant protein A directly interacts with TLR4 and MD-2 and regulates inflammatory cellular response. Importance of supratrimeric oligomerizationQ40271321
Pulmonary surfactant protein A modulates the cellular response to smooth and rough lipopolysaccharides by interaction with CD14.Q40945519
Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression.Q42420177
Pulmonary surfactant protein A regulates TLR expression and activity in human macrophagesQ42436985
Surfactant protein-A--deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virusQ43627168
Beta-arrestin 2 negatively regulates sepsis-induced inflammationQ43861679
Loss of betaarrestin1 and betaarrestin2 contributes to pulmonary hypoplasia and neonatal lethality in mice.Q43994613
Electrodialysis of Lipopolysaccharides and Their Conversion to Uniform Salt FormsQ44118828
Surfactant protein A inhibits alveolar macrophage cytokine production by CD14-independent pathwayQ44575970
Accumulation of inhibitory kappaB-alpha as a mechanism contributing to the anti-inflammatory effects of surfactant protein-A.Q45016505
Essential role of MD-2 in LPS responsiveness and TLR4 distributionQ50109313
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
P304page(s)e59896
P577publication date2013-03-25
P1433published inPLOS OneQ564954
P1476titleSurfactant protein-A modulates LPS-induced TLR4 localization and signaling via β-arrestin 2
P478volume8

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cites work (P2860)
Q34471243Eosinophil-associated lung diseases. A cry for surfactant proteins A and D help?
Q61796045Indispensable role of β-arrestin2 in the protection of remifentanil preconditioning against hepatic ischemic reperfusion injury
Q46699315Inhibition of TLR4 attenuates vascular dysfunction and oxidative stress in diabetic rats.
Q38241199Lung cell-specific modulation of LPS-induced TLR4 receptor and adaptor localization
Q37565264MicroRNA-27a promotes renal tubulointerstitial fibrosis via suppressing PPARγ pathway in diabetic nephropathy
Q37265312Oral administration of surfactant protein-a reduces pathology in an experimental model of necrotizing enterocolitis.
Q28116165SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation
Q40103487Surfactant Protein A Enhances Constitutive Immune Functions of Clathrin Heavy Chain and Clathrin Adaptor Protein 2.
Q48210833Surfactant Protein A Prevents IFN-γ/IFN-γ Receptor Interaction and Attenuates Classical Activation of Human Alveolar Macrophages.
Q58036012The Role of Collectins and Galectins in Lung Innate Immune Defense
Q38136811β-Arrestins 1 and 2 are critical regulators of inflammation.

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