Adipose inflammation: cause or consequence of obesity-related insulin resistance

scientific article

Adipose inflammation: cause or consequence of obesity-related insulin resistance is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P932PMC publication ID3052712
P698PubMed publication ID21437153

P2093author name stringHaiyan Xu
Ping Jiao
P2860cites workDefective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 GeneQ22299417
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistanceQ24617743
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CCR2 modulates inflammatory and metabolic effects of high-fat feedingQ29622869
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humansQ29622900
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Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feedingQ33337750
Visceral adipose tissue inflammation accelerates atherosclerosis in apolipoprotein E-deficient mice.Q33554780
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistanceQ33997240
Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intoleranceQ34137882
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alphaQ34190131
Evidence for a potent antiinflammatory effect of rosiglitazoneQ34325011
Monocyte chemoattractant protein 1 in obesity and insulin resistanceQ35163496
Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinedionesQ35794061
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Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient miceQ37242527
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Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight lossQ38323163
Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesityQ38330921
Low-dose rosiglitazone exerts an antiinflammatory effect with an increase in adiponectin independently of free fatty acid fall and insulin sensitization in obese type 2 diabeticsQ40312091
High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetesQ40663999
Preadipocyte conversion to macrophage. Evidence of plasticity.Q40678700
Signaling pathways utilized by tumor necrosis factor receptor 1 in adipocytes to suppress differentiationQ40776227
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.Q40816506
A role for preadipocytes as macrophage-like cellsQ40974181
Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipaseQ41462901
Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjectsQ42797512
Altered tumor necrosis factor-alpha (TNF-alpha) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesityQ42814772
Exclusive action of transmembrane TNF alpha in adipose tissue leads to reduced adipose mass and local but not systemic insulin resistanceQ43920014
Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis studyQ43935468
Serum concentration of alpha-2-macroglobulin, haptoglobin and alpha-1-antitrypsin in diabetes mellitusQ44224801
Circulating mononuclear cells in the obese are in a proinflammatory stateQ45057039
Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazoneQ46620643
Weight loss regulates inflammation-related genes in white adipose tissue of obese subjectsQ47402001
Targeted disruption of the tumor necrosis factor-alpha gene: metabolic consequences in obese and nonobese miceQ48630964
NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X.Q50920620
Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity.Q51497448
Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.Q53556065
Reduction of blood fibrinolytic activity in diabetes mellitus by insulin.Q53926197
FIBRINOLYSIS IN OBESITYQ53973972
Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates.Q54223604
Aspirin and diabetes mellitus.Q55420667
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistanceQ56742768
Chemokines control fat accumulation and leptin secretion by cultured human adipocytesQ57076426
PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory PropertiesQ57244208
Reappraisal of the hypoglycemic action of acetylsalicylate.Q64982618
Serum sialic acid and acute phase proteins in type 1 and type 2 diabetes mellitusQ71609492
KB-R7785, a novel matrix metalloproteinase inhibitor, exerts its antidiabetic effect by inhibiting tumor necrosis factor-alpha productionQ73635302
Transmembrane tumor necrosis factor (TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor 1Q78208083
Obesity and the environment: where do we go from here?Q78947050
Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesityQ79996607
Adipocyte death, adipose tissue remodeling, and obesity complicationsQ81234708
On the Treatment of Glycosuria and Diabetes Mellitus with Sodium SalicylateQ84870452
P921main subjectobesityQ12174
inflammationQ101991
insulin resistanceQ1053470
preproinsulinQ7240673
P304page(s)25-31
P577publication date2008-10-23
P1433published inDiabetes, Metabolic Syndrome and Obesity: Targets and TherapyQ5270108
P1476titleAdipose inflammation: cause or consequence of obesity-related insulin resistance
P478volume1

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cites work (P2860)
Q49400243Adipocytokines in obese Ghanaian subjects with or without type 2 diabetes
Q35810634Deficiency of ACE2 in Bone-Marrow-Derived Cells Increases Expression of TNF-α in Adipose Stromal Cells and Augments Glucose Intolerance in Obese C57BL/6 Mice
Q86309075Inflammatory Signaling Involved in High-Fat Diet Induced Prostate Diseases
Q41101306Overfat Adults and Children in Developed Countries: The Public Health Importance of Identifying Excess Body Fat.
Q33972551Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey
Q37704979microRNAs as a new mechanism regulating adipose tissue inflammation in obesity and as a novel therapeutic strategy in the metabolic syndrome

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