Chemokines control fat accumulation and leptin secretion by cultured human adipocytes

scientific article published on 01 April 2001

Chemokines control fat accumulation and leptin secretion by cultured human adipocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0303-7207(01)00394-X
P698PubMed publication ID11325518

P50authorIgnacio A. RomeroQ37605522
Luc CamoinQ55644814
P2093author name stringA D Strosberg
R Cancello
C C Gerhardt
P2860cites workImpaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient miceQ24681021
Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) proceduresQ26778382
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin ResistanceQ28131660
Intracellular signalling pathways induced by chemokines in natural killer cellsQ28139266
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tractQ28504884
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar developmentQ28512895
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppressionQ28594263
Leptin and the regulation of body weight in mammalsQ29615976
Chemokines and leukocyte trafficQ29618886
Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B geneQ29618933
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activationQ29620219
Tumour necrosis factor, a key role in obesity?Q33661065
Tumor necrosis factor alpha inhibits signaling from the insulin receptorQ35304189
Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell lineQ36356054
Multiple cytokines and acute inflammation raise mouse leptin levels: potential role in inflammatory anorexiaQ36376685
Cloning and characterization of a cDNA for murine macrophage inflammatory protein (MIP), a novel monokine with inflammatory and chemokinetic propertiesQ36445746
A new class of obesity genes encodes leukocyte adhesion receptorsQ36659846
Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.Q36837473
Reversing adipocyte differentiation: implications for treatment of obesityQ37185181
Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamstersQ37354703
Tumor necrosis factor-alpha contributes to obesity-related hyperleptinemia by regulating leptin release from adipocytesQ37375694
Human leptin stimulates proliferation and activation of human circulating monocytesQ38324048
The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathwaysQ41012131
The role of chemokines in inflammationQ41328542
Modulation of adipocyte differentiation by tumor necrosis factor and transforming growth factor betaQ41568089
Cytokines and cachexiaQ41588874
Chemokine receptor CCR2 and CCR5 polymorphisms in children with insulin-dependent diabetes mellitusQ42474483
Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alphaQ42807467
Quantitation of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O.Q42818414
RANTES induces tyrosine kinase activity of stably complexed p125FAK and ZAP-70 in human T cellsQ42943759
Chemokines: understanding their role in T-lymphocyte biology.Q42991198
Interleukin-8 as a macrophage-derived mediator of angiogenesisQ44053300
Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein SlimbQ47070747
Growth factor activity of endothelin-1 in primary astrocytes mediated by adhesion-dependent and -independent pathwaysQ48637349
Chemokines: signal lamps for trafficking of T and B cells for development and effector function.Q52035782
Endothelial cell gene expression of a neutrophil chemotactic factor by TNF-alpha, LPS, and IL-1 betaQ69491342
Human vascular smooth muscle cells express receptors for CC chemokinesQ74351441
Transcriptional control of adipogenesisQ74485015
Leptin: fundamental aspectsQ77292322
Adipose tissue as an endocrine and paracrine organQ77758550
Down regulation of peroxisome proliferator-activated receptorgamma expression by inflammatory cytokines and its reversal by thiazolidinedionesQ77924509
P433issue1-2
P921main subjectadipocyteQ357519
P304page(s)81-92
P577publication date2001-04-01
P1433published inMolecular and Cellular EndocrinologyQ1573600
P1476titleChemokines control fat accumulation and leptin secretion by cultured human adipocytes
P478volume175

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cites work (P2860)
Q27026242A Potential Role for Pro-Inflammatory Cytokines in the Development of Insulin Resistance in Horses
Q83061993Acute and prolonged effects of TNF-alpha on the expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture
Q26830077Adipocytes: impact on tumor growth and potential sites for therapeutic intervention
Q34642513Adipose inflammation: cause or consequence of obesity-related insulin resistance
Q26995063Adipose tissue, diabetes and Chagas disease
Q34413809Alterations of leptin in the course of inflammation and severe sepsis
Q36226553Angiogenic, lymphangiogenic and adipogenic effects of HIV-1 matrix protein p17.
Q42495467Angiotensin II induces monocyte chemoattractant protein-1 expression via a nuclear factor-kappaB-dependent pathway in rat preadipocytes
Q45233127Anti-oxidant status in relation to lipoproteins, leptin and pro-inflammatory cytokines in children with steroid-sensitive nephrotic syndrome.
Q45045301Association between the A-2518G polymorphism in the monocyte chemoattractant protein-1 gene and insulin resistance and Type 2 diabetes mellitus
Q38034269At the crossroad of T cells, adipose tissue, and diabetes
Q51655301Bivariate whole-genome linkage scan for bone geometry and total body fat mass.
Q41649318CXCL3 positively regulates adipogenic differentiation
Q35739799Cardiovascular implications of HIV-associated dyslipidemic lipodystrophy
Q46623843Caucasian patients with type 2 diabetes mellitus have elevated levels of monocyte chemoattractant protein-1 that are not influenced by the -2518 A-->G promoter polymorphism
Q30498100Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue
Q89446797Cellular toxicity of silicon carbide nanomaterials as a function of morphology
Q35829203Central obesity, type 2 diabetes and insulin: exploring a pathway full of thorns
Q41422172Chagas disease, adipose tissue and the metabolic syndrome
Q35772686Characterization of In Vitro Engineered Human Adipose Tissues: Relevant Adipokine Secretion and Impact of TNF-α.
Q45382089Characterization of herpes virus entry mediator as a factor linked to obesity
Q37692555Chemokine network during adipogenesis in 3T3-L1 cells: Differential response between growth and proinflammatory factor in preadipocytes vs. adipocytes
Q36963161Chemokines and chemokine receptors in neurological disease: raise, retain, or reduce?
Q43489113Chemokines as risk factors for type 2 diabetes: results from the MONICA/KORA Augsburg study, 1984-2002.
Q37583987Chemotactic cytokines, obesity and type 2 diabetes: in vivo and in vitro evidence for a possible causal correlation?
Q46988914Circulating levels of MCP-1 and IL-8 are elevated in human obese subjects and associated with obesity-related parameters
Q34312856Conjugated linoleic acid induces human adipocyte delipidation: autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines
Q34147790Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production.
Q34345275Cord blood leptin levels of healthy neonates are associated with IFN-γ production by cord blood T-cells
Q37281338Cytokine-Rich Adipose Tissue Extract Production from Water-Assisted Lipoaspirate: Methodology for Clinical Use
Q37142048Dibutyryl-cAMP affecting fat deposition of finishing pigs by decreasing the inflammatory system related to insulin sensitive or lipolysis
Q52566078Diet induction of monocyte chemoattractant protein-1 and its impact on obesity.
Q36292566Differential adipogenic and inflammatory properties of small adipocytes in Zucker Obese and Lean rats
Q38981451Effect of Sipjeondaebo-tang on cancer-induced anorexia and cachexia in CT-26 tumor-bearing mice
Q46954618Effect of short-term folic acid supplementation on insulin sensitivity and inflammatory markers in overweight subjects.
Q35789994Effects of a healthy life exercise program on arteriosclerosis adhesion molecules in elderly obese women
Q39166897Effects of long-term exercise training on adipose tissue expression of fractalkine and MCP-1 in patients with type 2 diabetes and stable coronary artery disease: a substudy of a randomized controlled trial
Q48612749Effects of pro-inflammatory cytokines and chemokines on leptin production in human adipose tissue in vitro.
Q73031835Elevation of cytokine levels in cachectic patients with prostate carcinoma
Q28589295Fam57b (family with sequence similarity 57, member B), a novel peroxisome proliferator-activated receptor γ target gene that regulates adipogenesis through ceramide synthesis
Q38669187From neutrophils to macrophages: differences in regional adipose tissue depots
Q34950987Gene expression and protein secretion during human mesenchymal cell differentiation into adipogenic cells.
Q39362988Human adipose tissue macrophages display activation of cancer-related pathways
Q41878282Human monocytes accelerate proliferation and blunt differentiation of preadipocytes in association with suppression of C/EBPΑ mRNA.
Q37132401Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity?
Q34168259Impact of macrophage inflammatory protein-1α deficiency on atherosclerotic lesion formation, hepatic steatosis, and adipose tissue expansion
Q37255877Inflamed adipose tissue, insulin resistance and vascular injury
Q82953450Inflammatory markers in a randomised soya intervention among men
Q37156416Influence of elevated liver fat on circulating adipocytokines and insulin resistance in obese Hispanic adolescents
Q42559007Inhibitory effect of IL-8 on insulin action in human adipocytes via MAP kinase pathway
Q37344018Keratinocyte-derived chemokine in obesity: expression, regulation, and role in adipose macrophage infiltration and glucose homeostasis
Q42806798LPS response pattern of inflammatory adipokines in an in vitro 3T3-L1 murine adipocyte model
Q46970541Lysosomal dysfunction results in altered energy balance
Q28506501MCP-1 (monocyte chemotactic protein-1)-induced protein, a recently identified zinc finger protein, induces adipogenesis in 3T3-L1 pre-adipocytes without peroxisome proliferator-activated receptor gamma
Q38695289Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation.
Q44528933Macrophage inflammatory protein-related protein-2, a novel CC chemokine, can regulate preadipocyte migration and adipocyte differentiation
Q37470376Mechanisms of inflammatory responses and development of insulin resistance: how are they interlinked?
Q43889817Mediators of inflammation in children with type I diabetes mellitus: cytokines in type I diabetic children
Q40229345Mesenteric adipose tissue-derived monocyte chemoattractant protein-1 plays a crucial role in adipose tissue macrophage migration and activation in obese mice
Q28261153MicroRNA 132 regulates nutritional stress-induced chemokine production through repression of SirT1
Q35163496Monocyte chemoattractant protein 1 in obesity and insulin resistance
Q46806069Monocyte chemoattractant protein-1 and nitric oxide promote adipogenesis in a model that mimics obesity
Q51308595Monocyte chemoattractant protein-1 gene polymorphism and its serum level have an impact on anthropometric and biochemical risk factors of metabolic syndrome in Indian population.
Q79986532Monocyte chemoattractant protein-1 in obesity and type 2 diabetes. Insulin sensitivity study
Q47402154Monocyte chemoattractant protein-1 is produced in isolated adipocytes, associated with adiposity and reduced after weight loss in morbid obese subjects.
Q39969772Monocyte chemoattractant protein-1 secreted by adipose tissue induces direct lipid accumulation in hepatocytes
Q54567899Monocyte chemoattractant protein-1-induced tissue inflammation is critical for the development of renal injury but not type 2 diabetes in obese db/db mice.
Q35496179Neuropeptides, mesenteric fat, and intestinal inflammation
Q37861765Novel C-C chemokine receptor 2 antagonists in metabolic disease: a review of recent developments
Q58394437Obesity is associated with increased risks of prostate cancer metastasis and death after initial cancer diagnosis in middle-aged men
Q38298806Obesity-associated mouse adipose stem cell secretion of monocyte chemotactic protein-1.
Q33753336One size does not fit all in severe infection: obesity alters outcome, susceptibility, treatment, and inflammatory response
Q47183992Opposite regulation of interleukin-8 and tumor necrosis factor-alpha by weight loss
Q38084435Oxidative stress and the ageing endocrine system
Q36576544Pathways leading to muscle insulin resistance--the muscle--fat connection
Q37747052Peritoneal adipocytes and their role in inflammation during peritoneal dialysis
Q42580689Perspectives on adipose tissue, chagas disease and implications for the metabolic syndrome
Q42449940Pioglitazone reduces inflammatory responses of human adipocytes to factors secreted by monocytes/macrophages
Q33739936Polymorphisms in bovine immune genes and their associations with somatic cell count and milk production in dairy cattle.
Q36818315Prenatal fat-rich diet exposure alters responses of embryonic neurons to the chemokine, CCL2, in the hypothalamus
Q42797761Prostaglandin D2 and J2-series (PGJ2, Delta12-PGJ2) prostaglandins stimulate IL-6 and MCP-1, but inhibit leptin, expression and secretion by 3T3-L1 adipocytes
Q33627028Quercetin suppresses MIP-1α-induced adipose inflammation by downregulating its receptors CCR1/CCR5 and inhibiting inflammatory signaling
Q37998514Recent advances in the pathophysiology and pharmacological treatment of obesity
Q37105363Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response
Q38301003Reduced adiposity in ob/ob mice following total body irradiation and bone marrow transplantation
Q36666799Reduced albuminuria with sarpogrelate is accompanied by a decrease in monocyte chemoattractant protein-1 levels in type 2 diabetes
Q88380827Regenerative Potential and Inflammation-Induced Secretion Profile of Human Adipose-Derived Stromal Vascular Cells Are Influenced by Donor Variability and Prior Breast Cancer Diagnosis
Q73366753Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans
Q46583275Regulation of monocyte chemoattractant protein 1 (MCP-1) release by explants of human visceral adipose tissue
Q47896753Relation of chemokines to BMI and insulin resistance at ages 18-21.
Q38440408Relationship between adiponectin, obesity and insulin resistance
Q37846784Reliability of leptin, but not adiponectin, as a biomarker for diet-induced weight loss in humans
Q37009739Risk factors and mechanisms of non-alcoholic steatohepatitis
Q36863519Role of MCP-1 on inflammatory processes and metabolic dysfunction following high-fat feedings in the FVB/N strain
Q33784591Saturated fatty acids enhance osteoclast survival
Q37150835Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 deficiency reduces leukocyte infiltration into adipose tissue and favors fat deposition.
Q35039955Serum IL-1beta, IL-2, and IL-6 in insulin-dependent diabetic children
Q57420160Serum amyloid A: production by human white adipocyte and regulation by obesity and nutrition
Q47632254TLR signalling and adapter utilization in primary human in vitro differentiated adipocytes
Q35056023Targeting monocyte chemoattractant protein-1 signalling in disease
Q47215931The Diabetes Gene and Wnt Pathway Effector TCF7L2 Regulates Adipocyte Development and Function.
Q37991199The cellular and signaling networks linking the immune system and metabolism in disease
Q64883844The chemokine receptor CXCR2 contributes to murine adipocyte development.
Q36859053The usefulness of circulating adipokine levels for the assessment of obesity-related health problems
Q35762436The weight of leptin in immunity
Q81480642Tumor necrosis factor-alpha stimulates HIV-1 production in primary culture of human adipocytes
Q36297539Twenty years after ACEIs and ARBs: emerging treatment strategies for diabetic nephropathy
Q33654000Upregulated TNF Expression 1 Year After Bariatric Surgery Reflects a Cachexia-Like State in Subcutaneous Adipose Tissue
Q47176179YKL-40 is elevated in morbidly obese patients and declines after weight loss.
Q80761815Zymosan-induced inflammation stimulates neo-adipogenesis
Q33885235trans-10,cis-12-Conjugated linoleic acid instigates inflammation in human adipocytes compared with preadipocytes