Heterogeneity and complexity of native brain nicotinic receptors.

scientific article

Heterogeneity and complexity of native brain nicotinic receptors. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.BCP.2007.05.023
P698PubMed publication ID17597586

P50authorMichele ZoliQ42498009
P2093author name stringCecilia Gotti
Annalisa Gaimarri
Milena Moretti
Alessio Zanardi
Franceso Clementi
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectheterogeneityQ928498
P304page(s)1102-1111
P577publication date2007-06-02
P1433published inBiochemical PharmacologyQ864229
P1476titleHeterogeneity and complexity of native brain nicotinic receptors
P478volume74

Reverse relations

cites work (P2860)
Q43236757A conserved cysteine residue in the third transmembrane domain is essential for homomeric 5-HT3 receptor function
Q34846533A portable site: a binding element for 17β-estradiol can be placed on any subunit of a nicotinic α4β2 receptor
Q34172963A transcriptional regulatory element critical for CHRNB4 promoter activity in vivo
Q34458445Acetylcholine Receptor (AChR) α5 Subunit Variant Associated with Risk for Nicotine Dependence and Lung Cancer Reduces (α4β2)2α5 AChR Function
Q36807622Activation of the α7 nicotinic ACh receptor induces anxiogenic effects in rats which is blocked by a 5-HT₁a receptor antagonist
Q39061997Acute activation, desensitization and smoldering activation of human acetylcholine receptors
Q36573029Adolescent nicotine exposure transiently increases high-affinity nicotinic receptors and modulates inhibitory synaptic transmission in rat medial prefrontal cortex
Q34958405Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist.
Q27345275Alcohol and nicotine interactions: pre-clinical models of dependence
Q34078196Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells
Q24307995Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking
Q37125192Alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators.
Q92402680Alzheimer's Disease as a Membrane Disorder: Spatial Cross-Talk Among Beta-Amyloid Peptides, Nicotinic Acetylcholine Receptors and Lipid Rafts
Q37334917An ER-resident membrane protein complex regulates nicotinic acetylcholine receptor subunit composition at the synapse
Q35181919An autoradiographic survey of mouse brain nicotinic acetylcholine receptors defined by null mutants
Q33883659Association of CHRN genes with "dizziness" to tobacco
Q41636544Associations of rare nicotinic cholinergic receptor gene variants to nicotine and alcohol dependence
Q28477330Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations
Q46345641Brain activation by short-term nicotine exposure in anesthetized wild-type and beta2-nicotinic receptors knockout mice: a BOLD fMRI study.
Q36111331CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences
Q36973272Characterization of a multiple ligand-gated ion channel cellular membrane affinity chromatography column and identification of endogenously expressed receptors in astrocytoma cell lines
Q35117369Cholinergic modulation of angiogenesis: role of the 7 nicotinic acetylcholine receptor.
Q34139537Cholinergic modulation of neuronal excitability in the accessory olfactory bulb.
Q48609200Cognitive Effects of Nicotine: Recent Progress
Q30474904Cognitive effects of nicotine: genetic moderators
Q35181132Contributions of β2 subunit-containing nAChRs to chronic nicotine-induced alterations in cognitive flexibility in mice
Q48510136Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds
Q64074559Crystal Structure of the Monomeric Extracellular Domain of α9 Nicotinic Receptor Subunit in Complex With α-Conotoxin RgIA: Molecular Dynamics Insights Into RgIA Binding to α9α10 Nicotinic Receptors
Q43178185Demonstration of functional alpha4-containing nicotinic receptors in the medial habenula
Q34167942Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors
Q37995815Development of the motivational system during adolescence, and its sensitivity to disruption by nicotine.
Q37535489Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions
Q35108773Differential expression of the beta4 neuronal nicotinic receptor subunit affects tolerance development and nicotinic binding sites following chronic nicotine treatment
Q27676607Dimeric  -Cobratoxin X-ray Structure: LOCALIZATION OF INTERMOLECULAR DISULFIDES AND POSSIBLE MODE OF BINDING TO NICOTINIC ACETYLCHOLINE RECEPTORS
Q38204497Diverse strategies targeting α7 homomeric and α6β2* heteromeric nicotinic acetylcholine receptors for smoking cessation
Q36850568Effects of chronic buspirone treatment on nicotine and concurrent nicotine+cocaine self-administration
Q37642452Effects of chronic varenicline treatment on nicotine, cocaine, and concurrent nicotine+cocaine self-administration
Q33636887Engineering neuronal nicotinic acetylcholine receptors with functional sensitivity to alpha-bungarotoxin: a novel alpha3-knock-in mouse
Q37018495Epibatidine application in vitro blocks retinal waves without silencing all retinal ganglion cell action potentials in developing retina of the mouse and ferret
Q34458500Expression of Functional Human α6β2β3* Acetylcholine Receptors in Xenopus laevis Oocytes Achieved through Subunit Chimeras and Concatamers
Q28487793Fluorescence-based high-throughput functional profiling of ligand-gated ion channels at the level of single cells
Q33578294Functional characterization improves associations between rare non-synonymous variants in CHRNB4 and smoking behavior
Q46365543Functional expression of nicotinic acetylcholine receptors in rat neocortical layer 5 pyramidal cells
Q37150553Ganglionic acetylcholine receptor autoantibody: oncological, neurological, and serological accompaniments
Q48094212Imaging α4β2 Nicotinic Acetylcholine Receptors (nAChRs) in Baboons with [18F]XTRA, a Radioligand with Improved Specific Binding in Extra-Thalamic Regions.
Q38741215Impact of ageing on postsynaptic neuronal nicotinic neurotransmission in auditory thalamus
Q40954873Impact of human D398N single nucleotide polymorphism on intracellular calcium response mediated by α3β4α5 nicotinic acetylcholine receptors
Q44959002Impact of neuro-psychological factors on smoking-associated lung cancer
Q37326725In vivo effects of 3-iodocytisine: pharmacological and genetic analysis of hypothermia and evaluation of chronic treatment on nicotinic binding sites
Q40111690Insights into nicotinic receptor signaling in nicotine addiction: Implications for prevention and treatment.
Q89259836Knockout of alpha 5 nicotinic acetylcholine receptors subunit alters ethanol-mediated behavioral effects and reward in mice
Q50023885Layer- and Cell Type-Specific Modulation of Excitatory Neuronal Activity in the Neocortex
Q47177367Levamisole: A Positive Allosteric Modulator for the α3β4 Nicotinic Acetylcholine Receptors Prevents Weight Gain in the CD-1 Mice on a High Fat Diet
Q39850502Long-term nicotine treatment differentially regulates striatal alpha6alpha4beta2* and alpha6(nonalpha4)beta2* nAChR expression and function
Q92177749Minimal Structural Changes Determine Full and Partial Nicotinic Receptor Agonist Activity for Nicotine Analogues
Q37508580Modeling nicotinic neuromodulation from global functional and network levels to nAChR based mechanisms
Q36208114Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA.
Q35531867Molecular interaction of α-conotoxin RgIA with the rat α9α10 nicotinic acetylcholine receptor
Q22252514Multiple roles for nicotine in Parkinson's disease
Q35566709Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses
Q34342747Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence
Q36137598Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions
Q37381294Nicotine aversion: Neurobiological mechanisms and relevance to tobacco dependence vulnerability
Q37180827Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys
Q37294509Nicotine self-medication of cognitive-attentional processing
Q36851620Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation
Q48618313Nicotinic cholinergic and dopaminergic receptor mRNA expression in male and female rats with high or low preference for nicotine.
Q30372351Nicotinic ligands as multifunctional agents for the treatment of neuropsychiatric disorders
Q28087047Nicotinic receptor modulation to treat alcohol and drug dependence
Q38345699Nicotinic receptors and attention
Q36828916Nicotinic receptors in neurodegeneration
Q37590093Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system
Q39136644Orthosteric and allosteric potentiation of heteromeric neuronal nicotinic acetylcholine receptors
Q34661812Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats
Q37395740Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes
Q38193225Pharmacological chaperoning of nAChRs: a therapeutic target for Parkinson's disease.
Q35996739Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response.
Q28547248Positive Selection on Loci Associated with Drug and Alcohol Dependence
Q35873352Potentiation of Neuronal Nicotinic Receptors by 17β-Estradiol: Roles of the Carboxy-Terminal and the Amino-Terminal Extracellular Domains
Q37976289Prefrontal neuromodulation by nicotinic receptors for cognitive processes.
Q33938764Proteomic analysis of an alpha7 nicotinic acetylcholine receptor interactome
Q30392403R-(+) and S-(-) isomers of cotinine augment cholinergic responses in vitro and in vivo
Q42721778Radioligand binding characterization of neuronal nicotinic acetylcholine receptors
Q37148710Receptor and channel heteromers as pain targets
Q30395065Replicated Risk Nicotinic Cholinergic Receptor Genes for Nicotine Dependence
Q37187599Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release
Q30495752Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice
Q88561566Stoichiometry of the Heteromeric Nicotinic Receptors of the Renshaw Cell
Q34782188Structural answers and persistent questions about how nicotinic receptors work
Q33738559Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation.
Q33955964Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation.
Q55515264Synthesis, Structure and Biological Activity of CIA and CIB, Two α-Conotoxins from the Predation-Evoked Venom of Conus catus.
Q37916643Targeting nicotinic receptors for Parkinson's disease therapy
Q34359550Tethered Agonist Analogs as Site-Specific Probes for Domains of the Human α7 Nicotinic Acetylcholine Receptor that Differentially Regulate Activation and Desensitization
Q37942053The CHRNA5-A3-B4 gene cluster in nicotine addiction
Q51299120The E Loop of the Transmitter Binding Site Is a Key Determinant of the Modulatory Effects of Physostigmine on Neuronal Nicotinic α4β2 Receptors.
Q37021273The effect of prenatal nicotine on expression of nicotine receptor subunits in the fetal brain
Q35801503The effects of nicotine on the human electroretinogram
Q26821785The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function
Q34126960The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: dual role in nicotine addiction and lung cancer
Q37405388The nicotinic α5 subunit can replace either an acetylcholine-binding or nonbinding subunit in the α4β2* neuronal nicotinic receptor
Q38090678The potential of neuronal nicotinic acetylcholine receptor agonists for treating CNS conditions
Q38365379The role of nicotinic acetylcholine receptors in autosomal dominant nocturnal frontal lobe epilepsy
Q37789790The structural basis of function in Cys-loop receptors.
Q42472318The α2-subunit of the nicotinic cholinergic receptor is specifically expressed in medial subpallium-derived cells of mammalian amygdala
Q40392015The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse
Q34837643The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental area
Q30442195The β2 nicotinic acetylcholine receptor subunit differentially influences ethanol behavioral effects in the mouse
Q38525254Therapeutic conotoxins: a US patent literature survey
Q52590407Therapeutic potential of multifunctional tacrine analogues.
Q43265406Tonic modulation of GABA release by nicotinic acetylcholine receptors in layer V of the murine prefrontal cortex
Q38435927Unorthodox Acetylcholine Binding Sites Formed by α5 and β3 Accessory Subunits in α4β2* Nicotinic Acetylcholine Receptors
Q49335818Venom based neural modulators
Q45424062Young Human Cholinergic Neurons Respond to Physiological Regulators and Improve Cognitive Symptoms in an Animal Model of Alzheimer's Disease
Q37387341Zebrafish: a model for the study of addiction genetics
Q35186645Zinc-permeable ion channels: effects on intracellular zinc dynamics and potential physiological/pathophysiological significance
Q33349481alpha4beta2 Nicotinic acetylcholine receptors, willing if able
Q35588867α-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between α6β4 and α6β2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release
Q39287268α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition.
Q35264378α6β2* and α4β2* nicotinic acetylcholine receptors as drug targets for Parkinson's disease

Search more.