| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Eric A. Engleman | |
| Richard L. Bell | |||
| Shafiqur Rahman | |||
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| Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations | Q30405502 | ||
| A double-blind, placebo-controlled trial assessing the efficacy of varenicline tartrate for alcohol dependence | Q30412161 | ||
| Modulation of ethanol drinking-in-the-dark by mecamylamine and nicotinic acetylcholine receptor agonists in C57BL/6J mice | Q37467418 | ||
| Neuronal nicotinic acetylcholine receptors as pharmacotherapeutic targets for the treatment of alcohol use disorders | Q37473457 | ||
| The α5 neuronal nicotinic acetylcholine receptor subunit plays an important role in the sedative effects of ethanol but does not modulate consumption in mice | Q37514878 | ||
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| Massive withdrawal symptoms and affective vulnerability are associated with variants of the CHRNA4 gene in a subgroup of smokers | Q37534290 | ||
| Genetic variants in nicotine addiction and alcohol metabolism genes, oral cancer risk and the propensity to smoke and drink alcohol: a replication study in India | Q37558430 | ||
| Nicotine addiction and nicotinic receptors: lessons from genetically modified mice | Q37756527 | ||
| Cholinergic receptor system as a target for treating alcohol abuse and dependence | Q38009047 | ||
| Nicotinic acetylcholine receptors: from basic science to therapeutics | Q38038381 | ||
| Nicotinic receptors as therapeutic targets for drug addictive disorders | Q38097906 | ||
| Curious cases: Altered dose-response relationships in addiction genetics. | Q38159889 | ||
| The differential diagnosis of fetal alcohol spectrum disorder | Q38196791 | ||
| Antagonism of alpha 3 beta 4 nicotinic receptors as a strategy to reduce opioid and stimulant self-administration | Q40743432 | ||
| The pharmacology of galanthamine and its analogues | Q40971880 | ||
| Alternate stoichiometries of alpha4beta2 nicotinic acetylcholine receptors | Q41412933 | ||
| Hippocampal nicotinic autoreceptors modulate acetylcholine release | Q41556836 | ||
| Varenicline attenuates cue-induced relapse to alcohol, but not nicotine seeking, while reducing inhibitory response control. | Q41862387 | ||
| Inhibition of both alpha7* and beta2* nicotinic acetylcholine receptors is necessary to prevent development of sensitization to cocaine-elicited increases in extracellular dopamine levels in the ventral striatum | Q42497934 | ||
| The effects of a novel nicotinic receptor antagonist N,N-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) on acute and repeated nicotine-induced increases in extracellular dopamine in rat nucleus accumbens | Q42503949 | ||
| Nicotinic acetylcholine receptor genes on chromosome 15q25.1 are associated with nicotine and opioid dependence severity | Q42931523 | ||
| Nicotinic ligands modulate ethanol-induced dopamine function in mice. | Q42935961 | ||
| Varenicline and mecamylamine attenuate locomotor sensitization and cross-sensitization induced by nicotine and morphine in mice | Q43069598 | ||
| Sazetidine-A, a selective alpha4beta2 nicotinic receptor desensitizing agent and partial agonist, reduces nicotine self-administration in rats | Q43223190 | ||
| Possible association of nicotinic acetylcholine receptor gene (CHRNA4 and CHRNB2) polymorphisms with nicotine dependence in Japanese males: an exploratory study. | Q43478631 | ||
| Nicotinic receptor partial agonists modulate alcohol deprivation effect in C57BL/6J mice. | Q43659089 | ||
| Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas | Q43925474 | ||
| Mecamylamine modifies the pharmacokinetics and reinforcing effects of alcohol | Q43940291 | ||
| Central nervous system mechanisms in alcohol relapse | Q43966436 | ||
| Identification of the nicotinic receptor subtypes expressed on dopaminergic terminals in the rat striatum. | Q44185954 | ||
| Nicotine increases alcohol self-administration and reinstates alcohol seeking in rats | Q44283841 | ||
| Role of different nicotinic acetylcholine receptors in mediating behavioral and neurochemical effects of ethanol in mice | Q44292703 | ||
| Differential desensitization and distribution of nicotinic acetylcholine receptor subtypes in midbrain dopamine areas. | Q44418971 | ||
| Mecamylamine attenuates the subjective stimulant-like effects of alcohol in social drinkers | Q44453598 | ||
| Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice. | Q44904935 | ||
| The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine | Q45122619 | ||
| Mecamylamine and ethanol preference in healthy volunteers | Q45227006 | ||
| Blocking α4β2 and α7 nicotinic acetylcholine receptors inhibits the reinstatement of morphine-induced CPP by drug priming in mice | Q45370997 | ||
| Markers in the 15q24 nicotinic receptor subunit gene cluster (CHRNA5-A3-B4) predict severity of nicotine addiction and response to smoking cessation therapy. | Q45930766 | ||
| The role of the CHRNA4 gene in Internet addiction: a case-control study. | Q45972949 | ||
| Rivastigmine reduces tobacco craving in alcohol-dependent smokers. | Q46006310 | ||
| The smoking cessation medication varenicline attenuates alcohol and nicotine interactions in the rat mesolimbic dopamine system | Q46173380 | ||
| Effects of subunit selective nACh receptors on operant ethanol self-administration and relapse-like ethanol-drinking behavior | Q46261665 | ||
| Single nucleotide polymorphisms in CHRNA5 rs16969968, CHRNA3 rs578776, and LOC123688 rs8034191 are associated with heaviness of smoking in women in Northeastern Ontario, Canada | Q46325000 | ||
| Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats | Q46748775 | ||
| Contribution of dihydro-beta-erythroidine sensitive nicotinic acetylcholine receptors in the ventral tegmental area to cocaine-induced behavioral sensitization in rats | Q46824682 | ||
| Variant within the promoter region of the CHRNA3 gene associated with FTN dependence is not related to self-reported willingness to quit smoking | Q48140840 | ||
| The effects of lobeline on nicotine withdrawal-induced depression-like behavior in mice | Q48323897 | ||
| Stoichiometry and pharmacology of two human alpha4beta2 nicotinic receptor types | Q48326369 | ||
| Voluntary ethanol intake in the rat and the associated accumbal dopamine overflow are blocked by ventral tegmental mecamylamine | Q48346302 | ||
| alpha-conotoxin AuIB selectively blocks alpha3 beta4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release. | Q48368043 | ||
| Characterization of nicotinic receptor-mediated [3H]dopamine release from synaptosomes prepared from mouse striatum | Q48434978 | ||
| Decision-making deficits in drug addiction | Q48498708 | ||
| Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices | Q48541686 | ||
| The nicotinic acetylcholine receptor antagonist mecamylamine prevents escalation of cocaine self-administration in rats with extended daily access | Q48594630 | ||
| The alcohol deprivation effect in the alcohol-preferring P rat under free-drinking and operant access conditions | Q48714904 | ||
| Nicotine-induced inhibition in medial septum involves activation of presynaptic nicotinic cholinergic receptors on gamma-aminobutyric acid-containing neurons | Q49150686 | ||
| Cytisine modulates chronic voluntary ethanol consumption and ethanol-induced striatal up-regulation of ΔFosB in mice. | Q50190904 | ||
| Effects of chronic sazetidine-A, a selective α4β2 neuronal nicotinic acetylcholine receptors desensitizing agent on pharmacologically-induced impaired attention in rats. | Q50778512 | ||
| Varenicline and cytisine: two nicotinic acetylcholine receptor ligands reduce ethanol intake in University of Chile bibulous rats. | Q50877680 | ||
| Mecamylamine blockade of both positive and negative effects of IV nicotine in human volunteers. | Q51079328 | ||
| The nicotinic antagonist mecamylamine preferentially inhibits cocaine vs. food self-administration in rats. | Q51363792 | ||
| Long-term alcohol self-administration with repeated alcohol deprivation phases: an animal model of alcoholism? | Q51984492 | ||
| Involvement of nicotinic receptors in alcohol self-administration. | Q52170503 | ||
| Development of an alcohol deprivation and escalation effect in C57BL/6J mice. | Q52290305 | ||
| The polymorphism of the CHRNA5 gene and the strength of nicotine addiction in lung cancer and COPD patients. | Q52299483 | ||
| Neuronal nicotinic receptor ligands modulate chronic nicotine-induced ethanol consumption in C57BL/6J mice. | Q52301066 | ||
| Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment | Q71865726 | ||
| The mesolimbic dopamine-activating properties of ethanol are antagonized by mecamylamine | Q72723449 | ||
| Presynaptic nicotinic receptors modulating dopamine release in the rat striatum | Q73689125 | ||
| Lobeline and cytisine reduce voluntary ethanol drinking behavior in male C57BL/6J mice | Q82634100 | ||
| Association of nicotinic acetylcholine receptor subunit alpha-4 polymorphisms with smoking behaviors in Chinese male smokers | Q84526904 | ||
| Recent advances in understanding nicotinic receptor signaling mechanisms that regulate drug self-administration behavior. | Q35184641 | ||
| Relationship between CYP2A6 and CHRNA5-CHRNA3-CHRNB4 variation and smoking behaviors and lung cancer risk | Q35202104 | ||
| CHRNA3 rs1051730 genotype and short-term smoking cessation | Q35231050 | ||
| Effects of varenicline on the reinforcing and discriminative stimulus effects of cocaine in rhesus monkeys | Q35429740 | ||
| Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women | Q35473808 | ||
| Safety and efficacy of varenicline to reduce positive subjective effects produced by methamphetamine in methamphetamine-dependent volunteers | Q35580343 | ||
| New medications for substance use disorders: challenges and opportunities | Q35614182 | ||
| Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence. | Q35674705 | ||
| Smoking cessation pharmacogenetics: analysis of varenicline and bupropion in placebo-controlled clinical trials | Q35679980 | ||
| Results of an initial clinical trial of varenicline for the treatment of cocaine dependence | Q35685676 | ||
| Neurochemical and behavioral studies on ethanol and nicotine interactions | Q35690515 | ||
| Nicotinic acetylcholine receptors containing the α4 subunit modulate alcohol reward | Q35850223 | ||
| Release of [3H]-noradrenaline from rat hippocampal synaptosomes by nicotine: mediation by different nicotinic receptor subtypes from striatal [3H]-dopamine release | Q35873313 | ||
| Nicotine modulates alcohol-seeking and relapse by alcohol-preferring (P) rats in a time-dependent manner | Q35903781 | ||
| Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits | Q35972927 | ||
| Recent advances in animal models of alcohol craving and relapse | Q35974646 | ||
| Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions | Q36137598 | ||
| Galantamine, an acetylcholinesterase inhibitor and positive allosteric modulator of nicotinic acetylcholine receptors, attenuates nicotine taking and seeking in rats | Q36174102 | ||
| CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results | Q36188181 | ||
| Effects of the specific α4β2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice | Q36298187 | ||
| Medications development to treat alcohol dependence: a vision for the next decade | Q36357552 | ||
| Current and emerging pharmacotherapies for treating tobacco dependence | Q36580581 | ||
| Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system | Q36607367 | ||
| Longitudinal associations between smoking cessation medications and alcohol consumption among smokers in the International Tobacco Control Four Country survey | Q36724460 | ||
| Varenicline: new treatment with efficacy in smoking cessation | Q36758341 | ||
| Rationale, pharmacology and clinical efficacy of partial agonists of alpha4beta2 nACh receptors for smoking cessation | Q36850882 | ||
| A neurocognitive approach to understanding the neurobiology of addiction | Q36897597 | ||
| Fetal alcohol syndrome and the developing socio-emotional brain | Q36899319 | ||
| Effects of sazetidine-A, a selective alpha4beta2 nicotinic acetylcholine receptor desensitizing agent on alcohol and nicotine self-administration in selectively bred alcohol-preferring (P) rats | Q36963775 | ||
| Nominal association with CHRNA4 variants and nicotine dependence | Q37055419 | ||
| The alcohol deprivation effect in C57BL/6J mice is observed using operant self-administration procedures and is modulated by CRF-1 receptor signaling | Q37070964 | ||
| The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses | Q37094759 | ||
| CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in Alaska Native tobacco users. | Q37179322 | ||
| New findings on nicotine addiction and treatment. | Q37327402 | ||
| Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity | Q30447847 | ||
| Transgenic over expression of nicotinic receptor alpha 5, alpha 3, and beta 4 subunit genes reduces ethanol intake in mice. | Q30454907 | ||
| Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice | Q30475871 | ||
| Nicotinic receptor ligands reduce ethanol intake by high alcohol-drinking HAD-2 rats | Q30478324 | ||
| Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice. | Q30487079 | ||
| Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction | Q30491854 | ||
| Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, selectively decreases ethanol consumption and seeking | Q30502320 | ||
| The development and maintenance of drug addiction | Q30560436 | ||
| Mecamylamine attenuates cue-induced reinstatement of nicotine-seeking behavior in rats | Q33610442 | ||
| Varenicline reduces alcohol self-administration in heavy-drinking smokers | Q33825408 | ||
| Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence | Q33870433 | ||
| SNPs in CHRNA6 and CHRNB3 are associated with alcohol consumption in a nationally representative sample | Q33893659 | ||
| Dose-dependent attenuation of heroin self-administration with lobeline. | Q33958021 | ||
| Nicotinic mechanisms involved in the dopamine activating and reinforcing properties of ethanol | Q34002764 | ||
| Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption | Q34137278 | ||
| Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics | Q34157674 | ||
| AT-1001: a high affinity and selective α3β4 nicotinic acetylcholine receptor antagonist blocks nicotine self-administration in rats | Q34249682 | ||
| Varenicline decreases alcohol consumption in heavy-drinking smokers | Q34271996 | ||
| Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence | Q34342747 | ||
| Nicotinic receptor antagonists as treatments for nicotine abuse | Q34401397 | ||
| Neuronal nicotinic receptor alpha 6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain | Q34409926 | ||
| Sazetidine-A, a novel ligand that desensitizes alpha4beta2 nicotinic acetylcholine receptors without activating them | Q34549732 | ||
| Cytisine for the treatment of nicotine addiction: from a molecule to therapeutic efficacy. | Q34601430 | ||
| Varenicline effects on cocaine self administration and reinstatement behavior. | Q34616092 | ||
| Behavioral neurobiology of alcohol addiction: recent advances and challenges. | Q34616149 | ||
| Nicotinic alpha 7 receptors as a new target for treatment of cannabis abuse | Q34631254 | ||
| Heterogeneity and complexity of native brain nicotinic receptors. | Q34642688 | ||
| Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats | Q34661812 | ||
| Diversity of vertebrate nicotinic acetylcholine receptors | Q34812497 | ||
| Association of a variant in the CHRNA5-A3-B4 gene cluster region to heavy smoking in the Italian population | Q34873948 | ||
| Structural and functional diversity of native brain neuronal nicotinic receptors | Q34983875 | ||
| Desensitization of neuronal nicotinic receptors | Q35000275 | ||
| Varenicline, a partial agonist at neuronal nicotinic acetylcholine receptors, reduces nicotine-induced increases in 20% ethanol operant self-administration in Sprague-Dawley rats | Q35046256 | ||
| Associations of nicotine intake measures with CHRN genes in Finnish smokers | Q35148758 | ||
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | substance dependence | Q3378593 |
| drug dependence | Q3541786 | ||
| P304 | page(s) | 426 | |
| P577 | publication date | 2015-01-15 | |
| P1433 | published in | Frontiers in Neuroscience | Q2177807 |
| P1476 | title | Nicotinic receptor modulation to treat alcohol and drug dependence | |
| P478 | volume | 8 |
| Q28068256 | A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction |
| Q37200655 | African-specific variability in the acetylcholine muscarinic receptor M4: association with cocaine and heroin addiction |
| Q35982324 | Association of Common Polymorphisms in the Nicotinic Acetylcholine Receptor Alpha4 Subunit Gene with an Electrophysiological Endophenotype in a Large Population-Based Sample |
| Q36372867 | Critical needs in drug discovery for cessation of alcohol and nicotine polysubstance abuse |
| Q48018449 | DNA damage and oxidative stress induced by seizures are decreased by anticonvulsant and neuroprotective effects of lobeline, a candidate to treat alcoholism. |
| Q48930829 | Different Hypothalamic Nicotinic α7 Receptor Expression and Response to Low Nicotine Dose in Alcohol-Preferring and Alcohol-Avoiding Rats |
| Q52639267 | Differential regulation of alcohol taking and seeking by antagonism at α4β2 and α3β4 nAChRs. |
| Q37635751 | Genes and Alcohol Consumption: Studies with Mutant Mice |
| Q99634880 | In Silico Finding of Key Interaction Mediated α3β4 and α7 Nicotinic Acetylcholine Receptor Ligand Selectivity of Quinuclidine-Triazole Chemotype |
| Q64915913 | Inhibition of alpha7 nicotinic receptors in the ventral hippocampus selectively attenuates reinstatement of morphine-conditioned place preference and associated changes in AMPA receptor binding. |
| Q38686274 | Interactions between the endocannabinoid and nicotinic cholinergic systems: preclinical evidence and therapeutic perspectives |
| Q47942161 | Medications for alcohol use disorders: An overview |
| Q35974049 | Neuronal Nicotinic Acetylcholine Receptor Modulators Reduce Sugar Intake |
| Q35960331 | Nicotinic Mechanisms Modulate Ethanol Withdrawal and Modify Time Course and Symptoms Severity of Simultaneous Withdrawal from Alcohol and Nicotine |
| Q42368290 | Sophora alopecuroides L. var. alopecuroides alleviates morphine withdrawal syndrome in mice: involvement of alkaloid fraction and matrine |
| Q60923945 | The Prophylactic and Therapeutic Effects of Saffron Extract and Crocin on Ethanol Withdrawal Syndrome in Mice |
| Q64906665 | The α9α10 Nicotinic Acetylcholine Receptor Antagonist αO-Conotoxin GeXIVA[1,2] Alleviates and Reverses Chemotherapy-Induced Neuropathic Pain. |
| Q92070044 | UFR2709, a Nicotinic Acetylcholine Receptor Antagonist, Decreases Ethanol Intake in Alcohol-Preferring Rats |
| Q42004188 | Varying Chirality Across Nicotinic Acetylcholine Receptor Subtypes: Selective Binding of Quinuclidine Triazole Compounds |
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