| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1035909322 |
| P356 | DOI | 10.1007/BF02245149 |
| P698 | PubMed publication ID | 1615127 |
| P2093 | author name string | P B Clarke | |
| K B Franklin | |||
| W A Corrigall | |||
| K M Coen | |||
| P2860 | cites work | Persistent behavior at high rates maintained by intravenous self-administration of nicotine. | Q52292036 |
| Evidence that mesolimbic dopaminergic activation underlies the locomotor stimulant action of nicotine in rats | Q70398932 | ||
| Clinical evaluation of mecamylamine for withdrawal from nicotine dependence | Q70499378 | ||
| Stereospecific nicotine receptors on rat brain membranes | Q71379781 | ||
| Nicotine action on rat colon | Q72468284 | ||
| A comparison of nicotine and cocaine self-administration in the dog: fixed-ratio and progressive-ratio schedules of intravenous drug infusion. | Q34270844 | ||
| Immunohistochemical localization of a neuronal nicotinic acetylcholine receptor in mammalian brain | Q34374159 | ||
| Brain dopamine and reward | Q34498922 | ||
| Chronic central nicotinic blockade after a single administration of the bisquaternary ganglion-blocking drug chlorisondamine | Q36004090 | ||
| Nicotinic receptor blockade therapy and smoking cessation | Q37206584 | ||
| Understanding brain mechanisms in nicotine reinforcement | Q37206596 | ||
| 6-Hydroxydopamine lesions of the medial prefrontal cortex fail to influence intravenous self-administration of cocaine. | Q41245321 | ||
| Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis | Q41351009 | ||
| Effect of nigrostriatal dopamine depletion on the post-training, memory-improving action of amphetamine | Q41389351 | ||
| Abuse liability and pharmacodynamic characteristics of intravenous and inhaled nicotine | Q41500106 | ||
| Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats | Q41573401 | ||
| Locomotor activity in rats after administration of nicotinic agonists intracerebrally | Q41876237 | ||
| Characterization of the locomotor stimulant action of nicotine in tolerant rats | Q41904004 | ||
| Nicotinic excitation of rat ventral tegmental neurones in vitro studied by intracellular recording | Q42009955 | ||
| Nicotine cue in rats: effects of central administration of ganglion-blocking drugs | Q42249010 | ||
| Distribution of alpha 2, alpha 3, alpha 4, and beta 2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat. | Q44234396 | ||
| Nicotine maintains robust self-administration in rats on a limited-access schedule | Q44290531 | ||
| Immunohistochemical localization of neuronal nicotinic receptors in the rodent central nervous system | Q46184511 | ||
| Anatomical analysis of the involvement of mesolimbocortical dopamine in the locomotor stimulant actions of d-amphetamine and apomorphine | Q48151345 | ||
| Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats | Q48264505 | ||
| Chlorisondamine blocks acquisition of the conditioned taste aversion produced by (-)-nicotine. | Q48302013 | ||
| Selective 6OHDA-induced destruction of mesolimbic dopamine neurons: abolition of psychostimulant-induced locomotor activity in rats | Q48351909 | ||
| Autoradiographic evidence for nicotine receptors on nigrostriatal and mesolimbic dopaminergic neurons | Q48428303 | ||
| Microinjections of a nicotinic agonist into dopamine terminal fields: effects on locomotion | Q48904603 | ||
| Locomotion induced by ventral tegmental microinjections of a nicotinic agonist | Q49067208 | ||
| Nicotine indirectly inhibits [3H]dopamine uptake at concentrations that do not directly promote [3H]dopamine release in rat striatum. | Q51717181 | ||
| Maintenance of schedule-controlled behavior by intravenous injections of nicotine in squirrel monkeys. | Q51858467 | ||
| Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens. | Q51876339 | ||
| Selective dopamine antagonists reduce nicotine self-administration. | Q52238695 | ||
| P433 | issue | 2-3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | dopamine | Q170304 |
| P304 | page(s) | 285-289 | |
| P577 | publication date | 1992-01-01 | |
| P1433 | published in | Psychopharmacology | Q1422802 |
| P1476 | title | The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine | |
| P478 | volume | 107 |
| Q52191627 | (-)-Nornicotine partially substitutes for (+)-amphetamine in a drug discrimination paradigm in rats. |
| Q47972966 | 5-[I-125/123]lodo-3(2(S)-azetidinylmethoxy)pyridine, a radioiodinated analog of A-85380 for in vivo studies of central nicotinic acetylcholine receptors |
| Q34633132 | A DRD1 polymorphism predisposes to lung cancer among those exposed to secondhand smoke during childhood |
| Q48394205 | A double-blind placebo controlled experimental study of nicotine: I--effects on incentive motivation |
| Q34068084 | A genetically modulated, intrinsic cingulate circuit supports human nicotine addiction |
| Q37266119 | A mechanistic hypothesis of the factors that enhance vulnerability to nicotine use in females |
| Q45942528 | A neurotensin analog, NT69L, attenuates intravenous nicotine self-administration in rats |
| Q34527972 | A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse |
| Q37365090 | A positive relationship between harm avoidance and brain nicotinic acetylcholine receptor availability |
| Q37081416 | A psychobiological framework of the substrates that mediate nicotine use during adolescence |
| Q39544975 | A simple physiologically based pharmacokinetic model evaluating the effect of anti-nicotine antibodies on nicotine disposition in the brains of rats and humans |
| Q43857751 | A study of the nicotinic agonist SIB-1553A on locomotion and attention as measured by the five-choice serial reaction time task |
| Q34052455 | A tobacco reconceptualization in psychiatry: toward the development of tobacco-free psychiatric facilities |
| Q28589593 | Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine |
| Q52272017 | Activation of dopamine D1 receptors or alpha 1 adrenoceptors is not involved in the EEG effect of nicotine in rats. |
| Q90395863 | Acute and Chronic Nicotine Exposures Differentially Affect Central Serotonin 2A Receptor Function: Focus on the Lateral Habenula |
| Q42522832 | Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections |
| Q34035775 | Acute effects of nicotine amplify accumbal neural responses during nicotine-taking behavior and nicotine-paired environmental cues |
| Q28263613 | Acute nicotine induces anxiety and disrupts temporal pattern organization of rat exploratory behavior in hole-board: a potential role for the lateral habenula |
| Q46754805 | Acute risperidone treatment did not increase daily cigarette consumption or plasma levels of cotinine and caffeine: a pilot study |
| Q37246024 | Addiction and dose response: the psychomotor stimulant theory of addiction reveals that hormetic dose responses are dominant |
| Q34266602 | Administration of the nicotinic acetylcholine receptor agonists ABT-089 and ABT-107 attenuates the reinstatement of nicotine-seeking behavior in rats. |
| Q37363808 | Age dependent nicotinic influences over dopamine neuron synaptic plasticity |
| Q44739804 | Age-dependent effects of nicotine on locomotor activity and conditioned place preference in rats |
| Q35174622 | Age-related changes in nicotine response of cholinergic and non-cholinergic laterodorsal tegmental neurons: implications for the heightened adolescent susceptibility to nicotine addiction |
| Q30493138 | Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors in the nucleus accumbens shell regulate progressive ratio responding maintained by nicotine |
| Q34717418 | Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. |
| Q43094420 | Alteration of intravenous nicotine self-administration by opioid receptor agonist and antagonists in rats |
| Q33933548 | Alteration of the behavioral effects of nicotine by chronic caffeine exposure. |
| Q33525534 | Amphetamine administration into the ventral striatum facilitates behavioral interaction with unconditioned visual signals in rats |
| Q38839642 | An overview of alcohol and tobacco/nicotine interactions in the human laboratory |
| Q74545898 | Analgesia and abuse potential: an accidental association or a common substrate? |
| Q40422963 | Angiotensin AT1 and AT2 receptor antagonists modulate nicotine-evoked [³H]dopamine and [³H]norepinephrine release |
| Q38044592 | Association between dopamine receptor 2 TaqIA polymorphisms and smoking behavior with an influence of ethnicity: a systematic review and meta-analysis update |
| Q37085367 | Astrocytic control of synaptic transmission and plasticity: a target for drugs of abuse? |
| Q94052431 | Astrocytic hypertrophy in the rat ventral tegmental area following chronic morphine differs with age |
| Q48139910 | Bifeprunox: a partial agonist at dopamine D2 and serotonin 1A receptors, influences nicotine-seeking behaviour in response to drug-associated stimuli in rats |
| Q42022968 | Biological basis of tobacco addiction: Implications for smoking-cessation treatment |
| Q35209437 | Biological mechanisms underlying the relationship between stress and smoking: state of the science and directions for future work |
| Q41764058 | Bis-azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation |
| Q35679955 | Blockade of dopamine d4 receptors attenuates reinstatement of extinguished nicotine-seeking behavior in rats |
| Q44295864 | Blockade of mesolimbic dopamine transmission dramatically increases sensitivity to the rewarding effects of nicotine in the ventral tegmental area |
| Q52177843 | Blockade of nicotine self-administration with nicotinic antagonists in rats. |
| Q42702701 | Blockade of nicotinic receptor-mediated release of dopamine from striatal synaptosomes by chlorisondamine administered in vivo |
| Q42146107 | Blockade of nicotinic receptor-mediated release of dopamine from striatal synaptosomes by chlorisondamine and other nicotinic antagonists administered in vitro |
| Q27312497 | Blunted striatal responses to favorite-food cues in smokers |
| Q48650560 | Both nicotinic and muscarinic receptors in ventral tegmental area contribute to brain-stimulation reward |
| Q47381358 | Brain substrates of early (4h) cigarette abstinence: Identification of treatment targets. |
| Q52171874 | Brain-stimulation reward thresholds raised by an antisense oligonucleotide for the M5 muscarinic receptor infused near dopamine cells. |
| Q47918544 | Bumetanide blocks the acquisition of conditioned fear in adult rats. |
| Q37247103 | Cellular events in nicotine addiction |
| Q34498016 | Cellular mechanisms of nicotine addiction |
| Q36812599 | Cholinergic connectivity: it's implications for psychiatric disorders. |
| Q35945918 | Chromosome 15q25 (CHRNA3-CHRNB4) Variation Indirectly Impacts Lung Cancer Risk in Chinese Males |
| Q52040990 | Chronic haloperidol administration does not block acute nicotine-induced improvements in radial-arm maze performance in the rat. |
| Q35209160 | Chronic nicotine pretreatment is sufficient to upregulate α4* nicotinic receptors and increase oral nicotine self-administration in mice |
| Q42443864 | Co-expression of alpha7 and beta2 nicotinic acetylcholine receptor subunit mRNAs within rat brain cholinergic neurons |
| Q33942653 | Co-morbidity of smoking in patients with psychiatric and substance use disorders |
| Q30396291 | Cognitive deficits in schizophrenia: focus on neuronal nicotinic acetylcholine receptors and smoking |
| Q30474904 | Cognitive effects of nicotine: genetic moderators |
| Q48405808 | Common aspects of the action of nicotine and other drugs of abuse |
| Q31002871 | Common substrates of dysphoria in stimulant drug abuse and primary depression: therapeutic targets |
| Q44069082 | Comparative effects of methamphetamine and nicotine on the striatal [(11)C]raclopride binding in unanesthetized monkeys |
| Q36293008 | Complex interactions between nicotine and nonpharmacological stimuli reveal multiple roles for nicotine in reinforcement. |
| Q42698437 | Complexity of VTA DA neural activities in response to PFC transection in nicotine treated rats. |
| Q43852515 | Concomitant clozapine reduces smoking in patients treated with risperidone |
| Q30505379 | Conditioned response evoked by nicotine conditioned stimulus preferentially induces c-Fos expression in medial regions of caudate-putamen. |
| Q46512608 | Contextual stimuli modulate extinction and reinstatement in rodents self-administering intravenous nicotine |
| Q34444549 | Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking |
| Q43832288 | Contributory role for nornicotine in nicotine neuropharmacology: nornicotine-evoked [3H]dopamine overflow from rat nucleus accumbens slices |
| Q46870975 | Coptidis Rhizoma attenuates repeated nicotine-induced behavioural sensitization in the rat. |
| Q44552618 | Cortisol as an indicator of dopaminergic effects on nicotine craving |
| Q33894614 | Could a common biochemical mechanism underlie addictions? |
| Q35947872 | DAT genotype modulates brain and behavioral responses elicited by cigarette cues. |
| Q37389482 | DRD2-related TaqIA polymorphism modulates motivation to smoke. |
| Q42369697 | Desensitization of the nicotine-induced mesolimbic dopamine responses during constant infusion with nicotine |
| Q36063653 | Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons |
| Q44418971 | Differential desensitization and distribution of nicotinic acetylcholine receptor subtypes in midbrain dopamine areas. |
| Q36184313 | Discovery of a novel nicotinic receptor antagonist for the treatment of nicotine addiction: 1-(3-Picolinium)-12-triethylammonium-dodecane dibromide (TMPD). |
| Q43614893 | Disruption of dopaminergic neurotransmission in nucleus accumbens core inhibits the locomotor stimulant effects of nicotine and D-amphetamine in rats |
| Q73434121 | Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats |
| Q37103329 | Divergent functional effects of sazetidine-a and varenicline during nicotine withdrawal. |
| Q38204497 | Diverse strategies targeting α7 homomeric and α6β2* heteromeric nicotinic acetylcholine receptors for smoking cessation |
| Q33751420 | Dopamine D₂ and acetylcholine α7 nicotinic receptors have subcellular distributions favoring mediation of convergent signaling in the mouse ventral tegmental area |
| Q44171253 | Dopamine agonist and antagonist responders as related to types of nicotine craving and facets of extraversion |
| Q42948457 | Dopamine receptor blockade modulates the rewarding and aversive properties of nicotine via dissociable neuronal activity patterns in the nucleus accumbens |
| Q24681363 | Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. |
| Q37821386 | Dopamine signaling in the nucleus accumbens of animals self-administering drugs of abuse |
| Q34726771 | Dorsal as well as ventral striatal lesions affect levels of intravenous cocaine and morphine self-administration in rats |
| Q48405857 | Drug-activation of brain reward pathways |
| Q44658283 | Dynamic increases in dopamine during paced copulation in the female rat |
| Q46748775 | Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats |
| Q46776466 | Effect of ginseng saponins on enhanced dopaminergic transmission and locomotor hyperactivity induced by nicotine |
| Q47798409 | Effect of nicotine use and withdrawal on brain preproenkephalin A mRNA. |
| Q46701762 | Effect of sustained-release (SR) bupropion on craving and withdrawal in smokers deprived of cigarettes for 72 h. |
| Q48307117 | Effect of ventral tegmental 6-hydroxydopamine lesions on the locomotor stimulant action of nicotine in rats |
| Q71943026 | Effects of acute D-CPPene on mesoaccumbens dopamine responses to nicotine in the rat |
| Q44525598 | Effects of acute nicotine on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain |
| Q51866498 | Effects of bupropion on the reinstatement of nicotine-induced conditioned place preference by drug priming in rats. |
| Q53751185 | Effects of chronic oral nicotine treatment and its withdrawal on locomotor activity and brain monoamines in mice. |
| Q73713403 | Effects of cotinine at cholinergic nicotinic receptors of the sympathetic superior cervical ganglion of the mouse |
| Q33786352 | Effects of dopamine antagonists on drug cue-induced reinstatement of nicotine-seeking behavior in rats |
| Q47628965 | Effects of nicotine and amphetamine on latent inhibition in human subjects |
| Q38819551 | Effects of nicotine and chlorisondamine on cerebral glucose utilization in immobilized and freely-moving rats |
| Q36899798 | Effects of nicotine on emotional distraction of attentional orienting: evidence of possible moderation by dopamine type 2 receptor genotype. |
| Q38381191 | Effects of nicotine on novelty detection and memory recognition performance: double-blind, placebo-controlled studies of smokers and nonsmokers. |
| Q48374416 | Effects of nornicotine enantiomers on intravenous S(-)-nicotine self-administration and cardiovascular function in rats |
| Q48400218 | Effects of repeated nicotine pre-treatment on mesoprefrontal dopaminergic and behavioral responses to acute footshock stress |
| Q48165192 | Effects of smoking successive low- and high-nicotine cigarettes on hypothalamic-pituitary-adrenal axis hormones and mood in men. |
| Q37121061 | Effects of the nicotinic receptor partial agonists varenicline and cytisine on the discriminative stimulus effects of nicotine in rats |
| Q43136266 | Effects of varenicline and mecamylamine on the acquisition, expression, and reinstatement of nicotine-conditioned place preference by drug priming in rats |
| Q37094785 | Effects of varenicline on smoking cue–triggered neural and craving responses |
| Q48500578 | Elementary particles for models of drug dependence, 10th Okey Memorial Lecture presented at the Institute of Psychiatry, London on 19th March 1997. |
| Q89099639 | Emotion recognition and its relation to prefrontal function and network in heroin plus nicotine dependence: a pilot study |
| Q48453177 | Endocrine effects of nicotine administration, tobacco and other drug withdrawal in humans |
| Q52274686 | Endocrine responses during acute nicotine withdrawal. |
| Q43857748 | Enhanced motor activity and brain dopamine turnover in mice during long-term nicotine administration in the drinking water |
| Q37347476 | Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes |
| Q48099176 | Enhancement of sensitization to nicotine-induced ambulatory stimulation by psychological stress in rats |
| Q37500457 | Environmental smoking and smoking onset in adolescence: the role of dopamine-related genes. Findings from two longitudinal studies |
| Q44410731 | Ethanol elevates accumbal dopamine levels via indirect activation of ventral tegmental nicotinic acetylcholine receptors |
| Q80778386 | Examining the clinical efficacy of bupropion and nortriptyline as smoking cessation agents in a rodent model of nicotine withdrawal |
| Q22251269 | Exercise as a novel treatment for drug addiction: a neurobiological and stage-dependent hypothesis |
| Q36274171 | Exposure to nicotine and sensitization of nicotine-induced behaviors |
| Q43882948 | Expression of neuronal nicotinic acetylcholine receptor subunit mRNAs within midbrain dopamine neurons |
| Q36299535 | Forebrain substrates of reward and motivation |
| Q37602515 | From smoking to lung cancer: the CHRNA5/A3/B4 connection |
| Q33875395 | Functional brain imaging of tobacco use and dependence |
| Q36816827 | Functional characterization of AT-1001, an α3β4 nicotinic acetylcholine receptor ligand, at human α3β4 and α4β2 nAChR |
| Q37327514 | Functional implications of glutamatergic projections to the ventral tegmental area |
| Q33865234 | Gene variants of brain dopamine pathways and smoking-induced dopamine release in the ventral caudate/nucleus accumbens |
| Q51846775 | Gene-environment interaction in problematic substance use: interaction between DRD4 and insecure attachments. |
| Q37264547 | Genetic variation in the dopamine pathway and smoking cessation |
| Q34969212 | Genetically expressed HIV-1 viral proteins attenuate nicotine-induced behavioral sensitization and alter mesocorticolimbic ERK and CREB signaling in rats. |
| Q30491854 | Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction |
| Q28369941 | Ginseng total saponin inhibits nicotine-induced hyperactivity and conditioned place preference in mice |
| Q34816555 | Habenular α5 nicotinic receptor subunit signalling controls nicotine intake |
| Q46477695 | Haplotype analysis indicates an association between the DOPA decarboxylase (DDC) gene and nicotine dependence. |
| Q35353532 | Historical and current perspective on tobacco use and nicotine addiction |
| Q34643948 | Hormones, nicotine, and cocaine: clinical studies |
| Q42615631 | How Intravenous Nicotine Administration in Smokers Can Inform Tobacco Regulatory Science |
| Q30441131 | How can we use our knowledge of alcohol-tobacco interactions to reduce alcohol use? |
| Q37520732 | Hypocretin mechanisms in nicotine addiction: evidence and speculation |
| Q73184561 | Ibogaine and the dopaminergic response to nicotine |
| Q37331804 | Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse |
| Q33946922 | In vivo brain imaging of human exposure to nicotine and tobacco |
| Q30663528 | In vivo imaging of nicotinic receptor upregulation following chronic (-)-nicotine treatment in baboon using SPECT. |
| Q33751118 | In vivo pharmacology of endocannabinoids and their metabolic inhibitors: therapeutic implications in Parkinson's disease and abuse liability |
| Q34390965 | Inbred mouse strains vary in oral self-selection of nicotine |
| Q48825425 | Increased striatal dopamine efflux follows scopolamine administered systemically or to the tegmental pedunculopontine nucleus |
| Q33836376 | Indolizidine (-)-235B' and related structural analogs: discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [3H]dopamine release |
| Q48389447 | Influence of tetrodotoxin and calcium on changes in extracellular dopamine levels evoked by systemic nicotine |
| Q28481710 | Intense passionate love attenuates cigarette cue-reactivity in nicotine-deprived smokers: an FMRI study |
| Q38686274 | Interactions between the endocannabinoid and nicotinic cholinergic systems: preclinical evidence and therapeutic perspectives |
| Q42707905 | Intraneuronal accumulation and persistence of radiolabel in rat brain following in vivo administration of [3H]-chlorisondamine |
| Q30451390 | Intravenous gestational nicotine exposure results in increased motivation for sucrose reward in adult rat offspring |
| Q34543525 | Intrinsic membrane properties and synaptic inputs regulating the firing activity of the dopamine neurons. |
| Q42565570 | Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity |
| Q34558819 | Involvement of serotonin in nicotine dependence: processes relevant to positive and negative regulation of drug intake |
| Q52182848 | Is dopamine important in nicotine dependence? |
| Q36666651 | It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood |
| Q44333473 | Kappa-opioid receptor modulation of nicotine-induced behaviour |
| Q48364549 | Ligands selective for alpha4beta2 but not alpha3beta4 or alpha7 nicotinic receptors generalise to the nicotine discriminative stimulus in the rat. |
| Q73109552 | Lobeline inhibits nicotine-evoked [(3)H]dopamine overflow from rat striatal slices and nicotine-evoked (86)Rb(+) efflux from thalamic synaptosomes |
| Q42468426 | Local perfusion of nicotine differentially modulates somatodendritic dopamine release in the rat ventral tegmental area after nicotine preexposure |
| Q42708564 | Locomotor activation and dopamine release produced by nicotine and isoarecolone in rats |
| Q44176715 | Locomotor stimulant effects of nornicotine: role of dopamine |
| Q37384621 | Long-term nicotine treatment down-regulates α6β2* nicotinic receptor expression and function in nucleus accumbens |
| Q36955591 | Long-term upregulation of protein kinase A and adenylate cyclase levels in human smokers. |
| Q43648899 | Low-level lead exposure modulates effects of quinpirole and eticlopride on response rates in a fixed-interval schedule |
| Q31970663 | Measurement of plasma metabolites of (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine (5-IA-85380), a nicotinic acetylcholine receptor imaging agent, in nonhuman primates |
| Q41814331 | Mecamylamine but not the alpha7 receptor antagonist alpha-bungarotoxin blocks sensitization to the locomotor stimulant effects of nicotine |
| Q44149166 | Mecamylamine decreases accumbal dopamine output in mice treated chronically with nicotine |
| Q43349394 | Mecamylamine effects on haloperidol-induced catalepsy and defecation |
| Q37018610 | Mechanism-based medication development for the treatment of nicotine dependence. |
| Q35894576 | Mechanisms for multiple activity modes of VTA dopamine neurons |
| Q37519956 | Mechanisms underlying the comorbidity of tobacco use in mental health and addictive disorders |
| Q37079797 | Medications Development for the Treatment of Nicotine Dependence in Individuals with Schizophrenia |
| Q33620754 | Metabolic hormones, dopamine circuits, and feeding |
| Q35291239 | Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) microinfusions into the nucleus accumbens shell or ventral tegmental area attenuate the reinforcing effects of nicotine in rats |
| Q37147049 | Methylphenidate enhances the abuse-related behavioral effects of nicotine in rats: intravenous self-administration, drug discrimination, and locomotor cross-sensitization |
| Q44080843 | Modulation of nicotine self-administration in rats by combination therapy with agents blocking alpha 3 beta 4 nicotinic receptors |
| Q73689530 | Modulatory effect of ginseng total saponin on dopamine release and tyrosine hydroxylase gene expression induced by nicotine in the rat |
| Q40986707 | Molecular and cellular aspects of nicotine abuse |
| Q26851972 | Molecular mechanisms underlying behaviors related to nicotine addiction |
| Q37327392 | Molecular mechanisms underlying the motivational effects of nicotine |
| Q90603824 | More than Smoke and Patches: The Quest for Pharmacotherapies to Treat Tobacco Use Disorder |
| Q37125141 | NMDA receptors regulate nicotine-enhanced brain reward function and intravenous nicotine self-administration: role of the ventral tegmental area and central nucleus of the amygdala |
| Q51122395 | Naltrexone, smoking behaviour and cigarette withdrawal. |
| Q35566709 | Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses |
| Q33772059 | Neuroadaptive changes associated with smoking: structural and functional neural changes in nicotine dependence |
| Q41619079 | Neuroadaptive changes in the mesocortical glutamatergic system during chronic nicotine self-administration and after extinction in rats |
| Q91991315 | Neurobiological and Neurophysiological Mechanisms Underlying Nicotine Seeking and Smoking Relapse |
| Q34390258 | Neurobiology of addiction |
| Q34498032 | Neurobiology of the nicotine withdrawal syndrome |
| Q42705902 | Neurochemical and behavioural interactions between ibogaine and nicotine in the rat. |
| Q34578530 | Neuronal nicotinic acetylcholine receptor subunit knockout mice: physiological and behavioral phenotypes and possible clinical implications. |
| Q34342747 | Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence |
| Q36137598 | Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions |
| Q36376434 | Neuropharmacology and potential efficacy of new treatments for tobacco dependence |
| Q34637004 | Neurophysiology of Nicotine Addiction |
| Q44880443 | Neuroscience of addiction |
| Q58183149 | Nicotine Self-Administration in Animals: A Reevaluation |
| Q48451777 | Nicotine addiction and the lure of reward |
| Q43186230 | Nicotine administration stimulates the in vivo N-methyl-D-aspartate receptor/nitric oxide/cyclic GMP pathway in rat hippocampus through glutamate release |
| Q41835696 | Nicotine and cocaine self-administration using a multiple schedule of intravenous drug and sucrose reinforcement in rats |
| Q35748436 | Nicotine and ethanol co-use in Long-Evans rats: Stimulatory effects of perinatal exposure to a fat-rich diet |
| Q47775155 | Nicotine and food induced dopamine release in the nucleus accumbens of the rat: putative role of alpha7 nicotinic receptors in the ventral tegmental area |
| Q36345893 | Nicotine and nonnicotine factors in cigarette addiction |
| Q37381294 | Nicotine aversion: Neurobiological mechanisms and relevance to tobacco dependence vulnerability |
| Q49723355 | Nicotine drug discrimination and nicotinic acetylcholine receptors in differentially reared rats |
| Q37216830 | Nicotine exposure during adolescence induces a depression-like state in adulthood |
| Q43198953 | Nicotine hapten structure, antibody selectivity and effect relationships: results from a nicotine vaccine screening procedure |
| Q46937479 | Nicotine increases dopamine clearance in medial prefrontal cortex in rats raised in an enriched environment |
| Q35893691 | Nicotine increases dopamine transporter function in rat striatum through a trafficking-independent mechanism |
| Q48366302 | Nicotine modifies the activity of ventral tegmental area dopaminergic neurons and hippocampal GABAergic neurons |
| Q46459290 | Nicotine normalizes increased prefrontal cortical dopamine D1 receptor binding and decreased working memory performance produced by repeated pretreatment with MK-801: a PET study in conscious monkeys |
| Q35846864 | Nicotine persistently activates ventral tegmental area dopaminergic neurons via nicotinic acetylcholine receptors containing α4 and α6 subunits |
| Q43125451 | Nicotine provokes impulsive-like action by stimulating alpha4beta2 nicotinic acetylcholine receptors in the infralimbic, but not in the prelimbic cortex |
| Q45763902 | Nicotine reinforcement is reduced by cannabinoid CB1 receptor blockade in the ventral tegmental area. |
| Q30244252 | Nicotine self-administration research: the legacy of Steven R. Goldberg and implications for regulation, health policy, and research |
| Q46544579 | Nicotine sensitization in adult male and female rats quinpirole-primed as neonates |
| Q36987118 | Nicotine vaccines to assist with smoking cessation: current status of research |
| Q43557493 | Nicotine-induced behavioral sensitization is associated with extracellular dopamine release and expression of c-Fos in the striatum and nucleus accumbens of the rat. |
| Q44126618 | Nicotine-induced conditioned place preference in adolescent and adult rats |
| Q44847053 | Nicotine-induced dopamine release in the nucleus accumbens is inhibited by the novel AMPA antagonist ZK200775 and the NMDA antagonist CGP39551. |
| Q38299405 | Nicotine-induced enhancement of glutamatergic and GABAergic synaptic transmission in the mouse amygdala. |
| Q45032449 | Nicotine-induced enhancement of responding for conditioned reinforcement in rats: role of prior nicotine exposure and α4β2 nicotinic receptors |
| Q52220497 | Nicotine-induced place preferences following prior nicotine exposure in rats. |
| Q37525085 | Nicotine-induced upregulation of nicotinic receptors: underlying mechanisms and relevance to nicotine addiction |
| Q41741650 | Nicotine: abused substance and therapeutic agent. |
| Q28550433 | Nicotinic Activity of Arecoline, the Psychoactive Element of "Betel Nuts", Suggests a Basis for Habitual Use and Anti-Inflammatory Activity |
| Q44620915 | Nicotinic Receptor Modulation of Dopamine Transporter Function in Rat Striatum and Medial Prefrontal Cortex |
| Q40444567 | Nicotinic Receptors and Cholinergic Neurotransmission in the Central Nervous System |
| Q33894536 | Nicotinic acetylcholine receptor knockout mice as animal models for studying receptor function |
| Q26824360 | Nicotinic acetylcholine receptor ligands, a patent review (2006-2011) |
| Q34761238 | Nicotinic acetylcholine receptors as targets for antidepressants. |
| Q43279623 | Nicotinic antagonist effects on functional attention networks |
| Q48618313 | Nicotinic cholinergic and dopaminergic receptor mRNA expression in male and female rats with high or low preference for nicotine. |
| Q35541262 | Nicotinic cholinergic synaptic mechanisms in the ventral tegmental area contribute to nicotine addiction |
| Q34401397 | Nicotinic receptor antagonists as treatments for nicotine abuse |
| Q28087047 | Nicotinic receptor modulation to treat alcohol and drug dependence |
| Q37518024 | Nicotinic receptor-based therapeutics and candidates for smoking cessation |
| Q37404292 | Nicotinic receptors and stages of nicotine dependence. |
| Q33763401 | Nicotinic receptors in the brain: correlating physiology with function |
| Q43846372 | Nornicotine, a nicotine metabolite and tobacco alkaloid: desensitization of nicotinic receptor-stimulated dopamine release from rat striatum |
| Q37259323 | Nucleus accumbens CREB activity is necessary for nicotine conditioned place preference |
| Q61949146 | Operant Ethanol Self-Administration After Nicotine Treatment and Withdrawal |
| Q44458252 | Operant responding for a visual reinforcer in rats is enhanced by noncontingent nicotine: implications for nicotine self-administration and reinforcement |
| Q48429046 | Operant responding for conditioned and unconditioned reinforcers in rats is differentially enhanced by the primary reinforcing and reinforcement-enhancing effects of nicotine |
| Q36708951 | Overview of the pharmacogenomics of cigarette smoking |
| Q37423361 | Oxytocin, motivation and the role of dopamine |
| Q37664482 | Partial nicotinic acetylcholine (alpha4beta2) agonists as promising new medications for smoking cessation |
| Q51439014 | Periadolescent nicotine exposure reduces cocaine reward in adult mice. |
| Q37304747 | Peroxisome proliferator-activated receptor (PPAR) agonists as promising new medications for drug addiction: preclinical evidence |
| Q93007144 | Persistent attenuation of nicotine self-administration in rats by co-administration of chronic nicotine infusion with the dopamine D1 receptor antagonist SCH-23390 or the serotonin 5-HT2C agonist lorcaserin |
| Q42126606 | Persistent nicotinic blockade by chlorisondamine of noradrenergic neurons in rat brain and cultured PC12 cells |
| Q35022995 | Pharmacogenetics of smoking cessation in general practice: results from the patch II and patch in practice trials |
| Q37395740 | Pharmacogenetics of smoking cessation: role of nicotine target and metabolism genes |
| Q90583753 | Pharmacological Effects and Regulatory Mechanisms of Tobacco Smoking Effects on Food Intake and Weight Control |
| Q40955351 | Pharmacology of nicotine and its therapeutic use in smoking cessation and neurodegenerative disorders |
| Q60637555 | Pharmakologische Strategien zur Unterstützung einer Raucherentwöhnung |
| Q45188899 | Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area. |
| Q27021772 | Preclinical evidence that activation of mesolimbic alpha 6 subunit containing nicotinic acetylcholine receptors supports nicotine addiction phenotype |
| Q42488958 | Preferential increase of extracellular dopamine in the rat nucleus accumbens shell as compared to that in the core during acquisition and maintenance of intravenous nicotine self-administration |
| Q41103326 | Presynaptic ionotropic receptors |
| Q37014100 | Presynaptic nicotinic receptors: a dynamic and diverse cholinergic filter of striatal dopamine neurotransmission |
| Q34398910 | Primary reinforcing effects of nicotine are triggered from multiple regions both inside and outside the ventral tegmental area |
| Q34322263 | Prior exposure to THC increases the addictive effects of nicotine in rats. |
| Q30494110 | Progressive and lasting amplification of accumbal nicotine-seeking neural signals |
| Q44100450 | Prolonged stimulation of presynaptic nicotinic acetylcholine receptors in the rat interpeduncular nucleus has differential effects on transmitter release |
| Q34400233 | Protection genes in nucleus accumbens shell affect vulnerability to nicotine self-administration across isogenic strains of adolescent rat |
| Q43823224 | Rats prefer cocaine over nicotine in a two-lever self-administration choice test. |
| Q35184641 | Recent advances in understanding nicotinic receptor signaling mechanisms that regulate drug self-administration behavior. |
| Q48317236 | Receptor systems participating in nicotine-specific effects |
| Q48528650 | Reduced dopamine output in the nucleus accumbens but not in the medial prefrontal cortex in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome |
| Q24792017 | Reduced inhibitory action of a GABAB receptor agonist on [3H]-dopamine release from rat ventral tegmental area in vitro after chronic nicotine administration |
| Q36484647 | Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo |
| Q43620612 | Regional cerebral blood flow effects of nicotine in overnight abstinent smokers |
| Q48725622 | Regional variation in the effects of nicotine on catecholamine overflow in rat brain |
| Q42370644 | Regulation of nicotinic receptors in rat brain following quasi-irreversible nicotinic blockade by chlorisondamine and chronic treatment with nicotine |
| Q50624456 | Relationship between tobacco and cannabis use status in outpatients with schizophrenia. |
| Q42972130 | Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release |
| Q42650652 | Repeated nicotine treatment in rats with high versus low rearing activity: analyses of behavioural sensitisation and place preference |
| Q48453186 | Response of the hypothalamo-pituitary-adrenal axis to nicotine |
| Q37024161 | Review. Neurobiology of nicotine dependence |
| Q59292055 | Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings |
| Q30462673 | Reward processing in autism: a thematic series |
| Q28214622 | Rewarding effects of the cholinergic agents carbachol and neostigmine in the posterior ventral tegmental area |
| Q33707660 | Right prefrontal activity reflects the ability to overcome sleepiness during working memory tasks: a functional near-infrared spectroscopy study |
| Q35121761 | Risk-taking behavior in adolescent mice: psychobiological determinants and early epigenetic influence. |
| Q34002770 | Role of alpha7 nicotinic receptors in nicotine dependence and implications for psychiatric illness |
| Q44292703 | Role of different nicotinic acetylcholine receptors in mediating behavioral and neurochemical effects of ethanol in mice |
| Q33894548 | Role of dopamine in the behavioural actions of nicotine related to addiction |
| Q35216481 | Role of the endogenous cannabinoid system in nicotine addiction: novel insights |
| Q50647796 | Role of α4- and α6-containing nicotinic receptors in the acquisition and maintenance of nicotine self-administration. |
| Q35690145 | Role of α6 nicotinic receptors in CNS dopaminergic function: relevance to addiction and neurological disorders |
| Q33939461 | Route of nicotine administration influences in vivo dopamine neuron activity: habituation, needle injection, and cannula infusion |
| Q48469856 | Sensitization of the mesoaccumbens dopamine response to nicotine |
| Q73614654 | Serotonin-1A antagonists attenuate the effects of nicotine withdrawal on the auditory startle response |
| Q36004637 | Sex differences in conditioned nicotine reward are age-specific |
| Q41808597 | Sex differences in neurotensin and substance P following nicotine self-administration in rats. |
| Q46881158 | Significant association of catechol-O-methyltransferase (COMT) haplotypes with nicotine dependence in male and female smokers of two ethnic populations. |
| Q37295878 | Smoking behaviour and mental health disorders--mutual influences and implications for therapy |
| Q35630902 | Smoking cessation and chronic pain: patient and pain medicine physician attitudes |
| Q36021541 | Smoking cessation behaviors three months following acute insular damage from stroke |
| Q34700539 | Smoking-specific parenting and smoking onset in adolescence: the role of genes from the dopaminergic system (DRD2, DRD4, DAT1 genotypes). |
| Q34618962 | Stress-sensitive neurosignalling in depression: an integrated network biology approach to candidate gene selection for genetic association analysis. |
| Q48184972 | Studies on the influence of nicotine infusions on mesolimbic dopamine and locomotor responses to nicotine |
| Q44147749 | Study of brain uptake and biodistribution of [11C]toluene in non-human primates and mice |
| Q30487079 | Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice. |
| Q37593350 | Synthesis and activity of substituted heteroaromatics as positive allosteric modulators for α4β2α5 nicotinic acetylcholine receptors |
| Q33738559 | Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation. |
| Q33955964 | Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation. |
| Q48250201 | Synthesis of an I-123 analog of A-85380 and preliminary SPECT imaging of nicotinic receptors in baboon |
| Q36786609 | Systems level neuroplasticity in drug addiction |
| Q34953245 | Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence |
| Q42324184 | Tetrakis-azaaromatic quaternary ammonium salts: novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release |
| Q35837700 | The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse control |
| Q36335083 | The detrimental danger of Water-Pipe (Hookah) transcends the hazardous consequences of general health to the driving behavior |
| Q83745548 | The effects of nicotine exposure and PFC transection on the time-frequency distribution of VTA DA neurons' firing activities |
| Q33933562 | The effects of nicotine on neural pathways implicated in depression: a factor in nicotine addiction? |
| Q41052058 | The effects of the mGluR5 receptor antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) on behavioural responses to nicotine |
| Q34730787 | The epidemiology of smoking: health consequences and benefits of cessation |
| Q40938769 | The incentive amplifying effects of nicotine are reduced by selective and non-selective dopamine antagonists in rats |
| Q42259547 | The influence of lobeline on nucleus accumbens dopamine and locomotor responses to nicotine in nicotine-pretreated rats |
| Q37276928 | The influence of mecamylamine on ethanol and sucrose self-administration |
| Q44304048 | The motivational valence of nicotine in the rat ventral tegmental area is switched from rewarding to aversive following blockade of the alpha7-subunit-containing nicotinic acetylcholine receptor |
| Q34988448 | The necessity of α4* nicotinic receptors in nicotine-driven behaviors: dissociation between reinforcing and motor effects of nicotine |
| Q35621339 | The neurobiology of nicotine addiction: bridging the gap from molecules to behaviour |
| Q44519057 | The nicotinic alpha 4 beta 2 receptor selective agonist, TC-2559, increases dopamine neuronal activity in the ventral tegmental area of rat midbrain slices |
| Q41963353 | The novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide decreases nicotine-induced dopamine metabolism in rat nucleus accumbens |
| Q73572188 | The pedunculopontine tegmental nucleus and the role of cholinergic neurons in nicotine self-administration in the rat: a correlative neuroanatomical and behavioral study |
| Q42284404 | The pharmacology of the nicotinic antagonist, chlorisondamine, investigated in rat brain and autonomic ganglion |
| Q34002757 | The putative role of extra-synaptic mesolimbic dopamine in the neurobiology of nicotine dependence |
| Q46809457 | The rewarding effect of aggression is reduced by nucleus accumbens dopamine receptor antagonism in mice |
| Q30491487 | The role of NMDA receptor antagonists in nicotine tolerance, sensitization, and physical dependence: a preclinical review |
| Q37416390 | The role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal |
| Q40480641 | The role of dopamine in drug abuse viewed from the perspective of its role in motivation |
| Q38338790 | The role of mesoaccumbens dopamine in nicotine dependence |
| Q40510452 | The scientific case that nicotine is addictive. |
| Q37066079 | The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions |
| Q36933882 | The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum |
| Q34837643 | The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental area |
| Q34444437 | Tobacco dependence, the insular cortex and the hypocretin connection |
| Q74496852 | Tobacco smoke influence on heart rate, body temperature, and locomotor activity daily rhythms as assessed by radiotelemetry in rats |
| Q47808957 | Tobacco smoking, genes, and dopamine |
| Q43825597 | Topiramate selectively attenuates nicotine-induced increases in monoamine release |
| Q52276428 | Transgenic mice in drug dependence research. |
| Q36906670 | Translational research in medication development for nicotine dependence |
| Q44245940 | Treating nicotine dependence during pregnancy and postpartum: understanding clinician knowledge and performance. |
| Q38274740 | Tris-azaaromatic quaternary ammonium salts: Novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release |
| Q30739506 | Ultrastructural localization of the alpha4-subunit of the neuronal acetylcholine nicotinic receptor in the rat substantia nigra. |
| Q89858108 | Unexpected loss of sensitivity to the nicotinic acetylcholine receptor antagonist activity of mecamylamine and dihydro-β-erythroidine in nicotine-tolerant mice |
| Q41619159 | Upregulation of ionotropic glutamate receptor subunits within specific mesocorticolimbic regions during chronic nicotine self-administration |
| Q34553486 | Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration |
| Q41405373 | Varenicline enhances dopamine release facilitation more than nicotine after long-term nicotine treatment and withdrawal |
| Q28576280 | Varenicline is a potent partial agonist at α6β2* nicotinic acetylcholine receptors in rat and monkey striatum |
| Q36798993 | Varenicline-Induced Elevation of Dopamine in Smokers: A Preliminary [(11)C]-(+)-PHNO PET Study. |
| Q37422715 | Ventral striatal dopamine release in response to smoking a regular vs a denicotinized cigarette |
| Q30411127 | Ventral striatum/nucleus accumbens activation to smoking-related pictorial cues in smokers and nonsmokers: a functional magnetic resonance imaging study |
| Q46618419 | Voluntary ethanol intake increases extracellular acetylcholine levels in the ventral tegmental area in the rat. |
| Q45078539 | Why do schizophrenic patients smoke? |
| Q34919642 | bPiDI: a novel selective α6β2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse |
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