| Q39942665 | 3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs |
| Q34109947 | 86Rb+ efflux mediated by alpha4beta2*-nicotinic acetylcholine receptors with high and low-sensitivity to stimulation by acetylcholine display similar agonist-induced desensitization |
| Q37081416 | A psychobiological framework of the substrates that mediate nicotine use during adolescence |
| Q37200239 | A role for α4(non-α6)* nicotinic acetylcholine receptors in motor behavior |
| Q40879665 | Accentuated behavioral sensitization to nicotine in the neonatal ventral hippocampal lesion model of schizophrenia |
| Q34304101 | Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior |
| Q34984038 | Acid-sensitive ionic channels in midbrain dopamine neurons are sensitive to ammonium, which may contribute to hyperammonemia damage |
| Q41913001 | Acquired appetitive responding to intravenous nicotine reflects a Pavlovian conditioned association. |
| Q34219378 | Acute ethanol inhibits dopamine release in the nucleus accumbens via α6 nicotinic acetylcholine receptors |
| Q35182062 | Acute in vivo nicotine administration enhances synchrony among dopamine neurons |
| Q48141419 | Acute nicotine increases both impulsive choice and behavioural disinhibition in rats |
| Q33939531 | Addictive nicotine alters local circuit inhibition during the induction of in vivo hippocampal synaptic potentiation |
| Q37363808 | Age dependent nicotinic influences over dopamine neuron synaptic plasticity |
| Q35174622 | Age-related changes in nicotine response of cholinergic and non-cholinergic laterodorsal tegmental neurons: implications for the heightened adolescent susceptibility to nicotine addiction |
| Q40586327 | Agonist-dependence of recovery from desensitization of P2X(3) receptors provides a novel and sensitive approach for their rapid up or downregulation |
| Q34717418 | Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. |
| Q35837691 | Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia |
| Q40101234 | Altered nicotine reward-associated behavior following α4 nAChR subunit deletion in ventral midbrain |
| Q36900018 | Animal models of nicotine exposure: relevance to second-hand smoking, electronic cigarette use, and compulsive smoking. |
| Q44699098 | Assembly of alpha4beta2 nicotinic acetylcholine receptors assessed with functional fluorescently labeled subunits: effects of localization, trafficking, and nicotine-induced upregulation in clonal mammalian cells and in cultured midbrain neurons. |
| Q30488629 | Atomoxetine reverses nicotine withdrawal-associated deficits in contextual fear conditioning |
| Q48332007 | Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys |
| Q41820628 | Behavioral and neural substrates of habit formation in rats intravenously self-administering nicotine. |
| Q41012076 | Bupropion and nicotine enhance responding for nondrug reinforcers via dissociable pharmacological mechanisms in rats. |
| Q36103496 | Bupropion dose-dependently reverses nicotine withdrawal deficits in contextual fear conditioning |
| Q61640485 | Calcium rises induced by AMPA and nicotine receptors in the ventral tegmental area show differences in mouse brain slices prenatally exposed to nicotine |
| Q35182023 | Characterizing functional α6β2 nicotinic acetylcholine receptors in vitro: mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells |
| Q33730490 | Cholinergic modulation of non-N-methyl-D-aspartic acid glutamatergic transmission in the chick ventral lateral geniculate nucleus |
| Q26991451 | Cholinergic modulation of the medial prefrontal cortex: the role of nicotinic receptors in attention and regulation of neuronal activity |
| Q42516910 | Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path. |
| Q37454529 | Chronic nicotine selectively enhances alpha4beta2* nicotinic acetylcholine receptors in the nigrostriatal dopamine pathway. |
| Q34132700 | Cocaine inhibition of nicotinic acetylcholine receptors influences dopamine release |
| Q48609200 | Cognitive Effects of Nicotine: Recent Progress |
| Q30474904 | Cognitive effects of nicotine: genetic moderators |
| Q36293008 | Complex interactions between nicotine and nonpharmacological stimuli reveal multiple roles for nicotine in reinforcement. |
| Q28472422 | Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference |
| Q37268138 | Controls of tonic and phasic dopamine transmission in the dorsal and ventral striatum. |
| Q26744123 | Crucial roles of the CHRNB3-CHRNA6 gene cluster on chromosome 8 in nicotine dependence: update and subjects for future research |
| Q36879193 | Cytisine, a Partial Agonist of α4β2 Nicotinic Acetylcholine Receptors, Reduced Unpredictable Chronic Mild Stress-Induced Depression-Like Behaviors |
| Q28506631 | Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit |
| Q34017006 | Developmental excitation of corticothalamic neurons by nicotinic acetylcholine receptors |
| Q36063653 | Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons |
| Q88386876 | Differential Control of Dopaminergic Excitability and Locomotion by Cholinergic Inputs in Mouse Substantia Nigra |
| Q37535489 | Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions |
| Q48388878 | Differential effects of nicotinic antagonists perfused into the nucleus accumbens or the ventral tegmental area on cocaine-induced dopamine release in the nucleus accumbens of mice |
| Q46220422 | Distinctive nicotinic acetylcholine receptor functional phenotypes of rat ventral tegmental area dopaminergic neurons |
| Q43263076 | Donepezil modulates nicotinic receptors of substantia nigra dopaminergic neurones |
| Q33751420 | Dopamine D₂ and acetylcholine α7 nicotinic receptors have subcellular distributions favoring mediation of convergent signaling in the mouse ventral tegmental area |
| Q24681363 | Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. |
| Q28084459 | Dopaminergic and cholinergic learning mechanisms in nicotine addiction |
| Q39011217 | Double target concept for smoking cessation |
| Q45245240 | Drug discrimination analysis of NMDA receptor channel blockers as nicotinic receptor antagonists in rats. |
| Q34013689 | Drugs of abuse and stress impair LTP at inhibitory synapses in the ventral tegmental area. |
| Q34211245 | Dynamic regulation of midbrain dopamine neuron activity: intrinsic, synaptic, and plasticity mechanisms |
| Q37196970 | Effectiveness of extended-duration transdermal nicotine therapy: a randomized trial |
| Q43136266 | Effects of varenicline and mecamylamine on the acquisition, expression, and reinstatement of nicotine-conditioned place preference by drug priming in rats |
| Q44472573 | Electrophysiological changes in laterodorsal tegmental neurons associated with prenatal nicotine exposure: implications for heightened susceptibility to addict to drugs of abuse |
| Q34961709 | Endogenous cholinergic inputs and local circuit mechanisms govern the phasic mesolimbic dopamine response to nicotine. |
| Q34001781 | Endogenous signaling through alpha7-containing nicotinic receptors promotes maturation and integration of adult-born neurons in the hippocampus |
| Q27687624 | Ethanol action on dopaminergic neurons in the ventral tegmental area: interaction with intrinsic ion channels and neurotransmitter inputs |
| Q84786849 | Exposure of nicotine to ventral tegmental area slices induces glutamatergic synaptic plasticity on dopamine neurons |
| Q30691545 | Factors modulating neural reactivity to drug cues in addiction: a survey of human neuroimaging studies |
| Q36106792 | Functional Upregulation of α4* Nicotinic Acetylcholine Receptors in VTA GABAergic Neurons Increases Sensitivity to Nicotine Reward |
| Q42525257 | Functional alpha7-containing nicotinic acetylcholine receptors localize to cell bodies and proximal dendrites in the rat substantia nigra pars reticulata |
| Q35794531 | Functional diversity of ventral midbrain dopamine and GABAergic neurons |
| Q34847679 | Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons |
| Q55529800 | GABAergic Neurons as Putative Neurochemical Substrate Mediating Aversive Effects of Nicotine. |
| Q35847720 | GABAergic actions mediate opposite ethanol effects on dopaminergic neurons in the anterior and posterior ventral tegmental area |
| Q54205394 | Gene Editing Vectors for Studying Nicotinic Acetylcholine Receptors in Cholinergic Transmission. |
| Q46510757 | Hypocretin and nicotine excite the same thalamocortical synapses in prefrontal cortex: correlation with improved attention in rat. |
| Q36451065 | Impact of prefrontal cortex in nicotine-induced excitation of ventral tegmental area dopamine neurons in anesthetized rats |
| Q34387101 | In vitro and in vivo characterization of a novel negative allosteric modulator of neuronal nAChRs |
| Q34158916 | In vitro identification and electrophysiological characterization of dopamine neurons in the ventral tegmental area |
| Q24643170 | In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors |
| Q35951334 | Increased nicotinic receptor desensitization in hypoglossal motor neurons following chronic developmental nicotine exposure |
| Q35017223 | Individual differences in oral nicotine intake in rats |
| Q27010347 | Inside-out neuropharmacology of nicotinic drugs |
| Q30448803 | Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations |
| Q37916772 | Intrinsic and integrative properties of substantia nigra pars reticulata neurons |
| Q33353989 | Intrinsically low open probability of α7 nicotinic acetylcholine receptors can be overcome by positive allosteric modulation and serum factors leading to the generation of excitotoxic currents at physiological temperatures |
| Q36666651 | It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood |
| Q46807409 | Layer-specific interference with cholinergic signaling in the prefrontal cortex by smoking concentrations of nicotine |
| Q42468426 | Local perfusion of nicotine differentially modulates somatodendritic dopamine release in the rat ventral tegmental area after nicotine preexposure |
| Q28513200 | Long-term effects of chronic nicotine exposure on brain nicotinic receptors |
| Q35117588 | Ly6h regulates trafficking of alpha7 nicotinic acetylcholine receptors and nicotine-induced potentiation of glutamatergic signaling |
| Q24647069 | Mammalian nicotinic acetylcholine receptors: from structure to function |
| Q37018610 | Mechanism-based medication development for the treatment of nicotine dependence. |
| Q28539236 | Mechanisms of metabonomic for a gateway drug: nicotine priming enhances behavioral response to cocaine with modification in energy metabolism and neurotransmitter level |
| Q27687645 | Mechanistic insights into nicotine withdrawal |
| Q36870245 | Mesolimbic dopamine and habenulo-interpeduncular pathways in nicotine withdrawal |
| Q37467418 | Modulation of ethanol drinking-in-the-dark by mecamylamine and nicotinic acetylcholine receptor agonists in C57BL/6J mice |
| Q30489625 | Modulation of hippocampus-dependent learning and synaptic plasticity by nicotine |
| Q26851972 | Molecular mechanisms underlying behaviors related to nicotine addiction |
| Q37327392 | Molecular mechanisms underlying the motivational effects of nicotine |
| Q27008063 | Molecules and circuits involved in nicotine addiction: The many faces of smoking |
| Q37219461 | Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes |
| Q90288996 | Neural circuits and nicotinic acetylcholine receptors mediate the cholinergic regulation of midbrain dopaminergic neurons and nicotine dependence |
| Q60046151 | Neurobiological Determinants of Tobacco Smoking in Schizophrenia |
| Q91991315 | Neurobiological and Neurophysiological Mechanisms Underlying Nicotine Seeking and Smoking Relapse |
| Q26782610 | Neuronal Nicotinic Acetylcholine Receptor Structure and Function and Response to Nicotine |
| Q36137598 | Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions |
| Q34637004 | Neurophysiology of Nicotine Addiction |
| Q48601283 | Neuroplasticity in cigarette smokers is altered under withdrawal and partially restituted by nicotine exposition. |
| Q36555854 | Nicotine Modifies Corticostriatal Plasticity and Amphetamine Rewarding Behaviors in Mice(1,2,3). |
| Q36298360 | Nicotine addiction and comorbidity with alcohol abuse and mental illness |
| Q30488043 | Nicotine and hippocampus-dependent learning: implications for addiction |
| Q35216455 | Nicotine as a modulator of behavior: beyond the inverted U. |
| Q37128659 | Nicotine decreases ethanol-induced dopamine signaling and increases self-administration via stress hormones |
| Q48212999 | Nicotine disrupts safety learning by enhancing fear associated with a safety cue via the dorsal hippocampus |
| Q40626831 | Nicotine is highly effective at producing desensitization of rat alpha4beta2 neuronal nicotinic receptors. |
| Q37728103 | Nicotine modulates GABAergic transmission to dopaminergic neurons in substantia nigra pars compacta |
| Q35846864 | Nicotine persistently activates ventral tegmental area dopaminergic neurons via nicotinic acetylcholine receptors containing α4 and α6 subunits |
| Q37525085 | Nicotine-induced upregulation of nicotinic receptors: underlying mechanisms and relevance to nicotine addiction |
| Q34797496 | Nicotine-mediated activation of dopaminergic neurons in distinct regions of the ventral tegmental area |
| Q44620915 | Nicotinic Receptor Modulation of Dopamine Transporter Function in Rat Striatum and Medial Prefrontal Cortex |
| Q55364105 | Nicotinic Restoration of Excitatory Neuroplasticity Is Linked to Improved Implicit Motor Learning Skills in Deprived Smokers. |
| Q37346923 | Nicotinic acetylcholine receptors containing the α6 subunit contribute to ethanol activation of ventral tegmental area dopaminergic neurons |
| Q37629127 | Nicotinic acetylcholine receptors in attention circuitry: the role of layer VI neurons of prefrontal cortex. |
| Q37387682 | Nicotinic activation of laterodorsal tegmental neurons: implications for addiction to nicotine |
| Q37439216 | Nicotinic and opioid receptor regulation of striatal dopamine D2-receptor mediated transmission |
| Q35541262 | Nicotinic cholinergic synaptic mechanisms in the ventral tegmental area contribute to nicotine addiction |
| Q33830478 | Nicotinic mechanisms influencing synaptic plasticity in the hippocampus |
| Q30993631 | Nicotinic modulation of neuronal networks: from receptors to cognition |
| Q37533310 | Nicotinic modulation of synaptic transmission and plasticity in cortico-limbic circuits |
| Q24532028 | Nicotinic receptor mechanisms and cognition in normal states and neuropsychiatric disorders |
| Q28087047 | Nicotinic receptor modulation to treat alcohol and drug dependence |
| Q35142884 | Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus |
| Q38345699 | Nicotinic receptors and attention |
| Q37582322 | Nicotinic receptors, amyloid-beta, and synaptic failure in Alzheimer's disease |
| Q48097853 | PPARα regulates cholinergic-driven activity of midbrain dopamine neurons via a novel mechanism involving α7 nicotinic acetylcholine receptors. |
| Q36052452 | Potential state-selective hydrogen bond formation can modulate activation and desensitization of the α7 nicotinic acetylcholine receptor |
| Q34359231 | Potential substrates for nicotine and alcohol interactions: a focus on the mesocorticolimbic dopamine system |
| Q34526371 | Preclinical Pharmacology, Efficacy and Safety of Varenicline in Smoking Cessation and Clinical Utility in High Risk Patients |
| Q37014100 | Presynaptic nicotinic receptors: a dynamic and diverse cholinergic filter of striatal dopamine neurotransmission |
| Q48120412 | Presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus. |
| Q46135988 | Properties of distinct ventral tegmental area synapses activated via pedunculopontine or ventral tegmental area stimulation in vitro. |
| Q36484647 | Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo |
| Q36906265 | Regulation of synaptic transmission and plasticity by neuronal nicotinic acetylcholine receptors |
| Q34768885 | Repeated exposure to methamphetamine causes long-lasting presynaptic corticostriatal depression that is renormalized with drug readministration |
| Q34173418 | Reward, addiction, withdrawal to nicotine |
| Q37314383 | Selective inhibition of acetylcholine-evoked responses of alpha7 neuronal nicotinic acetylcholine receptors by novel tris- and tetrakis-azaaromatic quaternary ammonium antagonists |
| Q45245208 | Sex differences in the contribution of nicotine and nonpharmacological stimuli to nicotine self-administration in rats. |
| Q30504498 | Smoke extracts and nicotine, but not tobacco extracts, potentiate firing and burst activity of ventral tegmental area dopaminergic neurons in mice |
| Q28506626 | Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice |
| Q34987300 | Targeting nicotine addiction: the possibility of a therapeutic vaccine. |
| Q37916643 | Targeting nicotinic receptors for Parkinson's disease therapy |
| Q34953245 | Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence |
| Q37028098 | The Sensory Impact of Nicotine on Noradrenergic and Dopaminergic Neurons of the Nicotine Reward - Addiction Neurocircuitry |
| Q37629917 | The effect of alcohol and nicotine abuse on gene expression in the brain |
| Q46575771 | The effects of DHBE and MLA on nicotine-induced enhancement of contextual fear conditioning in C57BL/6 mice |
| Q35621339 | The neurobiology of nicotine addiction: bridging the gap from molecules to behaviour |
| Q26830298 | The role of alpha-7 nicotinic receptors in food intake behaviors |
| Q34837643 | The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental area |
| Q90165538 | Transcranial Direct Current Stimulation Applied to the Dorsolateral and Ventromedial Prefrontal Cortices in Smokers Modifies Cognitive Circuits Implicated in the Nicotine Withdrawal Syndrome |
| Q37195457 | Varenicline ameliorates nicotine withdrawal-induced learning deficits in C57BL/6 mice |
| Q37092934 | Ventral tegmental area α6β2 nicotinic acetylcholine receptors modulate phasic dopamine release in the nucleus accumbens core |
| Q37230417 | Withdrawal from chronic nicotine administration impairs contextual fear conditioning in C57BL/6 mice |
| Q36335567 | α-Conotoxin PeIA[S9H,V10A,E14N] potently and selectively blocks α6β2β3 versus α6β4 nicotinic acetylcholine receptors |
| Q37422769 | α4α6β2* nicotinic acetylcholine receptor activation on ventral tegmental area dopamine neurons is sufficient to stimulate a depolarizing conductance and enhance surface AMPA receptor function |
| Q36517174 | α4β2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief |
| Q48355252 | α6 subunit-containing nicotinic receptors mediate low-dose ethanol effects on ventral tegmental area neurons and ethanol reward |
| Q35264378 | α6β2* and α4β2* nicotinic acetylcholine receptors as drug targets for Parkinson's disease |