| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1015142793 |
| P356 | DOI | 10.1038/37120 |
| P698 | PubMed publication ID | 9389479 |
| P5875 | ResearchGate publication ID | 13839553 |
| P2093 | author name string | Williams JT | |
| Dani JA | |||
| Pidoplichko VI | |||
| DeBiasi M | |||
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| P433 | issue | 6658 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | nicotine | Q12144 |
| dopamine | Q170304 | ||
| P304 | page(s) | 401-404 | |
| P577 | publication date | 1997-11-01 | |
| P1433 | published in | Nature | Q180445 |
| P1476 | title | Nicotine activates and desensitizes midbrain dopamine neurons | |
| P478 | volume | 390 |
| Q24632974 | A C. elegans model of nicotine-dependent behavior: regulation by TRP-family channels |
| Q33909918 | A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men. |
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| Q73661239 | A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study |
| Q26827751 | A neural correlate of predicted and actual reward-value information in monkey pedunculopontine tegmental and dorsal raphe nucleus during saccade tasks |
| Q30476656 | A neurocomputational hypothesis for nicotine addiction |
| Q36862752 | A possible mechanism underlying the effectiveness of acupuncture in the treatment of drug addiction |
| Q37962995 | A review of neurobiological vulnerability factors and treatment implications for comorbid tobacco dependence in schizophrenia |
| Q38016946 | A systematic review of the A118G (Asn40Asp) variant of OPRM1 in relation to smoking initiation, nicotine dependence and smoking cessation |
| Q38851564 | A threshold model for opposing actions of acetylcholine on reward behavior: Molecular mechanisms and implications for treatment of substance abuse disorders. |
| Q28680729 | A unified framework for addiction: vulnerabilities in the decision process |
| Q33669969 | ASCL1 regulates the expression of the CHRNA5/A3/B4 lung cancer susceptibility locus |
| Q24548521 | Abolished cocaine reward in mice with a cocaine-insensitive dopamine transporter |
| Q28594404 | Absence of alpha7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures |
| Q36924849 | Acetylcholine release in the mesocorticolimbic dopamine system during cocaine seeking: conditioned and unconditioned contributions to reward and motivation |
| Q55033428 | Acetylcholine suppresses the spread of excitation in the visual cortex revealed by optical recording: possible differential effect depending on the source of input. |
| Q34984038 | Acid-sensitive ionic channels in midbrain dopamine neurons are sensitive to ammonium, which may contribute to hyperammonemia damage |
| Q41913001 | Acquired appetitive responding to intravenous nicotine reflects a Pavlovian conditioned association. |
| Q44026117 | Activation of ATP receptor increases the cytosolic Ca(2+) concentration in ventral tegmental area neurons of rat brain |
| Q34137278 | Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption |
| Q42522832 | Acute and long-term changes in the mesolimbic dopamine pathway after systemic or local single nicotine injections |
| Q35182062 | Acute in vivo nicotine administration enhances synchrony among dopamine neurons |
| Q59871599 | Acute psychomotor, subjective and physiological responses to smoking in depressed outpatient smokers and matched controls |
| Q41076048 | Addictive neurons |
| Q33939531 | Addictive nicotine alters local circuit inhibition during the induction of in vivo hippocampal synaptic potentiation |
| Q36319872 | Adolescent rats are resistant to adaptations in excitatory and inhibitory mechanisms that modulate mesolimbic dopamine during nicotine withdrawal |
| Q47161754 | Advances in Behavioral Laboratory Methods that Inform Tobacco Regulatory Science: A TCORS Working Group Special Issue |
| Q33801734 | Afferent modulation of dopamine neuron firing patterns |
| Q37363808 | Age dependent nicotinic influences over dopamine neuron synaptic plasticity |
| Q35174622 | Age-related changes in nicotine response of cholinergic and non-cholinergic laterodorsal tegmental neurons: implications for the heightened adolescent susceptibility to nicotine addiction |
| Q42684568 | Allosteric nicotinic receptors, human pathologies. |
| Q34717418 | Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. |
| Q48911423 | Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice. |
| Q28585195 | Altered baroreflex responses in alpha7 deficient mice |
| Q28189111 | An association study of DRD5 with smoking initiation and progression to nicotine dependence |
| Q36378201 | Anxiolytic- and antidepressant-like effects of the methadone metabolite 2-ethyl-5-methyl-3,3-diphenyl-1-pyrroline (EMDP). |
| Q35631485 | Anxiolytic-like and anxiogenic-like effects of nicotine are regulated via diverse action at β2*nicotinic acetylcholine receptors |
| Q37024967 | Association Between CHRNA3 and CHRNA5 Nicotine Receptor Subunit Gene Variants and Nicotine Dependence in an Isolated Population of Kashubians in Poland. |
| Q38725376 | Association between smoking behaviour and genetic variants of glial cell line-derived neurotrophic factor |
| Q30623193 | Association of a nicotinic receptor gene polymorphism with spontaneous eyeblink rates |
| Q37735805 | Basal ganglia control of substantia nigra dopaminergic neurons. |
| Q37381476 | Baseline impulsive choice predicts the effects of nicotine and nicotine withdrawal on impulsivity in rats. |
| Q37643422 | Behavioral and Biochemical Interaction Between Nicotine and Chronic Unpredictable Mild Stress in Mice |
| Q42154370 | Behavioural and biochemical evidence for interactions between Delta 9-tetrahydrocannabinol and nicotine. |
| Q42022968 | Biological basis of tobacco addiction: Implications for smoking-cessation treatment |
| Q35773685 | Biomarkers to optimize the treatment of nicotine dependence |
| Q35679955 | Blockade of dopamine d4 receptors attenuates reinstatement of extinguished nicotine-seeking behavior in rats |
| Q37164812 | Blocking cannabinoid CB1 receptors for the treatment of nicotine dependence: insights from pre-clinical and clinical studies |
| Q36122868 | Bupropion inhibits the cellular effects of nicotine in the ventral tegmental area |
| Q30983911 | Ca(2+) changes induced by different presynaptic nicotinic receptors in separate populations of individual striatal nerve terminals |
| Q44598090 | Ca2+-dependent inward current induced by nicotinic receptor activation depends on Ca2+/calmodulin–CaMKII pathway in dopamine neurons |
| Q46635637 | Carbachol induces burst firing of dopamine cells in the ventral tegmental area by promoting calcium entry through L-type channels in the rat. |
| Q34498016 | Cellular mechanisms of nicotine addiction |
| Q33210260 | Central nicotinic stimulation reduces vascular conductance in the gingiva in anesthetized rats |
| Q35182023 | Characterizing functional α6β2 nicotinic acetylcholine receptors in vitro: mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells |
| Q37259110 | Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in rats |
| Q33691659 | Cholinergic axon terminals in the ventral tegmental area target a subpopulation of neurons expressing low levels of the dopamine transporter |
| Q43732560 | Cholinergic modulation of stellate cells in the mammalian ventral cochlear nucleus. |
| Q36248758 | Chrna5 genotype determines the long-lasting effects of developmental in vivo nicotine exposure on prefrontal attention circuitry |
| Q40821290 | Chronic exposure to nicotine upregulates the human (alpha)4((beta)2 nicotinic acetylcholine receptor function. |
| Q28566647 | Chronic nicotine modifies skeletal muscle Na,K-ATPase activity through its interaction with the nicotinic acetylcholine receptor and phospholemman |
| Q37454529 | Chronic nicotine selectively enhances alpha4beta2* nicotinic acetylcholine receptors in the nigrostriatal dopamine pathway. |
| Q36335508 | Chronic sazetidine-A at behaviorally active doses does not increase nicotinic cholinergic receptors in rodent brain. |
| Q37722609 | Chronic sazetidine-A maintains anxiolytic effects and slower weight gain following chronic nicotine without maintaining increased density of nicotinic receptors in rodent brain |
| Q33713902 | Cigarette smoking. |
| Q34132700 | Cocaine inhibition of nicotinic acetylcholine receptors influences dopamine release |
| Q28071876 | Cognitive Dysfunction, Affective States, and Vulnerability to Nicotine Addiction: A Multifactorial Perspective |
| Q48405808 | Common aspects of the action of nicotine and other drugs of abuse |
| Q37386620 | Communication networks in the brain: neurons, receptors, neurotransmitters, and alcohol |
| Q36293008 | Complex interactions between nicotine and nonpharmacological stimuli reveal multiple roles for nicotine in reinforcement. |
| Q28472422 | Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference |
| Q24634619 | Control of sleep and wakefulness |
| Q36623381 | Current and emerging treatment approaches for tobacco dependence |
| Q28364647 | Depression and substance use in minority middle-school students |
| Q46691940 | Desensitization of catecholamine release. The novel catecholamine release-inhibitory peptide catestatin (chromogranin a344-364) acts at the receptor to prevent nicotinic cholinergic tolerance |
| Q30455063 | Developmental effects of acute, chronic, and withdrawal from chronic nicotine on fear conditioning. |
| Q36063653 | Developmental regulation of nicotinic acetylcholine receptors within midbrain dopamine neurons |
| Q41145672 | Differential Effects of Toluene and Ethanol on Dopaminergic Neurons of the Ventral Tegmental Area. |
| Q44418971 | Differential desensitization and distribution of nicotinic acetylcholine receptor subtypes in midbrain dopamine areas. |
| Q46945509 | Differential modulation by nicotine of substantia nigra versus ventral tegmental area dopamine neurons |
| Q46220422 | Distinctive nicotinic acetylcholine receptor functional phenotypes of rat ventral tegmental area dopaminergic neurons |
| Q28586513 | Distribution and pharmacology of alpha 6-containing nicotinic acetylcholine receptors analyzed with mutant mice |
| Q48190599 | Distributions of nicotinic acetylcholine receptor alpha7 and beta2 subunits on cultured hippocampal neurons |
| Q28067590 | Diversity of Dopaminergic Neural Circuits in Response to Drug Exposure |
| Q43263076 | Donepezil modulates nicotinic receptors of substantia nigra dopaminergic neurones |
| Q30871000 | Dopamine D1 and D2 receptor mRNA up-regulation in the caudate-putamen and nucleus accumbens of rat brains by smoking |
| Q45161642 | Dopamine D3 receptor ligands block nicotine-induced conditioned place preferences through a mechanism that does not involve discriminative-stimulus or antidepressant-like effects |
| Q92423465 | Dopamine D4 Receptor Gene Exon III VNTR Variant Influences Smoking Status in Turkish Population |
| Q33751420 | Dopamine D₂ and acetylcholine α7 nicotinic receptors have subcellular distributions favoring mediation of convergent signaling in the mouse ventral tegmental area |
| Q44171253 | Dopamine agonist and antagonist responders as related to types of nicotine craving and facets of extraversion |
| Q34068906 | Dopamine function in cigarette smokers: an [¹⁸F]-DOPA PET study |
| Q35941665 | Dopamine mechanisms and cocaine reward |
| Q24681363 | Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. |
| Q37344627 | Dopamine signaling differences in the nucleus accumbens and dorsal striatum exploited by nicotine |
| Q52146893 | Dopamine-dependent modulation of rat globus pallidus excitation by nicotine acetylcholine receptors. |
| Q28084459 | Dopaminergic and cholinergic learning mechanisms in nicotine addiction |
| Q34273699 | Drug dependence as a disorder of neural plasticity: focus on dopamine and glutamate |
| Q27307876 | Drug-dependent behaviors and nicotinic acetylcholine receptor expressions in Caenorhabditis elegans following chronic nicotine exposure. |
| Q34013689 | Drugs of abuse and stress impair LTP at inhibitory synapses in the ventral tegmental area. |
| Q23921511 | Effect of in vivo nicotine exposure on chlorpyrifos pharmacokinetics and pharmacodynamics in rats |
| Q48307117 | Effect of ventral tegmental 6-hydroxydopamine lesions on the locomotor stimulant action of nicotine in rats |
| Q37576339 | Effectiveness of nicotinic agonists as desensitizers at presynaptic α4β2- and α4α5β2-nicotinic acetylcholine receptors |
| Q44539113 | Effects of acute and chronic nicotine on somatodendritic dopamine release of the rat ventral tegmental area: in vivo microdialysis study |
| Q37185374 | Effects of baclofen on conditioned rewarding and discriminative stimulus effects of nicotine in rats |
| Q35044348 | Effects of benzothiazepines on human neuronal nicotinic receptors expressed in Xenopus oocytes |
| Q30471073 | Effects of drugs of abuse on putative rostromedial tegmental neurons, inhibitory afferents to midbrain dopamine cells |
| Q42440283 | Effects of nicotine in the dopaminergic system of mice lacking the alpha4 subunit of neuronal nicotinic acetylcholine receptors. |
| Q44551686 | Effects of nicotine on memory impairment induced by blockade of muscarinic, nicotinic and dopamine D2 receptors in rats |
| Q38381191 | Effects of nicotine on novelty detection and memory recognition performance: double-blind, placebo-controlled studies of smokers and nonsmokers. |
| Q48400218 | Effects of repeated nicotine pre-treatment on mesoprefrontal dopaminergic and behavioral responses to acute footshock stress |
| Q92295728 | Effects of the peer metagenomic environment on smoking behavior |
| Q56334117 | Electrochemical Measurements of Acetylcholine-Stimulated Dopamine Release in Adult Drosophila melanogaster Brains |
| Q34961709 | Endogenous cholinergic inputs and local circuit mechanisms govern the phasic mesolimbic dopamine response to nicotine. |
| Q28650541 | Endogenous cholinergic neurotransmission contributes to behavioral sensitization to morphine |
| Q35202878 | Endogenous fatty acid ethanolamides suppress nicotine-induced activation of mesolimbic dopamine neurons through nuclear receptors |
| Q43857748 | Enhanced motor activity and brain dopamine turnover in mice during long-term nicotine administration in the drinking water |
| Q51907917 | Enhanced nicotinic receptor function and drug abuse vulnerability. |
| Q43444237 | Enhanced smoking cue salience associated with depression severity in nicotine-dependent individuals: a preliminary fMRI study |
| Q36982997 | Enhancement of cocaine-seeking behavior by repeated nicotine exposure in rats |
| Q27687624 | Ethanol action on dopaminergic neurons in the ventral tegmental area: interaction with intrinsic ion channels and neurotransmitter inputs |
| Q48243202 | Ethanol-nicotine interactions at alpha-bungarotoxin-insensitive nicotinic acetylcholine receptors in rat cortical neurons |
| Q44654064 | Evidence for the presence of nicotinic receptors on rat subfornical organ neurons |
| Q42164271 | Excitatory and inhibitory responses of dopamine neurons in the ventral tegmental area to nicotine. |
| Q36274171 | Exposure to nicotine and sensitization of nicotine-induced behaviors |
| Q42860453 | Exposure to nicotine produces an increase in dopamine D2(High) receptors: a possible mechanism for dopamine hypersensitivity |
| Q43882948 | Expression of neuronal nicotinic acetylcholine receptor subunit mRNAs within midbrain dopamine neurons |
| Q41010706 | Fenofibrate Administration Reduces Alcohol and Saccharin Intake in Rats: Possible Effects at Peripheral and Central Levels |
| Q48832474 | Frequency-Dependent Modulation of Dopamine Release by Nicotine and Dopamine D1 Receptor Ligands: An In Vitro Fast Cyclic Voltammetry Study in Rat Striatum |
| Q37602515 | From smoking to lung cancer: the CHRNA5/A3/B4 connection |
| Q44519218 | Fulfenamic acid sensitive, Ca(2+)-dependent inward current induced by nicotinic acetylcholine receptors in dopamine neurons |
| Q36967668 | Functional internal complexity of amygdala: focus on gene activity mapping after behavioral training and drugs of abuse |
| Q34847679 | Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons |
| Q45293093 | Functional polymorphisms in the human beta4 subunit of nicotinic acetylcholine receptors |
| Q35847720 | GABAergic actions mediate opposite ethanol effects on dopaminergic neurons in the anterior and posterior ventral tegmental area |
| Q36829619 | Genetic analysis of polymorphisms in dopamine receptor and transporter genes for association with smoking among cancer patients |
| Q47938136 | Genetic and environmental risk factors in Parkinson's disease |
| Q48510920 | Genetic dissociation of two behaviors associated with nicotine addiction: beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome. |
| Q46072198 | Genetic inhibition of neurotransmission reveals role of glutamatergic input to dopamine neurons in high-effort behavior |
| Q37264547 | Genetic variation in the dopamine pathway and smoking cessation |
| Q45919188 | Genetic variation influences on the early development of reactive emotions and their regulation by attention. |
| Q57032352 | Genome-wide association study identifies glutamate ionotropic receptor GRIA4 as a risk gene for comorbid nicotine dependence and major depression |
| Q36560437 | Guidelines on nicotine dose selection for in vivo research. |
| Q46679042 | Harmane inhibits serotonergic dorsal raphe neurons in the rat. |
| Q35353532 | Historical and current perspective on tobacco use and nicotine addiction |
| Q43712688 | History of tobacco and health |
| Q42615631 | How Intravenous Nicotine Administration in Smokers Can Inform Tobacco Regulatory Science |
| Q24631269 | How addictive drugs disrupt presynaptic dopamine neurotransmission |
| Q33815480 | Hypothesis for temporal displacement of metabolic and neuronal accommodation in smoking addiction |
| Q34086981 | Immotile sperm and infertility in mice lacking mitochondrial voltage-dependent anion channel type 3. |
| Q36451065 | Impact of prefrontal cortex in nicotine-induced excitation of ventral tegmental area dopamine neurons in anesthetized rats |
| Q37603263 | Impacts of chronic low-level nicotine exposure on Caenorhabditis elegans reproduction: identification of novel gene targets |
| Q41290146 | Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele |
| Q44869606 | Individual variability of dopamine release from nucleus accumbens induced by nicotine |
| Q38317062 | Individual variation in the expression profiles of nicotinic receptors in the olfactory bulb and trigeminal ganglion and identification of alpha2, alpha6, alpha9, and beta3 transcripts |
| Q33504408 | Influences of polymorphic variants of DRD2 and SLC6A3 genes, and their combinations on smoking in Polish population |
| Q30448803 | Insights into the neurobiology of the nicotinic cholinergic system and nicotine addiction from mice expressing nicotinic receptors harboring gain-of-function mutations |
| Q34543525 | Intrinsic membrane properties and synaptic inputs regulating the firing activity of the dopamine neurons. |
| Q36666651 | It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood |
| Q35598427 | Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system |
| Q35659644 | Levamisole enhances the rewarding and locomotor-activating effects of cocaine in rats |
| Q36375076 | Local application of drugs to study nicotinic acetylcholine receptor function in mouse brain slices |
| Q42468426 | Local perfusion of nicotine differentially modulates somatodendritic dopamine release in the rat ventral tegmental area after nicotine preexposure |
| Q28513200 | Long-term effects of chronic nicotine exposure on brain nicotinic receptors |
| Q51381056 | Long-term potentiation of excitatory inputs to brain reward areas by nicotine. |
| Q28484969 | Low dose nicotine and antagonism of β2 subunit containing nicotinic acetylcholine receptors have similar effects on affective behavior in mice |
| Q24647069 | Mammalian nicotinic acetylcholine receptors: from structure to function |
| Q28263028 | Mecamylamine - a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders |
| Q43349394 | Mecamylamine effects on haloperidol-induced catalepsy and defecation |
| Q37018610 | Mechanism-based medication development for the treatment of nicotine dependence. |
| Q34117342 | Mechanisms involved in nicotinic acetylcholine receptor-induced neurotransmitter release from sympathetic nerve terminals in the mouse vas deferens |
| Q28588523 | Megacystis, mydriasis, and ion channel defect in mice lacking the alpha3 neuronal nicotinic acetylcholine receptor |
| Q37508580 | Modeling nicotinic neuromodulation from global functional and network levels to nAChR based mechanisms |
| Q37467418 | Modulation of ethanol drinking-in-the-dark by mecamylamine and nicotinic acetylcholine receptor agonists in C57BL/6J mice |
| Q39237094 | Modulation of ethanol reward sensitivity by nicotinic acetylcholine receptors containing the α6 subunit |
| Q73196393 | Modulatory role of presynaptic nicotinic receptors in synaptic and non-synaptic chemical communication in the central nervous system |
| Q27679259 | Molecular actions of smoking cessation drugs at 4 2 nicotinic receptors defined in crystal structures of a homologous binding protein |
| Q28564628 | Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei |
| Q37327392 | Molecular mechanisms underlying the motivational effects of nicotine |
| Q27008063 | Molecules and circuits involved in nicotine addiction: The many faces of smoking |
| Q35033013 | Monitoring rapid chemical communication in the brain. |
| Q46881166 | Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. |
| Q36949566 | Morphine dependence and withdrawal induced changes in cholinergic signaling |
| Q43814506 | Muscarine reduces calcium-dependent electrical activity in substantia nigra dopaminergic neurons |
| Q44238764 | Muscarinic and nicotinic presynaptic modulation of EPSCs in the nucleus accumbens during postnatal development |
| Q73466811 | Muscarinic receptors depress GABAergic synaptic transmission in rat midbrain dopamine neurons |
| Q36890894 | Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity. |
| Q35566709 | Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses |
| Q60046151 | Neurobiological Determinants of Tobacco Smoking in Schizophrenia |
| Q91991315 | Neurobiological and Neurophysiological Mechanisms Underlying Nicotine Seeking and Smoking Relapse |
| Q34498032 | Neurobiology of the nicotine withdrawal syndrome |
| Q38122913 | Neurocognitive endophenotypes in schizophrenia: modulation by nicotinic receptor systems |
| Q36137598 | Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions |
| Q28214998 | Neuronal nicotinic receptors: from protein structure to function |
| Q34616154 | Neuronal systems underlying behaviors related to nicotine addiction: neural circuits and molecular genetics. |
| Q36376434 | Neuropharmacology and potential efficacy of new treatments for tobacco dependence |
| Q57156824 | Neuropharmacology of attention |
| Q34637004 | Neurophysiology of Nicotine Addiction |
| Q34431904 | Neurotransmitter release mechanisms in sympathetic neurons: past, present, and future perspectives |
| Q93166221 | Nicotine Addiction: Neurobiology and Mechanism |
| Q36316802 | Nicotine Dependence Reveals Distinct Responses from Neurons and Their Resident Nicotinic Receptors in Medial Habenula |
| Q90190112 | Nicotine Gateway Effects on Adolescent Substance Use |
| Q58183149 | Nicotine Self-Administration in Animals: A Reevaluation |
| Q36298360 | Nicotine addiction and comorbidity with alcohol abuse and mental illness |
| Q36203479 | Nicotine addiction through a neurogenomic prism: ethics, public health, and smoking |
| Q34552613 | Nicotine addiction: the possible role of functional upregulation |
| Q34988469 | Nicotine alters limbic function in adolescent rat by a 5-HT1A receptor mechanism |
| Q44898077 | Nicotine amplifies reward-related dopamine signals in striatum |
| Q46529483 | Nicotine and amphetamine acutely cross-potentiate their behavioral and neurochemical responses in female Holtzman rats |
| Q37485944 | Nicotine and inflammatory neurological disorders |
| Q73109576 | Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus |
| Q24649630 | Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons |
| Q34450836 | Nicotine dependence |
| Q35056247 | Nicotine dependence in an isolated population of Kashubians from North Poland: a population survey. |
| Q34022102 | Nicotine exposure beginning in adolescence enhances the acquisition of methamphetamine self-administration, but not methamphetamine-primed reinstatement in male rats |
| Q48366302 | Nicotine modifies the activity of ventral tegmental area dopaminergic neurons and hippocampal GABAergic neurons |
| Q35903781 | Nicotine modulates alcohol-seeking and relapse by alcohol-preferring (P) rats in a time-dependent manner |
| Q35846864 | Nicotine persistently activates ventral tegmental area dopaminergic neurons via nicotinic acetylcholine receptors containing α4 and α6 subunits |
| Q35055171 | Nicotine potentiation of excitatory inputs to ventral tegmental area dopamine neurons |
| Q39061327 | Nicotine produces chronic behavioral sensitization with changes in accumbal neurotransmission and increased sensitivity to re-exposure. |
| Q24634536 | Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis |
| Q45763902 | Nicotine reinforcement is reduced by cannabinoid CB1 receptor blockade in the ventral tegmental area. |
| Q45791809 | Nicotine self-administered directly into the VTA by rats is weakly reinforcing but has strong reinforcement enhancing properties |
| Q28139928 | Nicotine, brain nicotinic receptors, and neuropsychiatric disorders |
| Q43285147 | Nicotine-conditioned place preference induced CREB phosphorylation and Fos expression in the adult rat brain |
| Q73436917 | Nicotine-evoked [3H]5-hydroxytryptamine release from rat striatal synaptosomes |
| Q44686779 | Nicotine-induced dopamine release in primates measured with [11C]raclopride PET. |
| Q38299405 | Nicotine-induced enhancement of glutamatergic and GABAergic synaptic transmission in the mouse amygdala. |
| Q37525085 | Nicotine-induced upregulation of nicotinic receptors: underlying mechanisms and relevance to nicotine addiction |
| Q34797496 | Nicotine-mediated activation of dopaminergic neurons in distinct regions of the ventral tegmental area |
| Q55261685 | Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission. |
| Q33894536 | Nicotinic acetylcholine receptor knockout mice as animal models for studying receptor function |
| Q37485939 | Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system |
| Q37041678 | Nicotinic acetylcholine receptor-mediated responses in medial vestibular and prepositus hypoglossi nuclei neurons showing distinct neurotransmitter phenotypes |
| Q34761238 | Nicotinic acetylcholine receptors as targets for antidepressants. |
| Q35850223 | Nicotinic acetylcholine receptors containing the α4 subunit modulate alcohol reward |
| Q37346923 | Nicotinic acetylcholine receptors containing the α6 subunit contribute to ethanol activation of ventral tegmental area dopaminergic neurons |
| Q37387682 | Nicotinic activation of laterodorsal tegmental neurons: implications for addiction to nicotine |
| Q48618313 | Nicotinic cholinergic and dopaminergic receptor mRNA expression in male and female rats with high or low preference for nicotine. |
| Q35541262 | Nicotinic cholinergic synaptic mechanisms in the ventral tegmental area contribute to nicotine addiction |
| Q46086371 | Nicotinic control of axon excitability regulates thalamocortical transmission |
| Q30993631 | Nicotinic modulation of neuronal networks: from receptors to cognition |
| Q37533310 | Nicotinic modulation of synaptic transmission and plasticity in cortico-limbic circuits |
| Q30454600 | Nicotinic neuromodulation in auditory cortex requires MAPK activation in thalamocortical and intracortical circuits |
| Q51424143 | Nicotinic receptor activation in human cerebral cortical interneurons: a mechanism for inhibition and disinhibition of neuronal networks. |
| Q48157056 | Nicotinic receptor subunit mRNA expression in dopaminergic neurons of the rat brain |
| Q36094573 | Nicotinic receptor-mediated biphasic effect on neuronal excitability in chick lateral spiriform neurons |
| Q37404292 | Nicotinic receptors and stages of nicotine dependence. |
| Q42091700 | Nicotinic receptors differentially modulate the induction and expression of behavioral sensitization to methylphenidate in rats |
| Q34156143 | Nicotinic receptors in human brain: topography and pathology |
| Q33763401 | Nicotinic receptors in the brain: correlating physiology with function |
| Q51406614 | Nicotinic receptors modulating somatodendritic and terminal dopamine release differ pharmacologically. |
| Q37129328 | Nonsynaptic chemical transmission through nicotinic acetylcholine receptors |
| Q36470847 | Novel peptide isomer strategy for stable inhibition of catecholamine release: application to hypertension |
| Q96953338 | One Is Not Enough: Understanding and Modeling Polysubstance Use |
| Q32076973 | Overview of nicotinic receptors and their roles in the central nervous system |
| Q41818202 | Partial agonists for α4β2 nicotinic receptors stimulate dopaminergic neuron firing with relatively enhanced maximal effects |
| Q37304747 | Peroxisome proliferator-activated receptor (PPAR) agonists as promising new medications for drug addiction: preclinical evidence |
| Q34009316 | Peroxisome proliferator-activated receptors-alpha modulate dopamine cell activity through nicotinic receptors |
| Q48585513 | Persistent dysfunctional frontal lobe activation in former smokers. |
| Q34104228 | Pharmacology and behavioral pharmacology of the mesocortical dopamine system |
| Q36996801 | Pharmacotherapy for tobacco cessation: nicotine agonists, antagonists, and partial agonists |
| Q34605939 | Phasic dopamine release evoked by abused substances requires cannabinoid receptor activation. |
| Q33880993 | Phasic dopamine release in appetitive behaviors and drug addiction |
| Q44223728 | Pineal melatonin and brain transmitter monoamines in CBA mice during chronic oral nicotine administration |
| Q102059037 | Polysubstance use in the U.S. opioid crisis |
| Q47403345 | Pontomesencephalic Tegmental Afferents to VTA Non-dopamine Neurons Are Necessary for Appetitive Pavlovian Learning |
| Q46111417 | Pooled analysis of three randomized, double-blind, placebo controlled trials with rimonabant for smoking cessation |
| Q36039402 | Positive and negative effects of alcohol and nicotine and their interactions: a mechanistic review. |
| Q34359231 | Potential substrates for nicotine and alcohol interactions: a focus on the mesocorticolimbic dopamine system |
| Q45188899 | Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area. |
| Q27021772 | Preclinical evidence that activation of mesolimbic alpha 6 subunit containing nicotinic acetylcholine receptors supports nicotine addiction phenotype |
| Q48130557 | Presence of functional neuronal nicotinic acetylcholine receptors in brainstem motoneurons of the rat. |
| Q37014100 | Presynaptic nicotinic receptors: a dynamic and diverse cholinergic filter of striatal dopamine neurotransmission |
| Q34749911 | Presynaptic opioid and nicotinic receptor modulation of dopamine overflow in the nucleus accumbens. |
| Q44118370 | Prior cigarette smoking initiation predicting current alcohol use: evidence for a gateway drug effect among California adolescents from eleven ethnic groups |
| Q46135988 | Properties of distinct ventral tegmental area synapses activated via pedunculopontine or ventral tegmental area stimulation in vitro. |
| Q24675948 | Properties of neuronal nicotinic acetylcholine receptor mutants from humans suffering from autosomal dominant nocturnal frontal lobe epilepsy |
| Q45272359 | Reduced nicotine reward in obesity: cross-comparison in human and mouse |
| Q36484647 | Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo |
| Q36906265 | Regulation of synaptic transmission and plasticity by neuronal nicotinic acetylcholine receptors |
| Q36243655 | Reinstatement of methamphetamine conditioned place preference in nicotine-sensitized rats |
| Q42650652 | Repeated nicotine treatment in rats with high versus low rearing activity: analyses of behavioural sensitisation and place preference |
| Q58700126 | Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA |
| Q36323545 | Reward sensitization: effects of repeated nicotine exposure and withdrawal in mice. |
| Q34173418 | Reward, addiction, withdrawal to nicotine |
| Q28214622 | Rewarding effects of the cholinergic agents carbachol and neostigmine in the posterior ventral tegmental area |
| Q36930336 | Risk factors for tobacco dependence in adolescent smokers. |
| Q30551483 | Role of CB2 cannabinoid receptors in the rewarding, reinforcing, and physical effects of nicotine |
| Q34002770 | Role of alpha7 nicotinic receptors in nicotine dependence and implications for psychiatric illness |
| Q33894548 | Role of dopamine in the behavioural actions of nicotine related to addiction |
| Q35216481 | Role of the endogenous cannabinoid system in nicotine addiction: novel insights |
| Q37242594 | Role of the glutamatergic system in nicotine dependence : implications for the discovery and development of new pharmacological smoking cessation therapies |
| Q40258113 | Roles of nicotinic acetylcholine receptor beta subunits in function of human alpha4-containing nicotinic receptors |
| Q33939461 | Route of nicotine administration influences in vivo dopamine neuron activity: habituation, needle injection, and cannula infusion |
| Q37314383 | Selective inhibition of acetylcholine-evoked responses of alpha7 neuronal nicotinic acetylcholine receptors by novel tris- and tetrakis-azaaromatic quaternary ammonium antagonists |
| Q34310032 | Selective stimulation of serotonin2c receptors blocks the enhancement of striatal and accumbal dopamine release induced by nicotine administration |
| Q46679009 | Severity of nicotine dependence modulates cue-induced brain activity in regions involved in motor preparation and imagery |
| Q88561566 | Stoichiometry of the Heteromeric Nicotinic Receptors of the Renshaw Cell |
| Q43061652 | Strategies for smoking cessation: what is new and what works? |
| Q51419536 | Striatal application of nicotine, but not of lobeline, attenuates dopamine release in freely moving rats. |
| Q30487079 | Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice. |
| Q28506626 | Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice |
| Q43925474 | Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas |
| Q34087642 | Synaptic plasticity and nicotine addiction |
| Q38756961 | TC-2559 excites dopaminergic neurones in the ventral tegmental area by stimulating alpha4beta2-like nicotinic acetylcholine receptors in anaesthetised rats. |
| Q34953245 | Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence |
| Q37189885 | The CHRNA3 rs578776 Variant is Associated with an Intrinsic Reward Sensitivity Deficit in Smokers |
| Q33793233 | The alpha7 nicotinic acetylcholine receptor in neuronal plasticity |
| Q64056779 | The concept of exposure when selecting comparison groups for determining individual susceptibility to addiction to cigarette smoking |
| Q38344063 | The dissection of transcriptional modules regulated by various drugs of abuse in the mouse striatum |
| Q36083476 | The dopamine hypothesis of drug addiction: hypodopaminergic state. |
| Q35111634 | The dopamine-containing neuron: maestro or simple musician in the orchestra of addiction? |
| Q41584797 | The effect of epibatidine on spontaneous and evoked neurotransmitter release in the mouse and guinea pig isolated vas deferens. |
| Q31878432 | The effect of nicotine and haloperidol co-treatment on nicotinic receptor levels in the rat brain |
| Q46605171 | The effects of chronic nicotine on spatial learning and bromodeoxyuridine incorporation into the dentate gyrus of the rat. |
| Q33933562 | The effects of nicotine on neural pathways implicated in depression: a factor in nicotine addiction? |
| Q37291517 | The endocannabinoid system: a new molecular target for the treatment of tobacco addiction. |
| Q42629750 | The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague-Dawley rats of different ages |
| Q42259547 | The influence of lobeline on nucleus accumbens dopamine and locomotor responses to nicotine in nicotine-pretreated rats |
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| Q35621339 | The neurobiology of nicotine addiction: bridging the gap from molecules to behaviour |
| Q34419501 | The nicotinic acetylcholine receptor alpha5 subunit plays a key role in attention circuitry and accuracy. |
| Q35598392 | The nicotinic acetylcholine receptor subtypes and their function in the hippocampus and cerebral cortex |
| Q44519057 | The nicotinic alpha 4 beta 2 receptor selective agonist, TC-2559, increases dopamine neuronal activity in the ventral tegmental area of rat midbrain slices |
| Q51363792 | The nicotinic antagonist mecamylamine preferentially inhibits cocaine vs. food self-administration in rats. |
| Q62965129 | The nicotinic modulation of [3H]D-aspartate outflow in primary cultures of rat neocortical neurons: effect of acute and long term nicotine treatment |
| Q35111446 | The potential role of cotinine in the cognitive and neuroprotective actions of nicotine |
| Q34002757 | The putative role of extra-synaptic mesolimbic dopamine in the neurobiology of nicotine dependence |
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| Q30491487 | The role of NMDA receptor antagonists in nicotine tolerance, sensitization, and physical dependence: a preclinical review |
| Q48157802 | The role of beta 2-subunit-containing nicotinic acetylcholine receptors in the brain explored with a mutant mouse |
| Q38338790 | The role of mesoaccumbens dopamine in nicotine dependence |
| Q28576908 | The serotonin 2C receptor agonist Ro-60-0175 attenuates effects of nicotine in the five-choice serial reaction time task and in drug discrimination |
| Q36181346 | The therapeutic potential of nicotine and nicotinic agonists for weight control |
| Q34837643 | The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental area |
| Q36519493 | Tobacco addiction |
| Q47777284 | Tobacco particulate matter self-administration in rats: differential effects of tobacco type |
| Q37357762 | Toward a physical basis of attention and self regulation |
| Q41786836 | Trapping of ivermectin by a pentameric ligand-gated ion channel upon open-to-closed isomerization |
| Q30739506 | Ultrastructural localization of the alpha4-subunit of the neuronal acetylcholine nicotinic receptor in the rat substantia nigra. |
| Q73689123 | Variations in desensitization of nicotinic acetylcholine receptors from hippocampus and midbrain dopamine areas |
| Q43612496 | Who am I? The role of self-conflict in adolescents' responses to cigarette advertising |
| Q45078539 | Why do schizophrenic patients smoke? |
| Q89059740 | c-Fos marking of identified midbrain neurons coactive after nicotine administration in-vivo |
| Q36166333 | α2-Null mutant mice have altered levels of neuronal activity in restricted midbrain and limbic brain regions during nicotine withdrawal as demonstrated by cfos expression. |
| Q37422769 | α4α6β2* nicotinic acetylcholine receptor activation on ventral tegmental area dopamine neurons is sufficient to stimulate a depolarizing conductance and enhance surface AMPA receptor function |
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