Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption

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Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption is …
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scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.2601-10.2010
P932PMC publication ID2941435
P698PubMed publication ID20668200

P2093author name stringAndrew R Tapper
Paul D Gardner
Rubing Zhao-Shea
Xueyan Pang
Linzy M Hendrickson
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Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, selectively decreases ethanol consumption and seekingQ30502320
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Varenicline reduces alcohol self-administration in heavy-drinking smokersQ33825408
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Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependenceQ33870433
Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trialQ33997418
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Agonism of the endocannabinoid system modulates binge-like alcohol intake in male C57BL/6J mice: involvement of the posterior ventral tegmental areaQ37387731
Modulation of ethanol drinking-in-the-dark by mecamylamine and nicotinic acetylcholine receptor agonists in C57BL/6J miceQ37467418
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Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial.Q38405712
Alcohol modulation of neuronal nicotinic acetylcholine receptors is alpha subunit dependentQ40724473
The alpha4beta2 nicotinic acetylcholine-receptor partial agonist varenicline inhibits both nicotine self-administration following repeated dosing and reinstatement of nicotine seeking in ratsQ43228295
P433issue30
P407language of work or nameEnglishQ1860
P921main subjectalcohol consumptionQ2647488
vareniclineQ411330
P304page(s)10169-10176
P577publication date2010-07-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleActivation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption
P478volume30

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