Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells.

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Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1534/GENETICS.166.4.1701
P932PMC publication ID1470833
P698PubMed publication ID15126391
P5875ResearchGate publication ID276967851

P50authorMichael A ResnickQ62124589
Kevin LewisQ114725822
P2093author name stringPatrick Sung
Francesca Storici
Stephen Van Komen
Shanna Calero
P2860cites workThe Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repairQ24303369
Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamilyQ27625340
Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPaseQ27631960
Yeast Xrs2 Binds DNA and Helps Target Rad50 and Mre11 to DNA EndsQ27930530
Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombinationQ27930776
A requirement for recombinational repair in Saccharomyces cerevisiae is caused by DNA replication defects of mec1 mutantsQ27935496
Complex formation and functional versatility of Mre11 of budding yeast in recombinationQ27935743
The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorderQ28115238
Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiaeQ28140402
Alterations of the double-strand break repair gene MRE11 in cancerQ28200326
Human Rad50/Mre11 is a flexible complex that can tether DNA endsQ28210390
Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complexQ28215094
The yeast Xrs2 complex functions in S phase checkpoint regulationQ28349491
Fidelity of mitotic double-strand-break repair in Saccharomyces cerevisiae: a role for SAE2/COM1Q28769047
Role of RAD52 epistasis group genes in homologous recombination and double-strand break repairQ29618204
The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage responseQ33594907
Human MRE11 is inactivated in mismatch repair-deficient cancersQ33757629
Alteration of gene conversion tract length and associated crossing over during plasmid gap repair in nuclease-deficient strains of Saccharomyces cerevisiaeQ33855288
The 3'-->5' exonucleases of DNA polymerases delta and epsilon and the 5'-->3' exonuclease Exo1 have major roles in postreplication mutation avoidance in Saccharomyces cerevisiaeQ33957467
The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiaeQ33960277
Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiaeQ33984271
Recombination factors of Saccharomyces cerevisiaeQ33984330
Requirement for end-joining and checkpoint functions, but not RAD52-mediated recombination, after EcoRI endonuclease cleavage of Saccharomyces cerevisiae DNAQ33994195
Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiaeQ34048739
Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexesQ34104835
A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damageQ34430366
Alteration of N-terminal phosphoesterase signature motifs inactivates Saccharomyces cerevisiae Mre11.Q34605521
The Saccharomyces cerevisiae mre11(ts) allele confers a separation of DNA repair and telomere maintenance functionsQ34609697
Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolismQ34613942
Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase).Q34614221
The Mre11 complex: at the crossroads of dna repair and checkpoint signallingQ34623788
Recombination during transformation as a source of chimeric mammalian artificial chromosomes in yeast (YACs)Q36724541
Formation of the yeast Mre11-Rad50-Xrs2 complex is correlated with DNA repair and telomere maintenanceQ38325399
Integrity of human YACs during propagation in recombination-deficient yeast strainsQ38326896
Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutantsQ41688249
The repair of double-strand breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic controlQ43572485
Complementation between N-terminal Saccharomyces cerevisiae mre11 alleles in DNA repair and telomere length maintenanceQ44267659
Genes required for ionizing radiation resistance in yeastQ53676891
Exonuclease activity is required for sequence addition and Cdc13p loading at a de novo telomereQ64388053
A DNA damage response pathway controlled by Tel1 and the Mre11 complexQ64388109
Control of crossing overQ64388320
The role of the Mre11-Rad50-Xrs2 complex in telomerase- mediated lengthening of Saccharomyces cerevisiae telomeresQ74503540
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectSaccharomyces cerevisiaeQ719725
P1104number of pages13
P304page(s)1701-1713
P577publication date2004-04-01
P1433published inGeneticsQ3100575
P1476titleRole of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand breaks in mitotic cells
P478volume166