Inhibition of the NF-kappaB pathway by varicella-zoster virus in vitro and in human epidermal cells in vivo.

scientific article

Inhibition of the NF-kappaB pathway by varicella-zoster virus in vitro and in human epidermal cells in vivo. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.01956-05
P932PMC publication ID1472140
P698PubMed publication ID16698992

P50authorAnn ArvinQ4766238
Jeremy O JonesQ78720330
P2860cites workA cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaBQ24321775
The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinaseQ24561643
The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genesQ24607496
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The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitinationQ28201717
Oscillations in NF-kappaB signaling control the dynamics of gene expressionQ28289121
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathwayQ28615591
The IkappaB-NF-kappaB signaling module: temporal control and selective gene activationQ29617813
Microarray analysis of host cell gene transcription in response to varicella-zoster virus infection of human T cells and fibroblasts in vitro and SCIDhu skin xenografts in vivoQ30531746
Herpes simplex virus ICP0 mutants are hypersensitive to interferonQ33798242
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.Q34131747
Varicella-zoster virus (VZV) ORF17 protein induces RNA cleavage and is critical for replication of VZV at 37 degrees C but not 33 degrees C.Q34349183
mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nucleaseQ34362360
Mutational analysis of the varicella-zoster virus ORF62/63 intergenic regionQ34434911
Activation and inhibition of virus and interferon: the herpesvirus storyQ34600005
Epstein-Barr virus latent membrane protein 1 activation of NF-kappaB through IRAK1 and TRAF6.Q34789652
Nf-kappa B, chemokine gene transcription and tumour growthQ34810265
Ubiquitin: not just for proteasomes anymoreQ35089381
Activation of alternative NF-kappa B pathway by human herpes virus 8-encoded Fas-associated death domain-like IL-1 beta-converting enzyme inhibitory protein (vFLIP).Q35319917
Regulation of JAK-STAT signalling in the immune systemQ35605437
Functions of NF-kappaB1 and NF-kappaB2 in immune cell biologyQ35815962
Tropism of varicella-zoster virus for human CD4+ and CD8+ T lymphocytes and epidermal cells in SCID-hu miceQ35845405
Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promotersQ35845633
The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-Q35964369
Multiple mechanisms are implicated in the regulation of NF-kappa B activity during human cytomegalovirus infectionQ36090467
Activation of NF-kappaB in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosisQ36350435
Varicella-zoster virus transfer to skin by T Cells and modulation of viral replication by epidermal cell interferon-alphaQ36403830
Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.Q36803871
A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.Q37421291
Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virusQ37583533
Efficient replication by herpes simplex virus type 1 involves activation of the IkappaB kinase-IkappaB-p65 pathwayQ37683123
Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferonQ39593618
Herpes simplex virus ICP0 and ICP34.5 counteract distinct interferon-induced barriers to virus replicationQ39682468
Promoter sequences of varicella-zoster virus glycoprotein I targeted by cellular transactivating factors Sp1 and USF determine virulence in skin and T cells in SCIDhu mice in vivoQ39698466
Glycoprotein I of varicella-zoster virus is required for viral replication in skin and T cellsQ39753125
An IkappaB homolog encoded by African swine fever virus provides a novel mechanism for downregulation of proinflammatory cytokine responses in host macrophagesQ39877213
Activities of heterodimers composed of DNA-binding- and transactivation-deficient subunits of the herpes simplex virus regulatory protein ICP4Q40062603
Human cytomegalovirus stimulates cellular IKK2 activity and requires the enzyme for productive replication.Q40584504
Latent membrane protein 1 of Epstein-Barr virus stimulates processing of NF-kappa B2 p100 to p52.Q40628193
The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the Ikappa B kinase complexQ40752466
Cowpox virus and other members of the orthopoxvirus genus interfere with the regulation of NF-kappaB activationQ40781958
The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B.Q40816820
Herpes simplex virus type 2 induces secretion of IL-12 by macrophages through a mechanism involving NF-kappaB.Q40841212
Biological and biochemical inhibitors of the NF-kappa B/Rel proteins and cytokine synthesisQ40931087
NF-kappaB activation is responsible for the synergistic effect of herpes simplex virus type 2 infection on interferon-gamma-induced nitric oxide production in macrophagesQ40994333
Epstein-Barr virus latent membrane protein 1 activates nuclear factor-kappa B in human endothelial cells and inhibits apoptosisQ42464747
Activation of I kappa b kinase by herpes simplex virus type 1. A novel target for anti-herpetic therapyQ43626729
KSHV vFLIP binds to IKK-gamma to activate IKK.Q44532483
Induction of RANTES/CCL5 by herpes simplex virus is regulated by nuclear factor kappa B and interferon regulatory factor 3.Q44548916
Inhibition of nuclear factor kappaB activation by a virus-encoded IkappaB-like proteinQ44642218
Viral and cellular gene transcription in fibroblasts infected with small plaque mutants of varicella-zoster virus.Q45424582
Protection by herpes simplex virus glycoprotein D against Fas-mediated apoptosis: role of nuclear factor kappaB.Q45722712
Failure of measles virus to activate nuclear factor-kappa B in neuronal cells: implications on the immune response to viral infections in the central nervous system.Q45750061
Herpes simplex type 1 induction of persistent NF-kappa B nuclear translocation increases the efficiency of virus replicationQ45754258
Activation of the ppp(A2'p)nA system in interferon-treated, herpes simplex virus-infected cells and evidence for novel inhibitors of the ppp(A2'p)nA-dependent RNaseQ45807691
Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitinationQ50119689
Expression of TNF-alpha by herpes simplex virus-infected macrophages is regulated by a dual mechanism: transcriptional regulation by NF-kappa B and activating transcription factor 2/Jun and translational regulation through the AU-rich region of theQ74321530
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
P304page(s)5113-5124
P577publication date2006-06-01
P1433published inJournal of VirologyQ1251128
P1476titleInhibition of the NF-kappaB pathway by varicella-zoster virus in vitro and in human epidermal cells in vivo
P478volume80

Reverse relations

cites work (P2860)
Q33743977Cellular transcriptome analysis reveals differential expression of pro- and antiapoptosis genes by varicella-zoster virus-infected neurons and fibroblasts
Q36591683Classical swine fever virus failed to activate nuclear factor-kappa b signaling pathway both in vitro and in vivo
Q34013598Disruption of PML nuclear bodies is mediated by ORF61 SUMO-interacting motifs and required for varicella-zoster virus pathogenesis in skin
Q40709587Equine herpesvirus-1 infection disrupts interferon regulatory factor-3 (IRF-3) signaling pathways in equine endothelial cells
Q38843666Equine herpesvirus-1 suppresses type-I interferon induction in equine endothelial cells.
Q34581696Gene expression patterns in blood leukocytes discriminate patients with acute infections
Q41126737Hepatitis B reactivation in multiple myeloma patients with resolved hepatitis B undergoing chemotherapy
Q33900418Herpes simplex virus 1 protein kinase US3 hyperphosphorylates p65/RelA and dampens NF-κB activation.
Q42265673High frequency of varicella zoster virus reactivation associated with the use of arsenic trioxide in patients with acute promyelocytic leukemia
Q45411485Human immunodeficiency virus (HIV) type 1 Vpr induces differential regulation of T cell costimulatory molecules: direct effect of Vpr on T cell activation and immune function
Q92657652Interferon Gamma Inhibits Varicella-Zoster Virus Replication in a Cell Line-Dependent Manner
Q89621258Manipulation of the Innate Immune Response by Varicella Zoster Virus
Q28709497Modulation of NF-κB signalling by microbial pathogens
Q40786326Modulation of host CD59 expression by varicella-zoster virus in human xenografts in vivo
Q33791387Molecular mechanisms of varicella zoster virus pathogenesis
Q80163901Post varicella hepatic actinomycosis in a 5-year-old girl mimicking acute abdomen
Q92447215Pseudorabies Virus UL24 Abrogates Tumor Necrosis Factor Alpha-Induced NF-κB Activation by Degrading P65
Q37534033RNA-seq analysis of host and viral gene expression highlights interaction between varicella zoster virus and keratinocyte differentiation.
Q35673818Signal transducer and activator of transcription 3 (STAT3) and survivin induction by varicella-zoster virus promote replication and skin pathogenesis
Q35913878The ORF61 Protein Encoded by Simian Varicella Virus and Varicella-Zoster Virus Inhibits NF-κB Signaling by Interfering with IκBα Degradation
Q40038007The phosphorylation profile of protein kinase A substrates is modulated during Varicella-zoster virus infection
Q33828713The varicella-zoster virus ORF47 kinase interferes with host innate immune response by inhibiting the activation of IRF3
Q37606051Varicella zoster virus immune evasion strategies.
Q33828495Varicella-zoster virus T cell tropism and the pathogenesis of skin infection
Q34120083Varicella-zoster virus immediate-early protein 62 blocks interferon regulatory factor 3 (IRF3) phosphorylation at key serine residues: a novel mechanism of IRF3 inhibition among herpesviruses
Q40073483Varicella-zoster virus infection induces the secretion of interleukin-8.
Q35665805Varicella-zoster virus inhibition of the NF-κB pathway during infection of human dendritic cells: role for open reading frame 61 as a modulator of NF-κB activity
Q36315805Varicella-zoster virus modulates NF-kappaB recruitment on selected cellular promoters

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