scholarly article | Q13442814 |
P2093 | author name string | B. Hille | |
W. Schwarz | |||
P. T. Palade | |||
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Electrical activity and intracellular sodium concentration in frog muscle | Q73261004 | ||
Potassium chloride movement and the membrane potential of frog muscle | Q79130064 | ||
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The pH-dependent rate of action of local anesthetics on the node of Ranvier | Q34559874 | ||
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The site of action and active form of local anesthetics. II. Experiments with quaternary compounds | Q34703281 | ||
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Kinetic and pharmacological properties of the sodium channel of frog skeletal muscle | Q36407628 | ||
An improved vaseline gap voltage clamp for skeletal muscle fibers | Q36407642 | ||
Direct measurement of the intracellular pH of mammalian cardiac muscle | Q39132313 | ||
Saxitoxin and procaine act independently on separate sites of the sodium channel | Q39585641 | ||
Mechanism of frequency-dependent inhibition of sodium currents in frog myelinated nerve by the lidocaine derivative GEA | Q41066031 | ||
The Inhibition of Sodium Currents in Myelinated Nerve by Quaternary Derivatives of Lidocaine | Q41920650 | ||
The effects of pH on penetration and action of procaine 14C, atropine 3H, n-butanol 14C and halothane 14C in single giant axons of the squid | Q42234162 | ||
The binding of labelled saxitoxin to the sodium channels in nerve membranes | Q44902342 | ||
The binding of labelled tetrodotoxin to non-myelinated nerve fibres. | Q52439651 | ||
Local anesthetics: effects on permeability properties of nodal membrane in myelinated nerve fibres from xenopus. Potential clamp experiments. | Q52723905 | ||
The active form of local anesthetics. | Q52767720 | ||
Effect of procaine on electrical properties of squid axon membrane. | Q52771198 | ||
Effects of calcium ions and local anesthetics on electrical properties of Purkinje fibres. | Q52776323 | ||
Local anesthetics. I. The blocking potencies of some local anesthetics and of butyl alcohol determined on peripheral nerves. | Q52777947 | ||
Intracellular pH, H ion flux and H ion permeability coefficient in bullfrog toe muscle | Q69091222 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | sodium | Q658 |
biophysics | Q7100 | ||
Anura | Q53636 | ||
P1104 | number of pages | 26 | |
P304 | page(s) | 343-368 | |
P577 | publication date | 1977-12-01 | |
P1433 | published in | Biophysical Journal | Q2032955 |
P1476 | title | Local anesthetics. Effect of pH on use-dependent block of sodium channels in frog muscle | |
P478 | volume | 20 |
Q49486564 | A protein-conducting channel in the endoplasmic reticulum |
Q34257683 | A quantitative description of QX222 blockade of sodium channels in squid axons |
Q40124099 | Acetylcholine receptor kinetics |
Q51789203 | Action of benzocaine on sodium channels of frog nodes of Ranvier treated with chloramine-T. |
Q51424821 | Alkalinizing local anesthetic does not decrease pain during injection for dorsal penile nerve block. |
Q47250431 | Antagonism by local anesthetics of sodium channel activators in the presence of scorpion toxins: two mechanisms for competitive inhibition |
Q53943964 | Antiarrhythmic drugs and cardiac ion channels: mechanisms of action. |
Q28306235 | Aprindine blocks the sodium current in guinea-pig ventricular myocytes |
Q72394790 | Asymmetric proton block of inward rectifier K channels in skeletal muscle |
Q34778955 | Bacterial voltage-gated sodium channels (BacNa(V)s) from the soil, sea, and salt lakes enlighten molecular mechanisms of electrical signaling and pharmacology in the brain and heart |
Q41549896 | Block of sodium conductance by n-octanol in crayfish giant axons |
Q35872351 | Blockade by local anaesthetics of the single Ca(2+)-activated K+ channel in rat hippocampal neurones |
Q37082082 | Capsaicin combined with local anesthetics preferentially prolongs sensory/nociceptive block in rat sciatic nerve |
Q39679803 | Cardiac arrhythmia, sudden death, and psychoactive agents |
Q72386538 | Cat ventricular muscle treated with D600: characteristics of calcium channel block and unblock |
Q34125687 | Characterization of cocaine-induced block of cardiac sodium channels |
Q34575837 | Characterization of concentration- and use-dependent effects of quinidine from conduction delay and declining conduction velocity in canine Purkinje fibers |
Q40158538 | Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels |
Q34018832 | Charged tetracaine as an inactivation enhancer in batrachotoxin-modified Na+ channels |
Q41552906 | Chemical modification of sodium channel surface charges in frog skeletal muscle by trinitrobenzene sulphonic acid |
Q28476574 | Classification of drugs based on properties of sodium channel inhibition: a comparative automated patch-clamp study |
Q36412399 | Common molecular determinants of flecainide and lidocaine block of heart Na+ channels: evidence from experiments with neutral and quaternary flecainide analogues |
Q36015209 | Computational biology in the study of cardiac ion channels and cell electrophysiology. |
Q41953808 | Conotoxins as sensors of local pH and electrostatic potential in the outer vestibule of the sodium channel |
Q51866579 | Current concepts of the mechanism of action of local anesthetics. |
Q33907181 | Differences in steady-state inactivation between Na channel isoforms affect local anesthetic binding affinity |
Q40460868 | Different pH-sensitivity patterns of 30 sodium channel inhibitors suggest chemically different pools along the access pathway. |
Q42184420 | Direct inhibition of the actomyosin motility by local anesthetics in vitro |
Q40335968 | Direct quantification of apparent binding indices from quinidine-induced in vivo conduction delay in canine myocardium |
Q34017596 | Distinct local anesthetic affinities in Na+ channel subtypes |
Q72898354 | Effect of RP 30356 on the fast inward Na current in frog atrial fibres |
Q41053039 | Effect of a trial pharmaceutical solution on reversing sensations after using lidocain: An animal study |
Q53968833 | Effect of procainamide on transmembrane action potentials in guinea-pig papillary muscles as affected by external potassium concentration |
Q48690483 | Effects of amphipathic drugs onl-[3H]glutamate binding to synaptic membranes and the purified binding protein |
Q60690949 | Enantioselective relief of neuropathic pain by systemic mexiletine in the rat |
Q77731265 | Enhancing effects of salicylate on tonic and phasic block of Na+ channels by class 1 antiarrhythmic agents in the ventricular myocytes and the guinea pig papillary muscle |
Q42856497 | Evaluation of prilocaine for the reduction of pain associated with transmucosal anesthetic administration |
Q48335317 | Exploring the role of pH in modulating the effects of lidocaine in virtual ischemic tissue |
Q27324485 | Exploring volatile general anesthetic binding to a closed membrane-bound bacterial voltage-gated sodium channel via computation |
Q52702876 | Fast frequency-dependent block of action potential upstroke in rabbit atrium by small local anesthetics |
Q39769656 | Gating currents and charge movements in excitable membranes |
Q46555656 | High selectivity of calcium channels in single dialysed heart cells of the guinea-pig |
Q41447574 | Histochemical study of calcium on T-tubule membranes and in the sarcoplasmic reticulum, in frog twitch muscle fibres at rest and during activity |
Q28374367 | Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels |
Q67526951 | Imipramine and 2-hydroxyimipramine: comparative cardiotoxicity and pharmacokinetics in swine |
Q46390376 | Inactivation of human sodium channels and the effect of tocainide |
Q36410344 | Influence of pHo on calcium channel block by amlodipine, a charged dihydropyridine compound. Implications for location of the dihydropyridine receptor |
Q33152183 | Inherited and acquired vulnerability to ventricular arrhythmias: cardiac Na+ and K+ channels |
Q40983615 | Inhibition by local anesthetics of Ca2+ channels in rat anterior pituitary cells |
Q36409628 | Inhibition of sodium currents by local anesthetics in chloramine-T-treated squid axons. The role of channel activation |
Q46702076 | Inhibiton of $$\dot V_{\max } $$ of the action potential by propafenone and its voltage-, time- and pH-dependence in mammalian ventricular myocardium |
Q51875266 | Interaction of lidocaine and benzocaine in blocking sodium channels |
Q51864195 | Interaction of spin-labeled local anesthetics with the sodium channel of squid axon membranes. |
Q40300883 | Interactions between quaternary lidocaine, the sodium channel gates, and tetrodotoxin |
Q36409432 | Interactions of organic calcium channel antagonists with calcium channels in single frog atrial cells |
Q55687858 | Intramuscular infiltration of a local anesthetic, lidocaine, does not result in adverse behavioural side effects in rainbow trout. |
Q41908034 | Irreversible inhibition of sodium current and batrachotoxin binding by a photoaffinity-derivatized local anesthetic |
Q34126144 | Kinetic analysis of phasic inhibition of neuronal sodium currents by lidocaine and bupivacaine |
Q36433539 | Kinetics of 9-aminoacridine block of single Na channels |
Q52542989 | Kinetics of interaction of disopyramide with the cardiac sodium channel: fast dissociation from open channels at normal rest potentials. |
Q39631657 | Kinetics of local anesthetic inhibition of neuronal sodium currents. pH and hydrophobicity dependence |
Q41556598 | Lidocaine block of cardiac sodium channels |
Q51787811 | Local anaesthetic effects of benzene and structurally related molecules, including benzocaine, on the squid giant axon. |
Q34656530 | Local anesthetic block of sodium channels in normal and pronase-treated squid giant axons |
Q39340842 | Local anesthetic inhibition of a bacterial sodium channel |
Q36408497 | Local anesthetics QX 572 and benzocaine act at separate sites on the batrachotoxin-activated sodium channel |
Q37362215 | Local anesthetics as effectors of allosteric gating. Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels |
Q37023303 | Local anesthetics disrupt energetic coupling between the voltage-sensing segments of a sodium channel. |
Q42855770 | Local anesthetics: a century of progress |
Q46928441 | Mechanism of inhibition of the Na current by tocainide in guinea-pig isolated ventricular cells |
Q42269886 | Mechanism of inhibition of the sodium current by bepridil in guinea-pig isolated ventricular cells |
Q47230575 | Mechanisms of Drug Binding to Voltage-Gated Sodium Channels |
Q34534868 | Mechanisms of use-dependent block of sodium channels in excitable membranes by local anesthetics |
Q35006735 | Membrane porters of ATP-binding cassette transport systems are polyphyletic |
Q38997044 | Molecular Determinants of BK Channel Functional Diversity and Functioning |
Q41160240 | Molecular and structural basis of resting and use-dependent block of sodium current defined using disopyramide analogues |
Q47422850 | Molecular determinants of prokaryotic voltage-gated sodium channels for recognition of local anesthetics |
Q30474717 | Molecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system |
Q34535788 | Na channel activation gate modulates slow recovery from use-dependent block by local anesthetics in squid giant axons |
Q28365692 | Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state |
Q37365724 | Pharmacological targeting of long QT mutant sodium channels |
Q72418552 | Potency of 3,4-Diaminopyridine and 4-aminopyridine on mammalian neuromuscular transmission and the effect of pH changes |
Q48657941 | Procaine actions on tetrodotoxin sensitive and insensitive leech neurons |
Q51875256 | Properties of toxin-resistant sodium channels produced by chemical modification in frog skeletal muscle |
Q42665311 | Quinacrine (mepacrine) action at frog end-plate |
Q24555201 | Quinine blocks specific gap junction channel subtypes |
Q39219867 | Rates of block by procaine and benzocaine and the procaine-benzocaine interaction at the node of Ranvier |
Q24634668 | Role of voltage-gated sodium, potassium and calcium channels in the development of cocaine-associated cardiac arrhythmias |
Q37553511 | Sidedness of carbamazepine accessibility to voltage-gated sodium channels |
Q41243945 | Slow calcium and potassium currents in frog skeletal muscle: their relationship and pharmacologic properties |
Q24595359 | Sodium Channel Molecular Conformations and Antiarrhythmic Drug Affinity |
Q37605350 | Sodium channel blockers for the treatment of neuropathic pain |
Q51867596 | Sodium current depression by lidocaine and quinidine in isolated ventricular cells |
Q39805666 | Some aspects of the pharmacology of sodium channels in nerve membrane. Process of inactivation |
Q40923244 | State-Dependent Inhibition of Sodium Channels by Local Anesthetics: A 40-Year Evolution |
Q37384589 | State-dependent block of Na+ channels by articaine via the local anesthetic receptor |
Q73118055 | Stereoselective effects of mexiletine enantiomers on sodium currents and excitability characteristics of adult skeletal muscle fibers |
Q51714710 | Stereoselective interaction of tocainide and its chiral analogs with the sodium channels in human myoballs. |
Q40170517 | Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block. |
Q37860361 | Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review |
Q40732149 | Temperature experiments on nerve and muscle membranes of frogs. Indications for a phase transition |
Q42847976 | The activation gate of the sodium channel controls blockade and deblockade by disopyramide in rabbit Purkinje fibres |
Q51868436 | The blockade of Vmax of the atrioventricular action potential produced by the slow channel inhibitors verapamil and nifedipine. |
Q73898558 | The blocking mechanism of sodium currents by a new class I antiarrhythmic drug, Ro 22-9194, in isolated guinea-pig ventricular myocytes |
Q36003857 | The channel-blocking action of methonium compounds on rat submandibular ganglion cells |
Q35573700 | The channel-blocking action of methonium compounds on rat submandibular ganglion cells. 1983 |
Q51704198 | The different use dependences of tocainide and benzocaine are correlated with different effects on sodium channel inactivation |
Q51861121 | The effect of yohimbine on sodium and gating currents in frog ranvier node membrane |
Q46339296 | The impact of environment and resonance effects on the site of protonation of aminobenzoic acid derivatives. |
Q51668201 | The interaction of local anesthetics with the ryanodine receptor of the sarcoplasmic reticulum. |
Q72098669 | The interaction of potassium with the activation of anomalous rectification in frog muscle membrane |
Q41768716 | Tonic and phasic block of neuronal sodium currents by 5-hydroxyhexano-2',6'-xylide, a neutral lidocaine homologue |
Q51652331 | Ultra-deep blockade of Na+ channels by a quaternary ammonium ion: catalysis by a transition-intermediate state? |
Q53461325 | Updated Review of Fish Analgesia. |
Q34016917 | Use-dependent inhibition of Na+ currents by benzocaine homologs |
Q39218475 | Uses and Doses of Local Anesthetics in Fish, Amphibians, and Reptiles |
Q37326589 | Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity |
Q51874590 | Voltage-clamp experiments in normal and denervated mammalian skeletal muscle fibres. |
Q34254425 | n-Alkanols potentiate sodium channel inactivation in squid giant axons |
Q34126151 | pH-dependent binding of local anesthetics in single batrachotoxin-activated Na+ channels. Cocaine vs. quaternary compounds |
Q77654452 | pH-dependent block of the L-type Ca2+ channel current by diltiazem in human mesenteric arterial myocytes |