The PTPN22*C1858T functional polymorphism is associated with susceptibility to inflammatory polyarthritis but neither this nor other variants spanning the gene is associated with disease outcome

scientific article

The PTPN22*C1858T functional polymorphism is associated with susceptibility to inflammatory polyarthritis but neither this nor other variants spanning the gene is associated with disease outcome is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1136/ARD.2007.071894
P8608Fatcat IDrelease_odshmyuitnanrpunb6aoxjawlq
P932PMC publication ID3055597
P698PubMed publication ID17666450
P5875ResearchGate publication ID6173638

P50authorWendy ThomsonQ42653464
Deborah P.M. SymmonsQ54100237
Jane WorthingtonQ29998784
Anne BartonQ30348373
P2093author name stringA Silman
H Naseem
P2860cites workRefining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteinsQ44687984
Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: further support that PTPN22 is an autoimmunity geneQ46525978
Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort.Q46689842
The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritisQ46897903
Estimating the incidence of rheumatoid arthritis: Trying to hit a moving target?Q56446828
Genetic basis of rheumatoid arthritisQ56901751
The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch populationQ58234945
The HLA–DRB1 shared epitope alleles are primarily a risk factor for anti–cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritisQ58234961
STANFORD HEALTH ASSESSMENT QUESTIONNAIRE MODIFIED TO ASSESS DISABILITY IN BRITISH PATIENTS WITH RHEUMATOID ARTHRITISQ61912680
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4Q24538382
Haploview: analysis and visualization of LD and haplotype mapsQ27860955
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritisQ28267921
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variantQ28280659
Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twinsQ31460983
Time to first occurrence of erosions in inflammatory polyarthritis: results from a prospective community-based studyQ33951520
PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritisQ34114509
Radiological outcome in rheumatoid arthritis is predicted by presence of antibodies against cyclic citrullinated peptide before and at disease onset, and by IgA-RF at disease onsetQ35637041
The Norfolk Arthritis Register (NOAR).Q35669619
Radiographic evaluation of rheumatoid arthritis and related conditions by standard reference filmsQ41513883
Quantifying the exact role of HLA-DRB1 alleles in susceptibility to inflammatory polyarthritis: results from a large, population-based studyQ42599672
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)251-255
P577publication date2007-07-31
P1433published inAnnals of the Rheumatic DiseasesQ4767876
P1476titleThe PTPN22*C1858T functional polymorphism is associated with susceptibility to inflammatory polyarthritis but neither this nor other variants spanning the gene is associated with disease outcome
P478volume67

Reverse relations

cites work (P2860)
Q46840442Association of PTPN22 1858C→T polymorphism, HLA-DRB1 shared epitope and autoantibodies with rheumatoid arthritis.
Q64916954Baseline patient reported outcomes are more consistent predictors of long-term functional disability than laboratory, imaging or joint count data in patients with early inflammatory arthritis: A systematic review.
Q35001270Current progress in the pharmacological therapy of fibromyalgia
Q33923376Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort
Q33665938Multinational evidence-based recommendations on how to investigate and follow-up undifferentiated peripheral inflammatory arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists [...]
Q35053747The PTPN22 susceptibility risk variant is not associated with the rate of joint destruction in anti-citrullinated protein antibody-positive rheumatoid arthritis
Q36456814The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA.
Q34395284The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register

Search more.