Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E.

scientific article

Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/CNE.22525
P932PMC publication ID3056486
P698PubMed publication ID21192076
P5875ResearchGate publication ID49715316

P2093author name stringGudrun Rappold
Ruud Hovius
Michael D Gershon
Felix Lasitschka
Frank Autschbach
Beate Niesler
Michael Brüss
Dorothee Möller
Johannes Kapeller
P2860cites workThe 5-HT3B subunit is a major determinant of serotonin-receptor functionQ22001471
Characterization of the novel human serotonin receptor subunits 5-HT3C,5-HT3D, and 5-HT3EQ24301097
Molecular cloning of human 5-hydroxytryptamine3 receptor: heterogeneity in distribution and function among speciesQ24311170
Quantitative assessment of glial cells in the human and guinea pig enteric nervous system with an anti-Sox8/9/10 antibodyQ24317701
Two kinds of tryptamine receptorQ24551902
The 5-HT3 receptor as a therapeutic targetQ24681066
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Assembly and cell surface expression of homomeric and heteromeric 5-HT3 receptors: the role of oligomerization and chaperone proteinsQ28204916
The 5-HT3 receptor--the relationship between structure and functionQ28292652
Activation of intrinsic afferent pathways in submucosal ganglia of the guinea pig small intestineQ28377434
Detection of 5-HT3R-A, a 5-HT3 receptor subunit, in submucosal and myenteric ganglia of rat small intestine using in situ hybridizationQ49206112
Hu neuronal proteins are expressed in proliferating neurogenic cells.Q52219021
Evaluation of PGP9.5 in the diagnosis of Hirschsprung's diseaseQ67594935
Functional properties of a cloned 5-hydroxytryptamine ionotropic receptor subunit: comparison with native mouse receptorsQ71691690
Differential localization of 5-hydroxytryptamine3 and 5-hydroxytryptamine4 receptors in the human rectumQ73409904
Analysis of the responses of myenteric neurons in the small intestine to chemical stimulation of the mucosaQ73644862
In vivo effects of the 5-HT3 antagonist alosetron on basal and cholera toxin-induced secretion in the human jejunum: a segmental perfusion studyQ74777280
Quantification of subclasses of human colonic myenteric neurons by immunoreactivity to Hu, choline acetyltransferase and nitric oxide synthaseQ79629300
Enteric descending and afferent neural signaling stimulated by giant migrating contractions: essential contributing factors to visceral painQ80312396
Calcitonin receptor-like receptor (CLR), receptor activity-modifying protein 1 (RAMP1), and calcitonin gene-related peptide (CGRP) immunoreactivity in the rat trigeminovascular system: differences between peripheral and central CGRP receptor distribQ80472991
Enteric nervous systemQ82485896
Function, expression, and characterization of the serotonin transporter in the native human intestineQ30358983
5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult miceQ30490465
Laser microdissection as a new tool to investigate site-specific gene expression in enteric ganglia of the human intestineQ33513286
Review article: the therapeutic potential of 5-HT3 receptor antagonists in the treatment of irritable bowel syndromeQ33701266
RIC-3 exclusively enhances the surface expression of human homomeric 5-hydroxytryptamine type 3A (5-HT3A) receptors despite direct interactions with 5-HT3A, -C, -D, and -E subunitsQ34094388
Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E.Q34205102
A cluster of novel serotonin receptor 3-like genes on human chromosome 3.Q34274273
Cloning and functional expression of a human 5-hydroxytryptamine type 3AS receptor subunit.Q34401088
The medical benefit of 5-HT researchQ34558808
The serotonin signaling system: from basic understanding to drug development for functional GI disordersQ34604868
Review article: serotonin receptors and transporters -- roles in normal and abnormal gastrointestinal motilityQ34650033
A placebo-controlled trial of prucalopride for severe chronic constipationQ34782256
First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndromeQ34794063
Serotonin and its implication for the management of irritable bowel syndrome.Q35140683
Nerves, reflexes, and the enteric nervous system: pathogenesis of the irritable bowel syndromeQ36083860
Serotonin 5-HT(3) receptors in the central nervous systemQ36529851
Peripheral neural serotonin receptors: identification and characterization with specific antagonists and agonistsQ37413058
Tegaserod, a 5-HT(4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipationQ39414529
5-HT(3) receptors: role in disease and target of drugsQ39858435
Characterisation of 5-HT3C, 5-HT3D and 5-HT3E receptor subunits: evolution, distribution and function.Q39916125
Energy-dependent regulation of cell structure by AMP-activated protein kinaseQ40135869
The 5-HT3 receptor channelQ40401493
Serotonin excites neurons in the human submucous plexus via 5-HT3 receptorsQ40424072
Electrophysiological studies of 5-hydroxytryptamine receptors on enteric neuronsQ41097282
Serotonergic systemsQ41690277
5-HT4 receptor activation facilitates recovery from synaptic rundown and increases transmitter release from single varicosities of myenteric neuronsQ41843114
Overexpression of neurotrophin 4 in skin enhances myelinated sensory endings but does not influence sensory neuron numberQ43207169
Giant migrating contractions during defecation in the dog colonQ43316271
The effect of the selective 5-HT(3) receptor agonist on ferret gut motilityQ43354374
Immunoreactivity of Hu proteins facilitates identification of myenteric neurones in guinea-pig small intestineQ43970912
Expression and function of 5-HT3 receptors in the enteric neurons of mice lacking the serotonin transporterQ44185473
Neurotransmitters mediating the intestinal peristaltic reflex in the mouseQ44579407
A nonneuronal 5-hydroxytryptamine receptor 3 induces chloride secretion in the rat distal colonic mucosaQ44914338
Expression of 5-HT3A receptors in cells of the immune system.Q45130873
Post inflammatory damage to the enteric nervous system in diverticular disease and its relationship to symptoms.Q46005706
Analysis of the role of 5-HT in the enteric nervous system using anti-idiotopic antibodies to 5-HT receptorsQ46412240
5-HT1A and 5-HT4 receptors mediate inhibition and facilitation of fast synaptic transmission in enteric neuronsQ46458731
Expression and function of 5-HT4 receptors in the mouse enteric nervous systemQ46613363
Actions of 5-hydroxytryptamine on myenteric neurons in guinea pig gastric antrumQ46901955
Functional characterization of serotonin receptor subtypes in human duodenal secretion.Q46918370
Desperately seeking subunits: are native 5-HT3 receptors really homomeric complexes?Q47834129
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectserotoninQ167934
P304page(s)420-432
P577publication date2011-02-01
P1433published inThe Journal of Comparative NeurologyQ3186907
P1476titleSerotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E.
P478volume519

Reverse relations

cites work (P2860)
Q364187825-HT(3) receptors
Q44804482Analysis of free ACh and 5-HT in milk from four different species and their bioactivity on 5-HT(3) and nACh receptors
Q35644213Association of genetic polymorphisms in HTR3A and HTR3E with diarrhea predominant irritable bowel syndrome
Q43243277Differential release of β-NAD(+) and ATP upon activation of enteric motor neurons in primate and murine colons
Q35834548Distribution of 5-HT3, 5-HT4, and 5-HT7 Receptors Along the Human Colon
Q38886444Excitability and Synaptic Transmission in the Enteric Nervous System: Does Diet Play a Role?
Q37575689Irritable bowel syndrome-diarrhea: characterization of genotype by exome sequencing, and phenotypes of bile acid synthesis and colonic transit
Q34366837Irritable bowel syndrome: a microbiome-gut-brain axis disorder?
Q26860280Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Genetic epidemiology and pharmacogenetics in irritable bowel syndrome
Q93551700Ligand-Gated Ion Channels
Q56971318Natural compounds boldine and menthol are antagonists of human 5-HT3receptors: implications for treating gastrointestinal disorders
Q44993960New roles of serotonin and tachykinins in intestinal mucositis?
Q36543489Partial agonism of 5-HT3 receptors: a novel approach to the symptomatic treatment of IBS-D
Q34804110Predominant mucosal expression of 5-HT₄(+h) receptor splice variants in pig stomach and colon.
Q42201240Prolonged inhibition of 5-HT₃ receptors by palonosetron results from surface receptor inhibition rather than inducing receptor internalization
Q58915076Serotonin receptors in hippocampus
Q37117442The 5-HT3AB receptor shows an A3B2 stoichiometry at the plasma membrane.
Q30486732The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.
Q47855566The Human Serotonin Type 3 Receptor Gene (HTR3A-E) Allelic Variant Database
Q39461570Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model