PPAR(gamma) and glucose homeostasis

scientific article

PPAR(gamma) and glucose homeostasis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1146/ANNUREV.NUTR.22.010402.102808
P698PubMed publication ID12055342

P50authorJohan AuwerxQ28468898
P2093author name stringFrédéric Picard
P2860cites workDominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertensionQ22011018
Ligand type-specific interactions of peroxisome proliferator-activated receptor gamma with transcriptional coactivatorsQ28143758
P407language of work or nameEnglishQ1860
P304page(s)167-197
P577publication date2002-01-04
P1433published inAnnual Review of NutritionQ4769675
P1476titlePPAR(gamma) and glucose homeostasis
P478volume22

Reverse relations

cites work (P2860)
Q27677636(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice
Q55073632A PPARγ, NF-κB and AMPK-dependent mechanism may be involved in the beneficial effects of curcumin in the diabetic db/db mice liver.
Q35072984A randomized, double blind, cross-over, placebo-controlled clinical trial to assess the effects of Candesartan on the insulin sensitivity on non diabetic, non hypertense subjects with dysglyce mia and abdominal obesity. "ARAMIA"
Q35009877A small volatile bacterial molecule triggers mitochondrial dysfunction in murine skeletal muscle
Q64057208Abdominal Fat SIRT6 Expression and Its Relationship with Inflammatory and Metabolic Pathways in Pre-Diabetic Overweight Patients
Q44980680Actions of PPARgamma agonism on adipose tissue remodeling, insulin sensitivity, and lipemia in absence of glucocorticoids.
Q47952464Activation of peroxisome proliferator-activated receptor γ prolongs islet allograft survival
Q40256198Altered PPARgamma expression inhibits myogenic differentiation in C2C12 skeletal muscle cells
Q28075617Alzheimer Disease: Crosstalk between the Canonical Wnt/Beta-Catenin Pathway and PPARs Alpha and Gamma
Q39483579Angiotensin II receptor blockade and insulin sensitivity in overweight and obese adults with elevated blood pressure
Q83319006Anti-inflammatory and anti-hyperlipidemic effect of Semecarpus anacardium in a high fat diet: STZ-induced type 2 diabetic rat model
Q91896482Antimetabolic Syndrome Effect of Phytosome Containing the Combined Extracts of Mulberry and Ginger in an Animal Model of Metabolic Syndrome
Q36142671Association of NCOA3 polymorphisms with Dyslipidemia in the Chinese Han population
Q73568159Benzoxazinones as PPARgamma agonists. part 1: SAR of three aromatic regions
Q37200544Beyond the classic angiotensin-receptor-blocker profile
Q42812731Caspase-mediated degradation of PPARgamma proteins in adipocytes
Q38809993Chemical and Physical Approaches to Extend the Replicative and Differentiation Potential of Stem Cells
Q34386587Clinical effectiveness of telmisartan alone or in combination therapy for controlling blood pressure and vascular risk in the elderly
Q45183730Common polymorphisms of the PPAR-gamma2 (Pro12Ala) and PGC-1alpha (Gly482Ser) genes are associated with the conversion from impaired glucose tolerance to type 2 diabetes in the STOP-NIDDM trial
Q39367068Comparative molecular profiling of the PPARα/γ activator aleglitazar: PPAR selectivity, activity and interaction with cofactors
Q41851511Comparative prophylactic effects of α-eleostearic acid rich nano and conventional emulsions in induced diabetic rats.
Q33717836Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPAR gamma hypomorphic mice
Q34195708Conjugated Linoleic Acid in Humans: Regulation of Adiposity and Insulin Sensitivity
Q34427072Coronary microvascular dysfunction in diabetes mellitus: A review
Q58699640Curcumin, Cardiometabolic Health and Dementia
Q56378075Daily Rhythms of TNFα Expression and Food Intake Regulate Synchrony of Plasmodium Stages with the Host Circadian Cycle
Q34197789Developmental programming: differential effects of prenatal testosterone excess on insulin target tissues
Q37973874Does interference with the renin-angiotensin system protect against diabetes? Evidence and mechanisms
Q47368574ESR1, FTO, and UCP2 genes interact with bariatric surgery affecting weight loss and glycemic control in severely obese patients.
Q46124638Effect of BSA-induced ER stress on SGLT protein expression levels and alpha-MG uptake in renal proximal tubule cells
Q36820428Effect of Opuntia humifusa supplementation and acute exercise on insulin sensitivity and associations with PPAR-γ and PGC-1α protein expression in skeletal muscle of rats
Q46906733Effect of alpha-tocopherol and beta-carotene supplementation on the incidence of type 2 diabetes
Q43247258Effect of peroxisome proliferator-activated receptor gamma agonists on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts
Q36642651Effective treatment of hypertension by AT(1) receptor antagonism: the past and future of telmisartan
Q35498269Effects of CP-900691, a novel peroxisome proliferator-activated receptor α, agonist on diabetic nephropathy in the BTBR ob/ob mouse
Q46293996Effects of cannabidiol interactions with Wnt/β-catenin pathway and PPARγ on oxidative stress and neuroinflammation in Alzheimer's disease
Q33727061Effects of the PPARgamma agonist pioglitazone on lipoprotein metabolism in patients with type 2 diabetes mellitus
Q36905154Effects of thiazolidinediones on blood pressure
Q36556337Electroacupuncture Reduces Weight Gain Induced by Rosiglitazone through PPARγ and Leptin Receptor in CNS
Q34166268Enhanced bone formation in lipodystrophic PPARgamma(hyp/hyp) mice relocates haematopoiesis to the spleen
Q44559508Enhancement of BRCA1 gene expression by the peroxisome proliferator-activated receptor gamma in the MCF-7 breast cancer cell line
Q38058381Examining the safety of PPAR agonists - current trends and future prospects
Q37106685Expression of peroxisome proliferator-activated receptor-gamma in key neuronal subsets regulating glucose metabolism and energy homeostasis
Q43165737Fasting promotes the expression of SIRT1, an NAD+ -dependent protein deacetylase, via activation of PPARalpha in mice.
Q37662234Fetal growth restriction, catch-up growth and the early origins of insulin resistance and visceral obesity.
Q38516045Functional genomic analysis reveals cross-talk between peroxisome proliferator-activated receptor gamma and calcium signaling in human colorectal cancer cells
Q36476832Gender, body mass index, and PPARγ polymorphism are good indicators in hyperuricemia prediction for Han Chinese
Q33902018Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome
Q36846922Genomic profiling in nuclear receptor-mediated toxicity
Q36447407Human immunodeficiency virus (HIV)-1 viral protein R suppresses transcriptional activity of peroxisome proliferator-activated receptor {gamma} and inhibits adipocyte differentiation: implications for HIV-associated lipodystrophy
Q39150404Hypoxia downregulates PPARγ via an ERK1/2-NF-κB-Nox4-dependent mechanism in human pulmonary artery smooth muscle cells
Q24629323Hypoxia-inducible factors and the response to hypoxic stress
Q35237706Identification of a novel selective agonist of PPARγ with no promotion of adipogenesis and less inhibition of osteoblastogenesis
Q38300981Improvement of metabolic syndrome by irbesartan via the PPARγ/HGF pathway in apolipoprotein E knockout mice
Q36973729In vivo and in vitro studies of a functional peroxisome proliferator-activated receptor gamma response element in the mouse pdx-1 promoter
Q90274032Induction of peroxisome proliferator activated receptor γ (PPARγ) mediated gene expression and inhibition of induced nitric oxide production by Maerua subcordata (Gilg) DeWolf
Q39030513Integrated proteomic and metabolomic analysis to assess the effects of pure and benzo[a]pyrene-loaded carbon black particles on energy metabolism and motility in the human endothelial cell line EA.hy926.
Q39180889Interactions between PPAR Gamma and the Canonical Wnt/Beta-Catenin Pathway in Type 2 Diabetes and Colon Cancer.
Q36512559Investigational PPAR-gamma agonists for the treatment of Type 2 diabetes
Q35753591Irbesartan for the treatment of hypertension in patients with the metabolic syndrome: a sub analysis of the Treat to Target post authorization survey. Prospective observational, two armed study in 14,200 patients
Q36267934Is there an estrogenic component in the metabolic syndrome?
Q38205763Knockout mouse models of insulin signaling: Relevance past and future
Q93090203Label-free quantitative proteomics identifies transforming growth factor β1 (TGF-β1) as an inhibitor of adipogenic transformation in OP9-DL1 cells and primary thymic stromal cells
Q34835012Liver-specific disruption of PPARgamma in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes
Q34216543Lysophosphatidic acid signaling: how a small lipid does big things
Q33642155MBX-102/JNJ39659100, a novel peroxisome proliferator-activated receptor-ligand with weak transactivation activity retains antidiabetic properties in the absence of weight gain and edema
Q35794061Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
Q37008855Macrophage peroxisome proliferator activated receptor gamma as a therapeutic target to combat Type 2 diabetes
Q80501209Metabolic action of peroxisome proliferator-activated receptor gamma agonism in rats with exogenous hypercorticosteronemia
Q33347137Metabolic actions of estrogen receptor beta (ERbeta) are mediated by a negative cross-talk with PPARgamma
Q36223165Molecular-specific effects of angiotensin II antagonists: clinical relevance to treating hypertension?
Q24561401Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review
Q34286456Nonhuman primates and other animal models in diabetes research
Q46750257Norepinephrine- and epinephrine-deficient mice gain weight normally on a high-fat diet.
Q35204071Nutrigenetics: where next for the foods industry?
Q43050364Obesity and insulin resistance-related changes in the expression of lipogenic and lipolytic genes in morbidly obese subjects.
Q37464644On the mechanism for PPAR agonists to enhance ABCA1 gene expression
Q35215073Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program
Q55457391Opposite Interplay Between the Canonical WNT/β-Catenin Pathway and PPAR Gamma: A Potential Therapeutic Target in Gliomas.
Q36465006PPAR Gamma: Coordinating Metabolic and Immune Contributions to Female Fertility.
Q46314621PPAR-gamma-independent inhibitory effect of rosiglitazone on glucose synthesis in primary cultured rabbit kidney-cortex tubules.
Q25255001PPAR-gamma: a thrifty transcription factor
Q28507952PPARalpha governs glycerol metabolism
Q28574968PPARgamma agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control
Q37215869PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease
Q35200033PPARgamma and metabolism: insights from the study of human genetic variants
Q43264778PPARgamma expression after a high-fat meal is associated with plasma superoxide dismutase activity in morbidly obese persons.
Q36063081PPARgamma in human and mouse physiology
Q50709371PPARγ activation regulates lipid droplet formation and lactate production in rat Sertoli cells.
Q44612931PPARγ activation, by reducing oxidative stress, increases NO bioavailability in coronary arterioles of mice with Type 2 diabetes
Q47633405Peroxisome proliferator activated receptor (PPAR)-gamma concentrations in childhood obesity
Q43182141Peroxisome proliferator-activated receptor gamma depletion stimulates Nox4 expression and human pulmonary artery smooth muscle cell proliferation
Q36018557Peroxisome proliferator-activated receptor gamma: the more the merrier?
Q34165847Peroxisome proliferator-activated receptor-gamma: too much of a good thing causes harm
Q33993320Pharmacogenomics of oral antidiabetic medications: current data and pharmacoepigenomic perspective
Q37053886Pharmacology and new perspectives of angiotensin II receptor blocker in prostate cancer treatment
Q92084186Pioglitazone improves phagocytic activity of liver recruited macrophages in elderly mice possibly by promoting glucose catabolism
Q46755499Placental restriction of fetal growth decreases IGF1 and leptin mRNA expression in the perirenal adipose tissue of late gestation fetal sheep.
Q42483651Plasminogen activator inhibitor-1 modulates adipocyte differentiation.
Q50988205Pleiotropic effects of thiazolidinediones: implications for the treatment of patients with type 2 diabetes mellitus.
Q34797066Polyunsaturated Fatty Acids Modulate the Association between PIK3CA-KCNMB3 Genetic Variants and Insulin Resistance
Q44414175Prevention of autoimmune diabetes in NOD mice by troglitazone is associated with modulation of ICAM-1 expression on pancreatic islet cells and IFN-γ expression in splenic T cells
Q85661680Prevention of metabolic disorders with telmisartan and indapamide in a Chinese population with high-normal blood pressure
Q35933720Prevention of type 2 diabetes mellitus through inhibition of the Renin-Angiotensin system
Q48375562Protective effect of telmisartan on neurovascular unit and inflammasome in stroke-resistant spontaneously hypertensive rats.
Q97644595Redox Regulation of PPARγ in Polarized Macrophages
Q35731006Regulation of SREBPs by Sphingomyelin in Adipocytes via a Caveolin and Ras-ERK-MAPK-CREB Signaling Pathway
Q39548383Regulation of androgen receptor expression through angiotensin II type 1 receptor in prostate cancer cells
Q42961710Relationship among superoxide-related enzyme, PPARs, and endothelium-dependent relaxation in murine aortas previously organ-cultured in high-glucose conditions
Q36020654Renin-angiotensin system inhibition prevents type 2 diabetes mellitus. Part 2. Overview of physiological and biochemical mechanisms
Q28299087Retinoid X receptors: X-ploring their (patho)physiological functions
Q36426752Role of the peroxisome proliferator-activated receptors, adenosine monophosphate-activated kinase, and adiponectin in the ovary
Q36581133Rosiglitazone Use and the Risk of Bladder Cancer in Patients With Type 2 Diabetes.
Q51346715SIRT1 interacts with metabolic transcriptional factors in the pancreas of insulin-resistant and calorie-restricted rats.
Q36772301Selective Modulators of PPAR-gamma Activity: Molecular Aspects Related to Obesity and Side-Effects
Q35860302Selective targeting of PPARγ by the natural product chelerythrine with a unique binding mode and improved antidiabetic potency
Q42437036Silencing Jnk1 and Jnk2 accelerates basal lipolysis and promotes fatty acid re-esterification in mouse adipocytes
Q24303857Sirtuin functions in health and disease
Q36911415Sirtuins: the 'magnificent seven', function, metabolism and longevity
Q37683351Slit diaphragm protein Neph1 and its signaling: a novel therapeutic target for protection of podocytes against glomerular injury
Q40650094Soy Isoflavones Exert Antidiabetic and Hypolipidemic Effects through the PPAR Pathways in Obese Zucker Rats and Murine RAW 264.7 Cells
Q39447694Stimulation of glucose uptake and improvement of insulin resistance by aromadendrin
Q27677426Structural basis for telmisartan-mediated partial activation of PPAR gamma
Q42478364Study of a new PPARgamma2 promoter polymorphism and haplotype analysis in a French population
Q42829800Suppression of PPAR-gamma attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes
Q27649827T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor gamma binding properties
Q91897242TGF-β in fibrosis by acting as a conductor for contractile properties of myofibroblasts
Q80101963Telmisartan, an angiotensin II type 1 receptor blocker, controls progress of nonalcoholic steatohepatitis in rats
Q37955284Telmisartan: just an antihypertensive agent? A literature review
Q38788726The Androgen Receptor Regulates PPARγ Expression and Activity in Human Prostate Cancer Cells
Q42007043The Effect of PPARalpha, PPARdelta, PPARgamma, and PPARpan Agonists on Body Weight, Body Mass, and Serum Lipid Profiles in Diet-Induced Obese AKR/J Mice
Q42818891The effect of plasminogen activator inhibitor-1 -675 4G/5G polymorphism on PAI-1 gene expression and adipocyte differentiation
Q36328060The effects of old, new and emerging medicines on metabolic aberrations in PCOS.
Q35592289The human sirtuin family: evolutionary divergences and functions.
Q38139508The importance of synthetic drugs for type 2 diabetes drug discovery
Q38727651The peroxisome proliferator-activated receptors under epigenetic control in placental metabolism and fetal development.
Q37029352The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications
Q37596557The role of sirtuins in the control of metabolic homeostasis
Q37848841The safety of thiazolidinediones
Q33748280Thermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma
Q39239818Thermodynamics in cancers: opposing interactions between PPAR gamma and the canonical WNT/beta-catenin pathway
Q35606054Thiazolidinediones and Fertility in Polycystic Ovary Syndrome (PCOS).
Q46275858Tissue-specific postprandial clearance is the major determinant of PPARgamma-induced triglyceride lowering in the rat.
Q38344277Transcription factors and cognate signalling cascades in the regulation of autophagy
Q48177278Treatment with Parkinsonia aculeata combats insulin resistance-induced oxidative stress through the increase in PPARγ/CuZn-SOD axis expression in diet-induced obesity mice.
Q91639799Two antibacterial and PPARα/γ-agonistic unsaturated keto fatty acids from a coral-associated actinomycete of the genus Micrococcus
Q46830855Up-regulation of PPARgamma in myocardial infarction
Q65001385Withaferin A inhibits adipogenesis in 3T3-F442A cell line, improves insulin sensitivity and promotes weight loss in high fat diet-induced obese mice.
Q90214862p-21 Activated Kinase as a Molecular Target for Chemoprevention in Diabetes
Q37093109α-linolenic acid inhibits human renal cell carcinoma cell proliferation through PPAR-γ activation and COX-2 inhibition

Search more.