(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice

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(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice is …
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scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...731811Z
P356DOI10.1371/JOURNAL.PONE.0031811
P932PMC publication ID3288053
P698PubMed publication ID22384078
P5875ResearchGate publication ID221882678

P50authorMingyue ZhengQ43370955
P2093author name stringYu Zhang
Jing Chen
Lili Chen
Haitao Zhang
Hong Shen
Hualiang Jiang
Xu Shen
Lihong Hu
Chenjing Li
Jiming Ye
Xin-Gang Yao
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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocationQ24322925
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PROCHECK: a program to check the stereochemical quality of protein structuresQ26778411
Development of a novel GLUT4 translocation assay for identifying potential novel therapeutic targets for insulin sensitizationQ46227047
Retinoic acids increase expression of GLUT4 in dedifferentiated and hypertrophied cardiac myocytesQ46793314
The dipeptide H-Trp-Glu-OH shows highly antagonistic activity against PPARgamma: bioassay with molecular modeling simulationQ46827814
Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.Q52540333
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Differential interaction of steroid hormone receptors with LXXLL motifs in SRC-1a depends on residues flanking the motifQ73580687
Transcriptional regulation of the GLUT4 gene: from PPAR-gamma and FOXO1 to FFA and inflammationQ79817052
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PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase geneQ28618806
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Metabolic effects of rexinoids: tissue-specific regulation of lipoprotein lipase activity.Q31843161
Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4).Q34206633
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PTP1B as a drug target: recent developments in PTP1B inhibitor discoveryQ36805716
Ins (endocytosis) and outs (exocytosis) of GLUT4 traffickingQ36888387
Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targetingQ37598771
Insulin-responsive compartments containing GLUT4 in 3T3-L1 and CHO cells: regulation by amino acid concentrationsQ39460118
Metformin induces Rab4 through AMPK and modulates GLUT4 translocation in skeletal muscle cellsQ39653292
Farnesoid X receptor induces GLUT4 expression through FXR response element in the GLUT4 promoterQ39943738
Suppression of prostate tumor cell growth by stromal cell prostaglandin D synthase-derived productsQ40396841
Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific mannerQ40730870
Tyrosine phosphatase inhibitors, vanadate and pervanadate, stimulate glucose transport and GLUT translocation in muscle cells by a mechanism independent of phosphatidylinositol 3-kinase and protein kinase C.Q40999272
GLUT4 translocation by insulin in intact muscle cells: detection by a fast and quantitative assayQ41038402
Retinoic acid stimulates glucose transporter expression in L6 muscle cellsQ41367863
Evidence for the involvement of vicinal sulfhydryl groups in insulin-activated hexose transport by 3T3-L1 adipocytes.Q42225038
Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alphaQ42447473
Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitizationQ42818292
Demonstration of insulin-responsive trafficking of GLUT4 and vpTR in fibroblastsQ42834482
PGC-1{alpha} is required for AICAR-induced expression of GLUT4 and mitochondrial proteins in mouse skeletal muscleQ42971374
Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effectQ44460156
Allosteric inhibition of protein tyrosine phosphatase 1B.Q44982496
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectglucoseQ37525
insulin resistanceQ1053470
preproinsulinQ7240673
P304page(s)e31811
P577publication date2012-02-27
P1433published inPLOS OneQ564954
P1476title(+)-Rutamarin as a dual inducer of both GLUT4 translocation and expression efficiently ameliorates glucose homeostasis in insulin-resistant mice
P478volume7

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Q37544369Antiviral activity of (+)-rutamarin against Kaposi's sarcoma-associated herpesvirus by inhibition of the catalytic activity of human topoisomerase II.
Q44017161Chalepin: A Compound from Ruta angustifolia L. Pers Exhibits Cell Cycle Arrest at S phase, Suppresses Nuclear Factor-Kappa B (NF-κB) Pathway, Signal Transducer and Activation of Transcription 3 (STAT3) Phosphorylation and Extrinsic Apoptotic Pathway
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Q38313005Latanoprost effectively ameliorates glucose and lipid disorders in db/db and ob/ob mice
Q34499394Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception.
Q38694918Rutamarin, an Active Constituent from Ruta angustifolia Pers., Induced Apoptotic Cell Death in the HT29 Colon Adenocarcinoma Cell Line

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