Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect

scientific article published on 29 May 2003

Peroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M304654200
P698PubMed publication ID12777391

P50authorMichael J. QuonQ42818051
Fabiana Bar-YosephQ125314218
Eddy KarnieliQ125314258
P2093author name stringHui Chen
Chava Harel
Michal Armoni
Natalia Kritz
P2860cites workTransfection of DNA into isolated rat adipose cells by electroporation: evaluation of promoter activity in transfected adipose cells which are highly responsive to insulin after one day in cultureQ43509513
Chromosomal Localization and Partial Genomic Structure of the Human Peroxisome Proliferator Activated Receptor-Gamma (hPPARγ) GeneQ57242021
Peroxisome proliterator-activated receptors, orphans with ligands and functionsQ57244375
Insulin stimulation of GLUT-4 translocation: a model for regulated recyclingQ58480883
Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertensionQ22011018
The organization, promoter analysis, and expression of the human PPARgamma geneQ28244071
15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gammaQ29615221
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)Q29615693
mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancerQ29617271
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiationQ29619212
PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistanceQ29622888
RosiglitazoneQ33684266
Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1.Q33967999
PPAR-gamma agonists: therapeutic role in diabetes, inflammation and cancerQ34106716
Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4).Q34206633
A possible mechanism of insulin resistance in the rat adipose cell in streptozotocin-induced diabetes mellitus. Depletion of intracellular glucose transport systemsQ37003611
Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiencyQ37175466
Pioglitazone induces in vivo adipocyte differentiation in the obese Zucker fa/fa rat.Q38343197
Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinaseQ38346718
PAX3/forkhead homolog in rhabdomyosarcoma oncoprotein activates glucose transporter 4 gene expression in vivo and in vitro.Q40692581
Facilitative glucose transportersQ40717146
A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma-mediated adipogenesisQ40899355
Glucose transport and NIDDMQ41115289
Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgammaQ41144553
Regulation of GLUT4 gene expression by arachidonic acid. Evidence for multiple pathways, one of which requires oxidation to prostaglandin E2.Q41239821
TroglitazoneQ41521276
Peroxisome proliferator activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more....Q41651418
Reversal of insulin resistance in diabetic rat adipocytes by insulin therapy. Restoration of pool of glucose transporters and enhancement of glucose-transport activityQ42516879
Sex differences in insulin action on glucose transport and transporters in human omental adipocytesQ42517461
P433issue33
P407language of work or nameEnglishQ1860
P921main subjectadipocyteQ357519
(RS)-rosiglitazoneQ424771
P304page(s)30614-30623
P577publication date2003-05-29
P1433published inJournal of Biological ChemistryQ867727
P1476titlePeroxisome proliferator-activated receptor-gamma represses GLUT4 promoter activity in primary adipocytes, and rosiglitazone alleviates this effect
P478volume278

Reverse relations

cites work (P2860)
Q27677636(+)-Rutamarin as a Dual Inducer of Both GLUT4 Translocation and Expression Efficiently Ameliorates Glucose Homeostasis in Insulin-Resistant Mice
Q28741502A potential role for glucose transporters in the evolution of human brain size
Q24305362Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}
Q42469480An angiotensin II AT1 receptor antagonist, telmisartan augments glucose uptake and GLUT4 protein expression in 3T3-L1 adipocytes.
Q38338967Chicken ovalbumin upstream promoter-transcription factor II regulates nuclear receptor, myogenic, and metabolic gene expression in skeletal muscle cells.
Q34452611Class II histone deacetylases limit GLUT4 gene expression during adipocyte differentiation
Q46288858Contractile activity per se induces transcriptional activation of SLC2A4 gene in soleus muscle: involvement of MEF2D, HIF-1a, and TRalpha transcriptional factors
Q28508812Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes
Q39209941Cross-Talk between PPARgamma and Insulin Signaling and Modulation of Insulin Sensitivity
Q40522050Cytosolic phospholipase A2 Group IValpha but not secreted phospholipase A2 Group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors gamma 1 and 2 in human lung cell
Q54318425Deficiency in the NADPH oxidase 4 predisposes towards diet-induced obesity.
Q39077948Di(2-ethylhexyl)phthalate exposure impairs insulin receptor and glucose transporter 4 gene expression in L6 myotubes
Q34395184Effect of rosiglitazone on HDL metabolism in subjects with metabolic syndrome and low HDL.
Q47696836Electroacupuncture plus metformin lowers glucose levels and facilitates insulin sensitivity by activating MAPK in steroid-induced insulin-resistant rats.
Q90522413Ellagic Acid and Urolithins A and B Differentially Regulate Fat Accumulation and Inflammation in 3T3-L1 Adipocytes While Not Affecting Adipogenesis and Insulin Sensitivity
Q38726891Evidences for diabetes and insulin mimetic activity of medicinal plants: Present status and future prospects
Q47621226Exposure of Pregnant Mice to Triclosan Causes Insulin Resistance via Thyroxine Reduction
Q36164341FABP4-Cre Mediated Expression of Constitutively Active ChREBP Protects Against Obesity, Fatty Liver, and Insulin Resistance
Q37129794FOXO-binding partners: it takes two to tango
Q40237087Farnesyl pyrophosphate regulates adipocyte functions as an endogenous PPARγ agonist.
Q38322283Free fatty acids repress the GLUT4 gene expression in cardiac muscle via novel response elements
Q49911816GQ-11: A new PPAR agonist improves obesity-induced metabolic alterations in LDLr-/- mice.
Q35842591Galectin-3 deficiency exacerbates hyperglycemia and the endothelial response to diabetes
Q37030803Gender-specific differences in PPARγ regulation of follicular helper T cell responses with estrogen
Q41094311HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning
Q45205488Improved insulin sensitivity and adipose tissue dysregulation after short-term treatment with pioglitazone in non-diabetic, insulin-resistant subjects
Q36250154Influence of different CLA isomers on insulin resistance and adipocytokines in pre-diabetic, middle-aged men with PPARγ2 Pro12Ala polymorphism
Q93039454Insulin-independent stimulation of skeletal muscle glucose uptake by low-dose abscisic acid via AMPK activation
Q37368638Isomer-specific effects of CLA on gene expression in human adipose tissue depending on PPARgamma2 P12A polymorphism: a double blind, randomized, controlled cross-over study
Q39059715Mechanisms regulating GLUT4 transcription in skeletal muscle cells are highly conserved across vertebrates
Q42109973PPARgamma regulates adipocyte cholesterol metabolism via oxidized LDL receptor 1
Q24642728PPARs and the cardiovascular system
Q42504144Peroxisome proliferator activated receptor gamma activity is low in mature primary human visceral adipocytes
Q38633502Peroxisome proliferator-activated receptors and hepatitis C virus
Q35039274Pharmacogenomics and pharmacogenetics of thiazolidinediones: role in diabetes and cardiovascular risk factors
Q38205765Phytotherapy in diabetes: Review on potential mechanistic perspectives
Q37377433Posttranslational modifications of PPAR-gamma: fine-tuning the metabolic master regulator
Q38809165Potent PPARγ Ligands from Swietenia macrophylla Are Capable of Stimulating Glucose Uptake in Muscle Cells.
Q39062062Prevention of nutritionally induced diabetes by rosiglitazone in the gerbil Psammomys obesus
Q98952064Progesterone receptor membrane associated component 1 enhances obesity progression in mice by facilitating lipid accumulation in adipocytes
Q36093005Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes
Q34114146Rare mutations of peroxisome proliferator-activated receptor gamma: frequencies and relationship with insulin resistance and diabetes risk in the mixed ancestry population from South Africa.
Q37025897Rosiglitazone : a review of its use in type 2 diabetes mellitus.
Q38893734Signaling pathways involved in cardiac energy metabolism
Q42423820Somatic cell plasticity and Niemann-pick type C2 protein: adipocyte differentiation and function
Q57124524Study of the effect of the herbal composition SR2004 on hemoglobin A1c, fasting blood glucose, and lipids in patients with type 2 diabetes mellitus
Q34514818Targeting Forkhead box O1 from the concept to metabolic diseases: lessons from mouse models
Q58798692The Effect of L. Fruit Juice on the Blood Sugar Level and Other Serum Parameters in Patients with Diabetes Type 2
Q38727651The peroxisome proliferator-activated receptors under epigenetic control in placental metabolism and fetal development.
Q37168807Transcriptional regulation of the insulin-responsive glucose transporter GLUT4 gene: from physiology to pathology
Q33802801Uteroplacental insufficiency increases visceral adiposity and visceral adipose PPARgamma2 expression in male rat offspring prior to the onset of obesity
Q35172969Zinc finger protein 407 (ZFP407) regulates insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) mRNA

Search more.