Identification of two major conformational aquaporin-4 epitopes for neuromyelitis optica autoantibody binding

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Identification of two major conformational aquaporin-4 epitopes for neuromyelitis optica autoantibody binding is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M110.123000
P932PMC publication ID3059066
P698PubMed publication ID21212277

P2093author name stringAndrea Rossi
Antonio Frigeri
Grazia Paola Nicchia
Maria Svelto
Maria Trojano
Francesco Pisani
Carla Tortorella
Maddalena Ruggieri
Mauro Mastrototaro
P2860cites workActivation of humoral immunity and eosinophils in neuromyelitis opticaQ81208760
Western blot analysis for the detection of serum antibodies recognizing linear Aquaporin-4 epitopes in patients with Neuromyelitis OpticaQ84768754
Neuromyelitis optica pathogenesis and aquaporin 4Q21245240
IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channelQ24646531
Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductanceQ24648744
A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosisQ29615952
Aquaporin-4 dynamics in orthogonal arrays in live cells visualized by quantum dot single particle trackingQ30482870
Anti-aquaporin-4 antibody is involved in the pathogenesis of NMO: a study on antibody titre.Q31110030
Aquaporin-4-binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2.Q36946523
Anti-aquaporin-4 auto-antibodies orchestrate the pathogenesis in neuromyelitis opticaQ37457250
The channel architecture of aquaporin 0 at a 2.2-A resolutionQ37557408
Neurological autoimmunity targeting aquaporin-4.Q37584448
Evidences for a leaky scanning mechanism for the synthesis of the shorter M23 protein isoform of aquaporin-4: implication in orthogonal array formation and neuromyelitis optica antibody interactionQ39539421
Prediction of neuromyelitis optica attack severity by quantitation of complement-mediated injury to aquaporin-4-expressing cells.Q39799856
Aquaporin-4 orthogonal arrays of particles are the target for neuromyelitis optica autoantibodiesQ39881740
Heterogeneity of aquaporin-4 autoimmunity and spinal cord lesions in multiple sclerosis in JapaneseQ40144678
Implications of the aquaporin-4 structure on array formation and cell adhesion.Q40344417
Identification of new serum autoantibodies in neuromyelitis optica using protein microarraysQ46517141
Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissuesQ46744705
Identification of binding sites for anti-aquaporin 4 antibodies in patients with neuromyelitis opticaQ47896650
Loss of aquaporin 4 in lesions of neuromyelitis optica: distinction from multiple sclerosisQ48219268
Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosisQ48282187
Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain.Q48823528
Detection of brain-specific autoantibodies to myelin oligodendrocyte glycoprotein, S100beta and myelin basic protein in patients with Devic's neuromyelitis optica.Q48828808
Incorporation of proteins into (Xenopus) oocytes by proteoliposome microinjection: functional characterization of a novel aquaporin.Q48986764
Neuromyelitis optica and non organ-specific autoimmunityQ80492828
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectneuromyelitis opticaQ611458
autoantibodyQ785022
P304page(s)9216-9224
P577publication date2011-01-06
P1433published inJournal of Biological ChemistryQ867727
P1476titleIdentification of two major conformational aquaporin-4 epitopes for neuromyelitis optica autoantibody binding
P478volume286

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cites work (P2860)
Q91151770A highly specific and sensitive nanoimmunosensor for the diagnosis of neuromyelitis optica spectrum disorders
Q37069746A novel monoclonal antibody against the C-terminal region of aquaporin-4
Q34631897AQP4-dependent water transport plays a functional role in exercise-induced skeletal muscle adaptations
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Q37066291Aquaporin water channels in the nervous system.
Q38151920Aquaporin-4 antibodies (NMO-IgG) as a serological marker of neuromyelitis optica: a critical review of the literature
Q35048235Aquaporin-4 autoantibodies in Neuromyelitis Optica: AQP4 isoform-dependent sensitivity and specificity
Q36431376Astrocytic autoantibody of neuromyelitis optica (NMO-IgG) binds to aquaporin-4 extracellular loops, monomers, tetramers and high order arrays
Q34377212Biology of AQP4 and anti-AQP4 antibody: therapeutic implications for NMO.
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Q97067655Comparative Analysis of T-Cell Responses to Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein in Inflammatory Demyelinating Central Nervous System Diseases
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Q60921343Comprehensive review of neuromyelitis optica and clinical characteristics of neuromyelitis optica patients in Puerto Rico
Q42126901Detection of anti-aquaporin-4 autoantibodies in the sera of Chinese neuromyelitis optica patients
Q35850484Development of an Aquaporin-4 Orthogonal Array of Particle-Based ELISA for Neuromyelitis Optica Autoantibodies Detection
Q34632417Discovery of peptoid ligands for anti-aquaporin 4 antibodies
Q50914847Functional Epitopes for Anti-Aquaporin 5 Antibodies in Sjögren Syndrome.
Q36744223High avidity chimeric monoclonal antibodies against the extracellular domains of human aquaporin-4 competing with the neuromyelitis optica autoantibody, NMO-IgG.
Q36778303High-Density Peptide Microarray Analysis of IgG Autoantibody Reactivities in Serum and Cerebrospinal Fluid of Multiple Sclerosis Patients.
Q64244586Host-Cell Type Dependent Features of Recombinant Human Aquaporin-4 Orthogonal Arrays of Particles-New Insights for Structural and Functional Studies
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Q35583116Mutagenesis of the aquaporin 4 extracellular domains defines restricted binding patterns of pathogenic neuromyelitis optica IgG.
Q36650382Neuromyelitis optica IgG does not alter aquaporin-4 water permeability, plasma membrane M1/M23 isoform content, or supramolecular assembly
Q57725942Neuromyelitis optica should be classified as an astrocytopathic disease rather than a demyelinating disease
Q36911907Neuromyelitis optica: aquaporin-4 based pathogenesis mechanisms and new therapies
Q99568261Orthogonal arrays of particle assembly are essential for normal aquaporin-4 expression level in the brain
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Q48136223Response to 'The evolving mystery of why skeletal muscle is spared in seropositive neuromyelitis optica'.
Q47832841Supramolecular aggregation of aquaporin-4 is different in muscle and brain: correlation with tissue susceptibility in neuromyelitis optica.
Q41683003The binding property of a monoclonal antibody against the extracellular domains of aquaporin-4 directs aquaporin-4 toward endocytosis

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