Synthesis and antiviral activities of new acyclic and "double-headed" nucleoside analogues

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Synthesis and antiviral activities of new acyclic and "double-headed" nucleoside analogues is …
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scholarly articleQ13442814

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P356DOI10.1016/J.BIOORG.2006.11.003
P932PMC publication ID4265801
P698PubMed publication ID17270235

P50authorErik De ClercqQ13578863
Johan NeytsQ29460378
Mark PrichardQ58209295
Adel AmerQ60607551
Earl R. KernQ94159830
Paul F TorrenceQ116791662
Jan BalzariniQ31332118
P2093author name stringEarl Kern
Xinying Zhang
Xuesen Fan
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Assembling a smallpox biodefense by interrogating 5-substituted pyrimidine nucleoside chemical spaceQ83945005
A cyclic dinucleotide with a four-carbon 5'-C-to-5'-C connection; synthesis by RCM, NMR-examination and incorporation into secondary nucleic acid structuresQ83956479
New class of orthopoxvirus antiviral drugs that block viral maturationQ33208347
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Antiviral chemotherapy facilitates control of poxvirus infections through inhibition of cellular signal transductionQ33777888
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Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activityQ34123595
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Treatment of aerosolized cowpox virus infection in mice with aerosolized cidofovirQ43485506
Role of acyclovir in the treatment of herpes simplex virus keratitis.Q43541581
Synthesis of double headed imidazoline acyclo C-nucleosides: 1,4-bis[1-amino-5-oxo-4-substituted(imidazolin-2-yl)]galacto-tetritolsQ44484102
Smallpox: a disease and a weaponQ44905889
First synthesis of double headed 1,3,4-oxadiazino[6,5-b]indole acyclo C-nucleosidesQ45208880
Cidofovir protects mice against lethal aerosol or intranasal cowpox virus challengeQ45745500
Stabilisation of nucleic acid secondary structures by oligonucleotides with an additional nucleobase; synthesis and incorporation of 2'-deoxy-2'-C-(2-(thymine-1-yl)ethyl)uridineQ46711813
Synthesis and antiviral activities of 1,2,3-triazole functionalized thymidines: 1,3-dipolar cycloaddition for efficient regioselective diversity generationQ46838514
Synthesis of cyclopentenyl carbocyclic nucleosides as potential antiviral agents against orthopoxviruses and SARS.Q46922553
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)221-232
P577publication date2006-12-02
P1433published inBioorganic ChemistryQ2904198
P1476titleSynthesis and antiviral activities of new acyclic and "double-headed" nucleoside analogues
P478volume35

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cites work (P2860)
Q59191034Lithium Bromide as a Mild, Efficient, and Recyclable Catalyst for the One-Pot Synthesis of Tetrahydro-4H-Chromene Derivatives in Aqueous Media
Q91816187Novel 5-substituted derivatives of 2'-deoxy-6-azauridine with antibacterial activity
Q53789282Triazolophthalazines: Easily Accessible Compounds with Potent Antitubercular Activity.

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