Lack of neuroprotection against experimental glaucoma in c-Jun N-terminal kinase 3 knockout mice

scientific article

Lack of neuroprotection against experimental glaucoma in c-Jun N-terminal kinase 3 knockout mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.EXER.2011.01.006
P932PMC publication ID3060951
P698PubMed publication ID21272576
P5875ResearchGate publication ID49790351

P50authorDonald J. ZackQ114257272
P2093author name stringZhiyong Yang
Harry A Quigley
Ericka N Oglesby
Frances E Cone
Janice L Son
Mary E Pease
Scott E Gelman
P2860cites workLasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury.Q42828653
Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J miceQ42914157
Differences in activation of ERK1/2 and p38 kinase in Jnk3 null mice following KA treatment.Q43037982
Role of the c-Jun N-terminal kinase pathway in retinal excitotoxicity, and neuroprotection by its inhibitionQ43117422
Immunohistochemical assessment of the glial mitogen-activated protein kinase activation in glaucomaQ44489818
Effect of glatiramer acetate on primary and secondary degeneration of retinal ganglion cells in the rat.Q45280864
Retinal ganglion cells downregulate gene expression and lose their axons within the optic nerve head in a mouse glaucoma model.Q46815689
Retrograde axonal degeneration "dieback" in the corticospinal tract after transection injury of the rat spinal cord: a confocal microscopy studyQ46984203
Breakdown of axonal synaptic vesicle precursor transport by microglial nitric oxide.Q49153806
Direct inhibition of c-Jun N-terminal kinase in sympathetic neurones prevents c-jun promoter activation and NGF withdrawal-induced deathQ51069152
Required roles of Bax and JNKs in central and peripheral nervous system death of retinoblastoma-deficient mice.Q53558288
Immunostaining of heat shock proteins in the retina and optic nerve head of normal and glaucomatous eyes.Q53913933
All JNKs Can Kill, but Nuclear Localization Is Critical for Neuronal DeathQ60701494
Injury-specific expression of activating transcription factor-3 in retinal ganglion cells and its colocalized expression with phosphorylated c-JunQ74150796
The JIP group of mitogen-activated protein kinase scaffold proteinsQ22010547
The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemiaQ28281092
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 geneQ28507982
Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesinQ30490028
JNK3 mediates paraquat- and rotenone-induced dopaminergic neuron deathQ30498929
The transcription factor c-jun is activated in retinal ganglion cells in experimental rat glaucomaQ31165680
The effect of experimental glaucoma and optic nerve transection on amacrine cells in the rat retinaQ33222316
Expression of phosphorylated c-Jun N-terminal protein kinase (JNK) in experimental glaucoma in ratsQ33224379
Regulation of cell death and survival pathways in experimental glaucomaQ33288597
Changes in gene expression in experimental glaucoma and optic nerve transection: the equilibrium between protective and detrimental mechanismsQ33308449
Ocular hypertension impairs optic nerve axonal transport leading to progressive retinal ganglion cell degenerationQ33511068
Differential susceptibility to experimental glaucoma among 3 mouse strains using bead and viscoelastic injectionQ34196101
Retrograde signaling in injured nerve--the axon reaction revisitedQ34555696
Calibration of the TonoLab tonometer in mice with spontaneous or experimental glaucomaQ34645725
Sunday Driver links axonal transport to damage signalingQ36321488
Specific activities of individual c-Jun N-terminal kinases in the brainQ37443237
Switching mature retinal ganglion cells to a robust growth state in vivo: gene expression and synergy with RhoA inactivation.Q38335683
Light damage induced changes in mouse retinal gene expressionQ38337441
Insulin activates CCAAT/enhancer binding proteins and proinflammatory gene expression through the phosphatidylinositol 3-kinase pathway in vascular smooth muscle cellsQ40714961
The major cell populations of the mouse retina.Q40838448
JNK2 and JNK3 combined are essential for apoptosis in dopamine neurons of the substantia nigra, but are not required for axon degenerationQ41939806
Cerebral ischemia provokes a profound exchange of activated JNK isoforms in brain mitochondriaQ42450951
P433issue4
P921main subjectknockout mouseQ1364740
P304page(s)299-305
P577publication date2011-01-25
P1433published inExperimental Eye ResearchQ15754753
P1476titleLack of neuroprotection against experimental glaucoma in c-Jun N-terminal kinase 3 knockout mice
P478volume92

Reverse relations

cites work (P2860)
Q34986464Activation of TLR3 promotes the degeneration of retinal ganglion cells by upregulating the protein levels of JNK3
Q50217093Effect of the M1 Muscarinic Acetylcholine Receptor on Retinal Neuron Number Studied with Gene-Targeted Mice
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Q90308827Inducible rodent models of glaucoma
Q37979549Intrinsic axonal degeneration pathways are critical for glaucomatous damage.
Q35228456JNK isoforms differentially regulate neurite growth and regeneration in dopaminergic neurons in vitro.
Q42030670JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell death
Q43107105JUN regulates early transcriptional responses to axonal injury in retinal ganglion cells
Q44876513KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS.
Q36827534Quantitative measurement of retinal ganglion cell populations via histology-based random forest classification
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Q88805962Targets of Neuroprotection in Glaucoma
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