Mechanisms of Amine Accumulation in, and Egress from, Lysosomes

scientific article published on November 1, 2009

Mechanisms of Amine Accumulation in, and Egress from, Lysosomes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4155/BIO.09.128
P953full work available at URLhttps://doi.org/10.4155/bio.09.128
https://europepmc.org/articles/PMC3065188
https://europepmc.org/articles/pmc3065188?pdf=render
https://europepmc.org/articles/PMC3065188?pdf=render
https://www.tandfonline.com/doi/pdf/10.4155/bio.09.128
P932PMC publication ID3065188
P698PubMed publication ID21083094
P5875ResearchGate publication ID47810504

P2093author name stringRoger A. Rajewski
Jeffrey P. Krise
Ryan S. Funk
Stephen D. B. Goldman
P2860cites workQuantitative modeling of selective lysosomal targeting for drug designQ24647940
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Drug-induced phospholipidosisQ28264054
Functions of lysosomesQ29614182
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Lysosomal trapping as an important mechanism involved in the cellular distribution of perazine and in pharmacokinetic interaction with antidepressantsQ33179423
Simulation-based cheminformatic analysis of organelle-targeted molecules: lysosomotropic monobasic aminesQ33323615
The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargoQ33856244
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Commentary. Lysosomotropic agentsQ34214505
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Drug-phospholipid interactions: role in aminoglycoside nephrotoxicityQ35748810
Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake into lysosomes of weakly basic substancesQ36205315
The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblastsQ36220506
Contribution of lysosomal trapping to the total tissue uptake of psychotropic drugsQ36849532
Interactions between promazine and antidepressants at the level of cellular distributionQ36895138
Functional intracellular P-glycoproteinQ36897086
Vesicular neurotransmitter transporters as targets for endogenous and exogenous toxic substancesQ36947112
A fluorescence resonance energy transfer-based approach for investigating late endosome-lysosome retrograde fusion eventsQ37216331
Cholesterol synthesis inhibitor U18666A and the role of sterol metabolism and trafficking in numerous pathophysiological processesQ37480847
Nephrotoxicity of aminoglycoside antibiotics.Q38616214
The concept of "aldehyde load" in neurodegenerative mechanisms: cytotoxicity of the polyamine degradation products hydrogen peroxide, acrolein, 3-aminopropanal, 3-acetamidopropanal and 4-aminobutanal in a retinal ganglion cell lineQ40158684
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Neurotoxicity of reactive aldehydes: the concept of "aldehyde load" as demonstrated by neuroprotection with hydroxylaminesQ40274730
A novel assay reveals that weakly basic model compounds concentrate in lysosomes to an extent greater than pH-partitioning theory would predictQ40344622
Niemann-Pick C1 protein facilitates the efflux of the anticancer drug daunorubicin from cells according to a novel vesicle-mediated pathwayQ40370825
A cell fractionation approach for the quantitative analysis of subcellular drug dispositionQ40585850
Lysosomal destabilization during macrophage damage induced by cholesterol oxidation productsQ40815836
Cerebral ischemia enhances polyamine oxidation: identification of enzymatically formed 3-aminopropanal as an endogenous mediator of neuronal and glial cell deathQ41023528
Photo-Oxidative Disruption of Lysosomal Membranes Causes Apoptosis of Cultured Human FibroblastsQ41138991
Intracellular localization, vesicular accumulation and kinetics of daunorubicin in sensitive and multidrug-resistant gastric carcinoma EPG85-257 cellsQ41393547
Passive diffusion of non-electrolytes across the lysosome membraneQ41813176
Role of the aclacinomycin A--doxorubicin association in reversal of doxorubicin resistance in K562 tumour cellsQ41843130
Massive cell vacuolization induced by organic amines such as procainamide.Q41914416
Selective lysosomal uptake and accumulation of the beta-adrenergic antagonist propranolol in cultured and isolated cell systemsQ41915565
The fate of ferriprotorphyrin IX in malaria infected erythrocytes in conjunction with the mode of action of antimalarial drugsQ41924267
Lysosomes, pH and the Anti-malarial Action of ChloroquineQ41935841
A multicompartmental model of fluid-phase endocytosis in rabbit liver parenchymal cellsQ41964897
3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxinQ42120400
Niemann-Pick C1 functions in regulating lysosomal amine contentQ42426518
Influence of lipophilicity and lysosomal accumulation on tissue distribution kinetics of basic drugs: a physiologically based pharmacokinetic modelQ44012650
Procaine-induced enhancement of fluid-phase endocytosis and inhibition of exocytosis in human skin fibroblastsQ44572468
Flux of fatty acids through NPC1 lysosomesQ45211605
Digestive activity of lysosomes. II. The digestion of macromolecular carbohydrates by extracts of rat liver lysosomes.Q45279481
A novel mechanism for regulation of vacuolar acidificationQ48420638
Quantitation of the lysosomotropic character of cationic amphiphilic drugs using the fluorescent basic amine Red DND-99.Q50801174
Lysosome membrane permeability to amines.Q52191771
Correlation between growth inhibition and intranuclear doxorubicin and 4'-deoxy-4'-iododoxorubicin quantitated in living K562 cells by microspectrofluorometry.Q52540041
The effects of osmotic pressure on procaine-induced vacuolation in cell culture.Q52748637
MECHANISM OF DRUG-INDUCED VACUOLIZATION IN TISSUE CULTURE.Q52760812
Digestive activity of lysosomes. 3. The digestion of lipids by extracts of rat liver lysosomes.Q54071061
Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblastsQ69131540
Structural and physical changes in lysosomes from isolated rat hepatocytes treated with methylamineQ71061761
Digestive activity of lysosomes. I. The digestion of proteins by extracts of rat liver lysosomesQ72059476
Organic cation transport by rat liver lysosomesQ72655333
P4510describes a project that usesImageJQ1659584
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)1445-1459
P577publication date2009-11-01
P1433published inBioanalysisQ18616741
P1476titleMechanisms of amine accumulation in, and egress from, lysosomes
Mechanisms of Amine Accumulation in, and Egress from, Lysosomes
P478volume1

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