Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells

scientific article

Transcriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.23.6.2123-2134.2003
P932PMC publication ID149482
P698PubMed publication ID12612083
P5875ResearchGate publication ID8107143

P2093author name stringRobert J Duronio
Pelin Cayirlioglu
S Catherine Silver Key
William O Ward
P2860cites workHeterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activationQ24318303
Mutations of the Drosophila dDP, dE2F, and cyclin E genes reveal distinct roles for the E2F-DP transcription factor and cyclin E during the G1-S transition.Q24533583
E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycleQ24563485
E2f3 is critical for normal cellular proliferationQ24608300
E2F-5, a new E2F family member that interacts with p130 in vivoQ24652329
E2F4 and E2F5 play an essential role in pocket protein-mediated G1 controlQ28141003
Notch-Delta signaling induces a transition from mitotic cell cycle to endocycle in Drosophila follicle cellsQ28208451
E2F-4, a new member of the E2F transcription factor family, interacts with p107Q28240565
E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivoQ28240575
The regulation of E2F by pRB-family proteinsQ28278789
The transcription factor E2F is required for S phase during Drosophila embryogenesisQ28292608
Sibling rivalry in the E2F familyQ29615056
E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis.Q33551291
The role of ACE3 in Drosophila chorion gene amplificationQ33590476
Chorion gene amplification in Drosophila: A model for metazoan origins of DNA replication and S-phase controlQ33716435
ORC binding, gene amplification, and the nature of metazoan replication originsQ33763154
The role of RBF in the introduction of G1 regulation during Drosophila embryogenesisQ33890435
E2F mediates developmental and cell cycle regulation of ORC1 in DrosophilaQ33890848
Amplification of the X-linked Drosophila chorion gene cluster requires a region upstream from the s38 chorion geneQ33929082
Drosophila minichromosome maintenance 6 is required for chorion gene amplification and genomic replicationQ33953738
Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2Q34093745
The E2F1-3 transcription factors are essential for cellular proliferation.Q34102966
Expression of transcription factor E2F1 induces quiescent cells to enter S phaseQ34354875
The function of the broad-complex during Drosophila melanogaster oogenesisQ34608127
The genetics of the E2F family of transcription factors: shared functions and unique rolesQ34646667
Delta signaling from the germ line controls the proliferation and differentiation of the somatic follicle cells during Drosophila oogenesisQ35078989
Functional antagonism between E2F family membersQ35080617
Mutations in Drosophila DP and E2F distinguish G1-S progression from an associated transcriptional programQ35187372
Cell cycle control of chorion gene amplificationQ35192801
ORC localization in Drosophila follicle cells and the effects of mutations in dE2F and dDP.Q35193528
The k43 gene, required for chorion gene amplification and diploid cell chromosome replication, encodes the Drosophila homolog of yeast origin recognition complex subunit 2Q36106897
Characterization of differentially expressed genes in purified Drosophila follicle cells: toward a general strategy for cell type-specific developmental analysisQ36358327
Drosophila chorion gene amplification requires an upstream region regulating s18 transcriptionQ36902366
Drosophila chorion genes: cracking the eggshell's secretsQ37350600
Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genesQ40016836
The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completionQ40926267
dE2F2, a novel E2F-family transcription factor in Drosophila melanogasterQ40999013
The Drosophila chiffon gene is required for chorion gene amplification, and is related to the yeast Dbf4 regulator of DNA replication and cell cycleQ41689031
Cell proliferation and DNA replication defects in a Drosophila MCM2 mutant.Q46218277
Drosophila E2f2 promotes the conversion from genomic DNA replication to gene amplification in ovarian follicle cellsQ47070690
RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in DrosophilaQ47071369
DNA replication control through interaction of E2F-RB and the origin recognition complexQ47071555
GAL4 enhancer traps expressed in the embryo, larval brain, imaginal discs, and ovary of drosophilaQ48674438
Selective activation of pre-replication complexes in vitro at specific sites in mammalian nuclei.Q52082030
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectE2F transcription factor 2 Dmel_CG1071Q29812234
P304page(s)2123-2134
P577publication date2003-03-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleTranscriptional repressor functions of Drosophila E2F1 and E2F2 cooperate to inhibit genomic DNA synthesis in ovarian follicle cells
P478volume23

Reverse relations

cites work (P2860)
Q50114305An alternatively spliced form affecting the Marked Box domain of Drosophila E2F1 is required for proper cell cycle regulation
Q33352965Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes
Q28508978Atypical E2F repressors and activators coordinate placental development
Q46870952Characterization of null and hypomorphic alleles of the Drosophila l(2)dtl/cdt2 gene: Larval lethality and male fertility.
Q44978894Chromatin regulates origin activity in Drosophila follicle cells
Q37249375Conserved functions of the pRB and E2F families
Q44310904Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 is essential for G1/S progression and cellular transformation
Q41733833Dampened activity of E2F1-DP and Myb-MuvB transcription factors in Drosophila endocycling cells
Q52675834Developmentally regulated histone modifications in Drosophila follicle cells: initiation of gene amplification is associated with histone H3 and H4 hyperacetylation and H1 phosphorylation.
Q36661084Dm-myb mutant lethality in Drosophila is dependent upon mip130: positive and negative regulation of DNA replication
Q36189905Drosophila Symplekin localizes dynamically to the histone locus body and tricellular junctions
Q52008779Ecdysone induces transcription and amplification in Sciara coprophila DNA puff II/9A.
Q98181942Evolutionarily Conserved Roles for Apontic in Induction and Subsequent Decline of Cyclin E Expression
Q36103645Genomic profiling and expression studies reveal both positive and negative activities for the Drosophila Myb MuvB/dREAM complex in proliferating cells
Q45119438Hypoxia induces major effects on cell cycle kinetics and protein expression in Drosophila melanogaster embryos.
Q37140463Identification of E2F target genes that are rate limiting for dE2F1-dependent cell proliferation
Q37694408Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex
Q42127933Initiation of Drosophila chorion gene amplification requires Claspin and mus101, whereas Claspin, but not mus101, plays a major role during elongation
Q35098584Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression.
Q37661454Isolation and characterization of the ecdysone receptor and its heterodimeric partner ultraspiracle through development in Sciara coprophila
Q28475455Mammalian MCM loading in late-G(1) coincides with Rb hyperphosphorylation and the transition to post-transcriptional control of progression into S-phase
Q24634248Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers
Q37478720Notch-dependent downregulation of the homeodomain gene cut is required for the mitotic cycle/endocycle switch and cell differentiation in Drosophila follicle cells
Q40550683RB reversibly inhibits DNA replication via two temporally distinct mechanisms
Q35583000Regulation of Cell Cycles in Drosophila Development: Intrinsic and Extrinsic Cues
Q36860411Regulation of the endocycle/gene amplification switch by Notch and ecdysone signaling
Q38205023Regulatory system for the G1-arrest during neuronal development in Drosophila
Q58696724Retinoblastoma Intrinsically Regulates Niche Cell Quiescence, Identity, and Niche Number in the Adult Drosophila Testis
Q90117016Rif1 Functions in a Tissue-Specific Manner To Control Replication Timing Through Its PP1-binding Motif
Q48177672Role of an atypical E2F transcription factor in the control of Arabidopsis cell growth and differentiation.
Q34390559S phase-coupled E2f1 destruction ensures homeostasis in proliferating tissues
Q33355967The N-terminal domain of the Drosophila retinoblastoma protein Rbf1 interacts with ORC and associates with chromatin in an E2F independent manner
Q36570170The microRNA miR-7 regulates Tramtrack69 in a developmental switch in Drosophila follicle cells
Q99234761Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity
Q48299228dUTPase expression correlates with cell division potential in Drosophila melanogaster.

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