The herpes simplex virus 1 IgG fc receptor blocks antibody-mediated complement activation and antibody-dependent cellular cytotoxicity in vivo

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The herpes simplex virus 1 IgG fc receptor blocks antibody-mediated complement activation and antibody-dependent cellular cytotoxicity in vivo is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.02509-10
P932PMC publication ID3067879
P698PubMed publication ID21228231

P50authorHarvey M. FriedmanQ89912954
Helen M. LazearQ37367303
P2093author name stringJohn M Lubinski
Sita Awasthi
Fushan Wang
P2860cites workCrystal structure of the HSV-1 Fc receptor bound to Fc reveals a mechanism for antibody bipolar bridgingQ21092776
An N-terminal domain of herpes simplex virus type Ig E is capable of forming stable complexes with gI.Q39605520
Virus attenuation after deletion of the cytomegalovirus Fc receptor gene is not due to antibody control.Q39642352
Identification and expression of human cytomegalovirus transcription units coding for two distinct Fcgamma receptor homologsQ39686594
Herpes simplex virus type 1 glycoprotein E mediates retrograde spread from epithelial cells to neuritesQ39874187
Antibody-induced and cytoskeleton-mediated redistribution and shedding of viral glycoproteins, expressed on pseudorabies virus-infected cellsQ39882095
Genetics of natural resistance to herpesvirus infections in miceQ39958787
Characterization of domains of herpes simplex virus type 1 glycoprotein E involved in Fc binding activity for immunoglobulin G aggregates.Q40040178
Receptor properties of two varicella-zoster virus glycoproteins, gpI and gpIV, homologous to herpes simplex virus gE and gIQ40065898
Specificity of Fc receptors induced by herpes simplex virus type 1: comparison of immunoglobulin G from different animal speciesQ40124901
The role of NK1.1+ cells in the protection against MHC class I+ HPV16-associated tumours.Q40458745
The herpes simplex virus-1 glycoprotein E (gE) mediates IgG binding and cell-to-cell spread through distinct gE domainsQ41105435
Mapping regions of herpes simplex virus type 1 glycoprotein I required for formation of the viral Fc receptor for monomeric IgG.Q41143799
Characterization of regions of herpes simplex virus type 1 glycoprotein E involved in binding the Fc domain of monomeric IgG and in forming a complex with glycoprotein I.Q41389075
Characterization of the interaction between the herpes simplex virus type I Fc receptor and immunoglobulin G.Q41611323
Direct evidence for antibody bipolar bridging on herpes simplex virus-infected cellsQ41900199
Fcγ Receptor-like Activity of Hepatitis C Virus Core ProteinQ42981184
Antibody-induced internalization of viral glycoproteins and gE-gI Fc receptor activity protect pseudorabies virus-infected monocytes from efficient complement-mediated lysisQ43530697
Viral interference with B7-1 costimulation: a new role for murine cytomegalovirus fc receptor-1.Q44062957
ADSORPTION OF SENSITIZED SHEEP ERYTHROCYTES TO HELA CELLS INFECTED WITH HERPES SIMPLEX VIRUS.Q44582827
Culturing primary and transformed neuronal cells for studying pseudorabies virus infectionQ45558330
Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infectionQ45733086
Virus Infection of Endothelial CellsQ45802359
Protection against herpetic ocular disease by immunotherapy with monoclonal antibodies to herpes simplex virus glycoproteinsQ45841413
Spontaneous ocular shedding of HSV-1 in latently infected rabbitsQ70081113
Diminution of experimental autoimmune uveoretinitis (EAU) in mice depleted of NK cellsQ78680362
Blocking antibody access to neutralizing domains on glycoproteins involved in entry as a novel mechanism of immune evasion by herpes simplex virus type 1 glycoproteins C and EQ24646778
Genetic Markers of IgG Influence the Outcome of Infection with Hepatitis C VirusQ27488362
Immunoglobulin concentrations in human tears in ocular diseasesQ33651328
Identification of a novel herpes simplex virus type 1-induced glycoprotein which complexes with gE and binds immunoglobulinQ33720617
In vivo immune evasion mediated by the herpes simplex virus type 1 immunoglobulin G Fc receptor.Q33784845
Herpes simplex virus type 1 glycoprotein gC mediates immune evasion in vivoQ33784923
The role of complement in B cell activation and tolerance.Q33799789
Herpes simplex virus type 1 glycoprotein E domains involved in virus spread and diseaseQ33808376
Human cytomegalovirus open reading frame TRL11/IRL11 encodes an immunoglobulin G Fc-binding proteinQ33849391
Immunoglobulin G(Fc)-binding receptors on virions of herpes simplex virus type 1 and transfer of these receptors to the cell surface by infectionQ33919647
Structural analysis of the capsid polypeptides of herpes simplex virus types 1 and 2Q33919700
Neuron-to-cell spread of pseudorabies virus in a compartmented neuronal culture systemQ33930401
The extracellular domain of herpes simplex virus gE is indispensable for efficient cell-to-cell spread: evidence for gE/gI receptorsQ33987514
Herpes simplex virus type 1 glycoprotein e is required for axonal localization of capsid, tegument, and membrane glycoproteinsQ34092761
Induction of immunoglobulin G Fc receptors by recombinant vaccinia viruses expressing glycoproteins E and I of herpes simplex virus type 1Q34185445
Herpes simplex virus type 1 evades the effects of antibody and complement in vivoQ34345831
Glycoproteins E and I facilitate neuron-to-neuron spread of herpes simplex virusQ35851060
The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60.Q36228791
A locus on mouse chromosome 6 that determines resistance to herpes simplex virus also influences reactivation, while an unlinked locus augments resistance of female mice.Q36540912
Herpes simplex virus glycoproteins E and I facilitate cell-to-cell spread in vivo and across junctions of cultured cellsQ36626714
Herpes simplex virus type 1 encodes two Fc receptors which have different binding characteristics for monomeric immunoglobulin G (IgG) and IgG complexesQ36807128
Herpes simplex virus type 1 Fc receptor protects infected cells from antibody-dependent cellular cytotoxicityQ36829124
A novel function of the herpes simplex virus type 1 Fc receptor: participation in bipolar bridging of antiviral immunoglobulin G.Q36831366
A replication-competent, neuronal spread-defective, live attenuated herpes simplex virus type 1 vaccineQ36845870
Herpes simplex virus immunoglobulin G Fc receptor activity depends on a complex of two viral glycoproteins, gE and gI.Q36866263
Role of antibody in primary and recurrent herpes simplex virus infectionQ36899596
Glycoprotein gE of herpes simplex virus type 1: effects of anti-gE on virion infectivity and on virus-induced fc-binding receptorsQ36936682
Similarities and differences in the Fc-binding glycoprotein (gE) of herpes simplex virus types 1 and 2 and tentative mapping of the viral gene for this glycoproteinQ36936703
Immunization strategies to block the herpes simplex virus type 1 immunoglobulin G Fc receptorQ36955074
Anterograde spread of herpes simplex virus type 1 requires glycoprotein E and glycoprotein I but not Us9.Q37333821
Membrane proteins specified by herpes simplex viruses. V. Identification of an Fc-binding glycoproteinQ37601627
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
cytotoxicityQ246181
P304page(s)3239-3249
P577publication date2011-01-12
P1433published inJournal of VirologyQ1251128
P1476titleThe herpes simplex virus 1 IgG fc receptor blocks antibody-mediated complement activation and antibody-dependent cellular cytotoxicity in vivo
P478volume85

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cites work (P2860)
Q90520696A trivalent gC2/gD2/gE2 vaccine for herpes simplex virus generates antibody responses that block immune evasion domains on gC2 better than natural infection
Q34549656An HSV-2 Trivalent Vaccine Is Immunogenic in Rhesus Macaques and Highly Efficacious in Guinea Pigs.
Q90107838Antibody-mediated complement activation in pathology and protection
Q34057952Blocking herpes simplex virus 2 glycoprotein E immune evasion as an approach to enhance efficacy of a trivalent subunit antigen vaccine for genital herpes
Q38257496CMV-encoded Fcγ receptors: modulators at the interface of innate and adaptive immunity
Q56880960CNS Infections
Q27320966Characterization of Antibody Bipolar Bridging Mediated by the Human Cytomegalovirus Fc Receptor gp68
Q33804431Complement Evasion Strategies of Viruses: An Overview
Q35414669Evasion of early antiviral responses by herpes simplex viruses
Q35804208HSV-1 Glycoproteins Are Delivered to Virus Assembly Sites Through Dynamin-Dependent Endocytosis
Q64078553Herpes Simplex Virus Evasion of Early Host Antiviral Responses
Q55397851Herpesviruses: Harmonious Pathogens but Relevant Cofactors in Other Diseases?
Q33618817Human cytomegalovirus Fcγ binding proteins gp34 and gp68 antagonize Fcγ receptors I, II and III
Q38116993Immunity to bovine herpesvirus 1: II. Adaptive immunity and vaccinology
Q35275146Immunization with a vaccine combining herpes simplex virus 2 (HSV-2) glycoprotein C (gC) and gD subunits improves the protection of dorsal root ganglia in mice and reduces the frequency of recurrent vaginal shedding of HSV-2 DNA in guinea pigs compa
Q39224323Immunoglobulin superfamily members encoded by viruses and their multiple roles in immune evasion.
Q38241377Improving immunogenicity and efficacy of vaccines for genital herpes containing herpes simplex virus glycoprotein D.
Q35192694Interaction and interdependent packaging of tegument protein UL11 and glycoprotein e of herpes simplex virus
Q38692329Maternal Antiviral Immunoglobulin Accumulates in Neural Tissue of Neonates To Prevent HSV Neurological Disease.
Q27347896Mathematical Modeling Predicts that Increased HSV-2 Shedding in HIV-1 Infected Persons Is Due to Poor Immunologic Control in Ganglia and Genital Mucosa
Q38824720Novel Evasion Mechanisms of the Classical Complement Pathway.
Q60044040Oncolytic herpes simplex virus and immunotherapy
Q38920459Oncolytic herpes simplex virus interactions with the host immune system
Q21284969Systemic delivery of oncolytic viruses: hopes and hurdles
Q38650844The Neonatal Fc Receptor and Complement Fixation Facilitate Prophylactic Vaccine-Mediated Humoral Protection against Viral Infection in the Ocular Mucosa.
Q90290839The Roles of Host and Viral Antibody Fc Receptors in Herpes Simplex Virus (HSV) and Human Cytomegalovirus (HCMV) Infections and Immunity
Q27330259The herpes virus Fc receptor gE-gI mediates antibody bipolar bridging to clear viral antigens from the cell surface
Q42256835Treg depletion attenuates the severity of skin disease from ganglionic spread after HSV-2 flank infection
Q90437526Trivalent glycoprotein subunit vaccine prevents neonatal herpes simplex virus mortality and morbidity
Q55406946Vaccine-induced antibodies to herpes simplex virus glycoprotein D epitopes involved in virus entry and cell-to-cell spread correlate with protection against genital disease in guinea pigs.
Q91766368Vaccines to prevent genital herpes

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