scholarly article | Q13442814 |
P50 | author | Peter D. Mace | Q42423701 |
Bernhard C Lechtenberg | Q81790787 | ||
P2093 | author name string | Elena B Pasquale | |
Stefan J Riedl | |||
Philip E Dawson | |||
Ilaria Lamberto | |||
Erika J Olson | |||
P2860 | cites work | MolProbity: all-atom structure validation for macromolecular crystallography | Q24649111 |
EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice | Q27320846 | ||
Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor | Q27651657 | ||
Structural Plasticity of Eph Receptor A4 Facilitates Cross-Class Ephrin Signaling | Q27657815 | ||
Structural Characterization of the EphA4-Ephrin-B2 Complex Reveals New Features Enabling Eph-Ephrin Binding Promiscuity | Q27658020 | ||
Structurally encoded intraclass differences in EphA clusters drive distinct cell responses | Q27678839 | ||
Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5 | Q27679723 | ||
Overview of the CCP4 suite and current developments | Q27860782 | ||
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction | Q27860958 | ||
iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM | Q27861099 | ||
Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport | Q28251532 | ||
A quantitative analysis of kinase inhibitor selectivity | Q28264038 | ||
The future of peptide-based drugs | Q28281702 | ||
Regeneration-enhancing effects of EphA4 blocking peptide following corticospinal tract injury in adult rat spinal cord | Q28584025 | ||
EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomers | Q29347252 | ||
Anatomy of hot spots in protein interfaces | Q29616238 | ||
Eph-ephrin bidirectional signaling in physiology and disease | Q29617975 | ||
Eph receptor signalling casts a wide net on cell behaviour | Q29619988 | ||
Molecular features of the transition from prostatic intraepithelial neoplasia (PIN) to prostate cancer: genome-wide gene-expression profiles of prostate cancers and PINs | Q31108703 | ||
Discovery and characterization of a novel cyclic peptide that effectively inhibits ephrin binding to the EphA4 receptor and displays anti-angiogenesis activity | Q31144324 | ||
EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth | Q33257109 | ||
Blockade of EphA4 signaling ameliorates hippocampal synaptic dysfunctions in mouse models of Alzheimer's disease | Q33919522 | ||
Attenuation of scratch-induced reactive astrogliosis by novel EphA4 kinase inhibitors. | Q33953835 | ||
Eph receptors and ephrins in cancer: bidirectional signalling and beyond | Q34021365 | ||
Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome. | Q34026097 | ||
Protein dynamics at Eph receptor-ligand interfaces as revealed by crystallography, NMR and MD simulations | Q34141080 | ||
Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations | Q34170551 | ||
HTS by NMR of combinatorial libraries: a fragment-based approach to ligand discovery | Q34564346 | ||
Global evaluation of Eph receptors and ephrins in lung adenocarcinomas identifies EphA4 as an inhibitor of cell migration and invasion | Q36223133 | ||
Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor | Q36914295 | ||
Acute delivery of EphA4-Fc improves functional recovery after contusive spinal cord injury in rats | Q36947648 | ||
RNAi screen for rapid therapeutic target identification in leukemia patients | Q37187716 | ||
Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport | Q37579588 | ||
Targeting Eph receptors with peptides and small molecules: progress and challenges | Q37951723 | ||
Eph receptors at synapses: implications in neurodegenerative diseases. | Q37961534 | ||
Therapeutic perspectives of Eph-ephrin system modulation. | Q38167588 | ||
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans | Q38322311 | ||
MicroRNA-10a is involved in the metastatic process by regulating Eph tyrosine kinase receptor A4-mediated epithelial-mesenchymal transition and adhesion in hepatoma cells | Q39274635 | ||
Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases | Q39567597 | ||
Overexpression of the receptor tyrosine kinase EphA4 in human gastric cancers. | Q39932205 | ||
EphA4 promotes cell proliferation and migration through a novel EphA4-FGFR1 signaling pathway in the human glioma U251 cell line | Q39940130 | ||
Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors | Q41875227 | ||
EphA4 signaling in juveniles establishes topographic specificity of structural plasticity in the hippocampus | Q43133200 | ||
Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling | Q44259200 | ||
Modifying expression of EphA4 and its downstream targets improves functional recovery after stroke | Q44310626 | ||
Targeting the EphA4 receptor in the nervous system with biologically active peptides | Q44707568 | ||
EphA and ephrin-A proteins regulate integrin-mediated T lymphocyte interactions | Q46915994 | ||
P433 | issue | 12 | |
P304 | page(s) | 2787-2795 | |
P577 | publication date | 2014-10-14 | |
P1433 | published in | ACS Chemical Biology | Q165583 |
P1476 | title | Development and structural analysis of a nanomolar cyclic peptide antagonist for the EphA4 receptor | |
P478 | volume | 9 |
Q90250053 | Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling |
Q60933281 | EphA4-ADAM10 Interplay Patterns the Cochlear Sensory Epithelium through Local Disruption of Adherens Junctions |
Q49709391 | EphB4: A promising target for upper aerodigestive malignancies |
Q35634594 | High-Throughput Screening by Nuclear Magnetic Resonance (HTS by NMR) for the Identification of PPIs Antagonists |
Q33882055 | Identification and characterization of Nanobodies targeting the EphA4 receptor. |
Q41063994 | Modifications of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor To Achieve High Plasma Stability |
Q55367685 | Modulatory Effects of a Novel Cyclized Peptide in Reducing the Expression of Markers Linked to Alzheimer's Disease. |
Q46499375 | Potent and Selective EphA4 Agonists for the Treatment of ALS. |
Q46167371 | SORLA attenuates EphA4 signaling and amyloid β-induced neurodegeneration |
Q30398451 | Targeting kinase signaling pathways with constrained peptide scaffolds |
Q26799461 | Targeting the Eph System with Peptides and Peptide Conjugates |
Q51503040 | The Role of EphA4 Signaling in Radiation-Induced EMT-Like Phenotype in Colorectal Cancer Cells. |
Q57812327 | Therapeutic potential of targeting the Eph/ephrin signaling complex |
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