Modifying expression of EphA4 and its downstream targets improves functional recovery after stroke

scientific article

Modifying expression of EphA4 and its downstream targets improves functional recovery after stroke is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/HMG/DDT073
P8608Fatcat IDrelease_57py4kajpbh5xbaw3jn4bvijze
P698PubMed publication ID23418304
P5875ResearchGate publication ID235650438

P50authorWim RobberechtQ30111701
P2093author name stringRobin Lemmens
Vincent N Thijs
Tom Jaspers
P2860cites workExecutive Summary: Heart Disease and Stroke Statistics--2012 Update: A Report From the American Heart AssociationQ22241920
Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesisQ24608892
Axonal regeneration and lack of astrocytic gliosis in EphA4-deficient miceQ28592877
Fasudil improves survival and promotes skeletal muscle development in a mouse model of spinal muscular atrophyQ30511954
Clinical trials with neuroprotective drugs in acute ischaemic stroke: are we doing the right thing?Q30583493
Photochemically induced, graded cerebral infarction in the mouse by laser irradiation evolution of brain edemaQ33213830
Treatment time-specific number needed to treat estimates for tissue plasminogen activator therapy in acute stroke based on shifts over the entire range of the modified Rankin Scale.Q33897269
Ephrin-B3 is a myelin-based inhibitor of neurite outgrowthQ33897550
Promoting axonal rewiring to improve outcome after strokeQ34020263
An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke.Q34688738
A new penumbra: transitioning from injury into repair after strokeQ34777115
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicityQ35990227
A role for ephrin-A5 in axonal sprouting, recovery, and activity-dependent plasticity after strokeQ36170813
Neuronal clues to vascular guidanceQ36331960
Cellular and molecular mechanisms of neural repair after stroke: making waves.Q36457986
Axonal growth therapeutics: regeneration or sprouting or plasticity?Q37131897
Bidirectional modulation of synaptic functions by Eph/ephrin signaling.Q37333581
Reducing prehospital delay in acute strokeQ37577325
Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transportQ37579588
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humansQ38322311
Neuroprotective properties of a protein kinase inhibitor against ischaemia-induced neuronal damage in rats and gerbilsQ42593259
Fasudil, a Rho kinase inhibitor, drives mobilization of adult neural stem cells after hypoxia/reoxygenation injury in miceQ43242334
Non-invasive induction of focal cerebral ischemia in mice by photothrombosis of cortical microvessels: characterization of inflammatory responsesQ44041786
Identification of neuroprotective properties of anti-MAG antibody: a novel approach for the treatment of stroke?Q45242550
Rho kinase inhibitor Fasudil induces neuroprotection and neurogenesis partially through astrocyte-derived G-CSF.Q46009054
Defining brain wiring patterns and mechanisms through gene trapping in mice.Q46112482
Growth-associated gene expression after stroke: evidence for a growth-promoting region in peri-infarct cortexQ46471068
Effects of fasudil in acute ischemic stroke: results of a prospective placebo-controlled double-blind trialQ46591653
Nogo receptor antagonism promotes stroke recovery by enhancing axonal plasticity.Q47230824
t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes.Q48701544
Rho-kinase inactivation prolongs survival of an intermediate SMA mouse model.Q52598269
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)2214-2220
P577publication date2013-02-14
P1433published inHuman Molecular GeneticsQ2720965
P1476titleModifying expression of EphA4 and its downstream targets improves functional recovery after stroke
P478volume22

Reverse relations

cites work (P2860)
Q28392297ALS as a distal axonopathy: molecular mechanisms affecting neuromuscular junction stability in the presymptomatic stages of the disease
Q41667151Combination of early constraint-induced movement therapy and fasudil enhances motor recovery after ischemic stroke in rats
Q47975657Critical role of EphA4 in early brain injury after subarachnoid hemorrhage in rat.
Q90647742Decreased signalling of EphA4 improves functional performance and motor neuron survival in the SOD1G93A ALS mouse model
Q34756811Development and structural analysis of a nanomolar cyclic peptide antagonist for the EphA4 receptor
Q37694154Effect of task-specific training on Eph/ephrin expression after stroke
Q91783160Environmental enrichment during the chronic phase after experimental stroke promotes functional recovery without synergistic effects of EphA4 targeted therapy
Q38257853Eph receptors and ephrins: therapeutic opportunities
Q37528939Genetic ablation of IP3 receptor 2 increases cytokines and decreases survival of SOD1G93A mice
Q47870925How does language change after an intensive treatment on imitation?
Q33882055Identification and characterization of Nanobodies targeting the EphA4 receptor.
Q99710984Inducible EphA4 knockout causes motor deficits in young mice and is not protective in the SOD1G93A mouse model of ALS
Q46931764Inhibition of Rho-kinase protects cerebral barrier from ischaemia-evoked injury through modulations of endothelial cell oxidative stress and tight junctions.
Q41967459Is integration and survival of newborn neurons the bottleneck for effective neural repair by endogenous neural precursor cells?
Q91706732Lowering EphA4 Does Not Ameliorate Disease in a Mouse Model for Severe Spinal Muscular Atrophy
Q28075887Modulating Astrocyte Transition after Stroke to Promote Brain Rescue and Functional Recovery: Emerging Targets Include Rho Kinase
Q38732238Molecular, cellular and functional events in axonal sprouting after stroke.
Q58557363Neuronal EphA4 Regulates OGD/R-Induced Apoptosis by Promoting Alternative Activation of Microglia
Q38635333Neuroplastic Changes Induced by Cognitive Rehabilitation in Traumatic Brain Injury: A Review
Q38122368Noninvasive strategies to promote functional recovery after stroke.
Q90426015Reducing EphA4 before disease onset does not affect survival in a mouse model of Amyotrophic Lateral Sclerosis
Q37450106Rho kinases in cardiovascular physiology and pathophysiology: the effect of fasudil
Q36673898The Specific Requirements of Neural Repair Trials for Stroke.