scholarly article | Q13442814 |
P50 | author | Sara Ortega Atienza | Q60058080 |
P2093 | author name string | Michal W Luczak | |
Anatoly Zhitkovich | |||
Zachary DeLoughery | |||
P2860 | cites work | Ascorbate is the principal reductant of chromium (VI) in rat liver and kidney ultrafiltrates | Q67975160 |
Reduction of hexavalent chromium by ascorbic acid and glutathione with special reference to the rat lung | Q68857566 | ||
Reaction of chromium(VI) with ascorbate produces chromium(V), chromium(IV), and carbon-based radicals | Q72492310 | ||
Cellular vitamin C increases chromate toxicity via a death program requiring mismatch repair but not p53 | Q79775621 | ||
Hexavalent chromium and lung cancer in the chromate industry: a quantitative risk assessment | Q23920347 | ||
A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response | Q24299489 | ||
The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα | Q24339204 | ||
Postreplicative mismatch repair | Q27690911 | ||
ATM phosphorylates histone H2AX in response to DNA double-strand breaks | Q28188651 | ||
Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium | Q28255368 | ||
Regulation of DNA double-strand break repair pathway choice | Q28262730 | ||
Genomic instability in mice lacking histone H2AX | Q28589826 | ||
Double strand break repair functions of histone H2AX | Q28661754 | ||
Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair. | Q30524137 | ||
gammaH2AX foci form preferentially in euchromatin after ionising-radiation. | Q33303665 | ||
Monitoring Cr intermediates and reactive oxygen species with fluorescent probes during chromate reduction | Q33637092 | ||
Mechanism of DNA-protein cross-linking by chromium | Q33653854 | ||
Mismatch repair proteins are activators of toxic responses to chromium-DNA damage | Q33758325 | ||
Double-strand break repair: 53BP1 comes into focus | Q34391068 | ||
DNA double-strand break repair: all's well that ends well | Q34555274 | ||
WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts | Q35580739 | ||
Vitamin C: basic metabolism and its function as an index of oxidative stress | Q35743610 | ||
Undetectable role of oxidative DNA damage in cell cycle, cytotoxic and clastogenic effects of Cr(VI) in human lung cells with restored ascorbate levels | Q36055967 | ||
Mouse centric and pericentric satellite repeats form distinct functional heterochromatin | Q36322196 | ||
Biochemical mechanisms of chromosomal translocations resulting from DNA double-strand breaks | Q36528173 | ||
DNA damage-induced cell death by apoptosis. | Q36561337 | ||
The Werner syndrome protein functions in repair of Cr(VI)-induced replication-associated DNA damage | Q37256608 | ||
More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance | Q37942059 | ||
Histone modifications for human epigenome analysis | Q38112246 | ||
Systematic identification of functional residues in mammalian histone H2AX | Q39251706 | ||
Rapid DNA double-strand breaks resulting from processing of Cr-DNA cross-links by both MutS dimers | Q39464747 | ||
Causes of DNA single-strand breaks during reduction of chromate by glutathione in vitro and in cells | Q40276804 | ||
Human nucleotide excision repair efficiently removes chromium-DNA phosphate adducts and protects cells against chromate toxicity | Q40566148 | ||
Chromium inhibits transcription from polycyclic aromatic hydrocarbon-inducible promoters by blocking the release of histone deacetylase and preventing the binding of p300 to chromatin. | Q40615478 | ||
Differential effects of chromium(VI) on constitutive and inducible gene expression in chick embryo liver in vivo and correlation with chromium(VI)-induced DNA damage | Q42496016 | ||
Ascorbate acts as a highly potent inducer of chromate mutagenesis and clastogenesis: linkage to DNA breaks in G2 phase by mismatch repair | Q42949332 | ||
Carcinogenic chromium(VI) induces cross-linking of vitamin C to DNA in vitro and in human lung A549 cells | Q43894612 | ||
Generation of S phase-dependent DNA double-strand breaks by Cr(VI) exposure: involvement of ATM in Cr(VI) induction of gamma-H2AX. | Q45000379 | ||
Glutathione and free amino acids form stable complexes with DNA following exposure of intact mammalian cells to chromate. | Q53464761 | ||
P433 | issue | 1 | |
P921 | main subject | phosphorylation | Q242736 |
euchromatin | Q910324 | ||
protein ubiquitination | Q3547638 | ||
P304 | page(s) | 54-63 | |
P577 | publication date | 2014-10-06 | |
P1433 | published in | Toxicological Sciences | Q2446966 |
P1476 | title | DNA double-strand breaks by Cr(VI) are targeted to euchromatin and cause ATR-dependent phosphorylation of histone H2AX and its ubiquitination | |
P478 | volume | 143 |
Q33677593 | 20S immunoproteasomes remove formaldehyde-damaged cytoplasmic proteins suppressing caspase-independent cell death |
Q36456197 | Different ATM Signaling in Response to Chromium(VI) Metabolism via Ascorbate and Nonascorbate Reduction: Implications for in Vitro Models and Toxicogenomics |
Q33569518 | Environmental exposure to arsenic and chromium in an industrial area |
Q28395858 | Gene 33/Mig6 inhibits hexavalent chromium-induced DNA damage and cell transformation in human lung epithelial cells |
Q64389270 | Monoubiquitinated γ-H2AX: Abundant product and specific biomarker for non-apoptotic DNA double-strand breaks |
Q38701982 | Nickel-induced HIF-1α promotes growth arrest and senescence in normal human cells but lacks toxic effects in transformed cells |
Q47134376 | Residual γH2AX foci induced by low dose x-ray radiation in bone marrow mesenchymal stem cells do not cause accelerated senescence in the progeny of irradiated cells |
Q58700484 | Tdp1 processes chromate-induced single-strand DNA breaks that collapse replication forks |
Q58606129 | Toxicological Antagonism among Welding Fume Metals: Inactivation of Soluble Cr(VI) by Iron |
Q41705208 | Variation in Extracellular Detoxification Is a Link to Different Carcinogenicity among Chromates in Rodent and Human Lungs |
Q64387425 | Vitamin C increases DNA breaks and suppresses DNA damage-independent activation of ATM by bleomycin |
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