scholarly article | Q13442814 |
P50 | author | Zbyszek Darzynkiewicz | Q33103772 |
Hong Zhao | Q77639007 | ||
P2093 | author name string | Soyoung Park | |
Dazhong Xu | |||
Cen Li | |||
P2860 | cites work | Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent stre | Q22253460 |
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Nitric oxide-mediated Bcl-2 stabilization potentiates malignant transformation of human lung epithelial cells | Q23918831 | ||
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The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity | Q24314999 | ||
EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment | Q24338426 | ||
Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications | Q24608343 | ||
Genomic and proteomic profiling of responses to toxic metals in human lung cells | Q24814797 | ||
Evidence that MIG-6 is a tumor-suppressor gene | Q28250282 | ||
Genomic instability--an evolving hallmark of cancer | Q28274009 | ||
Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function | Q28294466 | ||
The DNA-dependent protein kinase | Q28373950 | ||
Constitutive activation of epidermal growth factor receptor promotes tumorigenesis of Cr(VI)-transformed cells through decreased reactive oxygen species and apoptosis resistance development | Q28386290 | ||
Reactive oxygen species mediate Cr(VI)-induced carcinogenesis through PI3K/AKT-dependent activation of GSK-3β/β-catenin signaling | Q28387227 | ||
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NADPH oxidase activation is required in reactive oxygen species generation and cell transformation induced by hexavalent chromium | Q28392194 | ||
Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation | Q28590384 | ||
Long-term exposure to low-concentrations of Cr(VI) induce DNA damage and disrupt the transcriptional response to benzo[a]pyrene | Q28658104 | ||
Exposure to nickel, chromium, or cadmium causes distinct changes in the gene expression patterns of a rat liver derived cell line | Q28742638 | ||
GammaH2AX and cancer | Q29614974 | ||
Lung cancer | Q29615473 | ||
Regulating the p53 pathway: in vitro hypotheses, in vivo veritas | Q29615658 | ||
microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma | Q30407637 | ||
Cytometric analysis of DNA damage: phosphorylation of histone H2AX as a marker of DNA double-strand breaks (DSBs). | Q33432971 | ||
Epigenetics in metal carcinogenesis: nickel, arsenic, chromium and cadmium | Q33835721 | ||
Comparison of gene expression profiles in chromate transformed BEAS-2B cells | Q33855548 | ||
Mig-6 controls EGFR trafficking and suppresses gliomagenesis | Q33859568 | ||
ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells. | Q34049864 | ||
EGFR modulates DNA synthesis and repair through Tyr phosphorylation of histone H4. | Q34109344 | ||
Mechanism of action of camptothecin | Q34149055 | ||
DNA double-strand breaks by Cr(VI) are targeted to euchromatin and cause ATR-dependent phosphorylation of histone H2AX and its ubiquitination. | Q34760238 | ||
Monoubiquitination of H2AX protein regulates DNA damage response signaling | Q35150282 | ||
Environmental epigenetics in metal exposure | Q35592179 | ||
Complexities of chromium carcinogenesis: role of cellular response, repair and recovery mechanisms | Q35595461 | ||
Toxicity and carcinogenicity of chromium compounds in humans | Q36493576 | ||
Mig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasis | Q36852720 | ||
Regulation of DNA repair throughout the cell cycle | Q37088926 | ||
Carcinogenicity of hexavalent chromium. | Q37357620 | ||
Proteasome inhibitors: an expanding army attacking a unique target | Q37979388 | ||
Assessment of the mode of action for hexavalent chromium-induced lung cancer following inhalation exposures | Q38244952 | ||
The TGFβ-miR200-MIG6 pathway orchestrates the EMT-associated kinase switch that induces resistance to EGFR inhibitors | Q38994746 | ||
Differential responses to genotoxic agents between induced pluripotent stem cells and tumor cell lines | Q39053392 | ||
Regulation of EGFR trafficking and cell signaling by Sprouty2 and MIG6 in lung cancer cells | Q39123581 | ||
The mitogen-inducible gene-6 is involved in regulation of cellular senescence in normal diploid fibroblasts | Q39142664 | ||
Rapid DNA double-strand breaks resulting from processing of Cr-DNA cross-links by both MutS dimers | Q39464747 | ||
Downregulation of Mig-6 in nonsmall-cell lung cancer is associated with EGFR signaling | Q39510460 | ||
Human bronchial epithelial cells malignantly transformed by hexavalent chromium exhibit an aneuploid phenotype but no microsatellite instability. | Q39823708 | ||
Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth | Q40358363 | ||
Phosphorylation of histone H2AX at M phase in human cells without DNA damage response | Q40375352 | ||
Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase | Q40401323 | ||
A two-tiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation. | Q40464017 | ||
Gene 33/RALT is induced by hypoxia in cardiomyocytes, where it promotes cell death by suppressing phosphatidylinositol 3-kinase and extracellular signal-regulated kinase survival signaling. | Q41491151 | ||
ATM activation and histone H2AX phosphorylation as indicators of DNA damage by DNA topoisomerase I inhibitor topotecan and during apoptosis | Q46903679 | ||
Lung cancer among workers in chromium chemical production | Q47667127 | ||
Cytokinesis-block micronucleus cytome assay. | Q53548886 | ||
Genotoxic ability of cadmium, chromium and nickel salts studied by kinetochore staining in the cytokinesis-blocked micronucleus assay | Q73849817 | ||
Genomewide loss of heterozygosity and its clinical associations in non small cell lung cancer | Q81757968 | ||
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | hexavalent chromium | Q2660666 |
DNA damage | Q5205747 | ||
P304 | page(s) | 8916-30 | |
P577 | publication date | 2016-02-23 | |
P1433 | published in | Oncotarget | Q1573155 |
P1476 | title | Gene 33/Mig6 inhibits hexavalent chromium-induced DNA damage and cell transformation in human lung epithelial cells | |
P478 | volume | 7 |
Q37633880 | Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species. |
Q47888526 | Mutual regulation between Polo-like kinase 3 and SIAH2 E3 ubiquitin ligase defines a regulatory network that fine-tunes the cellular response to hypoxia and nickel |
Q38607684 | Nuclear Gene 33/Mig6 Regulates the DNA Damage Response through an ATM-dependent Mechanism |
Q38688209 | Single-cell RNA sequencing reveals an altered gene expression pattern as a result of CRISPR/cas9-mediated deletion of Gene 33/Mig6 and chronic exposure to hexavalent chromium in human lung epithelial cells |
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