scholarly article | Q13442814 |
P2093 | author name string | Annette M Marleau | |
Nora E Sarvetnick | |||
P2860 | cites work | Reduction in insulitis following administration of IFN-gamma and TNF-alpha in the NOD mouse | Q67996898 |
IFN-gamma and tumor necrosis factor-alpha. Cytotoxicity to murine islets of Langerhans | Q70405590 | ||
Following a diabetogenic T cell from genesis through pathogenesis | Q70488192 | ||
Crosses of NOD mice with the related NON strain. A polygenic model for IDDM | Q71736914 | ||
Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice | Q73299448 | ||
Systemic Production of Interferon-Gamma Inducing Factor (IGIF) Versus Local IFN-γ Expression Involved in the Development of Th1 Insulitis in NOD Mice | Q73501283 | ||
A mechanism underlying synergy between IL-12 and IFN-gamma-inducing factor in enhanced production of IFN-gamma | Q73648057 | ||
An IFN-gamma-dependent pathway controls stimulation of memory phenotype CD8+ T cell turnover in vivo by IL-12, IL-18, and IFN-gamma | Q73850507 | ||
IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-gamma by NK cells | Q74279845 | ||
IFN-gamma affects homing of diabetogenic T cells | Q77198737 | ||
IL-12 up-regulates IL-18 receptor expression on T cells, Th1 cells, and B cells: synergism with IL-18 for IFN-gamma production | Q77367658 | ||
IL-18 inhibits diabetes development in nonobese diabetic mice by counterregulation of Th1-dependent destructive insulitis | Q78025358 | ||
Pancreas-infiltrating Th1 cells and diabetes develop in IL-12-deficient nonobese diabetic mice | Q78145332 | ||
Gamma interferon paradoxically inhibits the development of diabetes in the NOD mouse | Q78482270 | ||
Th1 and Th2 pancreatic inflammation differentially affects homing of islet-reactive CD4 cells in nonobese diabetic mice | Q78946090 | ||
Systemic administration of IL-18 promotes diabetes development in young nonobese diabetic mice | Q79317471 | ||
Serum interleukin-18 levels are increased and closely associated with various soluble adhesion molecule levels in type 1 diabetic patients | Q79455847 | ||
Naive CD4+ T lymphocytes circulate through lymphoid organs to interact with endogenous antigens and upregulate their function | Q83375925 | ||
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance | Q83864443 | ||
IL-18 produced by thymic epithelial cells induces development of dendritic cells with CD11b in the fetal thymus | Q83986359 | ||
Lymphopenia-induced spontaneous T-cell proliferation as a cofactor for autoimmune disease development | Q84136013 | ||
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions | Q28146072 | ||
Cloning of a new cytokine that induces IFN-gamma production by T cells | Q28283928 | ||
An IFN-gamma-IL-18 signaling loop accelerates memory CD8+ T cell proliferation | Q33342847 | ||
The inflammasomes. | Q33521252 | ||
IL-12-induced IFN-gamma is dependent on caspase-1 processing of the IL-18 precursor | Q33853915 | ||
Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. | Q33977505 | ||
Responses of IL-18- and IL-18 receptor-deficient pancreatic islets with convergence of positive and negative signals for the IL-18 receptor | Q35130769 | ||
Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes | Q35634096 | ||
Regulation of interleukin (IL)-18 receptor alpha chain expression on CD4(+) T cells during T helper (Th)1/Th2 differentiation. Critical downregulatory role of IL-4 | Q36369407 | ||
Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice | Q36380895 | ||
Homeostasis of memory T cells | Q36528980 | ||
Interleukin-18 and the pathogenesis of inflammatory diseases | Q36750958 | ||
Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire. | Q37095109 | ||
Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice | Q37111353 | ||
Gene expression, synthesis, and secretion of interleukin 18 and interleukin 1beta are differentially regulated in human blood mononuclear cells and mouse spleen cells | Q37179132 | ||
Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice. | Q37193763 | ||
Active stage of autoimmune diabetes is associated with the expression of a novel cytokine, IGIF, which is located near Idd2. | Q37363100 | ||
Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells. | Q37370178 | ||
Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response | Q37376774 | ||
IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death | Q38303234 | ||
Bystander activation of CD8+ T cells contributes to the rapid production of IFN-gamma in response to bacterial pathogens | Q39171860 | ||
Identification of IL-18 and Th17 cells in salivary glands of patients with Sjögren's syndrome, and amplification of IL-17-mediated secretion of inflammatory cytokines from salivary gland cells by IL-18. | Q39953212 | ||
Functional IL-18 Is produced by primary pancreatic mouse islets and NIT-1 beta cells and participates in the progression towards destructive insulitis | Q40732633 | ||
Turnover of naive- and memory-phenotype T cells | Q41475935 | ||
"Bystander polarization" of CD4+ T cells: activation with high-dose IL-2 renders naive T cells responsive to IL-12 and/or IL-18 in the absence of TCR ligation | Q44481494 | ||
Essential pathogenic role of endogenous IL-18 in murine diabetes induced by multiple low doses of streptozotocin. Prevention of hyperglycemia and insulitis by a recombinant IL-18-binding protein: Fc construct | Q44528111 | ||
Caspase-1 is not required for type 1 diabetes in the NOD mouse | Q44704977 | ||
Activation of virus-specific CD8+ T cells by lipopolysaccharide-induced IL-12 and IL-18. | Q45548915 | ||
Increased atherosclerotic lesions and Th17 in interleukin-18 deficient apolipoprotein E-knockout mice fed high-fat diet | Q46129274 | ||
Genetic absence of gamma-interferon delays but does not prevent diabetes in NOD mice | Q46314387 | ||
IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12-induced IFN-gamma | Q47897970 | ||
IL-18 binding protein fusion construct delays the development of diabetes in adoptive transfer and cyclophosphamide-induced diabetes in NOD mouse | Q48550682 | ||
Division-linked differentiation can account for CD8+ T-cell phenotype in vivo. | Q51857017 | ||
Synergistic effect of IL-2, IL-12, and IL-18 on thymocyte apoptosis and Th1/Th2 cytokine expression. | Q52973794 | ||
P433 | issue | 3-4 | |
P304 | page(s) | 263-277 | |
P577 | publication date | 2011-03-16 | |
P1433 | published in | Journal of Autoimmunity | Q15716783 |
P1476 | title | IL-18 is required for self-reactive T cell expansion in NOD mice | |
P478 | volume | 36 |
Q38124723 | IL-18 in inflammatory and autoimmune disease |
Q35044541 | Increased expression of IL-18 in the serum and islets of type 1 diabetics |
Q92711317 | Interleukin-18 Expression Increases in the Aorta and Plasma of Patients with Acute Aortic Dissection |
Q36056835 | NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets. |
Q39302816 | The immunobiology of apotransferrin in type 1 diabetes |
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