Suppressed retinal degeneration in aged wild type and APPswe/PS1ΔE9 mice by bone marrow transplantation

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Suppressed retinal degeneration in aged wild type and APPswe/PS1ΔE9 mice by bone marrow transplantation is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...864246Y
P356DOI10.1371/JOURNAL.PONE.0064246
P932PMC publication ID3672108
P698PubMed publication ID23750207
P5875ResearchGate publication ID237093757

P2093author name stringYue Yang
C Dirk Keene
Bryan Richard Shalloway
Christine Shiao
Jake Frederick Hemingway
Nikolas L Jorstad
Rubens Chang
P2860cites workCaspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-betaQ22011091
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeuticsQ27860914
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxinsQ29547593
Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse modelQ29617937
Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's diseaseQ30725675
Reduction of optic nerve fibers in patients with Alzheimer disease identified by laser imagingQ33264775
Effects of age on optical coherence tomography measurements of healthy retinal nerve fiber layer, macula, and optic nerve headQ33431734
High-dose radiation with bone marrow transfer prevents neurodegeneration in an inherited glaucomaQ33934185
Suppressed accumulation of cerebral amyloid {beta} peptides in aged transgenic Alzheimer's disease mice by transplantation with wild-type or prostaglandin E2 receptor subtype 2-null bone marrowQ33947287
The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degenerationQ34154466
Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient miceQ34236802
Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse modelQ34349078
Age-related losses of retinal ganglion cells and axonsQ46551164
Characteristics of bone marrow-derived microglia in the normal and injured retinaQ46589820
Amyloid beta peptide causes chronic glial cell activation and neuro-degeneration after intravitreal injectionQ46692900
Long-term engraftment of systemically transplanted, gene-modified bone marrow-derived cells in the adult mouse retinaQ46786418
Retinal tau pathology in human glaucomasQ46792086
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditionsQ46891042
Chronic dietary alpha-lipoic acid reduces deficits in hippocampal memory of aged Tg2576 miceQ46920845
Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's diseaseQ46942969
Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microgliaQ47764327
Abnormal retinal thickness in patients with mild cognitive impairment and Alzheimer's diseaseQ48148917
Radiation-induced apoptosis in retinal progenitor cells is p53-dependent with caspase-independent DNA fragmentationQ48209388
AbetaPP induces cdk5-dependent tau hyperphosphorylation in transgenic mice Tg2576.Q48439872
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteinsQ48601563
Co-expression of multiple transgenes in mouse CNS: a comparison of strategiesQ48889458
Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to beta-amyloid deposition in APP/PS1 double transgenic Alzheimer mice.Q49149683
Apoptotic cell death and regeneration in the newborn retina after irradiation prior to bone marrow transplantation.Q50674410
Turnover of resident retinal microglia in the normal adult mouse.Q50675223
Retinal ganglion cells in Alzheimer's disease and aging.Q51053350
Pathological correlates of dementia in a longitudinal, population-based sample of aging.Q51905667
Relationship between cognitive impairment and retinal morphological and visual functional abnormalities in Alzheimer disease.Q51920606
Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules.Q52200995
Neuropathology of Alzheimer's disease.Q53137703
Alzheimer's disease, optic neuropathy, and selective ganglion cell damage.Q53185811
Visual loss and getting lost in Alzheimer's disease.Q53227022
The effect of age on the nerve fiber population of the human optic nerveQ71380247
Immunoreactivity against tau, amyloid precursor protein, and beta-amyloid in the human retinaQ72410730
Inflammatory processes in Alzheimer's diseaseQ79557863
Amyloid and tau proteins in cortical brain biopsy and Alzheimer's diseaseQ82060363
Low-dose-rate, low-dose irradiation delays neurodegeneration in a model of retinitis pigmentosaQ82460154
Microglial chemotaxis, activation, and phagocytosis of amyloid beta-peptide as linked phenomena in Alzheimer's diseaseQ34386095
Early reduction of microglia activation by irradiation in a model of chronic glaucomaQ34405368
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenesQ34452028
Alzheimer disease therapy: can the amyloid cascade be halted?Q34828328
Microglia and inflammatory mechanisms in the clearance of amyloid beta peptideQ34963822
Distribution, markers, and functions of retinal microgliaQ35014164
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomersQ35126030
Visual dysfunction, neurodegenerative diseases, and agingQ35293165
Transretinal degeneration in ageing human retina: a multiphoton microscopy analysisQ35525842
The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthoodQ35629245
Microglial response to amyloid plaques in APPsw transgenic mice.Q35764169
The microglial phagocytic role with specific plaque types in the Alzheimer disease brainQ35789675
Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucomaQ35858120
Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult miceQ36109567
Oxidative and antioxidative potential of brain microglial cells.Q36237582
Apoptosis is induced by beta-amyloid in cultured central nervous system neuronsQ36501389
Microglia activation in retinal degenerationQ36779168
Beta-amyloid deposition and functional impairment in the retina of the APPswe/PS1DeltaE9 transgenic mouse model of Alzheimer's diseaseQ36968718
Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantationQ37267731
Amyloid beta-protein toxicity and the pathogenesis of Alzheimer diseaseQ37310651
Alzheimer's disease and retinal neurodegeneration.Q37703319
Microglia in the healthy and degenerating retina: insights from novel mouse modelsQ37767283
Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer's diseaseQ37779106
Microglia in the CNS: immigrants from another worldQ37815122
Parallel findings in age-related macular degeneration and Alzheimer's diseaseQ37858172
Heterogeneity of CNS myeloid cells and their roles in neurodegenerationQ37939514
Early visual impairment is independent of the visuocognitive and memory disturbances in Alzheimer's diseaseQ38449564
Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxideQ41699826
Amyloid-peptide vaccinations reduce {beta}-amyloid plaques but exacerbate vascular deposition and inflammation in the retina of Alzheimer's transgenic miceQ42621245
Effects of prenatal ionizing irradiation on the development of the ganglion cell layer of the mouse retina.Q43621456
Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrilsQ43718666
Morphological and functional retinal impairment in Alzheimer's disease patientsQ43762429
Macrophage-derived factors stimulate optic nerve regeneration.Q44376583
Radiation-induced apoptosis in developing mouse retina exhibits dose-dependent requirement for ATM phosphorylation of p53.Q44749119
Retinal ganglion cell degeneration in Alzheimer's diseaseQ45168811
Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment.Q45881740
Kinetics of central nervous system microglial and macrophage engraftment: analysis using a transgenic bone marrow transplantation model.Q45882945
Retinal pathology in Alzheimer's disease. II. Regional neuron loss and glial changes in GCL.Q46006000
Age-related increase in mitochondrial DNA damage and loss of DNA repair capacity in the neural retinaQ46197412
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectbone marrowQ546523
retinal degenerationQ3043268
P304page(s)e64246
P577publication date2013-06-04
P1433published inPLOS OneQ564954
P1476titleSuppressed retinal degeneration in aged wild type and APPswe/PS1ΔE9 mice by bone marrow transplantation
P478volume8

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cites work (P2860)
Q38851309Friend or Foe? Resident Microglia vs Bone Marrow-Derived Microglia and Their Roles in the Retinal Degeneration
Q42327572Investigations into Retinal Pathology in the Early Stages of a Mouse Model of Alzheimer's Disease
Q39324141Microglia: Housekeeper of the Central Nervous System.
Q34043487Neuroprotective effect of the active components of three Chinese herbs on brain iron load in a mouse model of Alzheimer's disease
Q47595528Normal Amplitude of Electroretinography and Visual Evoked Potential Responses in AβPP/PS1 Mice.
Q28078670Ocular indicators of Alzheimer's: exploring disease in the retina
Q47221811Optical Coherence Tomography in Alzheimer's Disease and Other Neurodegenerative Diseases.
Q41845723Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer's disease
Q51760905Revolution of Alzheimer Precision Neurology Passageway of Systems Biology and Neurophysiology.
Q42642970Wild-type bone marrow transplant partially reverses neuroinflammation in progranulin-deficient mice

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