Microglia in the healthy and degenerating retina: insights from novel mouse models

scientific article published on 04 June 2010

Microglia in the healthy and degenerating retina: insights from novel mouse models is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/J.IMBIO.2010.05.010
P698PubMed publication ID20573418
P5875ResearchGate publication ID44697748

P2093author name stringThomas Langmann
Marcus Karlstetter
Stefanie Ebert
P433issue9-10
P407language of work or nameEnglishQ1860
P921main subjectmicrogliaQ1622829
P304page(s)685-691
P577publication date2010-06-04
P1433published inImmunobiologyQ15754985
P1476titleMicroglia in the healthy and degenerating retina: insights from novel mouse models
P478volume215

Reverse relations

cites work (P2860)
Q36346763A2E accumulation influences retinal microglial activation and complement regulation
Q34596350Absence of clinical correlates of diabetic retinopathy in the Ins2Akita retina.
Q35691959Accumulation and autofluorescence of phagocytized rod outer segment material in macrophages and microglial cells
Q51008421Activated adult microglia influence retinal progenitor cell proliferation and differentiation toward recoverin-expressing neuron-like cells in a co-culture model.
Q36278871Activation of glucocorticoid receptors in Müller glia is protective to retinal neurons and suppresses microglial reactivity
Q48392759Activation of retinal microglial cells is not associated with Müller cell reactivity in vitrectomized rabbit eyes
Q28395317Adaptive Müller cell responses to microglial activation mediate neuroprotection and coordinate inflammation in the retina
Q50332949Age-Related Macular Degeneration: New Paradigms for Treatment and Management of AMD.
Q37315838Aging is not a disease: distinguishing age-related macular degeneration from aging
Q55360712Alpha-1 Antitrypsin Attenuates M1 Microglia-Mediated Neuroinflammation in Retinal Degeneration.
Q92402690Amelioration of Mouse Retinal Degeneration After Blue LED Exposure by Glycyrrhizic Acid-Mediated Inhibition of Inflammation
Q92685284Amelioration of visual deficits and visual system pathology after mild TBI with the cannabinoid type-2 receptor inverse agonist SMM-189
Q36236460Analysis of Retinal Peripapillary Segmentation in Early Alzheimer's Disease Patients
Q28509210Animals deficient in C2Orf71, an autosomal recessive retinitis pigmentosa-associated locus, develop severe early-onset retinal degeneration
Q54072521Apelin activates the expression of inflammatory cytokines in microglial BV2 cells via PI-3K/Akt and MEK/Erk pathways.
Q55436808Are Anti-Retinal Autoantibodies a Cause or a Consequence of Retinal Degeneration in Autoimmune Retinopathies?
Q64241067Arginine to Glutamine Variant in Olfactomedin Like 3 () Is a Candidate for Severe Goniodysgenesis and Glaucoma in the Border Collie Dog Breed
Q91152883Blockade of microglial adenosine A2A receptor suppresses elevated pressure-induced inflammation, oxidative stress, and cell death in retinal cells
Q51312177Characterization of a Polymer-Based, Fully Organic Prosthesis for Implantation into the Subretinal Space of the Rat.
Q35068037Complement gene expression and regulation in mouse retina and retinal pigment epithelium/choroid
Q38804979Comprehensive analysis of mouse retinal mononuclear phagocytes.
Q33581991Conditional Müllercell ablation causes independent neuronal and vascular pathologies in a novel transgenic model
Q27007111Contribution of microglia-mediated neuroinflammation to retinal degenerative diseases
Q52589103Cystoid edema, neovascularization and inflammatory processes in the murine Norrin-deficient retina.
Q28511973Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration
Q36968685Early retinal inflammatory biomarkers in the middle cerebral artery occlusion model of ischemic stroke
Q41881865Elevated Glucose and Interleukin-1β Differentially Affect Retinal Microglial Cell Proliferation.
Q49397509Elevated Pressure Changes the Purinergic System of Microglial Cells.
Q97519130Exosomes derived from microglia exposed to elevated pressure amplify the neuroinflammatory response in retinal cells
Q94562610Exosomes derived from neural progenitor cells preserve photoreceptors during retinal degeneration by inactivating microglia
Q39031680Generation and characterization of immortalized rat retinal microglial cell lines
Q26827435Glia-neuron interactions in the mammalian retina
Q57471878Heterozygous Meg2 Ablation Causes Intraocular Pressure Elevation and Progressive Glaucomatous Neurodegeneration
Q36862089Human Müller glia with stem cell characteristics differentiate into retinal ganglion cell (RGC) precursors in vitro and partially restore RGC function in vivo following transplantation.
Q64071770Identification of the retinoschisin-binding site on the retinal Na/K-ATPase
Q42327751Immune modulation by MANF promotes tissue repair and regenerative success in the retina
Q58762327Immunomodulation with minocycline rescues retinal degeneration in juvenile neuronal ceroid lipofuscinosis mice highly susceptible to light damage
Q33651017Immunomodulation-accelerated neuronal regeneration following selective rod photoreceptor cell ablation in the zebrafish retina
Q36088090Immunosuppression, peripheral inflammation and invasive infection from endogenous gut microbiota activate retinal microglia in mouse models.
Q30620955In vivo multi-modal imaging of experimental autoimmune uveoretinitis in transgenic reporter mice reveals the dynamic nature of inflammatory changes during disease progression
Q37121011Increased Expression of Osteopontin in Retinal Degeneration Induced by Blue Light-Emitting Diode Exposure in Mice
Q36929063Insulin-like growth factor I (IGF-I)-induced chronic gliosis and retinal stress lead to neurodegeneration in a mouse model of retinopathy
Q34430102Interleukin 27 induces the expression of complement factor H (CFH) in the retina
Q34023023Isolation and ex vivo characterization of the immunophenotype and function of microglia/macrophage populations in normal dog retina
Q37381383LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity
Q37617417Macroglia-microglia interactions via TSPO signaling regulates microglial activation in the mouse retina
Q26828497Macrophages and Uveitis in Experimental Animal Models
Q41814116Microglia activation in a model of retinal degeneration and TUDCA neuroprotective effects
Q37739360Microglia activation is essential for BMP7-mediated retinal reactive gliosis.
Q93088329Microglia in Retinal Degeneration
Q34430952Microglia in mouse retina contralateral to experimental glaucoma exhibit multiple signs of activation in all retinal layers.
Q89143517Microglia inhibit photoreceptor cell death and regulate immune cell infiltration in response to retinal detachment
Q36389016Microglia-Müller cell interactions in the retina
Q35739792Microglial Activation Promotes Cell Survival in Organotypic Cultures of Postnatal Mouse Retinal Explants.
Q36678453Microglial aging in the healthy CNS: phenotypes, drivers, and rejuvenation
Q48332105Microglial dynamics after axotomy-induced retinal ganglion cell death
Q58728893Modulation of three key innate immune pathways for the most common retinal degenerative diseases
Q36971794Muller glia in retinal innate immunity: a perspective on their roles in endophthalmitis.
Q60047586Müller Cell Regulated Microglial Activation and Migration in Rats With -Methyl--Nitrosourea-Induced Retinal Degeneration
Q36181523Neonatal disease environment limits the efficacy of retinal transplantation in the LCA8 mouse model.
Q26798351Neuroinflammatory responses in diabetic retinopathy
Q36907135Neuropeptide Y receptors activation protects rat retinal neural cells against necrotic and apoptotic cell death induced by glutamate.
Q90692702Neuroprotective Strategies for Retinal Ganglion Cell Degeneration: Current Status and Challenges Ahead
Q92101608Occurrence of Transmembrane Protein 119 in the Retina is Not Restricted to the Microglia: An Immunohistochemical Study
Q43873491PACAP attenuates NMDA-induced retinal damage in association with modulation of the microglia/macrophage status into an acquired deactivation subtype
Q26796268Parainflammation, chronic inflammation, and age-related macular degeneration
Q41084355Persistent inflammatory state after photoreceptor loss in an animal model of retinal degeneration.
Q38871154Pleiotropic and retinoprotective functions of PACAP.
Q36182897Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling.
Q34170869Protective gene expression changes elicited by an inherited defect in photoreceptor structure
Q34172918Rapid light-induced activation of retinal microglia in mice lacking Arrestin-1.
Q52659809Re-programming immunosurveillance in persistent non-infectious ocular inflammation.
Q92567737Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina
Q34717672Reactive retinal microglia, neuronal survival, and the formation of retinal folds and detachments
Q38725575Retinal pigment epithelium and microglia express the CD5 antigen-like protein, a novel autoantigen in age-related macular degeneration.
Q91994298Saffron: A Multitask Neuroprotective Agent for Retinal Degenerative Diseases
Q61757974Selective A2A receptor antagonist prevents microglia-mediated neuroinflammation and protects retinal ganglion cells from high intraocular pressure–induced transient ischemic injury
Q36539094Small interfering RNA-mediated suppression of Ccl2 in Müller cells attenuates microglial recruitment and photoreceptor death following retinal degeneration.
Q90045275Spatial analysis of thickness changes in ten retinal layers of Alzheimer's disease patients based on optical coherence tomography
Q90473053Stabilization of myeloid-derived HIFs promotes vascular regeneration in retinal ischemia
Q34764098Suppressed retinal degeneration in aged wild type and APPswe/PS1ΔE9 mice by bone marrow transplantation
Q63435749Sweet Stress: Coping With Vascular Dysfunction in Diabetic Retinopathy
Q36231789Systemic immunotherapy delays photoreceptor cell loss and prevents vascular pathology in Royal College of Surgeons rats.
Q51736517Systemic inflammation induced by lipopolysaccharide aggravates inherited retinal dystrophy.
Q37262287Targeting the complement system for the management of retinal inflammatory and degenerative diseases.
Q39449147The Role of Microglia in Retinal Neurodegeneration: Alzheimer's Disease, Parkinson, and Glaucoma
Q96126473The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye
Q92236486The anti-inflammatory effect of minocycline on endotoxin-induced uveitis and retinal inflammation in rats
Q37708805The cell and molecular biology of glaucoma: mechanisms of retinal ganglion cell death
Q26781292The immune response of stem cells in subretinal transplantation
Q38077553The immunological basis of degenerative diseases of the eye.
Q38004034The role of glia in retinal vascular disease
Q49192854The role of microglia in the progression of glaucomatous neurodegeneration- a review
Q36018242Toll-like receptor 2 ligand pretreatment attenuates retinal microglial inflammatory response but enhances phagocytic activity toward Staphylococcus aureus
Q50952538Transplantation of CX3CL1-expressing mesenchymal stem cells provides neuroprotective and immunomodulatory effects in a rat model of retinal degeneration.
Q28066928Turning Down the Thermostat: Modulating the Endocannabinoid System in Ocular Inflammation and Pain

Search more.