Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach

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Possible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...864947H
P356DOI10.1371/JOURNAL.PONE.0064947
P932PMC publication ID3672143
P698PubMed publication ID23750220
P5875ResearchGate publication ID237093664

P50authorKatharina DomschkeQ21264133
Bertram Müller-MyhsokQ29840612
Susanne LucaeQ91202903
Volker AroltQ110551284
Sonja HorstmannQ125269120
Tanja BrücklQ125269447
Darina CzamaraQ37356516
Manfred UhrQ37358811
Marcus IsingQ37361882
Torsten KlengelQ42875669
Andreas MenkeQ47809940
Angela HeckQ47816002
Christiane WolfQ90469606
P2093author name stringBernhard T Baune
Anne Eckert
Martin A Kohli
Maria Giese
Johannes M Hennings
P2860cites workVariation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatmentQ24546379
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Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-AmericansQ33710367
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The corticosteroid receptor hypothesis of depressionQ34057906
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BDNF Val66Met genotype and 6-month remission rates in late-life depressionQ34233144
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Is it time to reassess the BDNF hypothesis of depression?Q34663655
Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depressionQ34740072
Novel sequence variations in the brain-derived neurotrophic factor gene and association with major depression and antidepressant treatment responseQ34743434
Antidepressants reverse corticosterone-mediated decrease in brain-derived neurotrophic factor expression: differential regulation of specific exons by antidepressants and corticosteroneQ34806426
A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depressionQ35737324
The bipolar spectrum and the antidepressant view of the worldQ36180345
Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patientsQ36965978
Brain-derived neurotrophic factor and its receptor tropomyosin-related kinase B in the mechanism of action of antidepressant therapiesQ36976169
Diagnostic guidelines for bipolar depression: a probabilistic approachQ37058580
The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study.Q37219127
Brain-derived neurotrophic factor and antidepressant action: another piece of evidence from pharmacogeneticsQ37264563
Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) projectQ38476657
Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicityQ40036871
Rational inferences about departures from Hardy-Weinberg equilibriumQ41826873
A note on the calculation of empirical P values from Monte Carlo procedures.Q43202630
Increased stress reactivity is associated with cognitive deficits and decreased hippocampal brain-derived neurotrophic factor in a mouse model of affective disordersQ43207305
Association of brain-derived neurotrophic factor genetic Val66Met polymorphism with severity of depression, efficacy of fluoxetine and its side effects in Chinese major depressive patientsQ43218136
Diagnostic conversion from depression to bipolar disorders: results of a long-term prospective study of hospital admissionsQ43922336
Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects.Q44270223
Association study of a brain-derived neurotrophic-factor genetic polymorphism and mood disorders, age of onset and suicidal behaviorQ44691711
SNPs in neurotrophin system genes and Alzheimer's disease in an Italian populationQ44865775
No association between the Val66Met polymorphism of the brain-derived neurotrophic factor gene and bipolar disorder in a Japanese population: a multicenter study.Q45035951
Genetic predictors of increase in suicidal ideation during antidepressant treatment in the GENDEP project.Q45916412
Brain-derived neurotrophic factor gene polymorphisms and mirtazapine responses in Koreans with major depression.Q45984035
Genetic predictors of response to antidepressants in the GENDEP projectQ46051862
Brain-derived neurotrophic factor ( BDNF) gene: no major impact on antidepressant treatment responseQ46112497
Suppressive effect of mirtazapine on the HPA system in acutely depressed women seems to be transient and not related to antidepressant actionQ46313005
Profiling of behavioral changes and hippocampal gene expression in mice chronically treated with the SSRI paroxetineQ46482293
A brain-derived neurotrophic factor (BDNF) haplotype is associated with antidepressant treatment outcome in mood disorders.Q48166495
A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depressionQ48187724
Pharmacologically diverse antidepressants rapidly activate brain-derived neurotrophic factor receptor TrkB and induce phospholipase-Cgamma signaling pathways in mouse brainQ48266494
Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone.Q48345283
The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamineQ48375775
Gene-gene interactions of the brain-derived neurotrophic-factor and neurotrophic tyrosine kinase receptor 2 genes in geriatric depressionQ48377411
Association study of the brain-derived neurotrophic factor (BDNF) gene with bipolar disorderQ48411017
Brain-derived neurotrophic factor gene polymorphism (Val66Met) and citalopram response in major depressive disorderQ48419893
Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolismQ48440447
The effects of acute and long-term lithium treatments on trkB neurotrophin receptor activation in the mouse hippocampus and anterior cingulate cortexQ48689480
Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depressionQ48819378
Brain-derived neurotrophic factor gene polymorphisms: influence on treatment response phenotypes of major depressive disorderQ48941703
The early non-increase of serum BDNF predicts failure of antidepressant treatment in patients with major depression: a pilot studyQ49073147
Extensive genotyping of the BDNF and NTRK2 genes define protective haplotypes against obsessive-compulsive disorderQ51736448
Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatmentsQ52012874
Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampusQ52017804
Combined Dexamethasone/Corticotropin Releasing Hormone Test Predicts Treatment Response in Major Depression–A Potential Biomarker?Q60631384
Association study of neurotrophic tyrosine kinase receptor type 2 (NTRK2) and childhood-onset mood disordersQ61570858
Association of the COMT val158met variant with antidepressant treatment response in major depressionQ80376629
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)e64947
P577publication date2013-06-04
P1433published inPLOS OneQ564954
P1476titlePossible associations of NTRK2 polymorphisms with antidepressant treatment outcome: findings from an extended tag SNP approach
P478volume8

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cites work (P2860)
Q94464650An Analysis of Five TrkB Gene Polymorphisms in Schizophrenia and the Interaction of Its Haplotype with rs6265 BDNF Gene Polymorphism
Q90857194BDNF genetic variants and methylation: effects on cognition in major depressive disorder
Q38540142BDNF/TRKB/P75NTR polymorphisms and their consequences on antidepressant efficacy in depressed patients.
Q40314455No impact of eight NTRK2 genetic polymorphisms on 6-month antidepressant efficacy in depressed patients.
Q38983579Pharmacogenetics and Imaging-Pharmacogenetics of Antidepressant Response: Towards Translational Strategies.
Q47666907Progress in Elucidating Biomarkers of Antidepressant Pharmacological Treatment Response: A Systematic Review and Meta-analysis of the Last 15 Years
Q34424865Understanding the pharmacogenetics of selective serotonin reuptake inhibitors

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