Tumor necrosis factor-α promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase-1 production in hepatic stellate cells

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Tumor necrosis factor-α promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase-1 production in hepatic stellate cells is …
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scholarly articleQ13442814

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P819ADS bibcode2013PLoSO...865251O
P356DOI10.1371/JOURNAL.PONE.0065251
P932PMC publication ID3670853
P698PubMed publication ID23755201
P5875ResearchGate publication ID237098612

P2093author name stringIchiro Yasuda
Masato Hoshi
Hisataka Moriwaki
Osamu Kozawa
Toshiji Saibara
Yosuke Osawa
P2860cites workThe role of tumor necrosis factor-alpha in liver toxicity, inflammation, and fibrosis induced by carbon tetrachlorideQ23919498
Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in ratsQ28571978
Glutathione depletion is involved in the inhibition of procollagen alpha1(I) mRNA levels caused by TNF-alpha on hepatic stellate cellsQ28579226
Liver fibrosisQ29547449
Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transitionQ32075959
Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosisQ33984201
Hepatic stellate cells as a target for the treatment of liver fibrosisQ34391409
Roles for C16-ceramide and sphingosine 1-phosphate in regulating hepatocyte apoptosis in response to tumor necrosis factor-alphaQ34425224
Tissue inhibitor of metalloproteinase 1 (TIMP-1) deficiency exacerbates carbon tetrachloride-induced liver injury and fibrosis in mice: involvement of hepatocyte STAT3 in TIMP-1 productionQ35073951
Bile acid regulation of hepatic physiology: IV. Bile acids and death receptorsQ35102867
Tumour necrosis factor alpha signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in miceQ35760220
Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptorQ35997495
TIMP-1 deficiency leads to lethal partial hepatic ischemia and reperfusion injuryQ36067201
Mechanisms of Liver Injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathwaysQ36421523
"Let there be bile"--understanding hepatic injury in cholestasisQ36526816
Liver acid sphingomyelinase inhibits growth of metastatic colon cancerQ36580354
Tissue inhibitors of metalloproteinases in cell signaling: metalloproteinase-independent biological activities.Q36805538
Critical role of tumor necrosis factor receptor 1, but not 2, in hepatic stellate cell proliferation, extracellular matrix remodeling, and liver fibrogenesisQ39552232
Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis.Q39632325
Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in miceQ40310360
Possible involvement of reactive oxygen species in D-galactosamine-induced sensitization against tumor necrosis factor-alpha-induced hepatocyte apoptosisQ40810309
Stress-activated protein kinases in the activation of rat hepatic stellate cells in culture.Q40891185
Upstream tissue inhibitor of metalloproteinases-1 (TIMP-1) element-1, a novel and essential regulatory DNA motif in the human TIMP-1 gene promoter, directly interacts with a 30-kDa nuclear protein.Q40897756
Tumor necrosis factor alpha inhibits collagen alpha 1(I) gene expression in rat hepatic stellate cells through a G proteinQ41097795
Distinct mechanisms regulate TIMP-1 expression at different stages of phorbol ester-mediated differentiation of U937 cellsQ41121291
TNFalpha is required for cholestasis-induced liver fibrosis in the mouseQ41339503
Loss of orphan receptor small heterodimer partner sensitizes mice to liver injury from obstructive cholestasisQ42526474
Role of acid sphingomyelinase of Kupffer cells in cholestatic liver injury in miceQ43263378
Caspase activation during hepatocyte apoptosis induced by tumor necrosis factor-alpha in galactosamine-sensitized miceQ43758752
Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapyQ43786938
Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migrationQ44493296
TNF-alpha inhibits liver collagen-alpha 1(I) gene expression through a tissue-specific regulatory regionQ46183132
Lack of tumor necrosis factor receptor type 1 inhibits liver fibrosis induced by carbon tetrachloride in miceQ46370419
Roles of AKT and sphingosine kinase in the antiapoptotic effects of bile duct ligation in mouse liverQ46827700
Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosisQ48062721
Serotonin protects mouse liver from cholestatic injury by decreasing bile salt pool after bile duct ligationQ57546894
Metalloproteinase inhibitor TIMP-1 affects hepatocyte cell cycle via HGF activation in murine liver regenerationQ58211740
Tumor necrosis factor alpha prevents tumor necrosis factor receptor-mediated mouse hepatocyte apoptosis, but not fas-mediated apoptosis: role of nuclear factor-kappaBQ64380270
Cytokines tumor necrosis factor and interleukin-6 in experimental biliary obstruction in miceQ68134831
Tissue inhibitor of metalloproteinases-1 promotes liver fibrosis development in a transgenic mouse modelQ73229679
Lethal hepatic apoptosis mediated by tumor necrosis factor receptor, unlike Fas-mediated apoptosis, requires hepatocyte sensitization in miceQ73288585
Control of the tissue inhibitor of metalloproteinases-1 promoter in culture-activated rat hepatic stellate cells: regulation by activator protein-1 DNA binding proteinsQ74529972
Inflammation in response to hepatocellular apoptosisQ77823653
Expression patterns of matrix metalloproteinases and their inhibitors in parenchymal and non-parenchymal cells of rat liver: regulation by TNF-alpha and TGF-beta1Q77932181
Systemic mediators induce fibrogenic effects in normal liver after partial bile duct ligationQ79219306
Cytokine blockade inhibits hepatic tissue inhibitor of metalloproteinase-1 expression and up-regulates matrix metalloproteinase-9 in toxic liver injuryQ83951399
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)e65251
P577publication date2013-06-03
P1433published inPLOS OneQ564954
P1476titleTumor necrosis factor-α promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase-1 production in hepatic stellate cells
P478volume8

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cites work (P2860)
Q92048632A Novel Hepatic Anti-Fibrotic Strategy Utilizing the Secretome Released from Etanercept-Synthesizing Adipose-Derived Stem Cells
Q59359696Adeno-Associated Virus-Mediated Gene Transfer of Tissue Inhibitor of Metalloproteinases-1 Impairs Neutrophil Extracellular Trap Formation and Ameliorates Hepatic Ischemia and Reperfusion Injury
Q35980026Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1β or TNF-α Release from Human Hepatic Stellate Cells
Q58580917Conditioned Medium from Human Amnion-Derived Mesenchymal Stem Cells Regulates Activation of Primary Hepatic Stellate Cells
Q38303313Early to Phase II drugs currently under investigation for the treatment of liver fibrosis
Q38220772Hedgehog signaling pathway as key player in liver fibrosis: new insights and perspectives
Q94525578Hepatic Fibrosis Assessed Using Fibrosis-4 Index Is Predictive of All-Cause Mortality in Patients with Chronic Obstructive Pulmonary Disease
Q57494347Hepatic effect of sofosbuvir and daclatasvir in thioacetamide-induced liver injury in rats
Q35213917Hepatic inflammation and fibrosis: functional links and key pathways
Q41979567Improved Hepatoprotective Effect of Liposome-Encapsulated Astaxanthin in Lipopolysaccharide-Induced Acute Hepatotoxicity
Q36541005Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/β-Catenin Reduces Liver Fibrosis in Mice.
Q89624108Liver fibrosis and CD206+ macrophage accumulation are suppressed by anti-GM-CSF therapy
Q97423692MicroRNA-98 Inhibits Hepatic Stellate Cell Activation and Attenuates Liver Fibrosis by Regulating HLF Expression
Q28070168New Concepts on Pathogenesis and Diagnosis of Liver Fibrosis; A Review Article
Q33706254Nonalcoholic fatty liver disease: Diagnostic biomarkers.
Q64067609P38 inhibition reverses TGFβ1 and TNFα-induced contraction in a model of proliferative vitreoretinopathy
Q51300509Protective effect of ursodeoxycholic acid, resveratrol, and N-acetylcysteine on nonalcoholic fatty liver disease in rats.
Q41813284Synergistic effect of pro-inflammatory TNFα and IL-17 in periostin mediated collagen deposition: potential role in liver fibrosis
Q38685726TNFα in liver fibrosis
Q38179983The significance of YKL-40 protein in liver fibrosis
Q52605838Tumor necrosis factor-α-mediated hepatocyte apoptosis stimulates fibrosis in the steatotic liver in mice.
Q57152398Vitamin K1 attenuates bile duct ligation-induced liver fibrosis in rats
Q48695566WITHDRAWN: The role of TNFα in promoting hepatic MRP4 expression via the p38-Rb-E2F1 pathway in human obstructive cholestasis
Q64230111and its monomers alleviate liver fibrosis both in mice and LX2 cells by blocking TβR1-Smad2/3 and TNF-α-NF-κB pathways

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