scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1016/S0920-1211(02)00076-1 |
P698 | PubMed publication ID | 12151125 |
P50 | author | Asla Pitkänen | Q23039734 |
P2860 | cites work | Felbamate in experimental model of status epilepticus | Q28371394 |
The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS | Q28570728 | ||
Anticonvulsant action and long-term effects of gabapentin in the immature brain | Q31562313 | ||
Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials | Q34083116 | ||
A permanent change in brain function resulting from daily electrical stimulation | Q34225550 | ||
Does convulsive status epilepticus (SE) result in cerebral damage or affect the course of epilepsy--the epidemiological and clinical evidence? | Q34764014 | ||
Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy | Q35172480 | ||
Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures | Q36587338 | ||
Enhanced GABAergic inhibition preserves hippocampal structure and function in a model of epilepsy | Q37585904 | ||
Analyses of the molecular basis of kindling development | Q40976883 | ||
Isoflurane delays but does not prevent cerebral infarction in rats subjected to focal ischemia | Q41732296 | ||
Comparison of the anticonvulsant efficacy of primidone and phenobarbital during chronic treatment of amygdala-kindled rats | Q41899462 | ||
Phenobarbital modifies seizure-related brain injury in the developing brain | Q42284193 | ||
Posthypoxic treatment with felbamate is neuroprotective in a rat model of hypoxia-ischemia | Q42286535 | ||
Diazepam, given postischemia, protects selectively vulnerable neurons in the rat hippocampus and striatum. | Q42488010 | ||
Zonisamide as a neuroprotective agent in an adult gerbil model of global forebrain ischemia: a histological, in vivo microdialysis and behavioral study | Q42546501 | ||
Felbamate protects CA1 neurons from apoptosis in a gerbil model of global ischemia | Q42555632 | ||
Tolerance to the anticonvulsant effects of lamotrigine on amygdala kindled seizures: cross-tolerance to carbamazepine but not valproate or diazepam | Q42622780 | ||
A reversible type of neuronal injury following ischemia in the gerbil hippocampus | Q43524490 | ||
Chronic elevation of brain GABA levels beginning two days after status epilepticus does not prevent epileptogenesis in rats | Q43543021 | ||
Tiagabine treatment and DNA damage in rat astrocytes: an in vitro study by comet assay. | Q43638388 | ||
Effect of lamotrigine treatment on status epilepticus-induced neuronal damage and memory impairment in rat. | Q43716931 | ||
Thiopentone and methohexital, but not pentobarbitone, reduce early focal cerebral ischemic injury in rats | Q43730331 | ||
Topiramate blocks perinatal hypoxia-induced seizures in rat pups | Q43738767 | ||
Vigabatrin protects against hippocampal damage but is not antiepileptogenic in the lithium-pilocarpine model of temporal lobe epilepsy | Q43774639 | ||
Recurrent spontaneous motor seizures after repeated low-dose systemic treatment with kainate: assessment of a rat model of temporal lobe epilepsy | Q44056599 | ||
Delayed sclerosis, neuroprotection, and limbic epileptogenesis after status epilepticus in the rat. | Q44066396 | ||
A prospective, population-based epidemiologic study of status epilepticus in Richmond, Virginia | Q44155514 | ||
Antiepileptogenic effects of conventional anticonvulsants in the kindling model of epilespy | Q45284051 | ||
A neuropharmacological evaluation of felbamate as a novel anticonvulsant | Q45762537 | ||
Stimulation-dependent effect of antiepileptic drugs in amygdala kindled rats on both seizure score and duration of afterdischarges | Q48096067 | ||
Postischemic diazepam is neuroprotective in the gerbil hippocampus | Q48120673 | ||
Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents | Q48122183 | ||
Topiramate reduces neuronal injury after experimental status epilepticus | Q48144553 | ||
Hippocampal kindling protects several structures from the neuronal damage resulting from kainic acid-induced status epilepticus | Q48188916 | ||
Phenytoin reduces neonatal hypoxic-ischemic brain damage in rats | Q48195751 | ||
Oxcarbazepine: preclinical anticonvulsant profile and putative mechanisms of action | Q48214421 | ||
Neuroprotective effect of remacemide hydrochloride in a perforant pathway stimulation model of status epilepticus in the rat. | Q48233119 | ||
Halothane as a neuroprotectant during constant stimulation of the perforant path | Q48261949 | ||
Anti-seizure and anti-epileptogenic effect of gamma-vinyl gamma-aminobutyric acid in amygdaloid kindling | Q48275112 | ||
Effects of vigabatrin treatment on status epilepticus-induced neuronal damage and mossy fiber sprouting in the rat hippocampus | Q48282146 | ||
Valproate robustly enhances AP-1 mediated gene expression | Q48305334 | ||
PNU-151774E protects against kainate-induced status epilepticus and hippocampal lesions in the rat. | Q48341596 | ||
Neuroprotection by delayed administration of topiramate in a rat model of middle cerebral artery embolization | Q48384000 | ||
Antiepileptic effects of topiramate on amygdaloid kindling in rats | Q48406834 | ||
Effects of lamotrigine and conventional antiepileptic drugs on amygdala- and hippocampal-kindled seizures in rats | Q48406844 | ||
Alteration of long-lasting structural and functional effects of kainic acid in the hippocampus by brief treatment with phenobarbital | Q48413498 | ||
Comparison of valproate and phenobarbital treatment after status epilepticus in rats | Q48425188 | ||
Protective effect of zonisamide, an antiepileptic drug, against transient focal cerebral ischemia with middle cerebral artery occlusion-reperfusion in rats | Q48473716 | ||
The Effects of Propofol on Brain Electrical Activity, Neurologic Outcome, and Neuronal Damage Following Incomplete Ischemia in Rats | Q48531776 | ||
BW1003C87, phenytoin and carbamazepine elevate seizure threshold in the rat amygdala-kindling model of epilepsy | Q48551095 | ||
Lamotrigine protects hippocampal CA1 neurons from ischemic damage after cardiac arrest | Q48594740 | ||
Tiagabine exerts an anti-epileptogenic effect in amygdala kindling epileptogenesis in the rat. | Q48681077 | ||
Vigabatrin pre-treatment prevents hilar somatostatin cell loss and the development of interictal spiking activity following sustained simulation of the perforant path | Q48703486 | ||
Enhancement of GABA neurotransmission after cerebral ischemia in the rat reduces loss of hippocampal CA1 pyramidal cells | Q48704481 | ||
Postischemic seizures and necrotizing ischemic brain damage: neuroprotective effect of postischemic diazepam and insulin | Q48777633 | ||
The effect of lamotrigine upon development of cortical kindled seizures in the rat | Q48786817 | ||
Seizure-induced damage to the hippocampus is prevented by modulation of the GABAergic system. | Q48943169 | ||
Anticonvulsant drugs selectively affect kindled and penicillin epilepsy, especially during seizure-prone sleep or awakening states in cats | Q48947155 | ||
Neuroprotective effects of felbamate on global ischaemia in Mongolian gerbils | Q48968065 | ||
Tiagabine prevents seizures, neuronal damage and memory impairment in experimental status epilepticus | Q49050748 | ||
The neuroprotective effects of gamma-vinyl GABA in transient global ischemia: a morphological study with early and delayed evaluations | Q49121477 | ||
Anticonvulsant effects of zonisamide and phenytoin on seizure activity of the feline visual cortex. | Q49155081 | ||
Lamotrigine treatment during amygdala-kindled seizure development fails to inhibit seizures and diminishes subsequent anticonvulsant efficacy | Q49158046 | ||
Risk of unprovoked seizure after acute symptomatic seizure: effect of status epilepticus. | Q50852990 | ||
Anesthetic effects on cerebral metabolic rate predict histologic outcome from near-complete forebrain ischemia in the rat. | Q51390326 | ||
Protective effect of etomidate on kainic acid-induced neurotoxicity in rat hippocampus. | Q51399149 | ||
Effect of 2,6-diisopropylphenol on the delayed hippocampal cell loss following transient forebrain ischemia in the gerbil. | Q51582665 | ||
Relationship between the dose-response effects of diazepam and clobazam on electroencephalographic parameters and on kindled amygdaloid seizure activity in rats. | Q51766225 | ||
Quinolinic acid-induced seizures, but not nerve cell death, are associated with extracellular Ca2+ decrease assessed in the hippocampus by brain dialysis. | Q51770926 | ||
Effects of clobazam on amygdaloid and hippocampal kindled seizures in rats. | Q51790609 | ||
The role of epileptic activity in hippocampal and "remote" cerebral lesions induced by kainic acid. | Q51875842 | ||
A new model of chronic temporal lobe epilepsy induced by electrical stimulation of the amygdala in rat. | Q52029733 | ||
Carbamazepine and carbamazepine-10,11-epoxide inhibit amygdala-kindled seizures in the rat but do not block their development. | Q52074613 | ||
Failure of carbamazepine to prevent behavioural and histopathological sequels of experimentally induced status epilepticus. | Q52202679 | ||
Neuroprotective properties of the novel antiepileptic lamotrigine in a gerbil model of global cerebral ischemia. | Q52209617 | ||
The new antiepileptic drugs lamotrigine and felbamate are effective in phenytoin-resistant kindled rats. | Q54045309 | ||
Development of a new pharmacological seizure model: effects of anticonvulsants on cortical- and amygdala-kindled seizures in the rat. | Q54544637 | ||
National General Practice Study of Epilepsy (NGPSE): partial seizure patterns in a general population | Q67561030 | ||
Inhibition or enhancement of kindling evolution by antiepileptics | Q68508087 | ||
Anticonvulsant and proconvulsant effects of inhibitors of GABA degradation in the amygdala-kindling model | Q69649999 | ||
Electroencephalographic burst suppression is not required to elicit maximal neuroprotection from pentobarbital in a rat model of focal cerebral ischemia | Q71158948 | ||
Postischemic inhibition of GABA reuptake by tiagabine slows neuronal death in the gerbil hippocampus | Q71443626 | ||
Topiramate: a potent anticonvulsant in the amygdala-kindled rat | Q71510432 | ||
Vigabatrin and carbamazepine have different efficacies in the prevention of status epilepticus induced neuronal damage in the hippocampus and amygdala | Q71519197 | ||
Vigabatrin protects against kainic acid-induced neuronal damage in the rat hippocampus | Q71526019 | ||
Neuroprotective effects of lamotrigine in global ischemia in gerbils. A histological, in vivo microdialysis and behavioral study | Q71625626 | ||
Cerebroprotective effect of lamotrigine after focal ischemia in rats | Q72486597 | ||
Anticonvulsant activity of PNU-151774E in the amygdala kindled model of complex partial seizures | Q73192026 | ||
Different mechanisms of protection against apoptosis by valproate and Li+ | Q73231420 | ||
Protective effect of topiramate against hippocampal neuronal damage after global ischemia in the gerbils | Q73515499 | ||
Comparison of the preclinical anticonvulsant profiles of tiagabine, lamotrigine, gabapentin and vigabatrin | Q73583786 | ||
Usefulness of postischemic thrombolysis with or without neuroprotection in a focal embolic model of cerebral ischemia | Q73742132 | ||
Dose-dependent neuroprotection with tiagabine in a focal cerebral ischemia model in rat | Q74102484 | ||
Neuroprotective activity of tiagabine in a focal embolic model of cerebral ischemia | Q74146473 | ||
P433 | issue | 1-2 | |
P921 | main subject | neurodegeneration | Q1755122 |
P304 | page(s) | 141-160 | |
P577 | publication date | 2002-06-01 | |
P1433 | published in | Epilepsy Research | Q15746405 |
P1476 | title | Efficacy of current antiepileptics to prevent neurodegeneration in epilepsy models | |
P478 | volume | 50 |
Q46433914 | A spontaneous recurrent seizure bioassay for anti-epileptogenic molecules. |
Q37821330 | AED discontinuation may not be dangerous in seizure-free patients |
Q34768821 | Animal models of epilepsy for the development of antiepileptogenic and disease-modifying drugs. A comparison of the pharmacology of kindling and post-status epilepticus models of temporal lobe epilepsy |
Q34461434 | Antiepileptic drugs and neuroprotection: current status and future roles |
Q34768826 | Antiepileptic drugs to prevent neural degeneration associated with epilepsy: assessing the prospects for neuroprotection |
Q45281121 | Antiepileptic effects of botulinum neurotoxin E. |
Q37387640 | Effect of topiramate on interleukin 6 expression in the hippocampus of amygdala-kindled epileptic rats |
Q47585978 | Effects of the novel antiepileptic drug lacosamide on the development of amygdala kindling in rats |
Q44568833 | Epileptogenesis and neuropathology after different types of status epilepticus induced by prolonged electrical stimulation of the basolateral amygdala in rats |
Q43166926 | Evaluation of the anticonvulsant effect of Centella asiatica (gotu kola) in pentylenetetrazol-induced seizures with respect to cholinergic neurotransmission |
Q44597438 | Expression and activation of caspase 3 following status epilepticus in the rat. |
Q46911546 | Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system. |
Q49098983 | Hydroalcoholic extract of Zizyphus jujuba ameliorates seizures, oxidative stress, and cognitive impairment in experimental models of epilepsy in rats |
Q44885666 | Implementing a bioassay to screen molecules for antiepileptogenic activity: chronic pilocarpine versus subdudral haematoma models |
Q34427274 | Increased metallothionein I/II expression in patients with temporal lobe epilepsy |
Q44413809 | N-methyl-D-aspartate receptor blockade after status epilepticus protects against limbic brain damage but not against epilepsy in the kainate model of temporal lobe epilepsy |
Q36470506 | Neuropathology in Drosophila mutants with increased seizure susceptibility |
Q38684428 | Neuroprotection as a Potential Therapeutic Perspective in Neurodegenerative Diseases: Focus on Antiepileptic Drugs |
Q43272192 | Neuroprotective effects of IGF-I following kainic acid-induced hippocampal degeneration in the rat. |
Q38164039 | Pathophysiogenesis of mesial temporal lobe epilepsy: is prevention of damage antiepileptogenic? |
Q37867301 | Pharmacological management of seizures and status epilepticus in critically ill patients. |
Q36106892 | Primary prevention of epilepsy in patients with different epileptogenic conditions |
Q30954039 | Progression of brain damage after status epilepticus and its association with epileptogenesis: a quantitative MRI study in a rat model of temporal lobe epilepsy |
Q35688753 | Should antiepileptic drugs be withdrawn in seizure-free patients? |
Q51574148 | Striking differences in individual anticonvulsant response to phenobarbital in rats with spontaneous seizures after status epilepticus. |
Q88635162 | Taurine Protects from Pentylenetetrazole-Induced Behavioral and Neurochemical Changes in Zebrafish |
Q35824087 | The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions. |
Q44193576 | Transient increase of P-glycoprotein expression in endothelium and parenchyma of limbic brain regions in the kainate model of temporal lobe epilepsy |
Q37714086 | Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders. |
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