The role of Cdk5 in cognition and neuropsychiatric and neurological pathology

scientific article

The role of Cdk5 in cognition and neuropsychiatric and neurological pathology is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.BRAINRESBULL.2010.11.016
P932PMC publication ID3073157
P698PubMed publication ID21145377
P5875ResearchGate publication ID49671339

P2093author name stringJames A Bibb
David G S Barnett
P2860cites workPhosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neuronsQ22010952
Alzheimer Disease in the US PopulationQ22253055
Phosphorylation of protein phosphatase inhibitor-1 by Cdk5Q24091381
The cyclin-dependent kinase 5 activators p35 and p39 interact with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin-1 in a calcium-dependent mannerQ24306574
Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant pathQ24538964
Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapsesQ24597922
Cell biology of Ca2+-triggered exocytosisQ26269905
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegenerationQ28140796
Retinoblastoma protein recruits histone deacetylase to repress transcriptionQ28262144
Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse numberQ28297899
Regulation of hippocampal and behavioral excitability by cyclin-dependent kinase 5.Q28389221
Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradationQ28506134
Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.Q53571110
Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosisQ57834817
Dopamine and cAMP-regulated phosphoprotein 32 kDa controls both striatal long-term depression and long-term potentiation, opposing forms of synaptic plasticityQ63256021
Regulation of NMDA receptors by cyclin-dependent kinase-5Q28567371
Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEPQ28567752
Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5Q28568627
Cdk5-Mediated Inhibition of the Protective Effects of Transcription Factor MEF2 in Neurotoxicity-Induced ApoptosisQ28571515
Cdk5 is essential for synaptic vesicle endocytosisQ28579572
Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptorsQ28582006
Histone acetyltransferasesQ29547823
Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatumQ29620475
Phosphoproteome and transcriptome analysis of the neuronal response to a CDK5 inhibitorQ31147426
Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination.Q32063419
No difference in kinetics of tau or histone phosphorylation by CDK5/p25 versus CDK5/p35 in vitroQ33733724
Activity-dependent bulk endocytosis and clathrin-dependent endocytosis replenish specific synaptic vesicle pools in central nerve terminalsQ33929652
Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles.Q33948657
Deregulation of HDAC1 by p25/Cdk5 in neurotoxicityQ34028507
A decade of CDK5.Q34093501
Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tanglesQ34279396
A mechanism for the Hebb and the anti-Hebb processes underlying learning and memoryQ34324150
The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosisQ34416249
Life is a journey: a genetic look at neocortical developmentQ34623765
Cocaine regulates MEF2 to control synaptic and behavioral plasticityQ34818266
Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5.Q34977401
The phospho-dependent dynamin-syndapin interaction triggers activity-dependent bulk endocytosis of synaptic vesiclesQ34987475
Endocytosis at the synaptic terminal.Q35215005
Cognition enhancement strategiesQ36182249
Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinasesQ36321493
Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processingQ36579740
Modes of vesicle retrieval at ribbon synapses, calyx-type synapses, and small central synapsesQ36989207
Cdk5-mediated phosphorylation of delta-catenin regulates its localization and GluR2-mediated synaptic activityQ37616216
Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses.Q39751968
Fragile X mental retardation protein is required for synapse elimination by the activity-dependent transcription factor MEF2.Q40372504
Truncation of CDK5 activator p35 induces intensive phosphorylation of Ser202/Thr205 of human tau.Q40704620
Bulk synaptic vesicle endocytosis is rapidly triggered during strong stimulationQ41599069
CDK5 serves as a major control point in neurotransmitter release.Q41862687
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.Q43553698
Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity.Q43940169
Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons.Q44746561
Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2.Q46890595
A brain-specific activator of cyclin-dependent kinase 5.Q48079027
Enhanced activation of Ca2+/calmodulin-dependent protein kinase II upon downregulation of cyclin-dependent kinase 5-p35.Q48486674
P433issue1-2
P921main subjectpathologyQ7208
P304page(s)9-13
P577publication date2010-12-07
P1433published inBrain Research BulletinQ4955784
P1476titleThe role of Cdk5 in cognition and neuropsychiatric and neurological pathology
P478volume85

Reverse relations

cites work (P2860)
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