Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

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Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1000735387
P356DOI10.1038/35066591
P698PubMed publication ID11268215
P5875ResearchGate publication ID12065277

P50authorPaul GreengardQ309979
Eric J. NestlerQ5386788
Per SvenningssonQ21175215
Angus C. NairnQ37621746
P2093author name stringJ Chen
A Nishi
G L Snyder
J A Bibb
Z Yan
J R Taylor
C C Ouimet
Z K Sagawa
P2860cites workNMDA induces long-term synaptic depression and dephosphorylation of the GluR1 subunit of AMPA receptors in hippocampusQ48327089
Transgenic animals with inducible, targeted gene expression in brainQ48398754
Phosphorylation of DARPP-32 and protein phosphatase inhibitor-1 in rat choroid plexus: regulation by factors other than dopamineQ48449212
Opposite modulation of opiate withdrawal behaviors on microinfusion of a protein kinase A inhibitor versus activator into the locus coeruleus or periaqueductal gray.Q48617076
ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteinsQ56503354
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neuronsQ56568483
D1 and D2 dopamine receptor gene expression in the rat striatum: Sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAS in distinct neuronal populations of the dorsal and ventral striatumQ61762612
Role of D1 and D2 dopamine receptors in mediating locomotor activity elicited from the nucleus accumbens of ratsQ69304549
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neuronsQ22010952
Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patchesQ22337395
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegenerationQ28140796
Amplification of dopaminergic signaling by a positive feedback loopQ28142174
Addiction, dopamine, and the molecular mechanisms of memoryQ28142501
Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunitQ28282250
Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethalityQ28302232
Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant miceQ28372752
Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal deathQ28587075
Elimination of cocaine-induced hyperactivity and dopamine-mediated neurophysiological effects in dopamine D1 receptor mutant miceQ28591400
Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaineQ33875193
Opposite modulation of cocaine-seeking behavior by D1- and D2-like dopamine receptor agonistsQ34374970
FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effectsQ36586953
Molecular mechanisms of opiate and cocaine addictionQ41652306
Whole-cell plasticity in cocaine withdrawal: reduced sodium currents in nucleus accumbens neurons.Q42448634
Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal gangliaQ42489217
Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments.Q47650443
Region-specific expression of cyclin-dependent kinase 5 (cdk5) and its activators, p35 and p39, in the developing and adult rat central nervous systemQ48038238
Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor.Q48218197
Enhanced responding for conditioned reward produced by intra-accumbens amphetamine is potentiated after cocaine sensitizationQ48248680
P433issue6826
P407language of work or nameEnglishQ1860
P304page(s)376-380
P577publication date2001-03-01
P1433published inNatureQ180445
P1476titleEffects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.
P478volume410

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