| scholarly article | Q13442814 |
| P50 | author | Anjaneyulu Kowluru | Q37368890 |
| P2093 | author name string | Anjaneyulu Kowluru | |
| P2860 | cites work | rac, a novel ras-related family of proteins that are botulinum toxin substrates | Q24339158 |
| GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo | Q24685451 | ||
| Identification of an IQGAP1/AKAP79 complex in beta-cells | Q27863770 | ||
| Dominant-negative alpha-subunit of farnesyl- and geranyltransferase inhibits glucose-stimulated, but not KCl-stimulated, insulin secretion in INS 832/13 cells | Q28570363 | ||
| Regulatory roles for Tiam1, a guanine nucleotide exchange factor for Rac1, in glucose-stimulated insulin secretion in pancreatic beta-cells | Q28578486 | ||
| Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2 | Q28609631 | ||
| NADPH oxidase: an update | Q28611494 | ||
| Small GTP-binding proteins | Q29547372 | ||
| Menin interacts with IQGAP1 to enhance intercellular adhesion of beta-cells | Q30438923 | ||
| Elusive proximal signals of beta-cells for insulin secretion | Q37998147 | ||
| Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion | Q39157906 | ||
| Stimulus-dependent regulation of the phagocyte NADPH oxidase by a VAV1, Rac1, and PAK1 signaling axis. | Q40030757 | ||
| Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line | Q40199579 | ||
| Biologically active lipids promote trafficking and membrane association of Rac1 in insulin-secreting INS 832/13 cells | Q40221197 | ||
| Expression of isoforms of NADPH oxidase components in rat pancreatic islets | Q40231191 | ||
| Rho guanosine diphosphate-dissociation inhibitor plays a negative modulatory role in glucose-stimulated insulin secretion | Q40348059 | ||
| Ceramide induces mitochondrial abnormalities in insulin-secreting INS-1 cells: potential mechanisms underlying ceramide-mediated metabolic dysfunction of the beta cell | Q40379415 | ||
| Novel regulation by Rac1 of glucose- and forskolin-induced insulin secretion in INS-1 beta-cells | Q40596974 | ||
| Mastoparan-induced insulin secretion from insulin-secreting betaTC3 and INS-1 cells: evidence for its regulation by Rho subfamily of G proteins | Q40637060 | ||
| Subcellular localization and kinetic characterization of guanine nucleotide binding proteins in normal rat and human pancreatic islets and transformed beta cells | Q41454034 | ||
| The small GTP-binding proteins in the cytosol of insulin-secreting cells are complexed to GDP dissociation inhibitor proteins | Q41603615 | ||
| Pancreatic islet beta-cell and oxidative stress: the importance of glutathione peroxidase | Q42585037 | ||
| Pancreatic beta-cells express phagocyte-like NAD(P)H oxidase | Q44453013 | ||
| Association of NAD(P)H oxidase with glucose-induced insulin secretion by pancreatic beta-cells. | Q46160753 | ||
| Angiotensin II induces superoxide generation via NAD(P)H oxidase activation in isolated rat pancreatic islets. | Q46199397 | ||
| Chardonnay grape seed procyanidin extract supplementation prevents high-fat diet-induced obesity in hamsters by improving adipokine imbalance and oxidative stress markers. | Q46227309 | ||
| Pancreatic islets are very poor in rectifying oxidative DNA damage | Q46434584 | ||
| Palmitate-induced apoptosis in cultured bovine retinal pericytes: roles of NAD(P)H oxidase, oxidant stress, and ceramide. | Q46513293 | ||
| Increased expression of NAD(P)H oxidase in islets of animal models of Type 2 diabetes and its improvement by an AT1 receptor antagonist | Q46515498 | ||
| Leptin regulates cardiomyocyte contractile function through endothelin-1 receptor-NADPH oxidase pathway | Q46870251 | ||
| Oral taurine but not N-acetylcysteine ameliorates NEFA-induced impairment in insulin sensitivity and beta cell function in obese and overweight, non-diabetic men. | Q46890774 | ||
| NAD(P)H oxidase participates in the palmitate-induced superoxide production and insulin secretion by rat pancreatic islets. | Q54648636 | ||
| Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1 | Q59053220 | ||
| Regulation of pancreatic -cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway | Q63349280 | ||
| Exacerbation of albuminuria and renal fibrosis in subtotal renal ablation model of adiponectin-knockout mice | Q64377067 | ||
| Selective inhibitors of GTP synthesis impede exocytotic insulin release from intact rat islets | Q67883223 | ||
| Subcellular localization of the human neutrophil NADPH oxidase. b-Cytochrome and associated flavoprotein | Q71300519 | ||
| Targeting of Rac1 to the phagocyte membrane is sufficient for the induction of NADPH oxidase assembly | Q73010796 | ||
| Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress | Q79880676 | ||
| ADP-ribosylation factor 6 regulates insulin secretion through plasma membrane phosphatidylinositol 4,5-bisphosphate | Q30485892 | ||
| NADPH oxidase 2-derived reactive oxygen species mediate FFAs-induced dysfunction and apoptosis of β-cells via JNK, p38 MAPK and p53 pathways | Q30994890 | ||
| Reactive oxygen species as a signal in glucose-stimulated insulin secretion | Q33280759 | ||
| A dual role for IQGAP1 in regulating exocytosis | Q33316273 | ||
| Rac1 regulates pancreatic islet morphogenesis | Q33397843 | ||
| Differential phosphorylation of RhoGDI mediates the distinct cycling of Cdc42 and Rac1 to regulate second-phase insulin secretion | Q33673544 | ||
| Novel aspects of the roles of Rac1 GTPase in the cardiovascular system | Q33746458 | ||
| Small G proteins in islet beta-cell function | Q33779672 | ||
| Deficiency of rac1 blocks NADPH oxidase activation, inhibits endoplasmic reticulum stress, and reduces myocardial remodeling in a mouse model of type 1 diabetes | Q34024314 | ||
| Tiam1/Rac1 signaling pathway mediates palmitate-induced, ceramide-sensitive generation of superoxides and lipid peroxides and the loss of mitochondrial membrane potential in pancreatic beta-cells. | Q34055584 | ||
| A prenylated p47phox-p67phox-Rac1 chimera is a Quintessential NADPH oxidase activator: membrane association and functional capacity | Q34055834 | ||
| Phagocyte-like NADPH oxidase promotes cytokine-induced mitochondrial dysfunction in pancreatic β-cells: evidence for regulation by Rac1. | Q34502151 | ||
| Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation | Q34720092 | ||
| Protein prenylation in glucose-induced insulin secretion from the pancreatic islet beta cell: a perspective | Q34720513 | ||
| Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 β-cells and rat islets. | Q34778112 | ||
| NAD(P)H oxidase activation: a potential target mechanism for diabetic vascular complications, progressive beta-cell dysfunction and metabolic syndrome | Q36198742 | ||
| Regulation of NADPH oxidases: the role of Rac proteins | Q36412266 | ||
| NADPH oxidases: new kids on the block | Q36502608 | ||
| Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity | Q36856230 | ||
| Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism | Q36861002 | ||
| Glucolipotoxicity: fuel excess and beta-cell dysfunction. | Q36861036 | ||
| Functions of Rac GTPases during neuronal development. | Q37030405 | ||
| NOX family NADPH oxidases in liver and in pancreatic islets: a role in the metabolic syndrome and diabetes? | Q37269522 | ||
| Rac1 is required for cardiomyocyte apoptosis during hyperglycemia | Q37360478 | ||
| Rac1 GTPase: a "Rac" of all trades. | Q37371665 | ||
| Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins | Q37417286 | ||
| beta-Cell-specific overexpression of glutathione peroxidase preserves intranuclear MafA and reverses diabetes in db/db mice | Q37418222 | ||
| Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic beta cell | Q37610011 | ||
| Peptide-based inhibitors of the phagocyte NADPH oxidase | Q37761414 | ||
| Reactive oxygen species and uncoupling protein 2 in pancreatic β-cell function. | Q37804465 | ||
| Islets and their antioxidant defense | Q37811736 | ||
| Lipid-induced pancreatic β-cell dysfunction: focus on in vivo studies | Q37813877 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pharmacology | Q128406 |
| cell function | Q95674809 | ||
| P304 | page(s) | 965-975 | |
| P577 | publication date | 2011-02-12 | |
| P1433 | published in | Biochemical Pharmacology | Q864229 |
| P1476 | title | Friendly, and not so friendly, roles of Rac1 in islet β-cell function: lessons learnt from pharmacological and molecular biological approaches | |
| P478 | volume | 81 |
| Q36494177 | A lack of 'glue' misplaces Rab27A to cause islet dysfunction in diabetes |
| Q38257747 | Advances and strategies in NADPH oxidase inhibitors and activators patents |
| Q92888310 | Autophagy-induced degradation of Notch1, achieved through intermittent fasting, may promote beta cell neogenesis: implications for reversal of type 2 diabetes |
| Q37660944 | Deoxysphingolipids: β-cell, beware of these new kids on the block |
| Q35236262 | EHT 1864, a small molecule inhibitor of Ras-related C3 botulinum toxin substrate 1 (Rac1), attenuates glucose-stimulated insulin secretion in pancreatic β-cells. |
| Q34319297 | Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion |
| Q38951021 | Exposure to chronic hyperglycemic conditions results in Ras-related C3 botulinum toxin substrate 1 (Rac1)-mediated activation of p53 and ATM kinase in pancreatic β-cells. |
| Q90260794 | GPCRs, G Proteins, and Their Impact on β-cell Function |
| Q46552337 | Glucotoxicity promotes aberrant activation and mislocalization of Ras-related C3 botulinum toxin substrate 1 [Rac1] and metabolic dysfunction in pancreatic islet β-cells: reversal of such metabolic defects by metformin |
| Q28584125 | High glucose exposure promotes activation of protein phosphatase 2A in rodent islets and INS-1 832/13 β-cells by increasing the posttranslational carboxylmethylation of its catalytic subunit |
| Q53643789 | Hydrogen sulfide enhances pancreatic β-cell differentiation from human tooth under normal and glucotoxic conditions. |
| Q35404856 | Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet |
| Q39262708 | L- threo -C6-pyridinium-ceramide bromide, a novel cationic ceramide, induces NADPH oxidase activation, mitochondrial dysfunction and loss in cell viability in INS 832/13 β-cells |
| Q47599220 | Metabolic Stress Induces Caspase-3 Mediated Degradation and Inactivation of Farnesyl and Geranylgeranyl Transferase Activities in Pancreatic β-Cells. |
| Q46509939 | NSC23766, a Known Inhibitor of Tiam1-Rac1 Signaling Module, Prevents the Onset of Type 1 Diabetes in the NOD Mouse Model. |
| Q43080783 | Neurotrophin Signaling Is Required for Glucose-Induced Insulin Secretion |
| Q38886177 | Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic β-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxin substrate 1 (Rac1). |
| Q39253920 | Phagocytic NADPH oxidase links ARNO-Arf6 signaling pathway in glucose-stimulated insulin secretion from the pancreatic β-cell |
| Q35190620 | Protein histidine [de]phosphorylation in insulin secretion: abnormalities in models of impaired insulin secretion. |
| Q33361203 | Protein prenylation in islet β-cell function in health and diabetes: Putting the pieces of the puzzle together. |
| Q88532146 | RACking up ceramide-induced islet β-cell dysfunction |
| Q37464933 | Rac1-NADPH oxidase signaling promotes CD36 activation under glucotoxic conditions in pancreatic beta cells |
| Q36755888 | Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin |
| Q42609911 | Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation. |
| Q64935603 | Rho GTPases-Emerging Regulators of Glucose Homeostasis and Metabolic Health. |
| Q47843056 | Role of G-proteins in islet function in health and diabetes |
| Q26795765 | Role of ZAC1 in transient neonatal diabetes mellitus and glucose metabolism |
| Q27026733 | Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells |
| Q46929681 | TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy. |
| Q91656284 | The Regulatory Role of Rac1, a Small Molecular Weight GTPase, in the Development of Diabetic Retinopathy |
| Q37062050 | The role of thioredoxin 1 in the mycophenolic acid-induced apoptosis of insulin-producing cells |
| Q39137143 | Tiam1/Vav2-Rac1 axis: A tug-of-war between islet function and dysfunction |
| Q39355907 | Transient neonatal diabetes mellitus gene Zac1 impairs insulin secretion in mice through Rasgrf1 |
| Q36113595 | VAV2, a guanine nucleotide exchange factor for Rac1, regulates glucose-stimulated insulin secretion in pancreatic beta cells. |
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